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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Igfbp4 (spascer ID:16010)

Gene summary for Igfbp4

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Igfbp4

Gene ID

16010

Gene nameinsulin-like growth factor binding protein 4
SynonymsAI875747|Deb2|IBP-4|IGFBP-4
Cytomap11|11 D
Type of geneprotein-coding
Descriptioninsulin-like growth factor-binding protein 4Band 3AIGF-binding protein 4differentially expressed in B16F10 2
Modification date20220424
UniProtAcc

P47879


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Igfbp4

GO:0005615

extracellular space

21873635

Component
Igfbp4

GO:0031994

insulin-like growth factor I binding

21873635

Function
Igfbp4

GO:0031995

insulin-like growth factor II binding

21873635

Function
Igfbp4

GO:0043567

regulation of insulin-like growth factor receptor signaling pathway

21873635

Process

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Spatial pattern events for Igfbp4

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Igfbp4MouseBrainS1 344135152.07e-15
Igfbp4MouseBrainS2 344135151.56e-15
Igfbp4MouseBrainS3 344135151.64e-15
Igfbp4MouseBrainS4 344135151.37e-15
Igfbp4MouseBrainS6 344135151.46e-15
Igfbp4MouseBrainS7 344135151.55e-15
Igfbp4MouseBrain02A 326376227.02e-11
Igfbp4MouseBrain05A 326376221.47e-07
Igfbp4MouseBrain07A 326376226.44e-12
Igfbp4MouseBrain07B 326376222.62e-13
Igfbp4MouseBrain09A 326376221.52e-10
Igfbp4MouseBrain09B 326376221.82e-12
Igfbp4MouseBrain10B 326376226.59e-06
Igfbp4MouseBrain11A 326376221.94e-08
Igfbp4MouseBrain12A 326376222.09e-14
Igfbp4MouseBrain12B 326376221.20e-14
Igfbp4MouseBrain13A 326376227.70e-08
Igfbp4MouseBrain13B 326376221.72e-14
Igfbp4MouseBrain14A 326376221.38e-14
Igfbp4MouseBrain14B 326376221.35e-14
Igfbp4MouseBrain15A 326376222.43e-14
Igfbp4MouseBrain15B 326376227.32e-13
Igfbp4MouseBrain16A 326376221.75e-14
Igfbp4MouseBrain16B 326376223.51e-14
Igfbp4MouseBrain17A 326376221.19e-14
Igfbp4MouseBrain17B 326376221.32e-14
Igfbp4MouseBrain18A 326376221.20e-14
Igfbp4MouseBrain18B 326376221.09e-12
Igfbp4MouseBrain19A 326376221.35e-14
Igfbp4MouseBrain19B 326376221.36e-14
Igfbp4MouseBrain20A 326376221.49e-14
Igfbp4MouseBrain20B 326376222.93e-14
Igfbp4MouseBrain21A 326376221.43e-14
Igfbp4MouseBrain21B 326376221.37e-14
Igfbp4MouseBrain22A 326376228.87e-15
Igfbp4MouseBrain22B 326376228.81e-15
Igfbp4MouseBrain23A 326376222.77e-14
Igfbp4MouseBrain23B 326376221.10e-14
