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Spatial pattern gene: Emp3 (spascer ID:13732) |
Gene summary for Emp3 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Emp3 | Gene ID | 13732 |
| Gene name | epithelial membrane protein 3 |
| Synonyms | H-4|H4|HNMP-1|MI-35|Ymp |
| Cytomap | 7 B3|7 29.6 cM |
| Type of gene | protein-coding |
| Description | epithelial membrane protein 3EMP-3hematopoietic neural membrane protein 1 |
| Modification date | 20220424 |
| UniProtAcc | O35912 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Emp3 | GO:0005886 | plasma membrane | 21873635 | Component |
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Spatial pattern events for Emp3 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Emp3 | Mouse | Brain | S1 | 34413515 | 3.03e-11 |
| Emp3 | Mouse | Brain | S2 | 34413515 | 1.61e-12 |
| Emp3 | Mouse | Brain | S6 | 34413515 | 1.46e-15 |
| Emp3 | Mouse | Brain | rep_2 | 35141374 | 1.69e-15 |
| Emp3 | Mouse | Brain | rep_3 | 35141374 | 1.64e-15 |
| Emp3 | Mouse | Brain | rep_4 | 35141374 | 1.57e-15 |
| Emp3 | Mouse | Brain | rep_5 | 35141374 | 1.47e-15 |
| Emp3 | Mouse | Brain | rep_6 | 35141374 | 1.73e-15 |
| Emp3 | Mouse | Embryo | rep_4 | 33188776 | 8.29e-15 |
| Emp3 | Mouse | Embryo | rep_12 | 33188776 | 4.84e-15 |
| Emp3 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Emp3 | Mouse | Kidney | Sham | 34003797 | 4.30e-15 |
| Emp3 | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Emp3 | Mouse | Kidney | rep_3 | 34853151 | 2.62e-09 |
| Emp3 | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Emp3 | Mouse | Brain | rep_1 | 33469025 | 1.01e-11 |
| Emp3 | Mouse | Intestine | rep_2 | 35149721 | 2.01e-07 |
| Emp3 | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Emp3 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Emp3 | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Emp3 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Emp3 | Mouse | Lung | rep_2 | 35290801 | 7.23e-15 |
| Emp3 | Mouse | Lung | rep_3 | 35290801 | 5.26e-15 |
| Emp3 | Mouse | Lung | rep_4 | 35290801 | 1.02e-14 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_2_H&E  |  |
Brain_rep_3_H&E  |  |
Brain_rep_4_H&E  |  |
Brain_rep_5_H&E  |  |
Brain_rep_6_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_5_H&E  |  |
Brain_rep_1_H&E  | |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
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Spatial pattern pathway has Emp3 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Emp3 | GOBP_Cell_Projection_Assembly | Mouse | Spinal cord | CN94_E1 | 3.2e-06 |
| Emp3 | GOBP_Bleb_Assembly | Mouse | Spinal cord | L7CN41_D1 | 2.2e-09 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Spinal cord | L7CN45_C1 | 1.2e-07 |
| Emp3 | GOBP_Cell_Projection_Assembly | Mouse | Brain | rep_1 | 8.3e-09 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Brain | rep_1 | 2.6e-08 |
| Emp3 | GOBP_Bleb_Assembly | Mouse | Embryo | rep_14 | 4.0e-41 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Embryo | rep_3 | 1.7e-72 |
| Emp3 | GOBP_Cell_Projection_Assembly | Mouse | Kidney | rep_2 | 3.6e-69 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Kidney | rep_2 | 4.1e-48 |
| Emp3 | GOBP_Bleb_Assembly | Mouse | Liver | rep_15 | 5.1e-20 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Liver | rep_16 | 3.4e-07 |
| Emp3 | GOBP_Bleb_Assembly | Mouse | Intestine | rep_2 | 8.5e-14 |
| Emp3 | GOBP_Cell_Projection_Assembly | Mouse | Lymph | MS-1 | 1.4e-09 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Lymph | MS-1 | 1.5e-09 |
| Emp3 | GOBP_Cell_Projection_Assembly | Mouse | Brain | HP_ad_rep7 | 1.0e-07 |
| Emp3 | GOBP_Cell_Projection_Organization | Mouse | Brain | HP_ad_rep7 | 8.1e-09 |
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Emp3 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Emp3 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Emp3 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Emp3 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Emp3 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Emp3 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Emp3 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
