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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Eif2ak1 (spascer ID:15467)

Gene summary for Eif2ak1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Eif2ak1
	Gene ID	15467
	Gene name	eukaryotic translation initiation factor 2 alpha kinase 1
	Synonyms	HCR\|Hri
	Cytomap	5\|5 G2
	Type of gene	protein-coding
	Description	eukaryotic translation initiation factor 2-alpha kinase 1heme-controlled repressorheme-regulated eukaryotic initiation factor eIF-2-alpha kinaseheme-regulated inhibitorhemin-sensitive initiation factor 2-alpha kinase
	Modification date	20220424
	UniProtAcc	Q9Z2R9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Eif2ak1	GO:0004672	protein kinase activity	21873635	Function

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Spatial pattern events for Eif2ak1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Eif2ak1	Mouse	Brain	S2	34413515	6.71e-08
Eif2ak1	Mouse	Embryo	1F	34210887	2.34e-11
Eif2ak1	Mouse	Embryo	2H	34210887	6.59e-14
Eif2ak1	Mouse	Embryo	rep_4	33188776	8.29e-15
Eif2ak1	Mouse	Brain	rep_1	33469025	5.14e-08
Eif2ak1	Mouse	Brain	rep_3	35027729	1.83e-06
Eif2ak1	Mouse	Testicle	rep_5	34731600	2.80e-14
Eif2ak1	Mouse	Brain	rep_1	35210624	1.55e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Eif2ak1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Spinal cord	CN94_E1	8.2e-06
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Spinal cord	CN94_E1	2.9e-07
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Spinal cord	CN94_E1	2.9e-06
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	1.6e-06
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7bCN01_D2	3.1e-06
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Spinal cord	L7bCN02_E1	7.2e-06
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif2ak1	GOBP_Chemical_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif2ak1	GOBP_Immune_System_Development	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Eif2ak1	GOBP_Integrated_Stress_Response_Signaling	Mouse	Spinal cord	L7CN45_C1	9.9e-06
Eif2ak1	GOBP_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.4e-08
Eif2ak1	GOBP_Iron_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	1.2e-06
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Spinal cord	L7CN45_C1	2.8e-06
Eif2ak1	GOBP_Metal_Ion_Homeostasis	Mouse	Spinal cord	L7CN45_C1	3.0e-08
Eif2ak1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Eif2ak1	GOBP_Phagocytosis	Mouse	Spinal cord	L7CN45_C1	8.6e-06
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.3e-09
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7CN45_C1	7.4e-09
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Spinal cord	L7CN45_C1	3.8e-08
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Spinal cord	L7CN45_C1	6.5e-06
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Spinal cord	L7CN45_C1	7.9e-07
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Spinal cord	L7CN45_C1	9.1e-06
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Eif2ak1	GOBP_Translational_Initiation	Mouse	Spinal cord	L7CN45_C1	1.6e-08
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_E1	2.6e-07
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Spinal cord	L7CN45_E1	1.3e-06
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Spinal cord	L7CN45_E1	9.6e-06
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Spinal cord	L7CN47_C1	6.4e-07
Eif2ak1	GOBP_Defense_Response	Mouse	Spinal cord	L8CN11_C1	3.3e-17
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Spinal cord	L8CN11_C1	3.6e-13
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_19	1.2e-06
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_27	7.2e-05
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_27	4.7e-05
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_27	1.2e-06
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	rep_27	5.2e-05
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Brain	rep_27	7.4e-08
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Brain	rep_41	1.8e-05
Eif2ak1	GOBP_Chemical_Homeostasis	Mouse	Brain	rep_71	8.4e-05
Eif2ak1	GOBP_Ion_Homeostasis	Mouse	Brain	rep_71	9.0e-05
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Brain	rep_71	6.8e-05
Eif2ak1	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	rep_71	4.0e-05
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Brain	rep_71	1.3e-05
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Brain	rep_72	5.7e-05
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Brain	rep_1	4.4e-20
