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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hsd11b2 (spascer ID:15484)

Gene summary for Hsd11b2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hsd11b2
	Gene ID	15484
	Gene name	hydroxysteroid 11-beta dehydrogenase 2
	Synonyms	11HSD2
	Cytomap	8 D3\|8 53.04 cM
	Type of gene	protein-coding
	Description	11-beta-hydroxysteroid dehydrogenase type 211-DH211-beta-HSD2NAD-dependent 11-beta-hydroxysteroid dehydrogenasecorticosteroid 11-beta-dehydrogenase isozyme 2
	Modification date	20220503
	UniProtAcc	P51661

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for Hsd11b2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hsd11b2	Mouse	Embryo	rep_2	33188776	3.23e-06
Hsd11b2	Mouse	Kidney	CLP	34003797	2.19e-15
Hsd11b2	Mouse	Kidney	IRI	34003797	2.29e-15
Hsd11b2	Mouse	Kidney	Sham	34003797	4.30e-15
Hsd11b2	Mouse	Kidney	rep_1	34853151	2.42e-15
Hsd11b2	Mouse	Kidney	rep_2	34853151	3.38e-15
Hsd11b2	Mouse	Kidney	rep_3	34853151	2.94e-15
Hsd11b2	Mouse	Kidney	rep_4	34853151	6.82e-15
Hsd11b2	Mouse	Kidney	rep_5	34853151	3.18e-15
Hsd11b2	Mouse	Kidney	rep_2	33976190	5.12e-07
Hsd11b2	Mouse	Intestine	rep_1	35149721	6.08e-15
Hsd11b2	Mouse	Intestine	rep_2	35149721	3.44e-15
Hsd11b2	Mouse	Intestine	rep_3	35149721	3.25e-15
Hsd11b2	Mouse	Intestine	rep_4	35149721	2.30e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Kidney_rep_2_H&E

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Spatial pattern pathway has Hsd11b2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Spinal cord	CN93_D2	2.2e-06
Hsd11b2	GOBP_Endocrine_Process	Mouse	Spinal cord	CN94_E1	3.0e-07
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Spinal cord	CN94_E1	1.3e-06
Hsd11b2	GOBP_Reproduction	Mouse	Spinal cord	CN94_E1	7.8e-08
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Spinal cord	CN94_E1	2.2e-06
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Spinal cord	CN94_E1	4.8e-06
Hsd11b2	GOBP_Response_To_Insulin	Mouse	Spinal cord	CN94_E1	1.1e-06
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	5.6e-06
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Spinal cord	CN94_E1	4.1e-06
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Spinal cord	L7CN45_C1	3.0e-06
Hsd11b2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Spinal cord	L7CN45_C1	9.1e-06
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Hsd11b2	GOBP_Renal_System_Process	Mouse	Spinal cord	L7CN45_C1	2.5e-07
Hsd11b2	GOBP_Response_To_Corticosteroid	Mouse	Spinal cord	L7CN45_C1	5.7e-06
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Hsd11b2	GOBP_Response_To_Food	Mouse	Spinal cord	L7CN45_C1	1.1e-08
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Hsd11b2	GOBP_Response_To_Oxygen_Levels	Mouse	Spinal cord	L7CN45_C1	8.9e-08
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Spinal cord	L7CN45_C1	2.8e-06
Hsd11b2	GOBP_Response_To_Steroid_Hormone	Mouse	Spinal cord	L7CN45_C1	6.8e-08
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Spinal cord	L7CN54_C1	1.8e-07
Hsd11b2	GOBP_Positive_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Spinal cord	L7CN85_E2	3.0e-06
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Spinal cord	L8CN17_E1	2.2e-06
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	rep_19	7.5e-06
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Brain	rep_21	1.5e-06
Hsd11b2	GOBP_Renal_System_Process	Mouse	Brain	rep_21	5.0e-06
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Brain	rep_42	1.5e-09
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Brain	rep_1	1.5e-106
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Brain	rep_1	1.3e-173
Hsd11b2	GOBP_Response_To_Abiotic_Stimulus	Mouse	Brain	rep_1	6.0e-28
Hsd11b2	GOBP_Response_To_Insulin	Mouse	Brain	rep_1	3.5e-07
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Brain	rep_3	2.0e-61
Hsd11b2	GOBP_Endocrine_Process	Mouse	Brain	rep_3	8.9e-13
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Brain	rep_3	4.4e-66
Hsd11b2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	rep_3	1.1e-62
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Brain	rep_3	8.2e-81
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Brain	rep_3	9.6e-61
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Brain	rep_3	1.7e-11
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	rep_3	2.6e-07
Hsd11b2	GOBP_Reproduction	Mouse	Brain	rep_3	3.4e-125
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	rep_3	6.4e-96
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	rep_3	2.2e-117
