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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Hoxc9 (spascer ID:15427)

Gene summary for Hoxc9

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Hoxc9
	Gene ID	15427
	Gene name	homeobox C9
	Synonyms	Hox-3.2
	Cytomap	15 F3\|15 58.04 cM
	Type of gene	protein-coding
	Description	homeobox protein Hox-C9homeo box C9homeobox protein Hox-3.2
	Modification date	20220424
	UniProtAcc	P09633

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Hoxc9	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	21873635	Function
Hoxc9	GO:0003700	DNA-binding transcription factor activity	21873635	Function
Hoxc9	GO:0005634	nucleus	21873635	Component
Hoxc9	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process
Hoxc9	GO:0009952	anterior/posterior pattern specification	21873635	Process
Hoxc9	GO:0009954	proximal/distal pattern formation	21873635	Process
Hoxc9	GO:0048704	embryonic skeletal system morphogenesis	21873635	Process

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Spatial pattern events for Hoxc9

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Hoxc9	Mouse	Embryo	rep_4	33188776	5.08e-15
Hoxc9	Mouse	Embryo	rep_12	33188776	4.84e-15
Hoxc9	Mouse	Embryo	rep_13	33188776	4.49e-15
Hoxc9	Mouse	Embryo	rep_1	34489600	3.74e-16
Hoxc9	Mouse	Embryo	rep_2	34489600	4.14e-16
Hoxc9	Mouse	Embryo	rep_3	34489600	4.04e-16
Hoxc9	Mouse	Embryo	rep_4	34489600	3.67e-16
Hoxc9	Mouse	Embryo	rep_5	34489600	4.08e-16
Hoxc9	Mouse	Embryo	rep_6	34489600	7.05e-16
Hoxc9	Mouse	Kidney	Sham	34003797	3.41e-09
Hoxc9	Mouse	Kidney	rep_1	33976190	2.36e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_Sham_H&E
Kidney_rep_1_H&E

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Spatial pattern pathway has Hoxc9 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	7.7e-07
Hoxc9	GOBP_Regionalization	Mouse	Spinal cord	CN94_E1	7.3e-06
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Spinal cord	CN94_E1	5.6e-06
Hoxc9	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
Hoxc9	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Spinal cord	L7CN47_C1	3.7e-07
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Spinal cord	L8CN17_E1	2.7e-06
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	rep_27	3.1e-05
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_27	3.2e-09
Hoxc9	GOBP_Regionalization	Mouse	Brain	rep_27	3.9e-08
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_71	2.6e-07
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Brain	rep_74	7.7e-10
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	rep_3	1.2e-140
Hoxc9	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Hoxc9	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_3	4.3e-190
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-168
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Brain	rep_3	1.0e-111
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Brain	rep_3	1.2e-119
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_3	1.6e-118
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Brain	rep_3	1.1e-13
Hoxc9	GOBP_Regionalization	Mouse	Brain	rep_3	1.3e-180
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Brain	rep_3	3.3e-190
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	rep_3	7.3e-51
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Embryo	rep_6	1.5e-09
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_6	3.8e-12
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Embryo	rep_14	2.2e-13
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Embryo	rep_14	5.5e-53
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_14	2.3e-45
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Embryo	rep_14	9.0e-18
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Embryo	rep_2	8.6e-166
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Embryo	rep_2	0.0e+00
Hoxc9	GOBP_Regionalization	Mouse	Embryo	rep_2	5.4e-84
Hoxc9	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Embryo	rep_3	4.4e-129
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_3	0.0e+00
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Embryo	rep_3	2.8e-168
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Embryo	rep_3	0.0e+00
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Embryo	rep_6	3.1e-59
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Kidney	rep_2	3.0e-23
Hoxc9	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
Hoxc9	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Kidney	rep_2	1.3e-60
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.0e-55
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Kidney	rep_2	2.0e-38
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Kidney	rep_2	1.6e-37
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Kidney	rep_2	2.3e-36
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Kidney	rep_2	5.2e-14
Hoxc9	GOBP_Regionalization	Mouse	Kidney	rep_2	2.1e-25
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Kidney	rep_2	7.5e-46
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Kidney	rep_2	1.2e-20
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Liver	CN16-D2	2.4e-09
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Liver	CN73-C1	9.4e-07
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Liver	rep_15	1.5e-24
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Liver	rep_15	2.2e-34
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Liver	rep_16	3.6e-20
Hoxc9	GOBP_Regionalization	Mouse	Liver	rep_16	1.2e-11
Hoxc9	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Hoxc9	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
Hoxc9	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Lymph	MS-1	1.1e-11
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Lymph	MS-1	1.4e-11
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Lymph	MS-1	5.9e-22
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Lymph	MS-1	7.9e-14
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Lymph	MS-1	3.9e-12
Hoxc9	GOBP_Proximal_Distal_Pattern_Formation	Mouse	Lymph	MS-1	3.3e-09
Hoxc9	GOBP_Regionalization	Mouse	Lymph	MS-1	2.7e-12
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Lymph	MS-1	2.6e-12
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Lymph	MS-1	8.7e-13
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Lung	rep_1	4.0e-16
Hoxc9	GOBP_Regionalization	Mouse	Brain	rep_4	6.3e-07
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_7	7.0e-07
Hoxc9	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_7	2.6e-14
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_7	1.0e-12
Hoxc9	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
Hoxc9	GOBP_Pattern_Specification_Process	Mouse	Brain	HP_ad_rep7	2.1e-10
Hoxc9	GOBP_Regionalization	Mouse	Brain	HP_ad_rep7	2.8e-09
Hoxc9	GOBP_Skeletal_System_Development	Mouse	Brain	HP_ad_rep7	3.7e-09
Hoxc9	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	HP_adpolb_rep1	3.0e-08
Hoxc9	GOBP_Embryonic_Skeletal_System_Development	Mouse	Brain	HP_adpolb_rep1	6.0e-10
Hoxc9	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Hoxc9	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Hoxc9	GOBP_Embryonic_Organ_Development	Mouse	Brain	HP_polb_rep9	9.6e-11
Hoxc9	GOBP_Embryonic_Skeletal_System_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.5e-15
Hoxc9	GOBP_Skeletal_System_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.1e-07

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Hoxc9 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Hoxc9 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Hoxc9 envolved

Transcription factor analysis using single cell data.

TF	Tissue	Group	Cell types	Target genes	Rss score
Hoxc9	Kidney	control	Unknown	Hoxc8,Cdx4,Cdx2, etc.	0.395
Hoxc9	Kidney	control	Mesonephric tubule	Hoxc8,Cdx4,Cdx2, etc.	0.324
Hoxc9	Kidney	control	Nephric duct	Hoxc8,Cdx4,Cdx2, etc.	0.338
Hoxc9	Kidney	control	Intermediate mesoderm	Hoxc8,Cdx4,Cdx2, etc.	0.393
Hoxc9	Kidney	disease	Intermediate mesoderm	Hoxc8,Hoxa9,Hoxc10, etc.	0.285
Hoxc9	Kidney	disease	Nephric duct	Hoxc8,Hoxa9,Hoxc10, etc.	0.348
Hoxc9	Kidney	disease	Taibub	Hoxc8,Hoxa9,Hoxc10, etc.	0.511
Hoxc9	Kidney	disease	Mesonephric tubule	Hoxc8,Hoxa9,Hoxc10, etc.	0.321

Motif information.

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Related Drugs for Hoxc9

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Hoxc9

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source