Eif2ak1	GOBP_Phagocytosis	Mouse	Brain	rep_1	1.8e-16
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Brain	rep_1	1.5e-46
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	rep_3	2.5e-86
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Eif2ak1	GOBP_Defense_Response	Mouse	Brain	rep_3	8.7e-77
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-156
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Brain	rep_3	3.9e-134
Eif2ak1	GOBP_Immune_System_Development	Mouse	Brain	rep_3	1.3e-52
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Brain	rep_3	4.1e-53
Eif2ak1	GOBP_Integrated_Stress_Response_Signaling	Mouse	Brain	rep_3	1.4e-157
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Brain	rep_3	1.8e-21
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	rep_3	1.4e-196
Eif2ak1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Mouse	Brain	rep_3	1.6e-104
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	1.9e-161
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	1.1e-139
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_3	5.5e-184
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Brain	rep_3	4.1e-161
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	rep_3	2.1e-69
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	2.9e-187
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	8.5e-206
Eif2ak1	GOBP_Protoporphyrinogen_Ix_Metabolic_Process	Mouse	Brain	rep_3	1.0e-108
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	5.2e-187
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Brain	rep_3	5.1e-104
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Brain	rep_3	3.7e-123
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	rep_3	3.0e-62
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	rep_3	2.2e-188
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	rep_3	8.6e-94
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Brain	rep_3	6.3e-95
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Brain	rep_3	7.5e-118
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Brain	rep_3	1.0e-196
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Brain	rep_3	1.3e-104
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Brain	rep_3	2.1e-84
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	rep_3	2.2e-117
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Brain	rep_3	5.8e-139
Eif2ak1	GOBP_Tetrapyrrole_Metabolic_Process	Mouse	Brain	rep_3	8.3e-184
Eif2ak1	GOBP_Translational_Initiation	Mouse	Brain	rep_3	1.2e-197
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Brain	rep_7	5.3e-14
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Brain	rep_7	2.5e-13
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Brain	rep_7	9.1e-15
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Embryo	rep_6	1.8e-12
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Embryo	rep_6	7.6e-11
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Embryo	rep_6	3.7e-15
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Embryo	rep_14	1.0e-87
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Embryo	rep_14	3.7e-18
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Eif2ak1	GOBP_Integrated_Stress_Response_Signaling	Mouse	Embryo	rep_14	6.3e-63
Eif2ak1	GOBP_Iron_Ion_Homeostasis	Mouse	Embryo	rep_14	2.7e-38
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Embryo	rep_14	2.4e-09
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Embryo	rep_14	1.0e-32
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_14	1.3e-11
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	5.5e-22
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Embryo	rep_14	3.7e-44
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Embryo	rep_14	2.8e-15
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	2.9e-49
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Embryo	rep_14	1.4e-11
Eif2ak1	GOBP_Protoporphyrinogen_Ix_Metabolic_Process	Mouse	Embryo	rep_14	1.7e-45
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	9.9e-25
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Embryo	rep_14	9.4e-42
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Embryo	rep_14	1.2e-21
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Embryo	rep_14	4.3e-51
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Embryo	rep_14	4.3e-70
Eif2ak1	GOBP_Tetrapyrrole_Metabolic_Process	Mouse	Embryo	rep_14	1.6e-59
Eif2ak1	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Embryo	rep_14	2.1e-32
Eif2ak1	GOBP_Translational_Initiation	Mouse	Embryo	rep_14	1.2e-37
Eif2ak1	GOBP_Defense_Response	Mouse	Embryo	rep_1	5.2e-63