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Brain	rep_3	8.1e-134
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Brain	rep_3	7.9e-86
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	rep_3	2.5e-82
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	rep_3	3.4e-98
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	6.3e-92
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Brain	rep_3	1.8e-28
Hsd11b2	GOBP_Response_To_Steroid_Hormone	Mouse	Brain	rep_3	3.0e-66
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Brain	rep_3	3.4e-149
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Brain	rep_3	3.0e-174
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Brain	rep_4	7.7e-16
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Brain	rep_7	1.9e-35
Hsd11b2	GOBP_Response_To_Corticosteroid	Mouse	Brain	rep_7	3.1e-23
Hsd11b2	GOBP_Response_To_Oxygen_Levels	Mouse	Brain	rep_7	8.1e-12
Hsd11b2	GOBP_Endocrine_Process	Mouse	Embryo	rep_6	8.8e-10
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_6	2.4e-08
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Embryo	rep_6	9.8e-11
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Embryo	rep_14	2.2e-50
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Embryo	rep_14	4.1e-52
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Embryo	rep_14	3.8e-13
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_14	7.7e-16
Hsd11b2	GOBP_Positive_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Embryo	rep_14	5.6e-11
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Embryo	rep_14	1.6e-07
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Embryo	rep_14	3.2e-36
Hsd11b2	GOBP_Renal_System_Process	Mouse	Embryo	rep_14	1.6e-16
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Embryo	rep_14	6.2e-111
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Embryo	rep_14	5.1e-36
Hsd11b2	GOBP_Response_To_Food	Mouse	Embryo	rep_14	6.8e-65
Hsd11b2	GOBP_Response_To_Oxygen_Levels	Mouse	Embryo	rep_14	4.2e-19
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Embryo	rep_14	2.0e-24
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Embryo	rep_14	1.1e-10
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Embryo	rep_1	1.0e-146
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_1	1.5e-209
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Embryo	rep_1	2.5e-19
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Embryo	rep_1	5.6e-22
Hsd11b2	GOBP_Response_To_Steroid_Hormone	Mouse	Embryo	rep_1	1.9e-50
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Embryo	rep_1	1.1e-16
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Embryo	rep_3	3.6e-133
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Embryo	rep_3	0.0e+00
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Embryo	rep_3	8.6e-76
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Embryo	rep_4	1.2e-08
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Embryo	rep_5	1.1e-16
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Embryo	rep_6	2.0e-17
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Kidney	IRI	1.5e-08
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Kidney	IRI	1.8e-15
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Kidney	IRI	2.2e-07
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	IRI	9.0e-58
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	IRI	2.4e-84
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Hsd11b2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Kidney	Nep	1.6e-16
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	Nep	6.3e-23
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Kidney	Nep	6.3e-23
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Kidney	Nep	6.3e-23
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	Nep	6.8e-28
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	rep_1	2.1e-07
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Kidney	rep_2	1.4e-100
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Kidney	rep_2	3.9e-118
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Kidney	rep_2	2.2e-125
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Kidney	rep_2	3.0e-52
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Kidney	rep_2	8.0e-57
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Kidney	rep_2	5.1e-26
Hsd11b2	GOBP_Positive_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	rep_2	4.8e-72
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	rep_2	3.9e-99
Hsd11b2	GOBP_Renal_System_Process	Mouse	Kidney	rep_2	8.4e-46
