Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Cfb (spascer ID:14962)

Gene summary for Cfb

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Cfb
	Gene ID	14962
	Gene name	complement factor B
	Synonyms	AI195813\|AI255840\|Bf\|C2\|Fb\|H2-Bf
	Cytomap	17 B1\|17 18.41 cM
	Type of gene	protein-coding
	Description	complement factor BC3/C5 convertaseFactor Balternative-complement pathway C3/C5 convertasecomplement component 2 (within H-2S)histocompatibility 2, complement component factor Bproperdin
	Modification date	20220503
	UniProtAcc	P04186

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

Top

Spatial pattern events for Cfb

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Cfb	Mouse	Brain	S1	34413515	2.07e-15
Cfb	Mouse	Brain	S2	34413515	2.85e-15
Cfb	Mouse	Brain	S6	34413515	1.46e-15
Cfb	Mouse	Kidney	CLP	34003797	2.19e-15
Cfb	Mouse	Kidney	IRI	34003797	2.29e-15
Cfb	Mouse	Kidney	Sham	34003797	2.58e-15
Cfb	Mouse	Kidney	rep_1	34853151	2.42e-15
Cfb	Mouse	Kidney	rep_2	34853151	3.38e-15
Cfb	Mouse	Kidney	rep_3	34853151	2.94e-15
Cfb	Mouse	Kidney	rep_4	34853151	4.07e-15
Cfb	Mouse	Kidney	rep_5	34853151	3.18e-15
Cfb	Mouse	Liver	rep_14	35021063	1.81e-09
Cfb	Mouse	Liver	rep_18	35021063	7.87e-06
Cfb	Mouse	Liver	rep_20	35021063	3.55e-06
Cfb	Mouse	Intestine	rep_1	35149721	1.97e-06
Cfb	Mouse	Intestine	rep_2	35149721	3.44e-15
Cfb	Mouse	Intestine	rep_3	35149721	3.25e-15
Cfb	Mouse	Lymph	MS-1	0	6.88e-14
Cfb	Mouse	Lymph	A1	0	3.29e-15
Cfb	Mouse	Lymph	B1	0	3.66e-15
Cfb	Mouse	Lung	rep_1	35290801	4.52e-15
Cfb	Mouse	Lung	rep_2	35290801	7.23e-15
Cfb	Mouse	Lung	rep_3	35290801	5.26e-15
Cfb	Mouse	Lung	rep_4	35290801	3.04e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_2_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Liver_rep_14_H&E
Liver_rep_18_H&E
Liver_rep_20_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

