SPASCER Logo

Home

Download & Upload

Statistics

Landscape

Help

Contact
Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Eif3a (spascer ID:13669)

Gene summary for Eif3a

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Eif3a

Gene ID

13669

Gene nameeukaryotic translation initiation factor 3, subunit A
SynonymsA830012B05Rik|Csma|Eif3|Eif3s10|mKIAA0139
Cytomap19|19 D3
Type of geneprotein-coding
Descriptioneukaryotic translation initiation factor 3 subunit AEUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN)centrosomineIF-3-thetaeIF3 p167eIF3 p180eIF3 p185eukaryotic tran
Modification date20220424
UniProtAcc

P23116


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Eif3a

GO:0001732

formation of cytoplasmic translation initiation complex

21873635

Process
Eif3a

GO:0002188

translation reinitiation

21873635

Process
Eif3a

GO:0003729

mRNA binding

21873635

Function
Eif3a

GO:0003743

translation initiation factor activity

21873635

Function
Eif3a

GO:0043614

multi-eIF complex

21873635

Component
Eif3a

GO:0071540

eukaryotic translation initiation factor 3 complex, eIF3e

21873635

Component
Eif3a

GO:0071541

eukaryotic translation initiation factor 3 complex, eIF3m

21873635

Component

Top

Spatial pattern events for Eif3a

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Eif3aMouseBrainrep_4 351413748.71e-06
Eif3aMouseEmbryo4E 342108871.33e-08
Eif3aMouseEmbryorep_1 331887761.49e-06
Eif3aMouseEmbryorep_3 331887763.28e-14
Eif3aMouseKidneyIRI 340037976.75e-06
Eif3aMouseKidneyrep_1 348531512.23e-07
Eif3aMouseKidneyrep_2 348531513.15e-11
Eif3aMouseKidneyrep_3 348531515.07e-06
Eif3aMouseBrainrep_2 350277291.37e-06
Eif3aMouseBrainrep_3 350277292.18e-08
Eif3aMouseIntestinerep_4 351497214.09e-08
Eif3aMouseTesticlerep_4 347316001.14e-15
Eif3aMouseLymphB1 06.08e-15
Eif3aMouseLungrep_4 352908012.67e-09
Eif3aMouseBrainrep_5 352106241.29e-10
Eif3aMouseBrainrep_6 352106243.65e-15
Eif3aMouseBrainrep_7 352106241.87e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_4_H&E
boxplot
boxplot
Kidney_IRI_H&E
boxplot
boxplot
Kidney_rep_1_H&E
boxplot
boxplot
Kidney_rep_2_H&E
boxplot
boxplot
Kidney_rep_3_H&E
boxplot
boxplot
Brain_rep_2_H&E
boxplot
boxplot
Brain_rep_3_H&E
boxplot
boxplot
Lung_rep_4_H&E
boxplot
boxplot


