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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Nphs2 (spascer ID:170484)

Gene summary for Nphs2

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Nphs2

Gene ID

170484

Gene namenephrosis 2, podocin
SynonymsPDCN|SRN1
Cytomap1|1 G3
Type of geneprotein-coding
Descriptionpodocinnephrosis 2 homolog, podocin
Modification date20220510
UniProtAcc

Q91X05


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Nphs2

GO:0005886

plasma membrane

21873635

Component

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Spatial pattern events for Nphs2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Nphs2MouseKidneyCLP 340037972.19e-15
Nphs2MouseKidneyIRI 340037973.92e-15
Nphs2MouseKidneySham 340037974.30e-15
Nphs2MouseKidneyrep_1 348531512.42e-15
Nphs2MouseKidneyrep_2 348531513.38e-15
Nphs2MouseKidneyrep_3 348531512.94e-15
Nphs2MouseKidneyrep_4 348531514.07e-15
Nphs2MouseKidneyrep_5 348531513.18e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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boxplot
Kidney_rep_2_H&E
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Kidney_rep_3_H&E
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Kidney_rep_4_H&E
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Kidney_rep_5_H&E
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Spatial pattern pathway has Nphs2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseSpinal cordCN94_E1 3.8e-09
Nphs2GOBP_Epithelial_Cell_DifferentiationMouseSpinal cordCN94_E1 2.3e-07
Nphs2GOBP_ExcretionMouseSpinal cordCN94_E1 3.2e-09
Nphs2GOBP_Glomerulus_DevelopmentMouseSpinal cordCN94_E1 3.2e-06
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseSpinal cordCN94_E1 6.4e-07
Nphs2GOBP_Nephron_DevelopmentMouseSpinal cordCN94_E1 8.2e-06
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseSpinal cordCN94_E1 4.7e-06
Nphs2GOBP_Urogenital_System_DevelopmentMouseSpinal cordCN94_E1 2.7e-06
Nphs2GOBP_Cytoskeleton_OrganizationMouseSpinal cordL7bCN02_E1 8.3e-06
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseSpinal cordL7CN45_C1 1.8e-06
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseSpinal cordL7CN45_C1 3.7e-06
Nphs2GOBP_Epithelium_DevelopmentMouseSpinal cordL7CN45_C1 4.2e-06
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseSpinal cordL7CN45_C1 9.8e-08
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseSpinal cordL7CN45_C1 9.7e-06
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseSpinal cordL7CN45_C1 9.7e-06
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseSpinal cordL7CN45_C1 2.8e-09
Nphs2GOBP_Metanephros_DevelopmentMouseSpinal cordL7CN45_C1 1.2e-06
Nphs2GOBP_Actin_Filament_Based_ProcessMouseSpinal cordL7CN47_C1 3.4e-06
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseBrainrep_11 2.9e-05
Nphs2GOBP_ExcretionMouseBrainrep_21 1.9e-05
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseBrainrep_27 4.5e-09
Nphs2GOBP_Nephron_DevelopmentMouseBrainrep_27 1.1e-10
Nphs2GOBP_Urogenital_System_DevelopmentMouseBrainrep_27 1.1e-05
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseBrainrep_30 2.6e-06
Nphs2GOBP_Metanephros_DevelopmentMouseBrainrep_41 3.3e-06
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseBrainrep_42 5.3e-05
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseBrainrep_42 4.4e-05
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseBrainrep_61 9.5e-05
Nphs2GOBP_Actin_Filament_Based_ProcessMouseBrainrep_1 2.1e-24
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseBrainrep_1 3.4e-53
Nphs2GOBP_Cytoskeleton_OrganizationMouseBrainrep_1 1.1e-11
Nphs2GOBP_Epithelial_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseBrainrep_1 8.3e-44
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseBrainrep_1 5.6e-31
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseBrainrep_1 2.0e-36
Nphs2GOBP_Glomerulus_DevelopmentMouseBrainrep_1 1.1e-16
Nphs2GOBP_Metanephric_Nephron_DevelopmentMouseBrainrep_1 1.1e-07
