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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Igf2r (spascer ID:16004)

Gene summary for Igf2r

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Igf2r

Gene ID

16004

Gene nameinsulin-like growth factor 2 receptor
SynonymsAI661837|CD222|CI-MPR|M6P/IGF2R|Mpr300
Cytomap17 A1|17 8.64 cM
Type of geneprotein-coding
Descriptioncation-independent mannose-6-phosphate receptor300 kDa mannose 6-phosphate receptorCI Man-6-P receptorIGF-II receptorIGF-II/CI-MPRM6P/IGF2 receptorM6PRMPR 300cation-independent MPRinsulin-like growth factor II receptormannose-6-phosphate recepto
Modification date20220424
UniProtAcc

Q07113


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Igf2r

GO:0005520

insulin-like growth factor binding

21873635

Function
Igf2r

GO:0005770

late endosome

21873635

Component
Igf2r

GO:0005802

trans-Golgi network

21873635

Component
Igf2r

GO:0005886

plasma membrane

21873635

Component

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Spatial pattern events for Igf2r

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Igf2rMouseBrainS2 344135152.88e-06
Igf2rMouseBrainS4 344135153.35e-06
Igf2rMouseBrainrep_4 351413746.87e-08
Igf2rMouseBrain1_1 303854641.63e-15
Igf2rMouseBrain1_10 303854641.63e-15
Igf2rMouseBrain1_11 303854641.63e-15
Igf2rMouseBrain1_12 303854641.63e-15
Igf2rMouseBrain1_2 303854641.63e-15
Igf2rMouseBrain1_3 303854641.63e-15
Igf2rMouseBrain1_4 303854641.63e-15
Igf2rMouseBrain1_5 303854641.63e-15
Igf2rMouseBrain1_6 303854641.63e-15
Igf2rMouseBrain1_7 303854641.63e-15
Igf2rMouseBrain1_8 303854641.63e-15
Igf2rMouseBrain1_9 303854641.63e-15
Igf2rMouseBrain10_1 303854641.63e-15
Igf2rMouseBrain10_2 303854641.63e-15
Igf2rMouseBrain10_3 303854641.63e-15
Igf2rMouseBrain10_4 303854641.63e-15
Igf2rMouseBrain10_5 303854641.63e-15
Igf2rMouseBrain10_6 303854641.63e-15
Igf2rMouseBrain11_1 303854641.63e-15
Igf2rMouseBrain11_2 303854641.63e-15
Igf2rMouseBrain11_3 303854641.63e-15
Igf2rMouseBrain11_4 303854641.63e-15
Igf2rMouseBrain11_5 303854641.63e-15
Igf2rMouseBrain11_6 303854641.63e-15
Igf2rMouseBrain12_1 303854641.63e-15
Igf2rMouseBrain12_2 303854641.63e-15
Igf2rMouseBrain12_3 303854641.63e-15
Igf2rMouseBrain12_4 303854641.63e-15
Igf2rMouseBrain13_1 303854641.63e-15
Igf2rMouseBrain13_2 303854641.63e-15
Igf2rMouseBrain13_3 303854641.63e-15
Igf2rMouseBrain13_4 303854641.63e-15
Igf2rMouseBrain14_1 303854641.63e-15
Igf2rMouseBrain14_2 303854641.63e-15
Igf2rMouseBrain14_3 303854641.63e-15
Igf2rMouseBrain14_4 303854641.63e-15
Igf2rMouseBrain15_1 303854641.63e-15
Igf2rMouseBrain15_2 303854641.63e-15
Igf2rMouseBrain15_3 303854641.63e-15
Igf2rMouseBrain15_4 303854641.63e-15
Igf2rMouseBrain16_1 303854641.63e-15
Igf2rMouseBrain16_2 303854641.63e-15
Igf2rMouseBrain16_3 303854641.63e-15
Igf2rMouseBrain16_4 303854641.63e-15
Igf2rMouseBrain17_1 303854641.63e-15
Igf2rMouseBrain17_2 303854641.63e-15
Igf2rMouseBrain17_3 303854641.63e-15
Igf2rMouseBrain17_4 303854641.63e-15