Igfbp4MouseBrain24A 326376221.61e-14
Igfbp4MouseBrain24B 326376221.40e-14
Igfbp4MouseBrain25A 326376221.86e-14
Igfbp4MouseBrain26A 326376222.20e-14
Igfbp4MouseBrain26B 326376223.04e-14
Igfbp4MouseBrain27A 326376227.93e-14
Igfbp4MouseBrain27B 326376223.31e-14
Igfbp4MouseBrain28A 326376221.06e-14
Igfbp4MouseBrain28B 326376221.24e-14
Igfbp4MouseBrain29A 326376226.92e-11
Igfbp4MouseBrain29B 326376221.08e-14
Igfbp4MouseBrain30A 326376222.02e-08
Igfbp4MouseBrain31A 326376222.61e-14
Igfbp4MouseBrain32A 326376225.70e-12
Igfbp4MouseBrain33A 326376222.59e-14
Igfbp4MouseBrain33B 326376223.35e-14
Igfbp4MouseBrain34A 326376223.24e-07
Igfbp4MouseBrain34B 326376221.25e-09
Igfbp4MouseBrain37A 326376224.76e-11
Igfbp4MouseBrain37B 326376223.73e-07
Igfbp4MouseBrainrep_1 351413742.02e-15
Igfbp4MouseBrainrep_2 351413741.69e-15
Igfbp4MouseBrainrep_3 351413741.64e-15
Igfbp4MouseBrainrep_4 351413741.57e-15
Igfbp4MouseBrainrep_5 351413741.47e-15
Igfbp4MouseBrainrep_6 351413741.73e-15
Igfbp4MouseEmbryo1D 342108872.07e-14
Igfbp4MouseEmbryo1E 342108872.17e-14
Igfbp4MouseEmbryo1F 342108872.30e-14
Igfbp4MouseEmbryo1G 342108876.15e-15
Igfbp4MouseEmbryo2G 342108871.43e-10
Igfbp4MouseEmbryo2H 342108879.15e-15
Igfbp4MouseEmbryo3D 342108872.41e-07
Igfbp4MouseEmbryo3F 342108872.00e-14
Igfbp4MouseEmbryo3G 342108871.88e-13
Igfbp4MouseEmbryo3H 342108875.51e-08
Igfbp4MouseEmbryo4C 342108878.07e-12
Igfbp4MouseEmbryo4D 342108871.11e-10
Igfbp4MouseEmbryo4E 342108874.53e-15
Igfbp4MouseEmbryorep_1 331887769.94e-15
Igfbp4MouseEmbryorep_2 331887761.97e-14
Igfbp4MouseEmbryorep_3 331887761.13e-14
Igfbp4MouseEmbryorep_4 331887762.84e-08
Igfbp4MouseEmbryorep_5 331887761.40e-14
Igfbp4MouseEmbryorep_6 331887763.99e-14
Igfbp4MouseEmbryorep_7 331887766.94e-15
Igfbp4MouseEmbryorep_12 331887764.84e-15
Igfbp4MouseEmbryorep_13 331887764.49e-15
Igfbp4MouseEmbryorep_14 331887769.36e-12
Igfbp4MouseEmbryorep_15 331887762.65e-06
Igfbp4MouseKidneyCLP 340037972.19e-15
Igfbp4MouseKidneyIRI 340037972.29e-15
Igfbp4MouseKidneySham 340037972.58e-15
Igfbp4MouseKidneyrep_1 348531512.42e-15
Igfbp4MouseKidneyrep_2 348531513.38e-15
Igfbp4MouseKidneyrep_3 348531512.94e-15
Igfbp4MouseKidneyrep_4 348531514.07e-15
Igfbp4MouseKidneyrep_5 348531513.18e-15
Igfbp4MouseKidneyrep_2 339761908.15e-07
Igfbp4MouseBrainrep_1 334690251.30e-15
Igfbp4MouseLiverrep_17 350210632.63e-08
Igfbp4MouseLiverrep_20 350210639.91e-15
Igfbp4MouseLiverrep_23 350210631.39e-14
Igfbp4MouseBrainrep_1 350277291.66e-15