Nphs2GOBP_Metanephros_DevelopmentMouseBrainrep_1 9.9e-13
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseBrainrep_39.8e-155
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseBrainrep_3 2.4e-79
Nphs2GOBP_Epithelial_Cell_DifferentiationMouseBrainrep_34.7e-108
Nphs2GOBP_Epithelium_DevelopmentMouseBrainrep_38.3e-102
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseBrainrep_3 1.0e-63
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseBrainrep_36.3e-143
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseBrainrep_38.4e-197
Nphs2GOBP_Nephron_DevelopmentMouseBrainrep_35.1e-166
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseBrainrep_3 3.2e-56
Nphs2GOBP_Urogenital_System_DevelopmentMouseBrainrep_32.4e-187
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseBrainrep_4 3.6e-20
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseBrainrep_7 1.8e-32
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseEmbryorep_4 3.5e-08
Nphs2GOBP_ExcretionMouseEmbryorep_6 9.3e-27
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseEmbryorep_6 6.9e-12
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseEmbryorep_14 8.6e-16
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseEmbryorep_14 8.8e-58
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseEmbryorep_14 8.7e-25
Nphs2GOBP_Glomerulus_DevelopmentMouseEmbryorep_14 4.7e-23
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseEmbryorep_14 1.0e-11
Nphs2GOBP_Metanephros_DevelopmentMouseEmbryorep_14 1.4e-12
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseEmbryorep_1 4.7e-71
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseEmbryorep_1 1.2e-75
Nphs2GOBP_Epithelial_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseEmbryorep_1 1.6e-18
Nphs2GOBP_Epithelium_DevelopmentMouseEmbryorep_1 1.7e-09
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseEmbryorep_11.6e-223
Nphs2GOBP_Metanephros_DevelopmentMouseEmbryorep_1 3.9e-35
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseEmbryorep_11.6e-213
Nphs2GOBP_Urogenital_System_DevelopmentMouseEmbryorep_1 1.8e-45
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseKidneyIRI 3.0e-26
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseKidneyIRI 2.6e-56
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseKidneyrep_1 3.7e-29
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseKidneyrep_22.1e-101
Nphs2GOBP_Actin_Filament_Based_ProcessMouseKidneyrep_22.6e-107
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseKidneyrep_2 1.6e-15
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseKidneyrep_2 1.7e-37
Nphs2GOBP_Cytoskeleton_OrganizationMouseKidneyrep_2 1.5e-44
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseKidneyrep_2 1.6e-96
Nphs2GOBP_Epithelial_Cell_DifferentiationMouseKidneyrep_24.2e-114
Nphs2GOBP_Epithelial_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseKidneyrep_2 1.3e-13
Nphs2GOBP_Epithelium_DevelopmentMouseKidneyrep_2 3.5e-92
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseKidneyrep_2 2.5e-11
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseKidneyrep_2 4.5e-09
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseKidneyrep_2 4.2e-66
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseKidneyrep_23.5e-119
Nphs2GOBP_Metanephros_DevelopmentMouseKidneyrep_2 4.9e-20
Nphs2GOBP_Nephron_DevelopmentMouseKidneyrep_2 9.3e-40
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseKidneyrep_2 1.0e-56
Nphs2GOBP_Urogenital_System_DevelopmentMouseKidneyrep_2 2.5e-57
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseLiverCN16-D1 2.3e-12
Nphs2GOBP_ExcretionMouseLiverCN16-D1 8.6e-08
Nphs2GOBP_Glomerulus_DevelopmentMouseLiverCN16-D2 4.8e-07
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseLiverCN73-C1 1.1e-09
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseLiverCN73-C1 2.8e-10
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseLiverrep_15 4.1e-17
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseLiverrep_15 3.8e-32
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseLiverrep_15 8.3e-19