Top

Spatial pattern pathway has Eif3a envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseSpinal cordCN94_E1 4.0e-06
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseSpinal cordCN94_E1 7.0e-06
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseSpinal cordL7bCN02_E1 8.5e-06
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseSpinal cordL7CN45_C1 2.2e-09
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseSpinal cordL7CN45_C1 3.4e-09
Eif3aGOBP_Cytoplasmic_TranslationMouseSpinal cordL7CN45_C1 1.4e-06
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseSpinal cordL7CN45_C1 7.6e-09
Eif3aGOBP_Mapk_CascadeMouseSpinal cordL7CN45_C1 1.7e-07
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseSpinal cordL7CN45_C1 5.6e-08
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseSpinal cordL7CN45_C1 3.5e-08
Eif3aGOBP_Peptide_Metabolic_ProcessMouseSpinal cordL7CN45_C1 3.4e-09
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseSpinal cordL7CN45_C1 1.4e-06
Eif3aGOBP_Ribonucleoprotein_Complex_Subunit_OrganizationMouseSpinal cordL7CN45_C1 1.2e-07
Eif3aGOBP_Translational_InitiationMouseSpinal cordL7CN45_C1 1.6e-08
Eif3aGOBP_Viral_Gene_ExpressionMouseSpinal cordL7CN45_C1 5.3e-10
Eif3aGOBP_Viral_TranslationMouseSpinal cordL7CN45_C1 5.1e-08
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseSpinal cordL7CN47_D1 3.2e-06
Eif3aGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseSpinal cordL7CN97_E2 6.8e-06
Eif3aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseSpinal cordL8CN11_D1 5.6e-09
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseSpinal cordL8CN17_E1 8.3e-06
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseBrainrep_34 2.5e-05
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseBrainrep_71 2.3e-05
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseBrainrep_75 4.9e-05
Eif3aGOBP_Viral_TranslationMouseBrainrep_75 4.7e-05
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseBrainrep_3 2.5e-86
Eif3aGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainrep_31.9e-146
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseBrainrep_3 2.1e-87
Eif3aGOBP_Cytoplasmic_TranslationMouseBrainrep_3 2.1e-11
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseBrainrep_31.1e-199
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseBrainrep_3 2.0e-29
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseBrainrep_37.9e-217
Eif3aGOBP_Mapk_CascadeMouseBrainrep_34.8e-123
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseBrainrep_3 2.5e-67
Eif3aGOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionMouseBrainrep_39.2e-120
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseBrainrep_33.0e-156
Eif3aGOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainrep_31.3e-138
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseBrainrep_37.8e-106
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseBrainrep_32.9e-144
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseBrainrep_3 2.1e-69
Eif3aGOBP_Peptide_Metabolic_ProcessMouseBrainrep_3 1.3e-86
Eif3aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainrep_31.3e-132
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseBrainrep_3 5.6e-32
Eif3aGOBP_Ribonucleoprotein_Complex_Subunit_OrganizationMouseBrainrep_3 6.1e-80
Eif3aGOBP_Translational_InitiationMouseBrainrep_31.2e-197
Eif3aGOBP_Viral_Gene_ExpressionMouseBrainrep_34.6e-154
Eif3aGOBP_Viral_TranslationMouseBrainrep_35.6e-213
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseBrainrep_35.7e-128
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseEmbryorep_14 3.7e-18
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseEmbryorep_14 4.7e-16
Eif3aGOBP_Cytoplasmic_TranslationMouseEmbryorep_14 4.6e-30
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseEmbryorep_14 2.5e-22
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseEmbryorep_14 4.9e-11
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseEmbryorep_14 1.0e-08
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseEmbryorep_14 9.4e-48
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseEmbryorep_14 2.4e-12
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseEmbryorep_14 2.8e-15
Eif3aGOBP_Peptide_Metabolic_ProcessMouseEmbryorep_14 4.7e-16
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseEmbryorep_14 2.1e-33
Eif3aGOBP_Ribonucleoprotein_Complex_Subunit_OrganizationMouseEmbryorep_14 6.2e-25
Eif3aGOBP_Translational_InitiationMouseEmbryorep_14 1.2e-37
Eif3aGOBP_Viral_TranslationMouseEmbryorep_14 3.0e-16
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseEmbryorep_14 1.0e-38
Eif3aGOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionMouseEmbryorep_1 1.0e-64
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseEmbryorep_1 1.3e-40
Eif3aGOBP_Negative_Regulation_Of_Response_To_StimulusMouseEmbryorep_1 1.1e-25
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseEmbryorep_1 5.6e-10
Eif3aGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseEmbryorep_27.4e-121
Eif3aGOBP_Viral_Gene_ExpressionMouseEmbryorep_2 3.8e-28
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseEmbryorep_6 5.6e-45
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseKidneyrep_2 1.9e-84
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseKidneyrep_2 2.5e-85
Eif3aGOBP_Cytoplasmic_TranslationMouseKidneyrep_2 2.1e-75