Top

Spatial pattern pathway has Cfb envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	CN94_E1	6.6e-06
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Spinal cord	CN94_E1	1.1e-07
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Spinal cord	CN94_E1	2.6e-08
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Spinal cord	L7CN44_C1	1.1e-08
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	7.8e-08
Cfb	GOBP_Humoral_Immune_Response	Mouse	Spinal cord	L7CN45_C1	1.3e-07
Cfb	GOBP_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	3.1e-07
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	8.7e-09
Cfb	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Spinal cord	L7CN45_C1	6.9e-07
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Spinal cord	L7CN97_E2	7.9e-07
Cfb	GOBP_Innate_Immune_Response	Mouse	Spinal cord	L7CN97_E2	2.7e-06
Cfb	GOBP_Complement_Activation	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Cfb	GOBP_Defense_Response	Mouse	Spinal cord	L8CN11_C1	3.3e-17
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Brain	rep_19	3.6e-05
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Brain	rep_27	4.3e-09
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_27	7.5e-06
Cfb	GOBP_Humoral_Immune_Response	Mouse	Brain	rep_41	1.6e-05
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Brain	rep_1	1.7e-16
Cfb	GOBP_Immune_Effector_Process	Mouse	Brain	rep_1	1.5e-12
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Brain	rep_3	6.5e-108
Cfb	GOBP_Defense_Response	Mouse	Brain	rep_3	8.7e-77
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	rep_3	6.0e-105
Cfb	GOBP_Humoral_Immune_Response	Mouse	Brain	rep_3	2.5e-108
Cfb	GOBP_Innate_Immune_Response	Mouse	Brain	rep_3	7.5e-97
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	7.6e-125
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.9e-97
Cfb	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Brain	rep_3	4.5e-106
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Brain	rep_3	3.1e-79
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Brain	rep_3	8.0e-182
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	rep_3	1.1e-86
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	rep_3	6.4e-111
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Embryo	rep_7	3.6e-07
Cfb	GOBP_Complement_Activation	Mouse	Embryo	rep_14	4.8e-55
Cfb	GOBP_Humoral_Immune_Response	Mouse	Embryo	rep_14	6.4e-58
Cfb	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_14	3.3e-15
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Embryo	rep_14	9.6e-07
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Embryo	rep_14	4.4e-50
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Embryo	rep_14	1.1e-54
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Embryo	rep_14	1.0e-29
Cfb	GOBP_Defense_Response	Mouse	Embryo	rep_1	5.2e-63
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	7.3e-23
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Embryo	rep_1	9.5e-143
Cfb	GOBP_Immune_Effector_Process	Mouse	Embryo	rep_2	1.7e-23
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Embryo	rep_3	2.6e-164
Cfb	GOBP_Innate_Immune_Response	Mouse	Embryo	rep_3	2.0e-259
Cfb	GOBP_Complement_Activation	Mouse	Kidney	IRI	6.7e-07
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Kidney	IRI	1.3e-81
Cfb	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Kidney	rep_1	7.7e-08
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Kidney	rep_2	5.4e-134
Cfb	GOBP_Complement_Activation	Mouse	Kidney	rep_2	1.1e-201
Cfb	GOBP_Defense_Response	Mouse	Kidney	rep_2	6.8e-127
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Kidney	rep_2	2.3e-129
Cfb	GOBP_Humoral_Immune_Response	Mouse	Kidney	rep_2	7.8e-96
Cfb	GOBP_Immune_Effector_Process	Mouse	Kidney	rep_2	3.4e-107
Cfb	GOBP_Innate_Immune_Response	Mouse	Kidney	rep_2	3.1e-117
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	8.3e-94
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	1.2e-85
Cfb	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Kidney	rep_2	1.1e-42
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Kidney	rep_2	7.0e-98
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Kidney	rep_2	1.3e-91
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Kidney	rep_2	2.5e-84
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Liver	CN16-E1	8.0e-10
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Liver	CN65-D1	3.2e-07
Cfb	GOBP_Complement_Activation	Mouse	Liver	CN73-C1	3.2e-10
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Liver	rep_16	5.6e-12
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Liver	rep_16	1.6e-08
Cfb	GOBP_Defense_Response	Mouse	Liver	rep_16	8.0e-16
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Liver	rep_16	1.8e-13
Cfb	GOBP_Humoral_Immune_Response	Mouse	Liver	rep_16	6.6e-21
Cfb	GOBP_Innate_Immune_Response	Mouse	Liver	rep_16	5.5e-09
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.3e-11
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Liver	rep_16	1.4e-09
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Liver	rep_16	2.0e-24
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Liver	rep_16	2.5e-16
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-23
Cfb	GOBP_Complement_Activation	Mouse	Lymph	MS-1	9.7e-19
Cfb	GOBP_Defense_Response	Mouse	Lymph	MS-1	8.6e-18
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Lymph	MS-1	6.7e-20
Cfb	GOBP_Humoral_Immune_Response	Mouse	Lymph	MS-1	3.4e-24
Cfb	GOBP_Immune_Effector_Process	Mouse	Lymph	MS-1	1.6e-18
Cfb	GOBP_Innate_Immune_Response	Mouse	Lymph	MS-1	6.7e-20
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	1.0e-21
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	1.6e-18
Cfb	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Lymph	MS-1	5.6e-18
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Lymph	MS-1	2.5e-18
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Lymph	MS-1	2.3e-21
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Lymph	MS-1	2.2e-14
Cfb	GOBP_Immune_Effector_Process	Mouse	Brain	rep_4	7.2e-15
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Brain	rep_4	3.7e-10
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Brain	rep_7	1.4e-60
Cfb	GOBP_Complement_Activation	Mouse	Brain	HP_ad_rep7	1.9e-07
Cfb	GOBP_Complement_Activation_Alternative_Pathway	Mouse	Brain	HP_ad_rep7	1.8e-12
Cfb	GOBP_Defense_Response	Mouse	Brain	HP_ad_rep7	5.6e-10
Cfb	GOBP_Positive_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	4.6e-07
Cfb	GOBP_Positive_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	5.5e-07
Cfb	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Cfb	GOBP_Regulation_Of_Immune_Effector_Process	Mouse	Brain	HP_ad_rep7	1.6e-08
Cfb	GOBP_Regulation_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	2.1e-11
Cfb	GOBP_Regulation_Of_Immune_System_Process	Mouse	Brain	HP_ad_rep7	1.8e-09
Cfb	GOBP_Regulation_Of_Complement_Activation	Mouse	Brain	HP_ad_rep8	9.3e-08
Cfb	GOBP_Humoral_Immune_Response	Mouse	Brain	HP_adpolb_rep1	2.0e-13
Cfb	GOBP_Regulation_Of_Humoral_Immune_Response	Mouse	Brain	HP_adpolb_rep1	1.6e-07
Cfb	GOBP_Activation_Of_Immune_Response	Mouse	Brain	HP_polb_rep9	2.1e-07
Cfb	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	HP_polb_rep9	2.1e-11
Cfb	GOBP_Immune_Effector_Process	Mouse	Brain	HP_polb_rep9	1.0e-08
Cfb	GOBP_Innate_Immune_Response	Mouse	Brain	HP_polb_rep9	3.9e-11

Top

Cfb function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Cfb function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Cfb envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Cfb

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Cfb

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source