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseLiverrep_15 3.4e-11
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseLiverrep_16 3.4e-11
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseLiverrep_16 1.0e-17
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseLiverrep_16 7.2e-12
Nphs2GOBP_Nephron_DevelopmentMouseLiverrep_16 4.5e-08
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseLiverrep_16 1.2e-13
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseBrainrep_11.5e-119
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseBrainrep_1 2.0e-08
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseLymphMS-1 1.7e-07
Nphs2GOBP_Actin_Filament_Based_ProcessMouseLymphMS-1 1.4e-10
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseLymphMS-1 5.7e-12
Nphs2GOBP_Cytoskeleton_OrganizationMouseLymphMS-1 1.8e-13
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseLymphMS-1 6.8e-13
Nphs2GOBP_Epithelial_Cell_DifferentiationMouseLymphMS-1 1.2e-07
Nphs2GOBP_Epithelial_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseLymphMS-1 9.9e-12
Nphs2GOBP_Epithelium_DevelopmentMouseLymphMS-1 8.5e-09
Nphs2GOBP_ExcretionMouseLymphMS-1 5.1e-11
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseLymphMS-1 4.0e-12
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseLymphMS-1 7.6e-09
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseLymphMS-1 1.5e-12
Nphs2GOBP_Glomerulus_DevelopmentMouseLymphMS-1 4.0e-14
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseLymphMS-1 2.3e-09
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseLymphMS-1 3.8e-07
Nphs2GOBP_Nephron_DevelopmentMouseLymphMS-1 2.8e-11
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseLymphMS-1 1.6e-10
Nphs2GOBP_Urogenital_System_DevelopmentMouseLymphMS-1 5.4e-09
Nphs2GOBP_Metanephros_DevelopmentMouseLymphPBS 8.7e-07
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseBrainrep_4 1.3e-08
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseBrainrep_4 6.7e-09
Nphs2GOBP_Urogenital_System_DevelopmentMouseBrainrep_7 8.1e-17
Nphs2GOBP_Glomerular_Epithelial_Cell_DevelopmentMouseBrainHP_ad_rep2 2.7e-10
Nphs2GOBP_Actin_Cytoskeleton_ReorganizationMouseBrainHP_ad_rep7 2.6e-08
Nphs2GOBP_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseBrainHP_ad_rep7 1.6e-29
Nphs2GOBP_Cytoskeleton_OrganizationMouseBrainHP_ad_rep7 5.3e-08
Nphs2GOBP_Epithelial_Cell_DevelopmentMouseBrainHP_ad_rep7 5.6e-12
Nphs2GOBP_Epithelial_Cell_DifferentiationMouseBrainHP_ad_rep7 1.7e-13
Nphs2GOBP_Epithelial_Cell_Differentiation_Involved_In_Kidney_DevelopmentMouseBrainHP_ad_rep7 1.1e-20
Nphs2GOBP_Epithelium_DevelopmentMouseBrainHP_ad_rep7 2.8e-08
Nphs2GOBP_ExcretionMouseBrainHP_ad_rep7 5.6e-14
Nphs2GOBP_Glomerular_Epithelial_Cell_DifferentiationMouseBrainHP_ad_rep7 5.1e-23
Nphs2GOBP_Glomerular_Epithelium_DevelopmentMouseBrainHP_ad_rep7 5.0e-23
Nphs2GOBP_Glomerulus_DevelopmentMouseBrainHP_ad_rep7 3.6e-17
Nphs2GOBP_Kidney_Epithelium_DevelopmentMouseBrainHP_ad_rep7 1.1e-25
Nphs2GOBP_Metanephric_Epithelium_DevelopmentMouseBrainHP_ad_rep7 6.2e-37
Nphs2GOBP_Metanephric_Glomerulus_DevelopmentMouseBrainHP_ad_rep7 2.1e-10
Nphs2GOBP_Metanephros_DevelopmentMouseBrainHP_ad_rep7 7.4e-20
Nphs2GOBP_Nephron_DevelopmentMouseBrainHP_ad_rep7 3.2e-39
Nphs2GOBP_Nephron_Epithelium_DevelopmentMouseBrainHP_ad_rep7 6.2e-39
Nphs2GOBP_Urogenital_System_DevelopmentMouseBrainHP_ad_rep7 3.6e-14
Nphs2GOBP_Actin_Filament_Based_ProcessMouseBrainHP_polb_rep9 3.0e-07
Nphs2GOBP_Cell_Differentiation_Involved_In_Metanephros_DevelopmentMouseBrainHP_polb_rep9 2.5e-10
Nphs2GOBP_Metanephric_Nephron_DevelopmentMouseBrainHP_polb_rep9 8.1e-21

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Nphs2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Nphs2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Nphs2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Nphs2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Nphs2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource