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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Klk1b22 (spascer ID:13646)

Gene summary for Klk1b22

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Klk1b22
	Gene ID	13646
	Gene name	kallikrein 1-related peptidase b22
	Synonyms	EGF-BP A\|Egfbp-1\|Egfbp1\|Klk22\|mGk-22
	Cytomap	7 B3\|7 28.61 cM
	Type of gene	protein-coding
	Description	kallikrein 1-related peptidase b22beta-NGF-endopeptidaseepidermal growth factor-binding protein type Aglandular kallikrein K22nerve growth factor beta chain endopeptidasetissue kallikrein 22
	Modification date	20220424
	UniProtAcc	P15948

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Klk1b22	GO:0003073	regulation of systemic arterial blood pressure	21873635	Process
Klk1b22	GO:0030141	secretory granule	21873635	Component
Klk1b22	GO:0031638	zymogen activation	21873635	Process

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Spatial pattern events for Klk1b22

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Klk1b22	Mouse	Kidney	CLP	34003797	8.25e-08
Klk1b22	Mouse	Kidney	IRI	34003797	3.92e-15
Klk1b22	Mouse	Kidney	Sham	34003797	3.66e-10
Klk1b22	Mouse	Testicle	rep_6	34731600	3.17e-11

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E

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Spatial pattern pathway has Klk1b22 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Spinal cord	CN93_D2	2.2e-06
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Spinal cord	CN94_E1	1.2e-06
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Spinal cord	CN94_E1	4.0e-08
Klk1b22	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Spinal cord	L7CN44_C1	1.1e-06
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Spinal cord	L7CN45_C1	7.0e-06
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.0e-07
Klk1b22	GOBP_Cellular_Component_Disassembly	Mouse	Spinal cord	L7CN45_C1	1.0e-06
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Spinal cord	L7CN45_C1	5.7e-08
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Spinal cord	L7CN45_C1	2.6e-06
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Spinal cord	L7CN45_C1	1.3e-07
Klk1b22	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Spinal cord	L7CN45_C1	1.9e-10
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Spinal cord	L7CN45_C1	8.9e-09
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Spinal cord	L7CN45_C1	2.2e-07
Klk1b22	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Klk1b22	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Spinal cord	L7CN45_C1	4.0e-08
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Klk1b22	GOBP_Tube_Development	Mouse	Spinal cord	L7CN45_C1	4.2e-06
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Klk1b22	GOBP_Vasculature_Development	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Spinal cord	L7CN47_C1	8.3e-06
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Spinal cord	L7CN47_D1	1.9e-09
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Spinal cord	L7CN97_E2	7.9e-07
Klk1b22	GOBP_Defense_Response	Mouse	Spinal cord	L8CN11_C1	3.3e-17
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Spinal cord	L8CN17_E1	2.2e-06
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Spinal cord	L8CN17_E1	2.6e-06
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Brain	rep_41	5.9e-09
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Brain	rep_41	1.6e-05
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Brain	rep_75	2.7e-05
Klk1b22	GOBP_Cellular_Component_Disassembly	Mouse	Brain	rep_1	1.5e-15
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	rep_3	5.3e-58
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Brain	rep_3	3.1e-188
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Brain	rep_3	7.1e-173
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	rep_3	7.4e-87
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Brain	rep_3	1.3e-81
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Brain	rep_3	2.0e-61
Klk1b22	GOBP_Defense_Response	Mouse	Brain	rep_3	8.7e-77
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Brain	rep_3	4.4e-161
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	rep_3	6.0e-105
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	rep_3	8.9e-180
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Brain	rep_3	2.6e-91
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Brain	rep_3	2.5e-108
Klk1b22	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	rep_3	3.9e-71
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	rep_3	2.0e-111
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Brain	rep_3	2.8e-170
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Brain	rep_3	2.6e-183
Klk1b22	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Klk1b22	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
Klk1b22	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	rep_3	3.2e-44
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	rep_3	5.2e-95
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Brain	rep_3	2.1e-61
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Brain	rep_3	3.1e-78
Klk1b22	GOBP_Tube_Development	Mouse	Brain	rep_3	9.0e-136
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Brain	rep_3	4.7e-120
Klk1b22	GOBP_Vasculature_Development	Mouse	Brain	rep_3	2.6e-82
Klk1b22	GOBP_Zymogen_Activation	Mouse	Brain	rep_3	9.8e-13
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Embryo	rep_6	1.6e-12
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Embryo	rep_6	1.0e-10
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_6	2.4e-08
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Embryo	rep_6	4.5e-11
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Embryo	rep_14	1.5e-52
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Embryo	rep_14	1.3e-76
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Embryo	rep_14	1.5e-78
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Embryo	rep_14	1.4e-25
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Embryo	rep_14	6.4e-58
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Embryo	rep_14	3.9e-34
Klk1b22	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Klk1b22	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Embryo	rep_14	1.6e-07
Klk1b22	GOBP_Zymogen_Activation	Mouse	Embryo	rep_14	1.1e-65
Klk1b22	GOBP_Defense_Response	Mouse	Embryo	rep_1	5.2e-63
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Embryo	rep_1	1.5e-209
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Embryo	rep_1	2.8e-203
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Embryo	rep_1	2.0e-28
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Embryo	rep_2	7.8e-113
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Embryo	rep_3	2.6e-164
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Embryo	rep_5	1.8e-10
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Embryo	rep_6	3.8e-28
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Embryo	rep_6	1.6e-86
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Embryo	rep_6	1.1e-18
Klk1b22	GOBP_Vasculature_Development	Mouse	Embryo	rep_6	1.9e-41
Klk1b22	GOBP_Antibacterial_Peptide_Production	Mouse	Kidney	IRI	7.2e-91
Klk1b22	GOBP_Antimicrobial_Peptide_Production	Mouse	Kidney	IRI	7.2e-91
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Kidney	IRI	1.5e-08
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Kidney	IRI	8.3e-53
Klk1b22	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Klk1b22	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	IRI	9.0e-58
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	IRI	2.4e-84
Klk1b22	GOBP_Zymogen_Activation	Mouse	Kidney	IRI	4.7e-64
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	Nep	1.3e-32
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	Nep	1.3e-32
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Kidney	Nep	2.6e-47
Klk1b22	GOBP_Tube_Development	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Vasculature_Development	Mouse	Kidney	Nep	5.6e-37
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Kidney	rep_1	7.9e-10
Klk1b22	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Kidney	rep_1	2.1e-07
Klk1b22	GOBP_Zymogen_Activation	Mouse	Kidney	rep_1	5.3e-07
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Kidney	rep_2	5.6e-148
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Kidney	rep_2	4.2e-104
Klk1b22	GOBP_Antibacterial_Peptide_Production	Mouse	Kidney	rep_2	1.4e-96
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Kidney	rep_2	1.1e-102
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Kidney	rep_2	4.7e-106
Klk1b22	GOBP_Antimicrobial_Peptide_Production	Mouse	Kidney	rep_2	1.4e-96
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Kidney	rep_2	3.2e-114
Klk1b22	GOBP_Cellular_Component_Disassembly	Mouse	Kidney	rep_2	4.2e-70
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Kidney	rep_2	6.7e-139
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Kidney	rep_2	1.4e-100
Klk1b22	GOBP_Defense_Response	Mouse	Kidney	rep_2	6.8e-127
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Kidney	rep_2	3.4e-101
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Kidney	rep_2	2.3e-129
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Kidney	rep_2	5.6e-85
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Kidney	rep_2	7.7e-108
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Kidney	rep_2	7.8e-96
Klk1b22	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Kidney	rep_2	4.6e-113
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Kidney	rep_2	2.6e-120
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Kidney	rep_2	1.4e-85
Klk1b22	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Klk1b22	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Kidney	rep_2	1.3e-133
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Kidney	rep_2	8.2e-110
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Kidney	rep_2	3.9e-99
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Kidney	rep_2	2.3e-91
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Kidney	rep_2	6.2e-146
Klk1b22	GOBP_Tube_Development	Mouse	Kidney	rep_2	1.2e-129
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Kidney	rep_2	2.1e-134
Klk1b22	GOBP_Vasculature_Development	Mouse	Kidney	rep_2	2.3e-129
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Liver	CN16-D1	4.3e-11
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Liver	CN16-D2	1.4e-10
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Liver	CN73-C1	4.0e-09
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Liver	CN73-C1	1.4e-08
Klk1b22	GOBP_Antibacterial_Peptide_Production	Mouse	Liver	rep_15	1.4e-40
Klk1b22	GOBP_Antimicrobial_Peptide_Production	Mouse	Liver	rep_15	1.4e-40
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Liver	rep_16	2.5e-24
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Liver	rep_16	1.1e-23
Klk1b22	GOBP_Defense_Response	Mouse	Liver	rep_16	8.0e-16
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Liver	rep_16	9.7e-26