Igfbp4MouseBrainrep_2 350277291.57e-15
Igfbp4MouseBrainrep_3 350277291.32e-15
Igfbp4MouseBrainrep_4 350277291.76e-15
Igfbp4MouseBrainrep_5 350277291.46e-15
Igfbp4MouseIntestinerep_1 351497216.08e-15
Igfbp4MouseIntestinerep_2 351497213.44e-15
Igfbp4MouseIntestinerep_3 351497213.25e-15
Igfbp4MouseIntestinerep_4 351497212.30e-15
Igfbp4MouseBrainB02_D1 327023141.50e-14
Igfbp4MouseBrainB02_E1 327023141.33e-14
Igfbp4MouseBrainB03_C2 327023149.50e-12
Igfbp4MouseBrainB03_D2 327023142.13e-14
Igfbp4MouseBrainB04_D1 327023146.50e-14
Igfbp4MouseBrainB04_E1 327023142.28e-14
Igfbp4MouseBrainB05_D2 327023149.05e-13
Igfbp4MouseBrainB05_E2 327023142.42e-14
Igfbp4MouseBrainB06_E1 327023142.62e-10
Igfbp4MouseBrainN02_C1 327023141.91e-10
Igfbp4MouseBrainN02_D1 327023141.76e-13
Igfbp4MouseBrainN03_C2 327023142.55e-14
Igfbp4MouseBrainN03_D2 327023141.38e-14
Igfbp4MouseBrainN04_D1 327023143.34e-14
Igfbp4MouseBrainN04_E1 327023143.65e-14
Igfbp4MouseBrainN05_C2 327023143.61e-14
Igfbp4MouseBrainN05_D2 327023141.93e-14
Igfbp4MouseBrainN06_D2 327023141.79e-09
Igfbp4MouseTesticlerep_3 347316001.63e-15
Igfbp4MouseTesticlerep_4 347316001.64e-15
Igfbp4MouseLymphMS-1 03.72e-14
Igfbp4MouseLymphMS-2 02.69e-14
Igfbp4MouseLymphPBS 03.34e-14
Igfbp4MouseLymphA1 03.29e-15
Igfbp4MouseLymphB1 03.66e-15
Igfbp4MouseLungrep_1 352908014.52e-15
Igfbp4MouseLungrep_2 352908017.23e-15
Igfbp4MouseLungrep_3 352908015.26e-15
Igfbp4MouseLungrep_4 352908013.04e-15
Igfbp4MouseBrainrep_1 352106241.74e-15
Igfbp4MouseBrainrep_2 352106241.74e-15
Igfbp4MouseBrainrep_3 352106241.82e-15
Igfbp4MouseBrainrep_4 352106242.34e-15
Igfbp4MouseBrainrep_5 352106242.07e-15
Igfbp4MouseBrainrep_6 352106242.05e-15
Igfbp4MouseBrainrep_7 352106241.87e-15
Igfbp4MouseBrainOFB_ad_rep1 330837254.03e-04
Igfbp4MouseBrainOFB_ad_rep2 330837256.73e-03
Igfbp4MouseBrainOFB_ad_rep4 330837252.52e-04
Igfbp4MouseBrainOFB_ad_rep5 330837251.70e-02
Igfbp4MouseBrainOFB_adpolb_rep2 330837252.28e-04
Igfbp4MouseBrainOFB_adpolb_rep3 330837251.33e-02
Igfbp4MouseBrainOFB_adpolb_rep4 330837256.57e-10
Igfbp4MouseBrainOFB_adpolb_rep5 330837254.85e-04
Igfbp4MouseBrainOFB_adpolb_rep6 330837251.41e-02
Igfbp4MouseBrainOFB_polb_rep6 330837251.99e-03
Igfbp4MouseBrainOFB_polb_rep7 330837252.23e-08
Igfbp4MouseBrainOFB_polb_rep8 330837252.48e-09
Igfbp4MouseBrainOFB_wt_rep1 330837255.73e-03
Igfbp4MouseBrainOFB_wt_rep2 330837254.79e-06
Igfbp4MouseBrainOFB_wt_rep5 330837256.86e-11
Igfbp4MouseBrainOFB_wt_rep6 330837251.69e-05

