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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: H13 (spascer ID:14950)

Gene summary for H13

Gene summary

Gene information
	Species	Mouse
	Gene symbol	H13
	Gene ID	14950
	Gene name	histocompatibility 13
	Synonyms	1200006O09Rik\|4930443L17Rik\|5031424B04Rik\|AV020344\|H-13\|Hm13\|PSL3\|Spp
	Cytomap	2 H1\|2 75.41 cM
	Type of gene	protein-coding
	Description	minor histocompatibility antigen H13presenilin-like aspartyl proteasepresenilin-like protein 3signal peptide peptidase beta
	Modification date	20220424
	UniProtAcc	Q9D8V0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
H13	GO:0006465	signal peptide processing	21873635	Process
H13	GO:0033619	membrane protein proteolysis	21873635	Process
H13	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving	21873635	Function
H13	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane	21873635	Component
H13	GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	21873635	Component

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Spatial pattern events for H13

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
H13	Mouse	Brain	S1	34413515	3.24e-08
H13	Mouse	Brain	S2	34413515	9.95e-13
H13	Mouse	Brain	S3	34413515	1.64e-15
H13	Mouse	Brain	S4	34413515	1.37e-15
H13	Mouse	Brain	S6	34413515	1.46e-15
H13	Mouse	Brain	S7	34413515	1.55e-15
H13	Mouse	Brain	rep_1	35141374	2.02e-15
H13	Mouse	Brain	rep_2	35141374	1.19e-12
H13	Mouse	Brain	rep_3	35141374	1.64e-15
H13	Mouse	Brain	rep_4	35141374	1.57e-15
H13	Mouse	Brain	rep_5	35141374	1.47e-15
H13	Mouse	Brain	rep_6	35141374	6.16e-13
H13	Mouse	Embryo	rep_13	33188776	5.58e-06
H13	Mouse	Kidney	IRI	34003797	3.92e-15
H13	Mouse	Kidney	rep_2	34853151	1.01e-08
H13	Mouse	Kidney	rep_4	34853151	1.75e-06
H13	Mouse	Brain	rep_1	33469025	5.65e-08
H13	Mouse	Brain	rep_1	35027729	1.66e-15
H13	Mouse	Brain	rep_2	35027729	2.83e-15
H13	Mouse	Brain	rep_3	35027729	1.32e-15
H13	Mouse	Brain	rep_4	35027729	7.81e-10
H13	Mouse	Brain	rep_5	35027729	1.46e-15
H13	Mouse	Intestine	rep_2	35149721	2.15e-11
H13	Mouse	Intestine	rep_4	35149721	9.73e-11
H13	Mouse	Lymph	A1	0	3.29e-15
H13	Mouse	Lymph	B1	0	3.66e-15
H13	Mouse	Lung	rep_1	35290801	1.94e-10
H13	Mouse	Lung	rep_2	35290801	9.51e-14
H13	Mouse	Lung	rep_3	35290801	7.35e-08
H13	Mouse	Lung	rep_4	35290801	5.40e-15
H13	Mouse	Brain	rep_1	35210624	1.74e-15
H13	Mouse	Brain	rep_2	35210624	1.74e-15
H13	Mouse	Brain	rep_3	35210624	3.27e-15
H13	Mouse	Brain	rep_5	35210624	3.10e-06
H13	Mouse	Brain	rep_7	35210624	1.25e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_IRI_H&E
Kidney_rep_2_H&E
Kidney_rep_4_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has H13 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Spinal cord	CN94_E1	3.8e-07
H13	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	5.6e-06
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
H13	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Spinal cord	L7CN45_C1	3.9e-07
H13	GOBP_Erad_Pathway	Mouse	Spinal cord	L7CN45_C1	1.3e-06
H13	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
H13	GOBP_Intracellular_Protein_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
H13	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	7.5e-06
H13	GOBP_Membrane_Protein_Proteolysis	Mouse	Spinal cord	L7CN45_C1	4.2e-06
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
H13	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
H13	GOBP_Protein_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
H13	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
H13	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Spinal cord	L7CN45_C1	2.7e-07
H13	GOBP_Signal_Peptide_Processing	Mouse	Spinal cord	L7CN45_C1	4.9e-08
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Brain	rep_41	3.6e-06
H13	GOBP_Signal_Peptide_Processing	Mouse	Brain	rep_41	1.4e-08
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	rep_1	1.0e-08
H13	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	rep_1	1.0e-19
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
H13	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-162
H13	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Brain	rep_3	3.0e-193
H13	GOBP_Erad_Pathway	Mouse	Brain	rep_3	8.8e-162
H13	GOBP_Intracellular_Protein_Transport	Mouse	Brain	rep_3	2.7e-132
H13	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	rep_3	1.7e-159
H13	GOBP_Membrane_Protein_Proteolysis	Mouse	Brain	rep_3	1.2e-09
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
H13	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
H13	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Brain	rep_3	2.9e-169
H13	GOBP_Protein_Catabolic_Process	Mouse	Brain	rep_3	3.0e-174
H13	GOBP_Protein_Exit_From_Endoplasmic_Reticulum	Mouse	Brain	rep_3	3.5e-185
H13	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
H13	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
H13	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	rep_3	6.3e-133
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	rep_3	2.5e-82
H13	GOBP_Signal_Peptide_Processing	Mouse	Brain	rep_3	3.0e-189
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Embryo	rep_14	2.1e-77
H13	GOBP_Erad_Pathway	Mouse	Embryo	rep_14	1.8e-28
H13	GOBP_Membrane_Protein_Proteolysis	Mouse	Embryo	rep_14	2.8e-54
H13	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
H13	GOBP_Protein_Exit_From_Endoplasmic_Reticulum	Mouse	Embryo	rep_14	5.1e-24