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Embryo	rep_1	2.0e-30
Eif2ak1	GOBP_Immune_System_Development	Mouse	Embryo	rep_1	0.0e+00
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Embryo	rep_1	1.1e-20
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Embryo	rep_1	2.4e-139
Eif2ak1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Mouse	Embryo	rep_1	3.5e-170
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Embryo	rep_1	9.4e-07
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Embryo	rep_2	8.0e-13
Eif2ak1	GOBP_Metal_Ion_Homeostasis	Mouse	Embryo	rep_3	2.5e-10
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Embryo	rep_4	1.2e-08
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Embryo	rep_5	1.1e-27
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Embryo	rep_6	9.9e-40
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Kidney	Nep	6.5e-32
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Kidney	Nep	6.5e-32
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Eif2ak1	GOBP_Phagocytosis	Mouse	Kidney	Nep	2.7e-48
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	Nep	4.6e-22
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	Nep	4.6e-22
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Kidney	Nep	1.1e-60
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Kidney	rep_2	2.6e-28
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Eif2ak1	GOBP_Defense_Response	Mouse	Kidney	rep_2	6.8e-127
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Kidney	rep_2	1.1e-42
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Kidney	rep_2	2.2e-10
Eif2ak1	GOBP_Immune_System_Development	Mouse	Kidney	rep_2	4.6e-22
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Kidney	rep_2	8.2e-77
Eif2ak1	GOBP_Integrated_Stress_Response_Signaling	Mouse	Kidney	rep_2	6.3e-08
Eif2ak1	GOBP_Iron_Ion_Homeostasis	Mouse	Kidney	rep_2	8.4e-17
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Kidney	rep_2	1.1e-42
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Kidney	rep_2	4.8e-12
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Kidney	rep_2	1.1e-18
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Kidney	rep_2	7.3e-42
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-139
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	1.0e-19
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-72
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Kidney	rep_2	7.3e-70
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Kidney	rep_2	2.9e-85
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Eif2ak1	GOBP_Phagocytosis	Mouse	Kidney	rep_2	3.4e-104
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-19
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	1.1e-92
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Kidney	rep_2	7.6e-46
Eif2ak1	GOBP_Protoporphyrinogen_Ix_Metabolic_Process	Mouse	Kidney	rep_2	2.6e-11
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	9.8e-137
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Kidney	rep_2	6.4e-80
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Kidney	rep_2	2.3e-15
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Kidney	rep_2	1.3e-41
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Kidney	rep_2	2.2e-44
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Kidney	rep_2	1.8e-44
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Kidney	rep_2	2.8e-119
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Kidney	rep_2	1.7e-95
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Kidney	rep_2	3.5e-71
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Kidney	rep_2	9.9e-45
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Kidney	rep_2	3.3e-65
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Kidney	rep_2	3.8e-52
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Kidney	rep_2	1.3e-11
Eif2ak1	GOBP_Tetrapyrrole_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-18
Eif2ak1	GOBP_Translational_Initiation	Mouse	Kidney	rep_2	1.3e-103
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Liver	CN16-D2	4.1e-07
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Liver	CN16-D2	6.4e-08
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Liver	CN65-C1	5.1e-07
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Liver	CN65-C1	1.6e-08
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Liver	CN73-C1	3.9e-13
Eif2ak1	GOBP_Immune_System_Development	Mouse	Liver	CN73-C1	2.2e-07
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Liver	rep_15	9.6e-23