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Liver	rep_16	1.8e-13
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Liver	rep_16	5.1e-08
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Liver	rep_16	6.6e-21
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Liver	rep_16	2.2e-07
Klk1b22	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Klk1b22	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Liver	rep_16	2.3e-07
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Liver	rep_16	9.5e-13
Klk1b22	GOBP_Zymogen_Activation	Mouse	Liver	rep_16	1.2e-18
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Lymph	MS-1	6.4e-13
Klk1b22	GOBP_Antibacterial_Humoral_Response	Mouse	Lymph	MS-1	3.5e-17
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Lymph	MS-1	7.0e-10
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Lymph	MS-1	3.6e-10
Klk1b22	GOBP_Cellular_Component_Disassembly	Mouse	Lymph	MS-1	2.4e-16
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Lymph	MS-1	1.6e-11
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Lymph	MS-1	3.9e-08
Klk1b22	GOBP_Defense_Response	Mouse	Lymph	MS-1	8.6e-18
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Lymph	MS-1	3.2e-17
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Lymph	MS-1	6.7e-20
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lymph	MS-1	6.5e-12
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Lymph	MS-1	1.2e-12
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Lymph	MS-1	3.4e-24
Klk1b22	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Lymph	MS-1	4.0e-14
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lymph	MS-1	6.6e-16
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Lymph	MS-1	6.6e-20
Klk1b22	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
Klk1b22	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Lymph	MS-1	2.4e-16
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Lymph	MS-1	2.5e-11
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Lymph	MS-1	7.2e-15
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Lymph	MS-1	7.2e-08
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Lymph	MS-1	5.0e-09
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Lymph	MS-1	6.2e-20
Klk1b22	GOBP_Tube_Development	Mouse	Lymph	MS-1	4.6e-09
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Lymph	MS-1	9.1e-10
Klk1b22	GOBP_Vasculature_Development	Mouse	Lymph	MS-1	3.0e-12
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Lung	rep_1	1.3e-11
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Lung	rep_1	1.3e-17
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Lung	rep_1	1.9e-11
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	rep_4	1.7e-08
Klk1b22	GOBP_Defense_Response	Mouse	Brain	HP_ad_rep7	5.6e-10
Klk1b22	GOBP_External_Encapsulating_Structure_Organization	Mouse	Brain	HP_ad_rep7	1.9e-11
Klk1b22	GOBP_Negative_Regulation_Of_Developmental_Process	Mouse	Brain	HP_ad_rep7	1.7e-11
Klk1b22	GOBP_Production_Of_Molecular_Mediator_Of_Immune_Response	Mouse	Brain	HP_ad_rep7	1.1e-12
Klk1b22	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Klk1b22	GOBP_Regulation_Of_Anatomical_Structure_Morphogenesis	Mouse	Brain	HP_ad_rep7	3.3e-08
Klk1b22	GOBP_Regulation_Of_Multicellular_Organismal_Development	Mouse	Brain	HP_ad_rep7	1.1e-08
Klk1b22	GOBP_Tube_Development	Mouse	Brain	HP_ad_rep7	2.0e-08
Klk1b22	GOBP_Antimicrobial_Humoral_Immune_Response_Mediated_By_Antimicrobial_Peptide	Mouse	Brain	HP_ad_rep8	1.6e-13
Klk1b22	GOBP_Defense_Response_To_Bacterium	Mouse	Brain	HP_adpolb_rep1	3.5e-10
Klk1b22	GOBP_Extracellular_Matrix_Disassembly	Mouse	Brain	HP_adpolb_rep1	6.8e-14
Klk1b22	GOBP_Humoral_Immune_Response	Mouse	Brain	HP_adpolb_rep1	2.0e-13
Klk1b22	GOBP_Negative_Regulation_Of_Vasculature_Development	Mouse	Brain	HP_adpolb_rep1	9.9e-07
Klk1b22	GOBP_Regulation_Of_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.1e-08
Klk1b22	GOBP_Regulation_Of_Systemic_Arterial_Blood_Pressure	Mouse	Brain	HP_adpolb_rep1	3.0e-08
Klk1b22	GOBP_Anatomical_Structure_Formation_Involved_In_Morphogenesis	Mouse	Brain	HP_polb_rep9	6.3e-08
Klk1b22	GOBP_Antimicrobial_Humoral_Response	Mouse	Brain	HP_polb_rep9	1.9e-08
Klk1b22	GOBP_Blood_Vessel_Morphogenesis	Mouse	Brain	HP_polb_rep9	1.0e-11
Klk1b22	GOBP_Cellular_Component_Disassembly	Mouse	Brain	HP_polb_rep9	3.4e-08
Klk1b22	GOBP_Circulatory_System_Development	Mouse	Brain	HP_polb_rep9	3.1e-09
Klk1b22	GOBP_Circulatory_System_Process	Mouse	Brain	HP_polb_rep9	5.3e-09
Klk1b22	GOBP_Defense_Response_To_Other_Organism	Mouse	Brain	HP_polb_rep9	2.1e-11
Klk1b22	GOBP_Negative_Regulation_Of_Multicellular_Organismal_Process	Mouse	Brain	HP_polb_rep9	1.8e-08
Klk1b22	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Klk1b22	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12
Klk1b22	GOBP_Regulation_Of_Vasculature_Development	Mouse	Brain	HP_polb_rep9	3.0e-08
Klk1b22	GOBP_Response_To_Bacterium	Mouse	Brain	HP_polb_rep9	4.4e-08
Klk1b22	GOBP_Tube_Morphogenesis	Mouse	Brain	HP_polb_rep9	4.0e-10
Klk1b22	GOBP_Vasculature_Development	Mouse	Brain	HP_polb_rep9	3.4e-10
Klk1b22	GOBP_Zymogen_Activation	Mouse	Brain	HP_polb_rep9	5.5e-16

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Klk1b22 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Klk1b22 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Klk1b22 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Klk1b22

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Klk1b22

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source