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseKidneyrep_2 2.9e-68
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseKidneyrep_2 1.2e-29
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseKidneyrep_29.1e-121
Eif3aGOBP_Mapk_CascadeMouseKidneyrep_2 1.1e-19
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseKidneyrep_2 2.2e-12
Eif3aGOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionMouseKidneyrep_2 9.1e-83
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseKidneyrep_2 7.9e-08
Eif3aGOBP_Negative_Regulation_Of_Response_To_StimulusMouseKidneyrep_2 1.7e-39
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseKidneyrep_2 4.0e-40
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseKidneyrep_2 8.9e-78
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseKidneyrep_2 2.9e-85
Eif3aGOBP_Peptide_Metabolic_ProcessMouseKidneyrep_2 1.4e-80
Eif3aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseKidneyrep_2 1.4e-17
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseKidneyrep_2 1.3e-69
Eif3aGOBP_Ribonucleoprotein_Complex_Subunit_OrganizationMouseKidneyrep_2 3.3e-25
Eif3aGOBP_Translational_InitiationMouseKidneyrep_21.3e-103
Eif3aGOBP_Viral_Gene_ExpressionMouseKidneyrep_2 7.6e-94
Eif3aGOBP_Viral_TranslationMouseKidneyrep_25.5e-136
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseKidneyrep_2 1.7e-63
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseLiverCN16-D2 2.3e-16
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseLiverCN16-D2 4.3e-08
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseLiverCN16-D2 1.2e-09
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseLiverCN73-C1 4.0e-09
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseLiverrep_15 1.9e-08
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseLiverrep_16 1.3e-09
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseLymphMS-1 1.3e-09
Eif3aGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseLymphMS-1 4.6e-18
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseLymphMS-1 5.8e-11
Eif3aGOBP_Cytoplasmic_TranslationMouseLymphMS-1 7.1e-07
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseLymphMS-1 9.3e-07
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseLymphMS-1 1.2e-19
Eif3aGOBP_Mapk_CascadeMouseLymphMS-1 8.8e-20
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseLymphMS-1 1.5e-09
Eif3aGOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionMouseLymphMS-1 1.5e-16
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseLymphMS-1 7.4e-13
Eif3aGOBP_Negative_Regulation_Of_Response_To_StimulusMouseLymphMS-1 1.5e-11
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseLymphMS-1 1.0e-14
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseLymphMS-1 1.4e-09
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseLymphMS-1 7.1e-07
Eif3aGOBP_Peptide_Metabolic_ProcessMouseLymphMS-1 5.8e-11
Eif3aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseLymphMS-1 1.0e-14
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseLymphMS-1 1.7e-07
Eif3aGOBP_Translational_InitiationMouseLymphMS-1 7.5e-07
Eif3aGOBP_Viral_Gene_ExpressionMouseLymphMS-1 1.4e-09
Eif3aGOBP_Viral_TranslationMouseLymphMS-2 2.2e-08
Eif3aGOBP_Viral_Translational_Termination_ReinitiationMouseBrainHP_ad_rep2 2.7e-07
Eif3aGOBP_Amide_Biosynthetic_ProcessMouseBrainHP_ad_rep7 8.0e-10
Eif3aGOBP_Cellular_Amide_Metabolic_ProcessMouseBrainHP_ad_rep7 5.6e-11
Eif3aGOBP_Negative_Regulation_Of_Erk1_And_Erk2_CascadeMouseBrainHP_ad_rep7 3.1e-07
Eif3aGOBP_Organonitrogen_Compound_Biosynthetic_ProcessMouseBrainHP_ad_rep7 2.8e-08
Eif3aGOBP_Peptide_Biosynthetic_ProcessMouseBrainHP_ad_rep7 4.4e-10
Eif3aGOBP_Peptide_Metabolic_ProcessMouseBrainHP_ad_rep7 2.8e-10
Eif3aGOBP_Ribonucleoprotein_Complex_BiogenesisMouseBrainHP_ad_rep7 7.9e-07
Eif3aGOBP_Ribonucleoprotein_Complex_Subunit_OrganizationMouseBrainHP_ad_rep7 8.3e-08
Eif3aGOBP_Translational_InitiationMouseBrainHP_ad_rep7 6.9e-08
Eif3aGOBP_Cytoplasmic_TranslationMouseBrainHP_ad_rep8 1.4e-08
Eif3aGOBP_Cytoplasmic_Translational_InitiationMouseBrainHP_adpolb_rep1 4.3e-07
Eif3aGOBP_Ires_Dependent_Viral_Translational_InitiationMouseBrainHP_adpolb_rep1 6.9e-13
Eif3aGOBP_Viral_TranslationMouseBrainHP_adpolb_rep1 3.4e-15
Eif3aGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainHP_polb_rep9 1.1e-12
Eif3aGOBP_Erk1_And_Erk2_CascadeMouseBrainHP_polb_rep9 2.8e-07
Eif3aGOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionMouseBrainHP_polb_rep9 9.4e-11
Eif3aGOBP_Negative_Regulation_Of_Mapk_CascadeMouseBrainHP_polb_rep9 8.9e-08
Eif3aGOBP_Negative_Regulation_Of_Response_To_StimulusMouseBrainHP_polb_rep9 3.1e-09
Eif3aGOBP_Negative_Regulation_Of_SignalingMouseBrainHP_polb_rep9 1.4e-11
Eif3aGOBP_Regulation_Of_Intracellular_Signal_TransductionMouseBrainHP_polb_rep9 3.9e-11
Eif3aGOBP_Viral_Gene_ExpressionMouseBrainHP_polb_rep9 1.1e-14

Top

Eif3a function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

Top

Eif3a function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

Top

Transcription factor for Eif3a envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

Top

Related Drugs for Eif3a

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for Eif3a

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
Eif3aC0033578Prostatic Neoplasms1CTD_human
Eif3aC0376358Malignant neoplasm of prostate1CTD_human