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Liver	rep_15	5.1e-27
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Liver	rep_15	1.4e-13
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Liver	rep_15	3.7e-07
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Liver	rep_16	2.0e-14
Eif2ak1	GOBP_Defense_Response	Mouse	Liver	rep_16	8.0e-16
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Liver	rep_16	5.8e-15
Eif2ak1	GOBP_Immune_System_Development	Mouse	Liver	rep_16	5.3e-11
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Liver	rep_16	3.5e-14
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Liver	rep_16	1.3e-10
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Liver	rep_16	1.2e-17
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Liver	rep_16	3.3e-13
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Liver	rep_16	4.1e-07
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Liver	rep_16	1.8e-27
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Liver	rep_16	8.0e-26
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Liver	rep_16	9.4e-25
Eif2ak1	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Liver	rep_16	5.7e-28
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-09
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Eif2ak1	GOBP_Chemical_Homeostasis	Mouse	Lymph	MS-1	8.2e-11
Eif2ak1	GOBP_Defense_Response	Mouse	Lymph	MS-1	8.6e-18
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Lymph	MS-1	4.2e-10
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Lymph	MS-1	2.3e-12
Eif2ak1	GOBP_Immune_System_Development	Mouse	Lymph	MS-1	1.2e-13
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Lymph	MS-1	1.2e-12
Eif2ak1	GOBP_Ion_Homeostasis	Mouse	Lymph	MS-1	7.3e-10
Eif2ak1	GOBP_Iron_Ion_Homeostasis	Mouse	Lymph	MS-1	4.1e-12
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Lymph	MS-1	9.5e-18
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Lymph	MS-1	1.4e-28
Eif2ak1	GOBP_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	4.9e-13
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Lymph	MS-1	1.9e-13
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Lymph	MS-1	3.2e-19
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-11
Eif2ak1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Mouse	Lymph	MS-1	5.6e-14
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	6.3e-11
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-11
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Lymph	MS-1	5.3e-10
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Lymph	MS-1	7.1e-07
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Eif2ak1	GOBP_Phagocytosis	Mouse	Lymph	MS-1	9.1e-20
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	7.1e-09
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Lymph	MS-1	3.0e-10
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-08
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Lymph	MS-1	1.6e-14
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Lymph	MS-1	1.2e-12
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Lymph	MS-1	5.6e-12
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Lymph	MS-1	1.9e-12
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Lymph	MS-1	1.4e-12
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Lymph	MS-1	1.1e-10
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Lymph	MS-1	1.2e-07
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Lymph	MS-1	3.5e-09
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Lymph	MS-1	1.1e-12
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Lymph	MS-1	1.7e-10
Eif2ak1	GOBP_Transition_Metal_Ion_Homeostasis	Mouse	Lymph	MS-1	6.0e-11
Eif2ak1	GOBP_Translational_Initiation	Mouse	Lymph	MS-1	7.5e-07
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Lymph	MS-2	8.8e-07
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Lung	rep_1	7.5e-20
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lung	rep_1	4.5e-23
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Lung	rep_1	1.6e-15
Eif2ak1	GOBP_Protoporphyrinogen_Ix_Metabolic_Process	Mouse	Lung	rep_1	7.5e-08
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Lung	rep_1	3.3e-20
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_4	2.4e-10
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Brain	rep_7	5.6e-09
Eif2ak1	GOBP_Porphyrin_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep3	1.3e-07
Eif2ak1	GOBP_Regulation_Of_Hemoglobin_Biosynthetic_Process	Mouse	Brain	HP_ad_rep3	3.8e-10
Eif2ak1	GOBP_Acute_Inflammatory_Response	Mouse	Brain	HP_ad_rep7	4.7e-09
