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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Adgre1 (spascer ID:13733)

Gene summary for Adgre1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Adgre1
	Gene ID	13733
	Gene name	adhesion G protein-coupled receptor E1
	Synonyms	DD7A5-7\|EGF-TM7\|Emr1\|F4/80\|Gpf480\|Ly71\|TM7LN3
	Cytomap	17 D\|17 29.8 cM
	Type of gene	protein-coding
	Description	adhesion G protein-coupled receptor E1EGF-like module containing, mucin-like, hormone receptor-like sequence 1EGF-like module receptor 1EGF-like module-containing mucin-like hormone receptor-like 1EMR1 hormone receptorcell surface glycoprotein F4/80
	Modification date	20220503
	UniProtAcc	Q61549

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Adgre1	GO:0004930	G protein-coupled receptor activity	21873635	Function
Adgre1	GO:0005887	integral component of plasma membrane	21873635	Component
Adgre1	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	21873635	Process

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Spatial pattern events for Adgre1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Adgre1	Mouse	Brain	S1	34413515	2.70e-06
Adgre1	Mouse	Brain	S2	34413515	1.56e-15
Adgre1	Mouse	Brain	S6	34413515	2.00e-14
Adgre1	Mouse	Kidney	rep_1	34853151	2.42e-15
Adgre1	Mouse	Kidney	rep_5	34853151	1.02e-14
Adgre1	Mouse	Brain	rep_1	33469025	2.37e-15
Adgre1	Mouse	Liver	rep_20	35021063	9.91e-15
Adgre1	Mouse	Liver	rep_22	35021063	1.22e-10
Adgre1	Mouse	Lymph	A1	0	3.29e-15
Adgre1	Mouse	Lymph	B1	0	3.66e-15
Adgre1	Mouse	Lung	rep_3	35290801	7.15e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_1_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_20_H&E
Liver_rep_22_H&E
Lung_rep_3_H&E

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Spatial pattern pathway has Adgre1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	5.1e-07
Adgre1	GOBP_Biological_Adhesion	Mouse	Spinal cord	L7CN45_C1	2.4e-08
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Spinal cord	L8CN11_C1	4.7e-22
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	6.6e-06
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	8.0e-13
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	2.4e-17
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Brain	rep_3	1.9e-35
Adgre1	GOBP_Biological_Adhesion	Mouse	Brain	rep_3	4.3e-106
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Embryo	rep_14	9.8e-13
Adgre1	GOBP_Biological_Adhesion	Mouse	Embryo	rep_1	2.2e-19
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Embryo	rep_2	4.2e-56
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	8.0e-08
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_5	8.0e-08
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Kidney	rep_2	6.7e-132
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	1.3e-82
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	8.6e-64
Adgre1	GOBP_Biological_Adhesion	Mouse	Kidney	rep_2	1.3e-48
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Liver	CN16-D1	1.3e-07
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Liver	rep_16	1.5e-07
Adgre1	GOBP_Biological_Adhesion	Mouse	Liver	rep_16	2.1e-07
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Lymph	MS-1	1.6e-18
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	2.3e-11
Adgre1	GOBP_Biological_Adhesion	Mouse	Lymph	MS-1	8.0e-14
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Adgre1	GOBP_Biological_Adhesion	Mouse	Lung	rep_1	3.0e-22
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	3.9e-13
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_7	2.0e-12
Adgre1	GOBP_Adaptive_Immune_Response	Mouse	Brain	HP_ad_rep7	6.6e-10
Adgre1	GOBP_Adenylate_Cyclase_Activating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	8.8e-10
Adgre1	GOBP_Adenylate_Cyclase_Modulating_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	2.6e-10
Adgre1	GOBP_Biological_Adhesion	Mouse	Brain	HP_polb_rep9	1.5e-07
Adgre1	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16

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Adgre1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Adgre1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Adgre1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Adgre1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Adgre1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source