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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Entpd6 (spascer ID:12497)

Gene summary for Entpd6

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Entpd6
	Gene ID	12497
	Gene name	ectonucleoside triphosphate diphosphohydrolase 6
	Synonyms	2700026H11Rik\|Cd39l2\|NTPDase-6
	Cytomap	2\|2 G3
	Type of gene	protein-coding
	Description	ectonucleoside triphosphate diphosphohydrolase 6CD39 antigen-like 2NTPDase 6
	Modification date	20220424
	UniProtAcc	Q3U0P5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Entpd6	GO:0004382	guanosine-diphosphatase activity	21873635	Function
Entpd6	GO:0005794	Golgi apparatus	21873635	Component
Entpd6	GO:0009134	nucleoside diphosphate catabolic process	21873635	Process
Entpd6	GO:0016020	membrane	21873635	Component
Entpd6	GO:0017110	nucleoside-diphosphatase activity	21873635	Function
Entpd6	GO:0045134	uridine-diphosphatase activity	21873635	Function

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Spatial pattern events for Entpd6

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Entpd6	Mouse	Brain	S2	34413515	1.56e-15
Entpd6	Mouse	Brain	S3	34413515	1.64e-15
Entpd6	Mouse	Brain	S4	34413515	1.37e-15
Entpd6	Mouse	Brain	S6	34413515	1.46e-15
Entpd6	Mouse	Brain	S7	34413515	1.55e-15
Entpd6	Mouse	Brain	29A	32637622	2.23e-06
Entpd6	Mouse	Brain	rep_1	35141374	2.02e-15
Entpd6	Mouse	Brain	rep_2	35141374	1.69e-15
Entpd6	Mouse	Brain	rep_3	35141374	1.64e-15
Entpd6	Mouse	Brain	rep_4	35141374	1.57e-15
Entpd6	Mouse	Brain	rep_5	35141374	1.47e-15
Entpd6	Mouse	Brain	rep_6	35141374	1.73e-15
Entpd6	Mouse	Kidney	rep_1	34853151	2.88e-09
Entpd6	Mouse	Brain	rep_1	33469025	1.30e-15
Entpd6	Mouse	Brain	rep_1	35027729	1.66e-15
Entpd6	Mouse	Brain	rep_2	35027729	1.57e-15
Entpd6	Mouse	Brain	rep_3	35027729	1.32e-15
Entpd6	Mouse	Brain	rep_4	35027729	1.76e-15
Entpd6	Mouse	Brain	rep_5	35027729	1.46e-15
Entpd6	Mouse	Intestine	rep_4	35149721	4.03e-07
Entpd6	Mouse	Testicle	rep_6	34731600	8.60e-14
Entpd6	Mouse	Lymph	A1	0	8.39e-14
Entpd6	Mouse	Lymph	B1	0	4.93e-07
Entpd6	Mouse	Brain	rep_1	35210624	1.74e-15
Entpd6	Mouse	Brain	rep_2	35210624	1.74e-15
Entpd6	Mouse	Brain	rep_3	35210624	8.12e-12
Entpd6	Mouse	Brain	rep_5	35210624	4.66e-11
Entpd6	Mouse	Brain	rep_6	35210624	1.14e-11
Entpd6	Mouse	Brain	rep_7	35210624	2.31e-12

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Entpd6 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN34_C1	7.9e-06
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Spinal cord	L7CN34_C1	3.6e-06
Entpd6	GOBP_Dephosphorylation	Mouse	Spinal cord	L7CN45_C1	3.3e-07
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.3e-08
Entpd6	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Entpd6	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-07
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Spinal cord	L7CN45_C1	2.7e-07
Entpd6	GOBP_Response_To_Inorganic_Substance	Mouse	Spinal cord	L7CN45_C1	3.1e-08
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Spinal cord	L7CN45_C1	1.6e-08
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_17	1.4e-05
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_27	3.2e-10
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	rep_71	4.8e-05
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Brain	rep_71	3.2e-05
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_75	8.0e-05
Entpd6	GOBP_Dephosphorylation	Mouse	Brain	rep_1	1.5e-40
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_1	2.4e-23
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	1.9e-07
Entpd6	GOBP_Response_To_Inorganic_Substance	Mouse	Brain	rep_1	2.4e-10
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Brain	rep_1	6.0e-43
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.9e-170
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	rep_3	7.0e-63
Entpd6	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	rep_3	4.1e-202
Entpd6	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	rep_3	1.2e-230
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	rep_3	6.2e-102
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Brain	rep_5	1.7e-33
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Embryo	rep_6	5.3e-08
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-21
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	2.5e-41
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Embryo	rep_14	6.9e-28
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.3e-36
Entpd6	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-44
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Embryo	rep_14	2.9e-51
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Entpd6	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Embryo	rep_2	3.3e-45
Entpd6	GOBP_Response_To_Inorganic_Substance	Mouse	Embryo	rep_3	2.3e-136
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Entpd6	GOBP_Dephosphorylation	Mouse	Kidney	rep_2	1.4e-90
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	2.0e-16
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	5.7e-133
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-102
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Kidney	rep_2	3.9e-15
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Kidney	rep_2	1.6e-27
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Kidney	rep_2	3.3e-181
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Liver	CN16-D2	2.5e-12
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Liver	CN16-D2	2.1e-13
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Liver	CN16-E2	2.8e-07
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Liver	CN65-C1	5.9e-10
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Liver	rep_16	3.0e-15
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Liver	rep_16	9.6e-41
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	2.0e-22
Entpd6	GOBP_Dephosphorylation	Mouse	Lymph	MS-1	3.6e-12
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Entpd6	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-12
Entpd6	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.4e-09
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Lymph	MS-1	1.3e-10
Entpd6	GOBP_Response_To_Inorganic_Substance	Mouse	Lymph	MS-1	5.1e-09
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Lymph	MS-1	4.4e-11
Entpd6	GOBP_Response_To_Metal_Ion	Mouse	Lymph	MS-1	4.8e-09
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Lymph	PBS	4.2e-08
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Lung	rep_1	3.8e-11
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_4	5.6e-07
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_7	3.9e-26
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep3	6.3e-15
Entpd6	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	HP_ad_rep3	3.7e-11
Entpd6	GOBP_Dephosphorylation	Mouse	Brain	HP_ad_rep7	3.9e-08
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.8e-13
Entpd6	GOBP_Response_To_Calcium_Ion	Mouse	Brain	HP_ad_rep7	2.0e-09
Entpd6	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Entpd6	GOBP_Response_To_Magnesium_Ion	Mouse	Brain	HP_polb_rep1	3.8e-07
Entpd6	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Entpd6	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	3.2e-13
Entpd6	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-19
Entpd6	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-08
Entpd6	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.2e-08
Entpd6	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Entpd6	GOBP_Response_To_Inorganic_Substance	Mouse	Brain	HP_polb_rep9	2.6e-07
Entpd6	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Entpd6	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Entpd6 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Entpd6 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Entpd6 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Entpd6

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Entpd6

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Entpd6	C0028754	Obesity	1	CTD_human
Entpd6	C0036631	Seminoma	1	CTD_human