Eif2ak1	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	8.0e-10
Eif2ak1	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Eif2ak1	GOBP_Defense_Response	Mouse	Brain	HP_ad_rep7	5.6e-10
Eif2ak1	GOBP_Immune_System_Development	Mouse	Brain	HP_ad_rep7	8.3e-09
Eif2ak1	GOBP_Myeloid_Cell_Differentiation	Mouse	Brain	HP_ad_rep7	1.2e-09
Eif2ak1	GOBP_Negative_Regulation_Of_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.3e-12
Eif2ak1	GOBP_Negative_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-10
Eif2ak1	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	2.1e-08
Eif2ak1	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.1e-09
Eif2ak1	GOBP_Negative_Regulation_Of_Translational_Initiation	Mouse	Brain	HP_ad_rep7	3.3e-10
Eif2ak1	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Eif2ak1	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	4.4e-10
Eif2ak1	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Eif2ak1	GOBP_Posttranscriptional_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	1.9e-10
Eif2ak1	GOBP_Protein_Autophosphorylation	Mouse	Brain	HP_ad_rep7	5.6e-08
Eif2ak1	GOBP_Protoporphyrinogen_Ix_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.6e-11
Eif2ak1	GOBP_Regulation_Of_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-07
Eif2ak1	GOBP_Regulation_Of_Phosphorus_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.7e-08
Eif2ak1	GOBP_Regulation_Of_Protein_Modification_Process	Mouse	Brain	HP_ad_rep7	1.1e-07
Eif2ak1	GOBP_Regulation_Of_Protein_Phosphorylation	Mouse	Brain	HP_ad_rep7	4.0e-09
Eif2ak1	GOBP_Regulation_Of_Response_To_Stress	Mouse	Brain	HP_ad_rep7	5.4e-09
Eif2ak1	GOBP_Regulation_Of_Translation_In_Response_To_Stress	Mouse	Brain	HP_ad_rep7	1.0e-15
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation	Mouse	Brain	HP_ad_rep7	3.8e-08
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_By_Eif2_Alpha_Phosphorylation	Mouse	Brain	HP_ad_rep7	5.4e-12
Eif2ak1	GOBP_Regulation_Of_Translational_Initiation_In_Response_To_Stress	Mouse	Brain	HP_ad_rep7	3.6e-13
Eif2ak1	GOBP_Response_To_Extracellular_Stimulus	Mouse	Brain	HP_ad_rep7	1.4e-09
Eif2ak1	GOBP_Response_To_Starvation	Mouse	Brain	HP_ad_rep7	4.4e-12
Eif2ak1	GOBP_Translational_Initiation	Mouse	Brain	HP_ad_rep7	6.9e-08
Eif2ak1	GOBP_Hemoglobin_Biosynthetic_Process	Mouse	Brain	HP_ad_rep8	7.1e-07
Eif2ak1	GOBP_Integrated_Stress_Response_Signaling	Mouse	Brain	HP_ad_rep8	5.8e-09
Eif2ak1	GOBP_Tetrapyrrole_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	8.6e-14
Eif2ak1	GOBP_Chemical_Homeostasis	Mouse	Brain	HP_polb_rep9	9.6e-10
Eif2ak1	GOBP_Hemoglobin_Metabolic_Process	Mouse	Brain	HP_polb_rep9	3.4e-20
Eif2ak1	GOBP_Homeostatic_Process	Mouse	Brain	HP_polb_rep9	6.4e-11
Eif2ak1	GOBP_Inflammatory_Response	Mouse	Brain	HP_polb_rep9	2.0e-10
Eif2ak1	GOBP_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.5e-08
Eif2ak1	GOBP_Leukocyte_Differentiation	Mouse	Brain	HP_polb_rep9	2.1e-12
Eif2ak1	GOBP_Macrophage_Differentiation	Mouse	Brain	HP_polb_rep9	1.2e-15
Eif2ak1	GOBP_Metal_Ion_Homeostasis	Mouse	Brain	HP_polb_rep9	1.2e-07
Eif2ak1	GOBP_Myeloid_Leukocyte_Differentiation	Mouse	Brain	HP_polb_rep9	5.4e-12
Eif2ak1	GOBP_Negative_Regulation_Of_Cell_Population_Proliferation	Mouse	Brain	HP_polb_rep9	2.8e-10
Eif2ak1	GOBP_Phagocytosis	Mouse	Brain	HP_polb_rep9	2.5e-08
Eif2ak1	GOBP_Regulation_Of_Cellular_Response_To_Stress	Mouse	Brain	HP_polb_rep9	1.2e-11

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Eif2ak1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Eif2ak1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Eif2ak1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Eif2ak1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Eif2ak1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Eif2ak1	C0002878	Anemia, Hemolytic	1	CTD_human
Eif2ak1	C0002879	Anemia, Hemolytic, Acquired	1	CTD_human
Eif2ak1	C0002889	Anemia, Microangiopathic	1	CTD_human
Eif2ak1	C0019193	Hepatitis, Toxic	1	CTD_human
Eif2ak1	C0035222	Respiratory Distress Syndrome, Adult	1	CTD_human
Eif2ak1	C0038002	Splenomegaly	1	CTD_human
Eif2ak1	C0221021	Microangiopathic hemolytic anemia	1	CTD_human
Eif2ak1	C0400966	Non-alcoholic Fatty Liver Disease	1	CTD_human
Eif2ak1	C0860207	Drug-Induced Liver Disease	1	CTD_human
Eif2ak1	C1262760	Hepatitis, Drug-Induced	1	CTD_human
Eif2ak1	C3241937	Nonalcoholic Steatohepatitis	1	CTD_human
Eif2ak1	C3658290	Drug-Induced Acute Liver Injury	1	CTD_human
Eif2ak1	C4277682	Chemical and Drug Induced Liver Injury	1	CTD_human
Eif2ak1	C4279912	Chemically-Induced Liver Toxicity	1	CTD_human