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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pfdn6 (spascer ID:14976)

Gene summary for Pfdn6

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pfdn6
	Gene ID	14976
	Gene name	prefoldin subunit 6
	Synonyms	H-2Ke2\|H2-Ke2\|Ke-2
	Cytomap	17 B1\|17 17.98 cM
	Type of gene	protein-coding
	Description	prefoldin subunit 6H2-K region expressed gene 2protein Ke2
	Modification date	20220424
	UniProtAcc	Q03958

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pfdn6	GO:0005737	cytoplasm	21873635	Component
Pfdn6	GO:0006457	protein folding	21873635	Process
Pfdn6	GO:0016272	prefoldin complex	21873635	Component
Pfdn6	GO:0051087	chaperone binding	21873635	Function
Pfdn6	GO:0051131	chaperone-mediated protein complex assembly	21873635	Process

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Spatial pattern events for Pfdn6

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pfdn6	Mouse	Brain	S1	34413515	2.33e-09
Pfdn6	Mouse	Brain	S2	34413515	2.21e-06
Pfdn6	Mouse	Brain	S3	34413515	2.29e-06
Pfdn6	Mouse	Brain	S4	34413515	2.93e-08
Pfdn6	Mouse	Brain	rep_1	35141374	1.68e-11
Pfdn6	Mouse	Brain	rep_2	35141374	5.75e-15
Pfdn6	Mouse	Brain	rep_3	35141374	7.44e-08
Pfdn6	Mouse	Brain	rep_4	35141374	1.41e-09
Pfdn6	Mouse	Brain	rep_5	35141374	3.85e-06
Pfdn6	Mouse	Kidney	CLP	34003797	1.99e-10
Pfdn6	Mouse	Kidney	Sham	34003797	7.24e-11
Pfdn6	Mouse	Kidney	rep_1	34853151	4.13e-15
Pfdn6	Mouse	Brain	rep_1	33469025	1.74e-09
Pfdn6	Mouse	Brain	rep_3	35027729	8.79e-07
Pfdn6	Mouse	Brain	rep_5	35027729	7.45e-11
Pfdn6	Mouse	Testicle	rep_4	34731600	2.52e-14
Pfdn6	Mouse	Lymph	A1	0	3.29e-15
Pfdn6	Mouse	Lymph	B1	0	1.36e-08
Pfdn6	Mouse	Brain	rep_1	35210624	2.39e-06
Pfdn6	Mouse	Brain	rep_2	35210624	1.30e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Pfdn6 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Spinal cord	CN94_E1	7.0e-06
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_27	1.2e-06
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Brain	rep_75	7.6e-07
Pfdn6	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Brain	rep_1	3.5e-07
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Brain	rep_3	1.8e-109
Pfdn6	GOBP_Chaperone_Mediated_Protein_Complex_Assembly	Mouse	Brain	rep_3	1.1e-123
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Brain	rep_3	3.7e-28
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	rep_3	4.4e-113
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_3	5.5e-184
Pfdn6	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	1.0e-83
Pfdn6	GOBP_Protein_Folding	Mouse	Brain	rep_3	5.7e-177
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Brain	rep_3	2.8e-89
Pfdn6	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	rep_3	6.7e-78
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Embryo	rep_14	1.8e-80
Pfdn6	GOBP_Chaperone_Mediated_Protein_Complex_Assembly	Mouse	Embryo	rep_14	9.9e-19
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Embryo	rep_14	1.9e-67
Pfdn6	GOBP_Protein_Folding	Mouse	Embryo	rep_14	3.2e-12
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Embryo	rep_14	5.8e-60
Pfdn6	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_1	1.3e-102
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Embryo	rep_3	2.7e-07
Pfdn6	GOBP_Supramolecular_Fiber_Organization	Mouse	Embryo	rep_3	0.0e+00
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Kidney	rep_2	4.0e-111
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Kidney	rep_2	1.6e-75
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Kidney	rep_2	8.7e-59
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-72
Pfdn6	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	3.6e-76
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Kidney	rep_2	2.4e-82
Pfdn6	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.1e-54
Pfdn6	GOBP_Supramolecular_Fiber_Organization	Mouse	Kidney	rep_2	9.5e-65
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Liver	CN16-D1	6.2e-07
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Liver	CN16-D2	1.1e-07
Pfdn6	GOBP_Chaperone_Mediated_Protein_Complex_Assembly	Mouse	Liver	CN16-D2	7.9e-07
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Liver	rep_16	5.5e-09
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Liver	rep_16	5.1e-08
Pfdn6	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Liver	rep_16	1.3e-07
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Liver	rep_16	5.9e-08
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Lymph	MS-1	7.2e-08
Pfdn6	GOBP_Chaperone_Mediated_Protein_Complex_Assembly	Mouse	Lymph	MS-1	4.8e-09
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Lymph	MS-1	8.2e-08
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Lymph	MS-1	3.7e-11
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-11
Pfdn6	GOBP_Negative_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	3.9e-11
Pfdn6	GOBP_Protein_Folding	Mouse	Lymph	MS-1	1.6e-14
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Lymph	MS-1	3.2e-08
Pfdn6	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	4.3e-11
Pfdn6	GOBP_Supramolecular_Fiber_Organization	Mouse	Lymph	MS-1	1.5e-12
Pfdn6	GOBP_Negative_Regulation_Of_Cellular_Component_Organization	Mouse	Brain	HP_ad_rep7	2.6e-08
Pfdn6	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.1e-09
Pfdn6	GOBP_Supramolecular_Fiber_Organization	Mouse	Brain	HP_ad_rep7	5.2e-07
Pfdn6	GOBP_Amyloid_Fibril_Formation	Mouse	Brain	HP_adpolb_rep1	1.7e-07
Pfdn6	GOBP_Chaperone_Mediated_Protein_Complex_Assembly	Mouse	Brain	HP_adpolb_rep1	6.7e-07
Pfdn6	GOBP_Negative_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Brain	HP_adpolb_rep1	7.8e-09
Pfdn6	GOBP_Protein_Folding	Mouse	Brain	HP_adpolb_rep1	5.2e-07
Pfdn6	GOBP_Regulation_Of_Amyloid_Fibril_Formation	Mouse	Brain	HP_adpolb_rep1	4.9e-14

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Pfdn6 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pfdn6 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pfdn6 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pfdn6

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pfdn6

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source