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_CLP_H&E
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Kidney_IRI_H&E
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Kidney_Sham_H&E
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Kidney_rep_1_H&E
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Kidney_rep_2_H&E
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Kidney_rep_3_H&E
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Kidney_rep_4_H&E
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Kidney_rep_5_H&E
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Kidney_rep_2_H&E
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Brain_rep_1_H&E
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Liver_rep_17_H&E
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Liver_rep_20_H&E
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Liver_rep_23_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_D1_H&E
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Brain_B02_E1_H&E
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Brain_B03_C2_H&E
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Brain_B03_D2_H&E
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Brain_B04_D1_H&E
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Brain_B04_E1_H&E
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Brain_B05_D2_H&E
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Brain_B05_E2_H&E
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Brain_B06_E1_H&E
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Brain_N02_C1_H&E
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Brain_N02_D1_H&E
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Brain_N03_C2_H&E
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Brain_N03_D2_H&E
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Brain_N04_D1_H&E
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Brain_N04_E1_H&E
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Brain_N05_C2_H&E
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Brain_N05_D2_H&E
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Brain_N06_D2_H&E
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Lung_rep_1_H&E
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Lung_rep_2_H&E
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Lung_rep_3_H&E
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Lung_rep_4_H&E
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Brain_OFB_ad_rep1_H&E
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Brain_OFB_ad_rep2_H&E
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Brain_OFB_ad_rep4_H&E
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Brain_OFB_ad_rep5_H&E
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Brain_OFB_adpolb_rep2_H&E
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Brain_OFB_adpolb_rep3_H&E
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Brain_OFB_adpolb_rep4_H&E
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Brain_OFB_adpolb_rep5_H&E
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Brain_OFB_adpolb_rep6_H&E
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Brain_OFB_polb_rep6_H&E
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Brain_OFB_polb_rep7_H&E
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Brain_OFB_polb_rep8_H&E
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Brain_OFB_wt_rep1_H&E
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Brain_OFB_wt_rep2_H&E
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Brain_OFB_wt_rep5_H&E
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Brain_OFB_wt_rep6_H&E
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Spatial pattern pathway has Igfbp4 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseSpinal cordCN94_E1 4.4e-07
Igfbp4GOBP_GrowthMouseSpinal cordCN94_E1 1.2e-06
Igfbp4GOBP_Inflammatory_ResponseMouseSpinal cordCN94_E1 8.2e-06
Igfbp4GOBP_Positive_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseSpinal cordL7CN44_C1 4.6e-12
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 4.6e-08
Igfbp4GOBP_Cell_Cell_SignalingMouseSpinal cordL7CN45_C1 3.5e-08
Igfbp4GOBP_Cell_GrowthMouseSpinal cordL7CN45_C1 8.5e-07
Igfbp4GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_SignalingMouseSpinal cordL7CN45_C1 5.6e-07
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseSpinal cordL7CN45_C1 4.2e-06
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 1.5e-08
Igfbp4GOBP_Mapk_CascadeMouseSpinal cordL7CN45_C1 1.7e-07
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseSpinal cordL7CN45_C1 5.1e-06
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseSpinal cordL7CN45_C1 4.8e-06
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseSpinal cordL7CN45_C1 4.8e-06
Igfbp4GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionMouseSpinal cordL7CN45_C1 8.5e-07
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseSpinal cordL7CN45_C1 4.2e-07
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseSpinal cordL7CN45_C1 5.2e-06
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.1e-08
