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Spatial pattern gene: Emp1 (spascer ID:13730) |
Gene summary for Emp1 |
Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Emp1 | Gene ID | 13730 |
| Gene name | epithelial membrane protein 1 |
| Synonyms | I-8-09|TMP |
| Cytomap | 6 G1|6 66.25 cM |
| Type of gene | protein-coding |
| Description | epithelial membrane protein 1EMP-1tumor-associated membrane protein |
| Modification date | 20220424 |
| UniProtAcc | P47801 |
Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Emp1 | GO:0005886 | plasma membrane | 21873635 | Component |
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Spatial pattern events for Emp1 |
spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Emp1 | Mouse | Embryo | 1E | 34210887 | 3.99e-10 |
| Emp1 | Mouse | Embryo | 3D | 34210887 | 1.43e-10 |
| Emp1 | Mouse | Embryo | 3F | 34210887 | 2.87e-07 |
| Emp1 | Mouse | Embryo | 3G | 34210887 | 9.03e-12 |
| Emp1 | Mouse | Embryo | 4D | 34210887 | 9.56e-07 |
| Emp1 | Mouse | Embryo | 4E | 34210887 | 1.44e-14 |
| Emp1 | Mouse | Embryo | rep_3 | 33188776 | 1.97e-07 |
| Emp1 | Mouse | Embryo | rep_4 | 33188776 | 5.95e-10 |
| Emp1 | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Emp1 | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Emp1 | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Emp1 | Mouse | Kidney | rep_1 | 34853151 | 7.83e-15 |
| Emp1 | Mouse | Kidney | rep_2 | 34853151 | 3.38e-15 |
| Emp1 | Mouse | Kidney | rep_4 | 34853151 | 4.07e-15 |
| Emp1 | Mouse | Kidney | rep_5 | 34853151 | 1.44e-11 |
| Emp1 | Mouse | Liver | rep_20 | 35021063 | 3.12e-10 |
| Emp1 | Mouse | Liver | rep_21 | 35021063 | 8.03e-15 |
| Emp1 | Mouse | Liver | rep_22 | 35021063 | 6.32e-10 |
| Emp1 | Mouse | Intestine | rep_1 | 35149721 | 6.08e-15 |
| Emp1 | Mouse | Intestine | rep_2 | 35149721 | 3.44e-15 |
| Emp1 | Mouse | Intestine | rep_3 | 35149721 | 3.25e-15 |
| Emp1 | Mouse | Intestine | rep_4 | 35149721 | 2.30e-15 |
| Emp1 | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Emp1 | Mouse | Lymph | B1 | 0 | 3.66e-15 |
| Emp1 | Mouse | Lung | rep_1 | 35290801 | 4.52e-15 |
| Emp1 | Mouse | Lung | rep_2 | 35290801 | 7.23e-15 |
| Emp1 | Mouse | Lung | rep_3 | 35290801 | 5.26e-15 |
| Emp1 | Mouse | Lung | rep_4 | 35290801 | 3.04e-15 |
spatial pattern gene map.(click to enlarge the image in a new window) |
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Spatial pattern pathway has Emp1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Emp1 | GOBP_Cell_Projection_Assembly | Mouse | Spinal cord | CN94_E1 | 3.2e-06 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Spinal cord | CN94_E1 | 8.2e-07 |
| Emp1 | GOBP_Bleb_Assembly | Mouse | Spinal cord | L7CN41_D1 | 2.2e-09 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Spinal cord | L7CN45_C1 | 1.2e-07 |
| Emp1 | GOBP_Cell_Projection_Assembly | Mouse | Brain | rep_1 | 8.3e-09 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Brain | rep_1 | 2.6e-08 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Brain | rep_3 | 3.2e-173 |
| Emp1 | GOBP_Bleb_Assembly | Mouse | Embryo | rep_14 | 4.0e-41 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Embryo | rep_3 | 1.7e-72 |
| Emp1 | GOBP_Cell_Projection_Assembly | Mouse | Kidney | rep_2 | 3.6e-69 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Kidney | rep_2 | 4.1e-48 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Kidney | rep_2 | 3.0e-27 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Liver | CN16-D2 | 1.2e-09 |
| Emp1 | GOBP_Bleb_Assembly | Mouse | Liver | rep_15 | 5.1e-20 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Liver | rep_16 | 3.4e-07 |
| Emp1 | GOBP_Bleb_Assembly | Mouse | Intestine | rep_2 | 8.5e-14 |
| Emp1 | GOBP_Cell_Projection_Assembly | Mouse | Lymph | MS-1 | 1.4e-09 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Lymph | MS-1 | 1.5e-09 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Lymph | MS-1 | 4.0e-14 |
| Emp1 | GOBP_Cell_Projection_Assembly | Mouse | Brain | HP_ad_rep7 | 1.0e-07 |
| Emp1 | GOBP_Cell_Projection_Organization | Mouse | Brain | HP_ad_rep7 | 8.1e-09 |
| Emp1 | GOBP_Epidermis_Development | Mouse | Brain | HP_polb_rep9 | 5.3e-12 |
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Emp1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Emp1 function as liang/receptor across spatial transcriptomics tissue |
Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Emp1 envolved |
Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
Motif information. |
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Related Drugs for Emp1 |
Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Emp1 |
Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Emp1 | C0000786 | Spontaneous abortion | 1 | CTD_human |
| Emp1 | C0000822 | Abortion, Tubal | 1 | CTD_human |
| Emp1 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Emp1 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Emp1 | C0041696 | Unipolar Depression | 1 | PSYGENET |
| Emp1 | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
| Emp1 | C1269683 | Major Depressive Disorder | 1 | PSYGENET |
| Emp1 | C3830362 | Early Pregnancy Loss | 1 | CTD_human |
| Emp1 | C4552766 | Miscarriage | 1 | CTD_human |