Igf2rMouseBrain18_1 303854641.63e-15
Igf2rMouseBrain18_2 303854641.63e-15
Igf2rMouseBrain18_3 303854641.63e-15
Igf2rMouseBrain18_4 303854641.63e-15
Igf2rMouseBrain19_1 303854641.63e-15
Igf2rMouseBrain19_2 303854641.63e-15
Igf2rMouseBrain19_3 303854641.63e-15
Igf2rMouseBrain19_4 303854641.63e-15
Igf2rMouseBrain2_1 303854641.63e-15
Igf2rMouseBrain2_10 303854641.63e-15
Igf2rMouseBrain2_11 303854641.63e-15
Igf2rMouseBrain2_12 303854641.63e-15
Igf2rMouseBrain2_2 303854641.63e-15
Igf2rMouseBrain2_3 303854641.63e-15
Igf2rMouseBrain2_4 303854641.63e-15
Igf2rMouseBrain2_5 303854641.63e-15
Igf2rMouseBrain2_6 303854641.63e-15
Igf2rMouseBrain2_7 303854641.63e-15
Igf2rMouseBrain2_8 303854641.63e-15
Igf2rMouseBrain2_9 303854641.63e-15
Igf2rMouseBrain20_1 303854641.63e-15
Igf2rMouseBrain20_2 303854641.63e-15
Igf2rMouseBrain20_3 303854641.63e-15
Igf2rMouseBrain20_4 303854641.63e-15
Igf2rMouseBrain21_1 303854641.63e-15
Igf2rMouseBrain21_2 303854641.63e-15
Igf2rMouseBrain21_3 303854641.63e-15
Igf2rMouseBrain21_4 303854641.63e-15
Igf2rMouseBrain22_1 303854641.63e-15
Igf2rMouseBrain22_2 303854641.63e-15
Igf2rMouseBrain22_3 303854641.63e-15
Igf2rMouseBrain22_4 303854641.63e-15
Igf2rMouseBrain23_1 303854641.63e-15
Igf2rMouseBrain23_2 303854641.63e-15
Igf2rMouseBrain23_3 303854641.63e-15
Igf2rMouseBrain23_4 303854641.63e-15
Igf2rMouseBrain24_1 303854641.63e-15
Igf2rMouseBrain24_2 303854641.63e-15
Igf2rMouseBrain24_3 303854641.63e-15
Igf2rMouseBrain24_4 303854641.63e-15
Igf2rMouseBrain25_1 303854641.63e-15
Igf2rMouseBrain25_2 303854641.63e-15
Igf2rMouseBrain25_3 303854641.63e-15
Igf2rMouseBrain25_4 303854641.63e-15
Igf2rMouseBrain26_1 303854641.63e-15
Igf2rMouseBrain26_2 303854641.63e-15
Igf2rMouseBrain26_3 303854641.63e-15
Igf2rMouseBrain26_4 303854641.63e-15
Igf2rMouseBrain27_1 303854641.63e-15
Igf2rMouseBrain27_2 303854641.63e-15
Igf2rMouseBrain28_1 303854641.63e-15
Igf2rMouseBrain28_2 303854641.63e-15
Igf2rMouseBrain28_3 303854641.63e-15
Igf2rMouseBrain28_4 303854641.63e-15
Igf2rMouseBrain29_1 303854641.63e-15
Igf2rMouseBrain29_2 303854641.63e-15
Igf2rMouseBrain29_3 303854641.63e-15
Igf2rMouseBrain29_4 303854641.63e-15
Igf2rMouseBrain3_1 303854641.63e-15
Igf2rMouseBrain3_2 303854641.63e-15
Igf2rMouseBrain3_3 303854641.63e-15
Igf2rMouseBrain3_4 303854641.63e-15
Igf2rMouseBrain3_5 303854641.63e-15
Igf2rMouseBrain3_6 303854641.63e-15
Igf2rMouseBrain30_1 303854641.63e-15
Igf2rMouseBrain30_2 303854641.63e-15
Igf2rMouseBrain30_3 303854641.63e-15
Igf2rMouseBrain30_4 303854641.63e-15
Igf2rMouseBrain31_1 303854641.63e-15
Igf2rMouseBrain31_2 303854641.63e-15
Igf2rMouseBrain31_3 303854641.63e-15
Igf2rMouseBrain31_4 303854641.63e-15
Igf2rMouseBrain32_1 303854641.63e-15
Igf2rMouseBrain32_2 303854641.63e-15
Igf2rMouseBrain32_3 303854641.63e-15
Igf2rMouseBrain32_4 303854641.63e-15
Igf2rMouseBrain33_1 303854641.63e-15
Igf2rMouseBrain33_2 303854641.63e-15
Igf2rMouseBrain33_3 303854641.63e-15
Igf2rMouseBrain33_4 303854641.63e-15
Igf2rMouseBrain34_1 303854641.63e-15
Igf2rMouseBrain34_2 303854641.63e-15
Igf2rMouseBrain34_3 303854641.63e-15
Igf2rMouseBrain34_4 303854641.63e-15
Igf2rMouseBrain35_1 303854641.63e-15
Igf2rMouseBrain35_2 303854641.63e-15
Igf2rMouseBrain35_3 303854641.63e-15
Igf2rMouseBrain35_4 303854641.63e-15
Igf2rMouseBrain36_1 303854641.63e-15
Igf2rMouseBrain36_2 303854641.63e-15
Igf2rMouseBrain36_3 303854641.63e-15
Igf2rMouseBrain36_4 303854641.63e-15
Igf2rMouseBrain4_1 303854641.63e-15
Igf2rMouseBrain4_2 303854641.63e-15
Igf2rMouseBrain4_3 303854641.63e-15
Igf2rMouseBrain4_4 303854641.63e-15
Igf2rMouseBrain4_5 303854641.63e-15
Igf2rMouseBrain5_1 303854641.63e-15
Igf2rMouseBrain5_2 303854641.63e-15
Igf2rMouseBrain5_3 303854641.63e-15
Igf2rMouseBrain5_4 303854641.63e-15
Igf2rMouseBrain5_5 303854641.63e-15
Igf2rMouseBrain5_6 303854641.63e-15
Igf2rMouseBrain6_1 303854641.63e-15
Igf2rMouseBrain6_2 303854641.63e-15
Igf2rMouseBrain6_3 303854641.63e-15
Igf2rMouseBrain6_4 303854641.63e-15
Igf2rMouseBrain6_5 303854641.63e-15
Igf2rMouseBrain6_6 303854641.63e-15
Igf2rMouseBrain7_1 303854641.63e-15
Igf2rMouseBrain7_10 303854641.63e-15
Igf2rMouseBrain7_11 303854641.63e-15
Igf2rMouseBrain7_12 303854641.63e-15
Igf2rMouseBrain7_2 303854641.63e-15
Igf2rMouseBrain7_3 303854641.63e-15
Igf2rMouseBrain7_4 303854641.63e-15
Igf2rMouseBrain7_5 303854641.63e-15
Igf2rMouseBrain7_6 303854641.63e-15
Igf2rMouseBrain7_7 303854641.63e-15
Igf2rMouseBrain7_8 303854641.63e-15
Igf2rMouseBrain7_9 303854641.63e-15
Igf2rMouseBrain8_1 303854641.63e-15
Igf2rMouseBrain8_2 303854641.63e-15
Igf2rMouseBrain8_3 303854641.63e-15
Igf2rMouseBrain8_4 303854641.63e-15
Igf2rMouseBrain8_5 303854641.63e-15
Igf2rMouseBrain8_6 303854641.63e-15
Igf2rMouseBrain9_1 303854641.63e-15
Igf2rMouseBrain9_2 303854641.63e-15
Igf2rMouseBrain9_3 303854641.63e-15
Igf2rMouseBrain9_4 303854641.63e-15
Igf2rMouseBrain9_5 303854641.63e-15
Igf2rMouseBrain9_6 303854641.63e-15
Igf2rMouseEmbryo1D 342108871.46e-14
Igf2rMouseEmbryo1E 342108877.50e-15
Igf2rMouseEmbryo1F 342108871.90e-11
Igf2rMouseEmbryo1G 342108871.01e-14
Igf2rMouseEmbryo2G 342108873.30e-14
Igf2rMouseEmbryo2H 342108879.15e-15
Igf2rMouseEmbryo3D 342108879.51e-10
Igf2rMouseEmbryo3F 342108875.82e-15
Igf2rMouseEmbryo3G 342108871.07e-07
Igf2rMouseEmbryo3H 342108876.53e-06
Igf2rMouseEmbryo4D 342108877.75e-15
Igf2rMouseEmbryo4E 342108874.53e-15
Igf2rMouseEmbryorep_1 331887769.94e-15
Igf2rMouseEmbryorep_2 331887761.37e-14
Igf2rMouseEmbryorep_3 331887761.13e-14
Igf2rMouseEmbryorep_4 331887765.08e-15
Igf2rMouseEmbryorep_5 331887761.40e-14
Igf2rMouseEmbryorep_12 331887764.84e-15
Igf2rMouseEmbryorep_13 331887764.49e-15
Igf2rMouseEmbryorep_15 331887765.97e-15
Igf2rMouseKidneyCLP 340037971.94e-09
Igf2rMouseKidneyIRI 340037972.03e-13
Igf2rMouseKidneySham 340037977.83e-15
Igf2rMouseKidneyrep_1 339761904.39e-06
Igf2rMouseBrainrep_3 350277291.32e-15
Igf2rMouseBrainrep_5 350277295.00e-15
Igf2rMouseLymphA1 01.09e-08
Igf2rMouseLymphB1 03.66e-15
Igf2rMouseLungrep_4 352908018.22e-10