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseSpinal cordL7CN45_C1 2.0e-07
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseSpinal cordL7CN45_C1 2.0e-07
Igfbp4GOBP_Regulation_Of_GrowthMouseSpinal cordL7CN45_C1 1.3e-06
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 8.0e-10
Igfbp4GOBP_Regulation_Of_Wnt_Signaling_PathwayMouseSpinal cordL7CN45_C1 8.2e-06
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.7e-07
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseSpinal cordL7CN45_C1 5.7e-08
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseSpinal cordL7CN45_C1 3.9e-06
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseSpinal cordL7CN47_C1 4.1e-06
Igfbp4GOBP_Positive_Regulation_Of_Mapk_CascadeMouseSpinal cordL7CN97_E2 4.9e-06
Igfbp4GOBP_Defense_ResponseMouseSpinal cordL8CN11_C1 3.3e-17
Igfbp4GOBP_Regulation_Of_Intracellular_Signal_TransductionMouseSpinal cordL8CN11_D1 5.6e-09
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseSpinal cordL8CN17_E1 1.6e-07
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseSpinal cordL8CN17_E1 3.7e-07
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseSpinal cordL8CN17_E1 8.3e-06
Igfbp4GOBP_Cell_GrowthMouseBrainrep_27 5.0e-07
Igfbp4GOBP_GrowthMouseBrainrep_27 5.5e-05
Igfbp4GOBP_Positive_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_36 7.0e-09
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_70 2.7e-05
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseBrainrep_71 2.7e-07
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseBrainrep_72 3.4e-06
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_75 6.4e-05
Igfbp4GOBP_Cell_Cell_SignalingMouseBrainrep_1 5.1e-48
Igfbp4GOBP_Cell_GrowthMouseBrainrep_1 2.4e-12
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseBrainrep_1 7.7e-17
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainrep_1 9.9e-07
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseBrainrep_1 3.1e-07
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseBrainrep_1 2.8e-21
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseBrainrep_1 5.0e-20
Igfbp4GOBP_Regulation_Of_Small_Molecule_Metabolic_ProcessMouseBrainrep_1 2.9e-09
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainrep_1 8.6e-14
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseBrainrep_1 7.3e-62
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseBrainrep_35.3e-174
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseBrainrep_3 1.4e-74
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseBrainrep_32.0e-124
Igfbp4GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_SignalingMouseBrainrep_3 3.3e-46
Igfbp4GOBP_Defense_ResponseMouseBrainrep_3 8.7e-77
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseBrainrep_31.4e-179
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseBrainrep_3 6.3e-54
Igfbp4GOBP_Inflammatory_ResponseMouseBrainrep_3 4.1e-53
Igfbp4GOBP_Mapk_CascadeMouseBrainrep_34.8e-123
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseBrainrep_3 9.2e-62
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseBrainrep_32.3e-180
Igfbp4GOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainrep_31.3e-138
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseBrainrep_37.8e-106
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseBrainrep_34.4e-159
Igfbp4GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionMouseBrainrep_33.3e-214
Igfbp4GOBP_Positive_Regulation_Of_Mapk_CascadeMouseBrainrep_34.0e-152
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseBrainrep_36.2e-128
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseBrainrep_3 4.0e-08
Igfbp4GOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainrep_31.3e-132
Igfbp4GOBP_Regulation_Of_Wnt_Signaling_PathwayMouseBrainrep_31.7e-164
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseBrainrep_3 2.7e-19
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_4 1.7e-11
Igfbp4GOBP_Positive_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_4 1.4e-96
Igfbp4GOBP_GrowthMouseBrainrep_7 5.0e-09
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseEmbryorep_6 5.3e-13
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseEmbryorep_14 1.1e-07
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseEmbryorep_14 1.1e-08
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseEmbryorep_14 1.4e-21
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseEmbryorep_14 3.9e-21
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseEmbryorep_14 5.8e-09
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseEmbryorep_14 1.7e-45
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseEmbryorep_14 3.8e-12
Igfbp4GOBP_Regulation_Of_Small_Molecule_Metabolic_ProcessMouseEmbryorep_14 4.1e-08
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseEmbryorep_14 1.1e-32
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseEmbryorep_1 2.6e-12
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseEmbryorep_1 5.6e-24
Igfbp4GOBP_Defense_ResponseMouseEmbryorep_1 5.2e-63
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseEmbryorep_1 0.0e+00
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseEmbryorep_19.4e-142