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Kidney	rep_2	1.1e-67
Hsd11b2	GOBP_Reproduction	Mouse	Kidney	rep_2	9.0e-46
Hsd11b2	GOBP_Response_To_Corticosteroid	Mouse	Kidney	rep_2	4.3e-09
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	rep_2	1.1e-44
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Kidney	rep_2	3.8e-52
Hsd11b2	GOBP_Response_To_Food	Mouse	Kidney	rep_2	1.3e-42
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Kidney	rep_2	3.2e-12
Hsd11b2	GOBP_Response_To_Insulin	Mouse	Kidney	rep_2	3.0e-28
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Kidney	rep_2	1.1e-111
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	1.0e-56
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Kidney	rep_2	1.3e-60
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	6.6e-112
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Kidney	rep_2	1.4e-66
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Kidney	rep_2	6.2e-41
Hsd11b2	GOBP_Response_To_Steroid_Hormone	Mouse	Kidney	rep_2	4.5e-14
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Kidney	rep_2	2.4e-71
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-60
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Kidney	rep_4	1.8e-09
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	rep_4	1.0e-09
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Liver	CN16-D1	9.2e-07
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Liver	CN16-E1	6.8e-12
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Liver	CN73-C1	1.6e-12
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Liver	CN73-C1	1.7e-11
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Liver	CN73-C1	1.6e-07
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Liver	CN73-C1	3.4e-09
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Liver	rep_15	1.0e-07
Hsd11b2	GOBP_Endocrine_Process	Mouse	Liver	rep_16	4.8e-29
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Liver	rep_16	4.6e-08
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Liver	rep_16	2.1e-11
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Liver	rep_16	2.3e-07
Hsd11b2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Liver	rep_16	6.1e-20
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Liver	rep_16	9.5e-13
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Liver	rep_16	1.1e-19
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Liver	rep_16	3.8e-18
Hsd11b2	GOBP_Renal_System_Process	Mouse	Liver	rep_16	4.1e-08
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Liver	rep_16	2.6e-11
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Liver	rep_16	3.3e-15
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Liver	rep_16	8.0e-26
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Liver	rep_16	1.2e-11
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Liver	rep_16	4.8e-07
Hsd11b2	GOBP_Response_To_Food	Mouse	Liver	rep_20	1.3e-12
Hsd11b2	GOBP_Response_To_Corticosteroid	Mouse	Liver	rep_23	7.2e-10
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Intestine	rep_2	2.0e-19
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Intestine	rep_2	1.5e-21
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Lymph	MS-1	3.9e-08
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Lymph	MS-1	2.0e-17
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Lymph	MS-1	4.6e-12
Hsd11b2	GOBP_Positive_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Lymph	MS-1	5.4e-07
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Lymph	MS-1	2.5e-11
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Lymph	MS-1	7.2e-08
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Lymph	MS-1	3.0e-09
Hsd11b2	GOBP_Renal_System_Process	Mouse	Lymph	MS-1	3.1e-12
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Lymph	MS-1	1.9e-07
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Lymph	MS-1	5.5e-09
Hsd11b2	GOBP_Reproduction	Mouse	Lymph	MS-1	1.1e-09
Hsd11b2	GOBP_Response_To_Abiotic_Stimulus	Mouse	Lymph	MS-1	1.5e-07
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lymph	MS-1	3.9e-13
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Lymph	MS-1	1.1e-12
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Lymph	MS-1	7.3e-10
Hsd11b2	GOBP_Response_To_Insulin	Mouse	Lymph	MS-1	1.1e-12
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Lymph	MS-1	8.6e-10
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	1.8e-09
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lymph	MS-1	1.9e-09
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	1.8e-09
