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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Elf5 (spascer ID:13711)

Gene summary for Elf5

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Elf5

Gene ID

13711

Gene nameE74-like factor 5
SynonymsESE-2|ESE-5|ESE-5.
Cytomap2|2 E2
Type of geneprotein-coding
DescriptionETS-related transcription factor Elf-5Epithelium specific Ets-2
Modification date20220424
UniProtAcc

Q8VDK3


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Elf5

GO:0000981

DNA-binding transcription factor activity, RNA polymerase II-specific

21873635

Function
Elf5

GO:0005634

nucleus

21873635

Component
Elf5

GO:0006357

regulation of transcription by RNA polymerase II

21873635

Process
Elf5

GO:0030154

cell differentiation

21873635

Process

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Spatial pattern events for Elf5

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Elf5MouseEmbryorep_1 344896003.74e-16
Elf5MouseEmbryorep_2 344896004.14e-16
Elf5MouseEmbryorep_4 344896003.67e-16
Elf5MouseEmbryorep_5 344896004.08e-16
Elf5MouseKidneyCLP 340037972.19e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_CLP_H&E
boxplot

boxplot


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Spatial pattern pathway has Elf5 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value

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Elf5 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Elf5 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Elf5 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score
Elf5KidneyLPSPT_S3_OSOlfm1,Aqp4,Grem2, etc.0.31
Elf5KidneyLPSTALOlfm1,Aqp4,Grem2, etc.0.338
Elf5KidneyLPSCNTOlfm1,Aqp4,Grem2, etc.0.262
Elf5KidneyLPSPT_S2Olfm1,Aqp4,Grem2, etc.0.268
Elf5KidneyLPSPT_S3_COlfm1,Aqp4,Grem2, etc.0.321

check button Motif information.
boxplot

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Related Drugs for Elf5

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Elf5

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource