|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Ehf (spascer ID:13661) |
Gene summary for Ehf |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Ehf | Gene ID | 13661 |
| Gene name | ets homologous factor |
| Synonyms | 9030625L19Rik|AU019492 |
| Cytomap | 2|2 E2 |
| Type of gene | protein-coding |
| Description | ETS homologous factorETS domain-containing transcription factor |
| Modification date | 20220424 |
| UniProtAcc | O70273 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Ehf | GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | 21873635 | Function |
| Ehf | GO:0005634 | nucleus | 21873635 | Component |
| Ehf | GO:0006357 | regulation of transcription by RNA polymerase II | 21873635 | Process |
| Ehf | GO:0030154 | cell differentiation | 21873635 | Process |
Top |
Spatial pattern events for Ehf |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Ehf | Mouse | Kidney | CLP | 34003797 | 2.19e-15 |
| Ehf | Mouse | Kidney | IRI | 34003797 | 2.29e-15 |
| Ehf | Mouse | Kidney | Sham | 34003797 | 2.58e-15 |
| Ehf | Mouse | Kidney | rep_1 | 34853151 | 2.42e-15 |
| Ehf | Mouse | Kidney | rep_3 | 34853151 | 2.94e-15 |
| Ehf | Mouse | Kidney | rep_4 | 34853151 | 4.07e-15 |
| Ehf | Mouse | Kidney | rep_5 | 34853151 | 3.18e-15 |
| Ehf | Mouse | Intestine | rep_1 | 35149721 | 1.18e-06 |
| Ehf | Mouse | Intestine | rep_2 | 35149721 | 1.00e-14 |
| Ehf | Mouse | Intestine | rep_3 | 35149721 | 9.60e-15 |
| Ehf | Mouse | Lung | rep_1 | 35290801 | 7.46e-10 |
| Ehf | Mouse | Lung | rep_2 | 35290801 | 1.81e-13 |
| Ehf | Mouse | Lung | rep_3 | 35290801 | 9.91e-13 |
| Ehf | Mouse | Lung | rep_4 | 35290801 | 1.75e-11 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_CLP_H&E  |  |
Kidney_IRI_H&E  |  |
Kidney_Sham_H&E  |  |
Kidney_rep_1_H&E  |  |
Kidney_rep_3_H&E  |  |
Kidney_rep_4_H&E  |  |
Kidney_rep_5_H&E  |  |
Lung_rep_1_H&E  |  |
Lung_rep_2_H&E  |  |
Lung_rep_3_H&E  |  |
Lung_rep_4_H&E  |  |
Top |
Spatial pattern pathway has Ehf envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Ehf | GOBP_Epithelial_Cell_Differentiation | Mouse | Spinal cord | CN94_E1 | 2.3e-07 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Spinal cord | L7CN45_C1 | 4.2e-06 |
| Ehf | GOBP_Epithelium_Development | Mouse | Spinal cord | L7CN45_C1 | 4.2e-06 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Spinal cord | L7CN45_C1 | 1.4e-06 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Brain | rep_72 | 3.4e-06 |
| Ehf | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | rep_1 | 2.5e-12 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | rep_1 | 1.6e-17 |
| Ehf | GOBP_Epithelial_Cell_Differentiation | Mouse | Brain | rep_3 | 4.7e-108 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Brain | rep_3 | 1.4e-179 |
| Ehf | GOBP_Epithelium_Development | Mouse | Brain | rep_3 | 8.3e-102 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Embryo | rep_1 | 0.0e+00 |
| Ehf | GOBP_Epithelium_Development | Mouse | Embryo | rep_1 | 1.7e-09 |
| Ehf | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Embryo | rep_3 | 0.0e+00 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Embryo | rep_3 | 0.0e+00 |
| Ehf | GOBP_Epithelial_Cell_Differentiation | Mouse | Kidney | rep_2 | 4.2e-114 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Kidney | rep_2 | 1.8e-43 |
| Ehf | GOBP_Epithelium_Development | Mouse | Kidney | rep_2 | 3.5e-92 |
| Ehf | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Kidney | rep_2 | 4.5e-10 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Kidney | rep_2 | 8.3e-40 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Liver | CN73-C1 | 1.7e-07 |
| Ehf | GOBP_Epithelial_Cell_Differentiation | Mouse | Lymph | MS-1 | 1.2e-07 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Lymph | MS-1 | 1.0e-07 |
| Ehf | GOBP_Epithelium_Development | Mouse | Lymph | MS-1 | 8.5e-09 |
| Ehf | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Lymph | MS-1 | 4.4e-12 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Lymph | MS-1 | 1.7e-12 |
| Ehf | GOBP_Epithelial_Cell_Differentiation | Mouse | Brain | HP_ad_rep7 | 1.7e-13 |
| Ehf | GOBP_Epithelial_Cell_Proliferation | Mouse | Brain | HP_ad_rep7 | 8.1e-09 |
| Ehf | GOBP_Epithelium_Development | Mouse | Brain | HP_ad_rep7 | 2.8e-08 |
| Ehf | GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-11 |
| Ehf | GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii | Mouse | Brain | HP_ad_rep7 | 7.3e-11 |
Top |
Ehf function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Ehf function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication | ||
Top |
Transcription factor for Ehf envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Ehf | Kidney | LPS | TAL | Plekhg3,Purb,Med29, etc. | 0.359 |
| Ehf | Kidney | LPS | PT_S3_C | Plekhg3,Purb,Med29, etc. | 0.263 |
| Ehf | Kidney | LPS | CD_IC | Plekhg3,Purb,Med29, etc. | 0.254 |
| Ehf | Kidney | LPS | CD_PC | Plekhg3,Purb,Med29, etc. | 0.267 |
| EHF | Skin | control | Normal_KC_Basal | S100A8,S100A9,NDRG1, etc. | 0.34 |
| EHF | Skin | control | Normal_KC_Diff | S100A8,S100A9,NDRG1, etc. | 0.518 |
| EHF | Skin | control | Normal_KC_Cyc | S100A8,S100A9,NDRG1, etc. | 0.266 |
| EHF | Skin | tumor | Tumor_KC_Diff | NEAT1,GATA3,MINK1, etc. | 0.291 |
| EHF | Skin | tumor | Keratinocyte | NEAT1,GATA3,MINK1, etc. | 0.414 |
| EHF | Skin | tumor | CD1C | NEAT1,GATA3,MINK1, etc. | 0.28 |
| EHF | Skin | tumor | Mac | NEAT1,GATA3,MINK1, etc. | 0.261 |
| Ehf | Kidney | IRI | PT_S1 | Aqp2,Aqp3,Olfm1, etc. | 0.306 |
| Ehf | Kidney | IRI | CNT | Aqp2,Aqp3,Olfm1, etc. | 0.258 |
| Ehf | Kidney | IRI | PT_S3_C | Aqp2,Aqp3,Olfm1, etc. | 0.289 |
| Ehf | Kidney | IRI | PT_Fibrinogen | Aqp2,Aqp3,Olfm1, etc. | 0.267 |
| Ehf | Kidney | IRI | CD_IC | Aqp2,Aqp3,Olfm1, etc. | 0.271 |
| Ehf | Kidney | IRI | TAL | Aqp2,Aqp3,Olfm1, etc. | 0.285 |
| Ehf | Kidney | IRI | CD_PC | Aqp2,Aqp3,Olfm1, etc. | 0.268 |
| Ehf | Kidney | Sham | CNT | St14,Blnk,Cldn7, etc. | 0.253 |
| Ehf | Kidney | Sham | PT_S3_OS | St14,Blnk,Cldn7, etc. | 0.267 |
| Ehf | Kidney | Sham | PT_S3_C | St14,Blnk,Cldn7, etc. | 0.358 |
| Ehf | Kidney | Sham | PT_Fibrinogen | St14,Blnk,Cldn7, etc. | 0.277 |
| Ehf | Kidney | Sham | VSM | St14,Blnk,Cldn7, etc. | 0.25 |
| Ehf | Kidney | Sham | PT_S1 | St14,Blnk,Cldn7, etc. | 0.267 |
| Ehf | Kidney | Sham | TAL | St14,Blnk,Cldn7, etc. | 0.319 |
| Motif information. |
 | |
 | |
 | |
Top |
Related Drugs for Ehf |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Ehf |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Ehf | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Ehf | C0376358 | Malignant neoplasm of prostate | 1 | CTD_human |