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_4_H&E
boxplot
boxplot
Kidney_CLP_H&E
boxplot
boxplot
Kidney_IRI_H&E
boxplot
boxplot
Kidney_Sham_H&E
boxplot
boxplot
Kidney_rep_1_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Brain_rep_5_H&E
boxplot
boxplot
Lung_rep_4_H&E
boxplot
boxplot


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Spatial pattern pathway has Igf2r envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Igf2rGOBP_Response_To_Retinoic_AcidMouseSpinal cordCN78_C1 3.9e-06
Igf2rGOBP_Developmental_Process_Involved_In_ReproductionMouseSpinal cordCN94_E1 3.2e-07
Igf2rGOBP_EndocytosisMouseSpinal cordCN94_E1 8.2e-06
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseSpinal cordCN94_E1 4.4e-07
Igf2rGOBP_Gamete_GenerationMouseSpinal cordCN94_E1 3.1e-07
Igf2rGOBP_Lysosomal_TransportMouseSpinal cordCN94_E1 6.6e-06
Igf2rGOBP_Male_Gamete_GenerationMouseSpinal cordCN94_E1 4.7e-06
Igf2rGOBP_ReproductionMouseSpinal cordCN94_E1 7.8e-08
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseSpinal cordL7bCN01_D2 6.8e-06
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseSpinal cordL7bCN02_E1 2.9e-06
Igf2rGOBP_Animal_Organ_RegenerationMouseSpinal cordL7CN45_C1 2.4e-07
Igf2rGOBP_Cell_ActivationMouseSpinal cordL7CN45_C1 8.5e-07
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseSpinal cordL7CN45_C1 9.9e-07
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 8.8e-08
Igf2rGOBP_Immune_Effector_ProcessMouseSpinal cordL7CN45_C1 3.1e-07
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseSpinal cordL7CN45_C1 1.5e-08
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 2.4e-06
Igf2rGOBP_Membrane_OrganizationMouseSpinal cordL7CN45_C1 2.7e-07
Igf2rGOBP_Multicellular_Organism_ReproductionMouseSpinal cordL7CN45_C1 7.1e-07
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseSpinal cordL7CN45_C1 2.2e-07
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseSpinal cordL7CN45_C1 6.7e-06
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseSpinal cordL7CN45_C1 8.5e-07
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseSpinal cordL7CN45_C1 2.2e-09
Igf2rGOBP_RegenerationMouseSpinal cordL7CN45_C1 2.8e-06
Igf2rGOBP_Response_To_LipidMouseSpinal cordL7CN45_C1 2.3e-07
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseSpinal cordL7CN45_C1 8.5e-07
Igf2rGOBP_SecretionMouseSpinal cordL7CN45_C1 8.1e-09
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseSpinal cordL7CN45_C1 5.7e-08
Igf2rGOBP_Vacuolar_TransportMouseSpinal cordL7CN45_C1 5.1e-07
Igf2rGOBP_ExocytosisMouseSpinal cordL7CN47_C1 7.4e-07
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseSpinal cordL7CN97_E2 1.2e-06
Igf2rGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseSpinal cordL7CN97_E2 6.8e-06
Igf2rGOBP_Post_Embryonic_DevelopmentMouseSpinal cordL7CN97_E2 6.4e-07
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseBrainrep_27 8.0e-06
Igf2rGOBP_Gamete_GenerationMouseBrainrep_27 5.2e-05
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_27 3.0e-05
Igf2rGOBP_Regulation_Of_Cell_DeathMouseBrainrep_27 6.3e-05
Igf2rGOBP_SecretionMouseBrainrep_27 8.9e-05
Igf2rGOBP_Post_Embryonic_DevelopmentMouseBrainrep_41 5.7e-06
Igf2rGOBP_Cell_ActivationMouseBrainrep_72 4.6e-06
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_75 6.4e-05
Igf2rGOBP_Response_To_Retinoic_AcidMouseBrainrep_75 7.2e-05
Igf2rGOBP_Cell_ActivationMouseBrainrep_1 1.8e-07
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_1 2.6e-13
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainrep_1 9.9e-07
Igf2rGOBP_ExocytosisMouseBrainrep_1 3.4e-73
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseBrainrep_1 4.5e-16
Igf2rGOBP_Gland_DevelopmentMouseBrainrep_1 4.1e-23
Igf2rGOBP_Immune_Effector_ProcessMouseBrainrep_1 1.5e-12
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_1 2.1e-07
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_1 1.3e-13
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseBrainrep_1 3.1e-13
Igf2rGOBP_SecretionMouseBrainrep_1 4.1e-45
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainrep_1 8.6e-14