H13	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
H13	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
H13	GOBP_Signal_Peptide_Processing	Mouse	Embryo	rep_14	3.4e-49
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
H13	GOBP_Protein_Catabolic_Process	Mouse	Embryo	rep_1	4.1e-19
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
H13	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Embryo	rep_3	0.0e+00
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Embryo	rep_3	1.8e-13
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
H13	GOBP_Intracellular_Protein_Transport	Mouse	Embryo	rep_4	1.1e-39
H13	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
H13	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
H13	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
H13	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
H13	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Kidney	rep_2	3.2e-21
H13	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Kidney	rep_2	9.8e-28
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Kidney	rep_2	6.2e-29
H13	GOBP_Erad_Pathway	Mouse	Kidney	rep_2	2.9e-66
H13	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Kidney	rep_2	7.1e-20
H13	GOBP_Intracellular_Protein_Transport	Mouse	Kidney	rep_2	7.5e-54
H13	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Kidney	rep_2	7.0e-40
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
H13	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
H13	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Kidney	rep_2	5.3e-33
H13	GOBP_Protein_Catabolic_Process	Mouse	Kidney	rep_2	7.3e-30
H13	GOBP_Protein_Exit_From_Endoplasmic_Reticulum	Mouse	Kidney	rep_2	7.2e-49
H13	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
H13	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Kidney	rep_2	1.2e-89
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	1.0e-56
H13	GOBP_Signal_Peptide_Processing	Mouse	Kidney	rep_2	8.7e-112
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Liver	CN16-D2	8.6e-07
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	CN16-D2	6.4e-07
H13	GOBP_Signal_Peptide_Processing	Mouse	Liver	CN16-D2	6.5e-08
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Liver	rep_16	7.6e-16
H13	GOBP_Membrane_Protein_Proteolysis	Mouse	Liver	rep_16	3.8e-08
H13	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
H13	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
H13	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
H13	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Lymph	MS-1	4.0e-11
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Lymph	MS-1	5.7e-07
H13	GOBP_Erad_Pathway	Mouse	Lymph	MS-1	8.7e-14
H13	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Lymph	MS-1	5.3e-13
H13	GOBP_Intracellular_Protein_Transport	Mouse	Lymph	MS-1	3.0e-17
H13	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
H13	GOBP_Membrane_Protein_Proteolysis	Mouse	Lymph	MS-1	9.4e-09
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
H13	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
H13	GOBP_Protein_Catabolic_Process	Mouse	Lymph	MS-1	1.1e-11
H13	GOBP_Protein_Exit_From_Endoplasmic_Reticulum	Mouse	Lymph	MS-1	5.9e-09
H13	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
H13	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Lymph	MS-1	1.7e-11
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	1.8e-09
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Lung	rep_1	2.0e-21
H13	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
H13	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
H13	GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_Hatching	Mouse	Brain	HP_ad_rep7	7.5e-07
H13	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
H13	GOBP_Intracellular_Protein_Transport	Mouse	Brain	HP_ad_rep7	3.6e-08
H13	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
H13	GOBP_Macromolecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-09
H13	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
H13	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
H13	GOBP_Protein_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
H13	GOBP_Protein_Exit_From_Endoplasmic_Reticulum	Mouse	Brain	HP_ad_rep7	6.8e-11
H13	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
H13	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	3.5e-10
H13	GOBP_Endoplasmic_Reticulum_To_Cytosol_Transport	Mouse	Brain	HP_ad_rep8	5.2e-09
H13	GOBP_Erad_Pathway	Mouse	Brain	HP_ad_rep8	5.7e-07
H13	GOBP_Cellular_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	7.2e-07
H13	GOBP_Proteasomal_Protein_Catabolic_Process	Mouse	Brain	HP_adpolb_rep1	1.1e-07
H13	GOBP_Signal_Peptide_Processing	Mouse	Brain	HP_adpolb_rep6	1.2e-07
H13	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
H13	GOBP_In_Utero_Embryonic_Development	Mouse	Brain	HP_polb_rep9	2.4e-10
H13	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
H13	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12
H13	GOBP_Response_To_Endoplasmic_Reticulum_Stress	Mouse	Brain	HP_polb_rep9	3.5e-12

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H13 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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H13 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for H13 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for H13

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for H13

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source