Hsd11b2	GOBP_Response_To_Oxygen_Levels	Mouse	Lymph	MS-1	5.9e-07
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Lymph	MS-1	3.9e-14
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Lymph	MS-1	5.0e-11
Hsd11b2	GOBP_Response_To_Steroid_Hormone	Mouse	Lymph	MS-1	3.7e-08
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Lymph	MS-1	5.5e-08
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Lymph	PBS	1.0e-07
Hsd11b2	GOBP_Response_To_Corticosteroid	Mouse	Lymph	PBS	9.1e-07
Hsd11b2	GOBP_Reproduction	Mouse	Lung	rep_1	9.6e-12
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lung	rep_1	2.0e-30
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Lung	rep_1	1.1e-09
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lung	rep_1	5.0e-17
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lung	rep_1	1.2e-19
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	rep_4	1.7e-08
Hsd11b2	GOBP_Positive_Regulation_Of_Blood_Pressure	Mouse	Brain	HP_ad_rep3	1.2e-08
Hsd11b2	GOBP_Glucocorticoid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	7.4e-08
Hsd11b2	GOBP_Reproduction	Mouse	Brain	HP_ad_rep7	7.9e-09
Hsd11b2	GOBP_Response_To_Abiotic_Stimulus	Mouse	Brain	HP_ad_rep7	4.3e-08
Hsd11b2	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	HP_ad_rep7	6.3e-10
Hsd11b2	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	HP_ad_rep7	1.4e-09
Hsd11b2	GOBP_Response_To_Hormone	Mouse	Brain	HP_ad_rep7	4.0e-10
Hsd11b2	GOBP_Response_To_Insulin	Mouse	Brain	HP_ad_rep7	2.9e-07
Hsd11b2	GOBP_Response_To_Lipid	Mouse	Brain	HP_ad_rep7	3.5e-07
Hsd11b2	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	3.5e-10
Hsd11b2	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	HP_ad_rep7	1.4e-09
Hsd11b2	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	4.2e-09
Hsd11b2	GOBP_Response_To_Peptide	Mouse	Brain	HP_ad_rep7	5.1e-11
Hsd11b2	GOBP_Response_To_Peptide_Hormone	Mouse	Brain	HP_ad_rep7	2.9e-11
Hsd11b2	GOBP_Steroid_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	1.4e-10
Hsd11b2	GOBP_Positive_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	HP_ad_rep8	1.8e-16
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_By_Hormone	Mouse	Brain	HP_ad_rep8	6.2e-07
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure_Mediated_By_A_Chemical_Signal	Mouse	Brain	HP_ad_rep8	1.9e-07
Hsd11b2	GOBP_Endocrine_Process	Mouse	Brain	HP_adpolb_rep1	3.9e-13
Hsd11b2	GOBP_Multi_Multicellular_Organism_Process	Mouse	Brain	HP_adpolb_rep1	5.4e-12
Hsd11b2	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.1e-08
Hsd11b2	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.0e-08
Hsd11b2	GOBP_Glucocorticoid_Biosynthetic_Process	Mouse	Brain	HP_adpolb_rep5	3.3e-08
Hsd11b2	GOBP_Response_To_Food	Mouse	Brain	HP_adpolb_rep6	1.0e-07
Hsd11b2	GOBP_Circulatory_System_Process	Mouse	Brain	HP_polb_rep9	5.3e-09
Hsd11b2	GOBP_Lipid_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	1.2e-14
Hsd11b2	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Hsd11b2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	HP_polb_rep9	2.9e-10
Hsd11b2	GOBP_Renal_System_Process	Mouse	Brain	HP_polb_rep9	4.8e-13
Hsd11b2	GOBP_Renal_System_Process_Involved_In_Regulation_Of_Blood_Volume	Mouse	Brain	HP_polb_rep9	7.6e-08
Hsd11b2	GOBP_Response_To_Oxygen_Levels	Mouse	Brain	HP_polb_rep9	4.0e-09
Hsd11b2	GOBP_Steroid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11

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Hsd11b2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hsd11b2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hsd11b2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Hsd11b2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hsd11b2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Hsd11b2	C3887949	Apparent mineralocorticoid excess	16	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Hsd11b2	C0020538	Hypertensive disease	4	CTD_human
Hsd11b2	C0342488	Mineralocorticoid Excess Syndrome, Apparent	2	CTD_human;ORPHANET
Hsd11b2	C0004096	Asthma	1	CTD_human
Hsd11b2	C0011854	Diabetes Mellitus, Insulin-Dependent	1	CTD_human
Hsd11b2	C0023890	Liver Cirrhosis	1	CTD_human
Hsd11b2	C0027051	Myocardial Infarction	1	CTD_human
Hsd11b2	C0027726	Nephrotic Syndrome	1	CTD_human
Hsd11b2	C0032962	Pregnancy Complications	1	CTD_human
Hsd11b2	C0205734	Diabetes, Autoimmune	1	CTD_human
Hsd11b2	C0239946	Fibrosis, Liver	1	CTD_human
Hsd11b2	C0342302	Brittle diabetes	1	CTD_human
Hsd11b2	C3837958	Diabetes Mellitus, Ketosis-Prone	1	CTD_human
Hsd11b2	C4554117	Diabetes Mellitus, Sudden-Onset	1	CTD_human