Igf2rGOBP_Animal_Organ_RegenerationMouseBrainrep_33.5e-161
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseBrainrep_31.0e-116
Igf2rGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainrep_31.9e-146
Igf2rGOBP_Developmental_Process_Involved_In_ReproductionMouseBrainrep_32.9e-159
Igf2rGOBP_EndocytosisMouseBrainrep_3 2.6e-20
Igf2rGOBP_Gamete_GenerationMouseBrainrep_31.3e-194
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseBrainrep_34.1e-188
Igf2rGOBP_Lysosomal_TransportMouseBrainrep_3 1.6e-81
Igf2rGOBP_Male_Gamete_GenerationMouseBrainrep_31.6e-190
Igf2rGOBP_Membrane_OrganizationMouseBrainrep_3 1.9e-41
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseBrainrep_32.0e-110
Igf2rGOBP_Modulation_By_Host_Of_Viral_ProcessMouseBrainrep_32.0e-123
Igf2rGOBP_Multicellular_Organism_ReproductionMouseBrainrep_3 1.2e-58
Igf2rGOBP_Positive_Regulation_By_Host_Of_Viral_ProcessMouseBrainrep_32.1e-101
Igf2rGOBP_Post_Embryonic_DevelopmentMouseBrainrep_35.2e-204
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseBrainrep_3 3.1e-52
Igf2rGOBP_RegenerationMouseBrainrep_3 2.8e-93
Igf2rGOBP_Regulation_Of_Cell_DeathMouseBrainrep_37.6e-107
Igf2rGOBP_ReproductionMouseBrainrep_33.4e-125
Igf2rGOBP_Response_To_LipidMouseBrainrep_3 7.9e-86
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseBrainrep_3 6.3e-92
Igf2rGOBP_Vacuolar_TransportMouseBrainrep_33.9e-136
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_4 1.7e-11
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.3e-32
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_6 1.4e-16
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseEmbryorep_6 5.3e-13
Igf2rGOBP_Animal_Organ_RegenerationMouseEmbryorep_14 3.2e-24
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseEmbryorep_14 2.3e-25
Igf2rGOBP_Gamete_GenerationMouseEmbryorep_14 6.5e-07
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseEmbryorep_14 7.2e-30
Igf2rGOBP_Immune_Effector_ProcessMouseEmbryorep_14 3.3e-15
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 3.8e-12
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseEmbryorep_14 1.4e-41
Igf2rGOBP_Modulation_By_Host_Of_Viral_ProcessMouseEmbryorep_14 2.2e-43
Igf2rGOBP_Multicellular_Organism_ReproductionMouseEmbryorep_14 5.9e-07
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseEmbryorep_14 2.9e-28
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseEmbryorep_14 1.7e-32
Igf2rGOBP_Positive_Regulation_By_Host_Of_Viral_ProcessMouseEmbryorep_14 1.1e-31
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseEmbryorep_14 1.2e-15
Igf2rGOBP_Post_Embryonic_DevelopmentMouseEmbryorep_14 6.5e-07
Igf2rGOBP_RegenerationMouseEmbryorep_14 4.7e-08
Igf2rGOBP_Response_To_Retinoic_AcidMouseEmbryorep_14 3.9e-19
Igf2rGOBP_Animal_Organ_RegenerationMouseEmbryorep_12.2e-172
Igf2rGOBP_Male_Gamete_GenerationMouseEmbryorep_1 0.0e+00
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseEmbryorep_1 3.3e-68
Igf2rGOBP_Regulation_Of_Cell_DeathMouseEmbryorep_1 8.4e-30
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseEmbryorep_2 0.0e+00
Igf2rGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseEmbryorep_27.4e-121
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseEmbryorep_2 3.4e-34
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseEmbryorep_2 0.0e+00
Igf2rGOBP_Immune_Effector_ProcessMouseEmbryorep_2 1.7e-23
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseEmbryorep_2 0.0e+00
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseEmbryorep_21.2e-141
Igf2rGOBP_RegenerationMouseEmbryorep_2 4.0e-22
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseEmbryorep_3 0.0e+00
Igf2rGOBP_Gamete_GenerationMouseEmbryorep_32.1e-220
Igf2rGOBP_Multicellular_Organism_ReproductionMouseEmbryorep_38.7e-222
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseEmbryorep_3 0.0e+00
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseEmbryorep_32.7e-115
Igf2rGOBP_EndocytosisMouseKidneyNep 8.3e-23
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyNep 4.4e-12
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseKidneyNep 4.2e-26
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyNep 4.2e-26
Igf2rGOBP_Response_To_LipidMouseKidneyNep 6.3e-23
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyNep 6.8e-28
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyNep 4.4e-12
Igf2rGOBP_Animal_Organ_RegenerationMouseKidneyrep_2 2.5e-57
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseKidneyrep_2 2.8e-33
Igf2rGOBP_Cell_ActivationMouseKidneyrep_2 5.1e-83
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseKidneyrep_24.3e-101
Igf2rGOBP_Developmental_Process_Involved_In_ReproductionMouseKidneyrep_2 3.6e-46
Igf2rGOBP_EndocytosisMouseKidneyrep_21.4e-132
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseKidneyrep_2 1.5e-13
Igf2rGOBP_ExocytosisMouseKidneyrep_23.2e-107
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseKidneyrep_2 3.0e-37
Igf2rGOBP_Gamete_GenerationMouseKidneyrep_2 5.0e-33
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseKidneyrep_2 1.3e-24
Igf2rGOBP_Immune_Effector_ProcessMouseKidneyrep_23.4e-107
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseKidneyrep_22.7e-133
Igf2rGOBP_Lysosomal_TransportMouseKidneyrep_2 6.1e-84
Igf2rGOBP_Male_Gamete_GenerationMouseKidneyrep_2 5.8e-51
Igf2rGOBP_Membrane_OrganizationMouseKidneyrep_2 8.5e-74
Igf2rGOBP_Multicellular_Organism_ReproductionMouseKidneyrep_2 1.6e-53
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseKidneyrep_22.2e-110
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseKidneyrep_26.6e-105
Igf2rGOBP_Post_Embryonic_DevelopmentMouseKidneyrep_2 9.0e-20
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseKidneyrep_24.7e-166
Igf2rGOBP_RegenerationMouseKidneyrep_2 8.1e-59
Igf2rGOBP_ReproductionMouseKidneyrep_2 9.0e-46
Igf2rGOBP_Response_To_LipidMouseKidneyrep_21.1e-111
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseKidneyrep_26.6e-112
Igf2rGOBP_Response_To_Retinoic_AcidMouseKidneyrep_2 9.6e-39
Igf2rGOBP_SecretionMouseKidneyrep_2 1.6e-23
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseKidneyrep_2 2.5e-32
Igf2rGOBP_Vacuolar_TransportMouseKidneyrep_2 5.2e-99
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseLiverCN16-D1 6.8e-09
Igf2rGOBP_Animal_Organ_RegenerationMouseLiverCN16-D2 7.1e-10
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseLiverrep_15 2.4e-09
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLiverrep_16 1.6e-18
Igf2rGOBP_ExocytosisMouseLiverrep_16 8.5e-07
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseLiverrep_16 7.0e-09
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseLiverrep_16 6.8e-09
Igf2rGOBP_Modulation_By_Host_Of_Viral_ProcessMouseLiverrep_16 2.4e-11
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLiverrep_16 2.2e-20
Igf2rGOBP_Positive_Regulation_By_Host_Of_Viral_ProcessMouseLiverrep_16 1.3e-08
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseLiverrep_16 7.3e-07
Igf2rGOBP_Regulation_Of_Cell_DeathMouseLiverrep_16 2.0e-13
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLiverrep_16 1.8e-10
Igf2rGOBP_Animal_Organ_RegenerationMouseLiverrep_23 6.9e-27
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainrep_1 1.3e-14
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseIntestinerep_2 1.2e-12
Igf2rGOBP_Animal_Organ_RegenerationMouseLymphMS-1 4.6e-08
Igf2rGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseLymphMS-1 4.6e-18
Igf2rGOBP_Cell_ActivationMouseLymphMS-1 1.6e-18
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseLymphMS-1 9.7e-16
Igf2rGOBP_Developmental_Process_Involved_In_ReproductionMouseLymphMS-1 2.2e-10
Igf2rGOBP_EndocytosisMouseLymphMS-1 1.8e-21
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseLymphMS-1 1.6e-14
Igf2rGOBP_ExocytosisMouseLymphMS-1 1.4e-14
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseLymphMS-1 1.8e-08
Igf2rGOBP_Gamete_GenerationMouseLymphMS-1 7.7e-08
Igf2rGOBP_Gland_DevelopmentMouseLymphMS-1 1.7e-10
Igf2rGOBP_Immune_Effector_ProcessMouseLymphMS-1 1.6e-18
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseLymphMS-1 5.6e-21
Igf2rGOBP_Lysosomal_TransportMouseLymphMS-1 6.7e-08
Igf2rGOBP_Male_Gamete_GenerationMouseLymphMS-1 1.6e-08
Igf2rGOBP_Membrane_OrganizationMouseLymphMS-1 5.8e-20