Igfbp4GOBP_GrowthMouseEmbryorep_1 5.0e-12
Igfbp4GOBP_Inflammatory_ResponseMouseEmbryorep_1 1.1e-20
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseEmbryorep_1 6.0e-95
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseEmbryorep_16.8e-306
Igfbp4GOBP_Negative_Regulation_Of_Response_To_StimulusMouseEmbryorep_1 1.1e-25
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseEmbryorep_1 5.6e-10
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseEmbryorep_1 2.0e-10
Igfbp4GOBP_Regulation_Of_GrowthMouseEmbryorep_1 7.1e-83
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseEmbryorep_1 1.4e-55
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseEmbryorep_2 1.4e-07
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseEmbryorep_32.7e-115
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseEmbryorep_4 9.7e-43
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseEmbryorep_4 2.6e-15
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseEmbryorep_4 2.6e-15
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseEmbryorep_41.3e-102
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseEmbryorep_6 1.7e-33
Igfbp4GOBP_Cell_GrowthMouseKidneyNep 1.1e-16
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyNep 4.4e-12
Igfbp4GOBP_GrowthMouseKidneyNep 1.1e-16
Igfbp4GOBP_Inflammatory_ResponseMouseKidneyNep 6.5e-32
Igfbp4GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionMouseKidneyNep 5.3e-07
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseKidneyNep 1.1e-39
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyNep 4.4e-12
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseKidneyrep_22.0e-101
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseKidneyrep_2 5.2e-99
Igfbp4GOBP_Cell_Cell_SignalingMouseKidneyrep_2 6.2e-72
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseKidneyrep_2 2.1e-78
Igfbp4GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_SignalingMouseKidneyrep_2 6.7e-89
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseKidneyrep_2 2.0e-96
Igfbp4GOBP_Defense_ResponseMouseKidneyrep_26.8e-127
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyrep_2 1.5e-13
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseKidneyrep_2 1.8e-43
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseKidneyrep_22.6e-109
Igfbp4GOBP_Inflammatory_ResponseMouseKidneyrep_2 8.2e-77
Igfbp4GOBP_Mapk_CascadeMouseKidneyrep_2 1.1e-19
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseKidneyrep_24.3e-127
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseKidneyrep_2 1.3e-49
Igfbp4GOBP_Negative_Regulation_Of_Response_To_StimulusMouseKidneyrep_2 1.7e-39
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseKidneyrep_2 4.0e-40
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseKidneyrep_2 2.4e-65
Igfbp4GOBP_Positive_Regulation_Of_Mapk_CascadeMouseKidneyrep_2 1.8e-39
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseKidneyrep_2 3.4e-17
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseKidneyrep_2 7.2e-84
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseKidneyrep_2 2.3e-39
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseKidneyrep_2 6.2e-73
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseKidneyrep_2 2.3e-67
Igfbp4GOBP_Regulation_Of_Intracellular_Signal_TransductionMouseKidneyrep_2 1.4e-17
Igfbp4GOBP_Regulation_Of_Wnt_Signaling_PathwayMouseKidneyrep_2 5.2e-90
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseKidneyrep_2 1.8e-43
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyrep_2 2.5e-32
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseKidneyrep_2 1.2e-16
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseLiverCN16-D1 1.1e-10
Igfbp4GOBP_Positive_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseLiverCN16-D2 1.5e-07
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseLiverCN16-D2 2.3e-07
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseLiverCN16-E1 1.5e-08
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseLiverCN73-C1 1.7e-07
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseLiverCN73-C1 9.0e-07
Igfbp4GOBP_Defense_ResponseMouseLiverrep_16 8.0e-16
Igfbp4GOBP_Inflammatory_ResponseMouseLiverrep_16 3.5e-14
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseLiverrep_16 3.3e-07
Igfbp4GOBP_Regulation_Of_GrowthMouseLiverrep_16 1.5e-07
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLiverrep_16 1.8e-10
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseLiverrep_16 4.8e-07
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_1 1.3e-14
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_1 1.9e-29
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseLymphMS-1 8.5e-09
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseLymphMS-1 5.9e-10
Igfbp4GOBP_Cell_Cell_SignalingMouseLymphMS-1 9.7e-11
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseLymphMS-1 7.3e-10
Igfbp4GOBP_Cell_GrowthMouseLymphMS-1 4.5e-14
Igfbp4GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_SignalingMouseLymphMS-1 1.6e-11
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseLymphMS-1 8.5e-07
