|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Fbln2 (spascer ID:14115) |
Gene summary for Fbln2 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Fbln2 | Gene ID | 14115 |
| Gene name | fibulin 2 |
| Synonyms | 5730577E14Rik|FIBL-2 |
| Cytomap | 6 D1|6 40.42 cM |
| Type of gene | protein-coding |
| Description | fibulin-2 |
| Modification date | 20220424 |
| UniProtAcc | P37889 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Fbln2 | GO:0010811 | positive regulation of cell-substrate adhesion | 21873635 | Process |
| Fbln2 | GO:0050840 | extracellular matrix binding | 21873635 | Function |
Top |
Spatial pattern events for Fbln2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Fbln2 | Mouse | Embryo | 1D | 34210887 | 2.39e-12 |
| Fbln2 | Mouse | Embryo | 1E | 34210887 | 6.89e-13 |
| Fbln2 | Mouse | Embryo | 1F | 34210887 | 5.37e-08 |
| Fbln2 | Mouse | Embryo | 1G | 34210887 | 1.93e-07 |
| Fbln2 | Mouse | Embryo | 3D | 34210887 | 1.60e-06 |
| Fbln2 | Mouse | Embryo | 3F | 34210887 | 9.62e-10 |
| Fbln2 | Mouse | Embryo | 3G | 34210887 | 4.33e-07 |
| Fbln2 | Mouse | Embryo | 4E | 34210887 | 1.44e-14 |
| Fbln2 | Mouse | Embryo | rep_1 | 33188776 | 1.82e-10 |
| Fbln2 | Mouse | Embryo | rep_2 | 33188776 | 1.37e-14 |
| Fbln2 | Mouse | Embryo | rep_3 | 33188776 | 1.13e-14 |
| Fbln2 | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Fbln2 | Mouse | Embryo | rep_5 | 33188776 | 3.86e-14 |
| Fbln2 | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Fbln2 | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Fbln2 | Mouse | Kidney | rep_5 | 34853151 | 1.49e-07 |
| Fbln2 | Mouse | Brain | rep_1 | 33469025 | 1.30e-15 |
| Fbln2 | Mouse | Intestine | rep_1 | 35149721 | 1.25e-08 |
| Fbln2 | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Fbln2 | Mouse | Testicle | rep_3 | 34731600 | 8.89e-03 |
| Fbln2 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Fbln2 | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Fbln2 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Fbln2 | Mouse | Lung | rep_2 | 35290801 | 7.23e-15 |
| Fbln2 | Mouse | Lung | rep_3 | 35290801 | 5.26e-15 |
| Fbln2 | Mouse | Lung | rep_4 | 35290801 | 3.04e-15 |
| Fbln2 | Mouse | Brain | OFB_ad_rep1 | 33083725 | 3.51e-03 |
| Fbln2 | Mouse | Brain | OFB_ad_rep2 | 33083725 | 7.29e-05 |
| Fbln2 | Mouse | Brain | OFB_ad_rep6 | 33083725 | 9.59e-03 |
| Fbln2 | Mouse | Brain | OFB_adpolb_rep3 | 33083725 | 4.76e-03 |
| Fbln2 | Mouse | Brain | OFB_adpolb_rep4 | 33083725 | 5.67e-06 |
| Fbln2 | Mouse | Brain | OFB_adpolb_rep5 | 33083725 | 2.31e-04 |
| Fbln2 | Mouse | Brain | OFB_polb_rep7 | 33083725 | 7.37e-09 |
| Fbln2 | Mouse | Brain | OFB_polb_rep8 | 33083725 | 2.44e-05 |
| Fbln2 | Mouse | Brain | OFB_wt_rep1 | 33083725 | 5.63e-04 |
| Fbln2 | Mouse | Brain | OFB_wt_rep2 | 33083725 | 1.43e-03 |
| Fbln2 | Mouse | Brain | OFB_wt_rep5 | 33083725 | 5.94e-07 |
| Fbln2 | Mouse | Brain | OFB_wt_rep6 | 33083725 | 2.15e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
Brain_OFB_ad_rep1_H&E  | |
Brain_OFB_ad_rep2_H&E  | |
Brain_OFB_ad_rep6_H&E  | |
Brain_OFB_adpolb_rep3_H&E  | |
Brain_OFB_adpolb_rep4_H&E  | |
Brain_OFB_adpolb_rep5_H&E  | |
Brain_OFB_polb_rep7_H&E  | |
Brain_OFB_polb_rep8_H&E  | |
Brain_OFB_wt_rep1_H&E  | |
Brain_OFB_wt_rep2_H&E  | |
Brain_OFB_wt_rep5_H&E  | |
Brain_OFB_wt_rep6_H&E  |
Top |
Spatial pattern pathway has Fbln2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Spinal cord | CN94_E1 | 1.2e-06 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Spinal cord | L7CN45_C1 | 2.4e-08 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Spinal cord | L7CN45_C1 | 4.9e-06 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Spinal cord | L7CN45_C1 | 9.3e-07 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Spinal cord | L7CN47_C1 | 4.8e-06 |
| Fbln2 | GOBP_Cell_Substrate_Adhesion | Mouse | Spinal cord | L7CN97_E2 | 2.2e-06 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Brain | rep_1 | 2.8e-21 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Brain | rep_1 | 1.4e-09 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Brain | rep_3 | 4.3e-106 |
| Fbln2 | GOBP_Cell_Substrate_Adhesion | Mouse | Brain | rep_3 | 1.8e-27 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Brain | rep_3 | 8.9e-180 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Brain | rep_3 | 3.0e-44 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Brain | rep_3 | 5.8e-98 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Embryo | rep_14 | 2.6e-09 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Embryo | rep_14 | 4.7e-08 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Embryo | rep_1 | 2.2e-19 |
| Fbln2 | GOBP_Cell_Substrate_Adhesion | Mouse | Embryo | rep_1 | 2.0e-34 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Embryo | rep_1 | 1.1e-140 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Embryo | rep_1 | 9.9e-230 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Embryo | rep_1 | 1.7e-08 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Embryo | rep_4 | 3.6e-11 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Embryo | rep_6 | 1.1e-18 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Kidney | rep_2 | 1.3e-48 |
| Fbln2 | GOBP_Cell_Substrate_Adhesion | Mouse | Kidney | rep_2 | 4.0e-46 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Kidney | rep_2 | 5.6e-85 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Kidney | rep_2 | 8.7e-44 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Kidney | rep_2 | 7.6e-38 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Kidney | rep_2 | 1.4e-76 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Kidney | rep_2 | 1.7e-26 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Liver | CN16-D2 | 2.6e-08 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Liver | CN73-C1 | 1.4e-08 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Liver | rep_16 | 2.1e-07 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Liver | rep_16 | 1.7e-12 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Lymph | MS-1 | 8.0e-14 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Lymph | MS-1 | 6.5e-12 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Adhesion | Mouse | Lymph | MS-1 | 3.0e-16 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Lymph | MS-1 | 3.3e-16 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Lymph | MS-1 | 4.4e-11 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Lung | rep_1 | 3.0e-22 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Lung | rep_1 | 1.3e-11 |
| Fbln2 | GOBP_Regulation_Of_Cell_Adhesion | Mouse | Lung | rep_1 | 2.2e-07 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Brain | rep_4 | 2.1e-07 |
| Fbln2 | GOBP_External_Encapsulating_Structure_Organization | Mouse | Brain | HP_ad_rep7 | 1.9e-11 |
| Fbln2 | GOBP_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Brain | HP_ad_rep7 | 1.8e-09 |
| Fbln2 | GOBP_Biological_Adhesion | Mouse | Brain | HP_polb_rep9 | 1.5e-07 |
| Fbln2 | GOBP_Cell_Substrate_Adhesion | Mouse | Brain | HP_polb_rep9 | 3.3e-07 |
| Fbln2 | GOBP_Positive_Regulation_Of_Cell_Substrate_Adhesion | Mouse | Brain | HP_polb_rep9 | 1.7e-07 |
Top |
Fbln2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Fbln2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Fbln2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Fbln2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Fbln2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