Igf2rGOBP_Multicellular_Organism_ReproductionMouseLymphMS-1 1.1e-09
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseLymphMS-1 1.0e-18
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseLymphMS-1 6.6e-07
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseLymphMS-1 3.7e-07
Igf2rGOBP_Post_Embryonic_DevelopmentMouseLymphMS-1 1.9e-13
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseLymphMS-1 2.1e-11
Igf2rGOBP_RegenerationMouseLymphMS-1 4.3e-08
Igf2rGOBP_Regulation_Of_Cell_DeathMouseLymphMS-1 1.9e-12
Igf2rGOBP_ReproductionMouseLymphMS-1 1.1e-09
Igf2rGOBP_Response_To_LipidMouseLymphMS-1 8.6e-10
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseLymphMS-1 1.8e-09
Igf2rGOBP_Response_To_Retinoic_AcidMouseLymphMS-1 1.5e-14
Igf2rGOBP_SecretionMouseLymphMS-1 2.3e-12
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseLymphMS-1 8.3e-14
Igf2rGOBP_Vacuolar_TransportMouseLymphMS-1 1.1e-08
Igf2rGOBP_ReproductionMouseLungrep_1 9.6e-12
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseLungrep_1 1.2e-19
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainrep_4 2.9e-33
Igf2rGOBP_ExocytosisMouseBrainrep_4 2.4e-43
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseBrainrep_4 1.7e-17
Igf2rGOBP_Immune_Effector_ProcessMouseBrainrep_4 7.2e-15
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseBrainrep_4 6.4e-19
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseBrainrep_4 3.5e-20
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainrep_4 3.7e-62
Igf2rGOBP_Developmental_Process_Involved_In_ReproductionMouseBrainHP_ad_rep7 2.5e-08
Igf2rGOBP_Enzyme_Linked_Receptor_Protein_Signaling_PathwayMouseBrainHP_ad_rep7 2.5e-10
Igf2rGOBP_Gamete_GenerationMouseBrainHP_ad_rep7 1.3e-11
Igf2rGOBP_Gland_DevelopmentMouseBrainHP_ad_rep7 3.2e-13
Igf2rGOBP_Hepaticobiliary_System_DevelopmentMouseBrainHP_ad_rep7 4.6e-18
Igf2rGOBP_Lysosomal_TransportMouseBrainHP_ad_rep7 3.3e-09
Igf2rGOBP_Multicellular_Organism_ReproductionMouseBrainHP_ad_rep7 6.1e-08
Igf2rGOBP_Myeloid_Leukocyte_Mediated_ImmunityMouseBrainHP_ad_rep7 4.4e-14
Igf2rGOBP_Positive_Regulation_Of_Cell_DeathMouseBrainHP_ad_rep7 9.4e-07
Igf2rGOBP_Post_Embryonic_DevelopmentMouseBrainHP_ad_rep7 2.8e-15
Igf2rGOBP_Receptor_Mediated_EndocytosisMouseBrainHP_ad_rep7 1.4e-08
Igf2rGOBP_Regulation_Of_Cell_DeathMouseBrainHP_ad_rep7 1.6e-07
Igf2rGOBP_ReproductionMouseBrainHP_ad_rep7 7.9e-09
Igf2rGOBP_Response_To_LipidMouseBrainHP_ad_rep7 3.5e-07
Igf2rGOBP_Response_To_Oxygen_Containing_CompoundMouseBrainHP_ad_rep7 4.2e-09
Igf2rGOBP_SecretionMouseBrainHP_ad_rep7 1.6e-08
Igf2rGOBP_Transmembrane_Receptor_Protein_Tyrosine_Kinase_Signaling_PathwayMouseBrainHP_ad_rep7 9.5e-09
Igf2rGOBP_Vacuolar_TransportMouseBrainHP_ad_rep7 1.2e-09
Igf2rGOBP_Male_Gamete_GenerationMouseBrainHP_ad_rep8 8.4e-07
Igf2rGOBP_Biological_Process_Involved_In_Interaction_With_SymbiontMouseBrainHP_adpolb_rep1 2.8e-10
Igf2rGOBP_Modulation_By_Host_Of_Symbiont_ProcessMouseBrainHP_adpolb_rep1 2.0e-10
Igf2rGOBP_Modulation_By_Host_Of_Viral_ProcessMouseBrainHP_adpolb_rep1 5.8e-09
Igf2rGOBP_Positive_Regulation_By_Host_Of_Viral_ProcessMouseBrainHP_adpolb_rep1 5.9e-10
Igf2rGOBP_Animal_Organ_RegenerationMouseBrainHP_adpolb_rep3 8.7e-07
Igf2rGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainHP_polb_rep9 1.1e-12
Igf2rGOBP_Cell_ActivationMouseBrainHP_polb_rep9 1.5e-08
Igf2rGOBP_Cell_Activation_Involved_In_Immune_ResponseMouseBrainHP_polb_rep9 8.8e-09
Igf2rGOBP_EndocytosisMouseBrainHP_polb_rep9 3.2e-09
Igf2rGOBP_ExocytosisMouseBrainHP_polb_rep9 2.3e-13
Igf2rGOBP_G_Protein_Coupled_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 6.4e-16
Igf2rGOBP_Immune_Effector_ProcessMouseBrainHP_polb_rep9 1.0e-08
Igf2rGOBP_Insulin_Like_Growth_Factor_Receptor_Signaling_PathwayMouseBrainHP_polb_rep9 9.7e-15
Igf2rGOBP_Leukocyte_Mediated_ImmunityMouseBrainHP_polb_rep9 2.8e-07
Igf2rGOBP_Membrane_OrganizationMouseBrainHP_polb_rep9 1.4e-13
Igf2rGOBP_Myeloid_Leukocyte_ActivationMouseBrainHP_polb_rep9 2.6e-11
Igf2rGOBP_RegenerationMouseBrainHP_polb_rep9 8.7e-07
Igf2rGOBP_Response_To_Retinoic_AcidMouseBrainHP_wt_rep2 1.2e-07

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Igf2r function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Igf2r function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication
Igf2Igf2rIgf2_Igf2rBrain16A
PlgIgf2rPlg_Igf2rBrain7_11
PlauIgf2rPlau_Igf2rBrain7_11
Igf2Igf2rIgf2_Igf2rBrain7_11

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Transcription factor for Igf2r envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Igf2r

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Igf2r

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Igf2rC0024115Lung diseases2CTD_human
Igf2rC0235833Congenital diaphragmatic hernia2CTD_human
Igf2rC0265699Congenital hernia of foramen of Morgagni2CTD_human
Igf2rC0265700Congenital hernia of foramen of Bochdalek2CTD_human
Igf2rC0002395Alzheimer's Disease1CTD_human
Igf2rC0011265Presenile dementia1CTD_human
Igf2rC0023893Liver Cirrhosis, Experimental1CTD_human
Igf2rC0030567Parkinson Disease1CTD_human
Igf2rC0033578Prostatic Neoplasms1CTD_human
Igf2rC0242973Ventricular Dysfunction1CTD_human
Igf2rC0276496Familial Alzheimer Disease (FAD)1CTD_human
Igf2rC0376358Malignant neoplasm of prostate1CTD_human
Igf2rC0494463Alzheimer Disease, Late Onset1CTD_human
Igf2rC0546126Acute Confusional Senile Dementia1CTD_human
Igf2rC0553980Endomyocardial Fibrosis1CTD_human
Igf2rC0750900Alzheimer's Disease, Focal Onset1CTD_human
Igf2rC0750901Alzheimer Disease, Early Onset1CTD_human
Igf2rC0752347Lewy Body Disease1CTD_human
Igf2rC2239176Liver carcinoma1CGI;CTD_human