Igfbp4GOBP_Defense_ResponseMouseLymphMS-1 8.6e-18
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseLymphMS-1 1.6e-14
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseLymphMS-1 1.0e-07
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseLymphMS-1 1.3e-09
Igfbp4GOBP_GrowthMouseLymphMS-1 4.5e-14
Igfbp4GOBP_Inflammatory_ResponseMouseLymphMS-1 1.2e-12
Igfbp4GOBP_Mapk_CascadeMouseLymphMS-1 8.8e-20
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseLymphMS-1 9.5e-09
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseLymphMS-1 9.4e-09
Igfbp4GOBP_Negative_Regulation_Of_Response_To_StimulusMouseLymphMS-1 1.5e-11
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseLymphMS-1 1.0e-14
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseLymphMS-1 9.3e-09
Igfbp4GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionMouseLymphMS-1 2.3e-12
Igfbp4GOBP_Positive_Regulation_Of_Mapk_CascadeMouseLymphMS-1 2.7e-14
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseLymphMS-1 2.3e-12
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseLymphMS-1 1.3e-15
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseLymphMS-1 8.1e-12
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseLymphMS-1 1.5e-09
Igfbp4GOBP_Regulation_Of_GrowthMouseLymphMS-1 8.9e-15
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseLymphMS-1 1.3e-07
Igfbp4GOBP_Regulation_Of_Intracellular_Signal_TransductionMouseLymphMS-1 1.0e-14
Igfbp4GOBP_Regulation_Of_Small_Molecule_Metabolic_ProcessMouseLymphMS-1 2.8e-14
Igfbp4GOBP_Regulation_Of_Wnt_Signaling_PathwayMouseLymphMS-1 6.2e-07
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseLymphMS-1 2.6e-11
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLymphMS-1 8.3e-14
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseLymphMS-1 5.7e-12
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseLymphPBS 6.0e-07
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseLungrep_1 5.4e-11
Igfbp4GOBP_Cell_GrowthMouseBrainrep_4 1.7e-17
Igfbp4GOBP_Canonical_Wnt_Signaling_PathwayMouseBrainHP_ad_rep7 1.2e-07
Igfbp4GOBP_Cell_Cell_SignalingMouseBrainHP_ad_rep7 1.6e-08
Igfbp4GOBP_Cellular_Carbohydrate_Metabolic_ProcessMouseBrainHP_ad_rep7 2.3e-08
Igfbp4GOBP_Defense_ResponseMouseBrainHP_ad_rep7 5.6e-10
Igfbp4GOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainHP_ad_rep7 2.5e-10
Igfbp4GOBP_Epithelial_Cell_ProliferationMouseBrainHP_ad_rep7 8.1e-09
Igfbp4GOBP_GrowthMouseBrainHP_ad_rep7 3.9e-09
Igfbp4GOBP_Negative_Regulation_Of_Canonical_Wnt_Signaling_PathwayMouseBrainHP_ad_rep7 4.0e-07
Igfbp4GOBP_Positive_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainHP_ad_rep7 1.4e-08
Igfbp4GOBP_Regulation_Of_GrowthMouseBrainHP_ad_rep7 5.8e-07
Igfbp4GOBP_Regulation_Of_Wnt_Signaling_PathwayMouseBrainHP_ad_rep7 3.8e-08
Igfbp4GOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainHP_ad_rep7 9.5e-09
Igfbp4GOBP_Type_B_Pancreatic_Cell_ProliferationMouseBrainHP_ad_rep7 3.3e-07
Igfbp4GOBP_Carbohydrate_Metabolic_ProcessMouseBrainHP_polb_rep9 1.6e-09
Igfbp4GOBP_Cell_Cell_Signaling_By_WntMouseBrainHP_polb_rep9 1.7e-14
Igfbp4GOBP_Cell_GrowthMouseBrainHP_polb_rep9 1.7e-11
Igfbp4GOBP_Cell_Surface_Receptor_Signaling_Pathway_Involved_In_Cell_Cell_SignalingMouseBrainHP_polb_rep9 1.2e-14
Igfbp4GOBP_Glucose_Metabolic_ProcessMouseBrainHP_polb_rep9 1.8e-10
Igfbp4GOBP_Inflammatory_ResponseMouseBrainHP_polb_rep9 2.0e-10
Igfbp4GOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 9.7e-15
Igfbp4GOBP_Monosaccharide_Metabolic_ProcessMouseBrainHP_polb_rep9 1.7e-09
Igfbp4GOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainHP_polb_rep9 3.1e-09
Igfbp4GOBP_Negative_Regulation_Of_SignalingMouseBrainHP_polb_rep9 1.4e-11
Igfbp4GOBP_Negative_Regulation_Of_Wnt_Signaling_PathwayMouseBrainHP_polb_rep9 4.7e-20
Igfbp4GOBP_Positive_Regulation_Of_Intracellular_Signal_TransductionMouseBrainHP_polb_rep9 1.7e-14
Igfbp4GOBP_Positive_Regulation_Of_Mapk_CascadeMouseBrainHP_polb_rep9 6.9e-10
Igfbp4GOBP_Positive_Regulation_Of_SignalingMouseBrainHP_polb_rep9 1.3e-14
Igfbp4GOBP_Post_Translational_Protein_ModificationMouseBrainHP_polb_rep9 5.1e-14
Igfbp4GOBP_Regulation_Of_Carbohydrate_Metabolic_ProcessMouseBrainHP_polb_rep9 5.0e-07
Igfbp4GOBP_Regulation_Of_Cellular_Carbohydrate_Metabolic_ProcessMouseBrainHP_polb_rep9 1.1e-09
Igfbp4GOBP_Regulation_Of_Glucose_Metabolic_ProcessMouseBrainHP_polb_rep9 5.5e-07
Igfbp4GOBP_Regulation_Of_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 4.5e-14
Igfbp4GOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainHP_polb_rep9 3.9e-11
Igfbp4GOBP_Small_Molecule_Metabolic_ProcessMouseBrainHP_polb_rep9 2.0e-09

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Igfbp4 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Igfbp4 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication
Igfbp4Lrp6Igfbp4_Lrp6BrainHPO_ad_rep1
Igfbp4Lrp6Igfbp4_Lrp6Kidneyrep_3

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Transcription factor for Igfbp4 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Igfbp4

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Igfbp4

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource