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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Entpd2 (spascer ID:12496)

Gene summary for Entpd2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Entpd2
	Gene ID	12496
	Gene name	ectonucleoside triphosphate diphosphohydrolase 2
	Synonyms	Cd39l1\|NTPDase2
	Cytomap	2\|2 A3
	Type of gene	protein-coding
	Description	ectonucleoside triphosphate diphosphohydrolase 2CD39 antigen-like 1NTPDase 2ecto-ATP diphosphohydrolase 2ecto-ATPDase 2ecto-ATPase 2
	Modification date	20220424
	UniProtAcc	O55026

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Entpd2	GO:0004382	guanosine-diphosphatase activity	21873635	Function
Entpd2	GO:0005886	plasma membrane	21873635	Component
Entpd2	GO:0009134	nucleoside diphosphate catabolic process	21873635	Process
Entpd2	GO:0016020	membrane	21873635	Component
Entpd2	GO:0017110	nucleoside-diphosphatase activity	21873635	Function
Entpd2	GO:0045134	uridine-diphosphatase activity	21873635	Function

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Spatial pattern events for Entpd2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Entpd2	Mouse	Brain	S2	34413515	1.32e-08
Entpd2	Mouse	Brain	S3	34413515	1.64e-15
Entpd2	Mouse	Brain	S4	34413515	1.78e-07
Entpd2	Mouse	Brain	S6	34413515	4.89e-09
Entpd2	Mouse	Brain	S7	34413515	1.68e-10
Entpd2	Mouse	Brain	rep_2	35141374	2.00e-07
Entpd2	Mouse	Brain	rep_4	35141374	1.57e-15
Entpd2	Mouse	Brain	rep_5	35141374	8.91e-11
Entpd2	Mouse	Brain	rep_6	35141374	1.52e-08
Entpd2	Mouse	Brain	rep_1	33469025	1.30e-15
Entpd2	Mouse	Liver	rep_21	35021063	4.60e-08
Entpd2	Mouse	Lymph	A1	0	1.98e-12
Entpd2	Mouse	Lymph	B1	0	1.65e-06
Entpd2	Mouse	Lung	rep_1	35290801	1.33e-12
Entpd2	Mouse	Lung	rep_4	35290801	5.10e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_2_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Brain_rep_1_H&E
Liver_rep_21_H&E
Lung_rep_1_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Entpd2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Entpd2	GOBP_Response_To_Wounding	Mouse	Spinal cord	CN94_E1	4.7e-06
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Spinal cord	L7bCN02_E1	3.1e-06
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN34_C1	7.9e-06
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Spinal cord	L7CN34_C1	3.6e-06
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Spinal cord	L7CN34_C1	1.8e-07
Entpd2	GOBP_Cell_Activation	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Spinal cord	L7CN45_C1	8.8e-08
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.5e-06
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.3e-08
Entpd2	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.3e-08
Entpd2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-07
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Entpd2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Spinal cord	L7CN45_C1	9.1e-06
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Entpd2	GOBP_Platelet_Activation	Mouse	Spinal cord	L7CN47_C1	2.0e-06
Entpd2	GOBP_Wound_Healing	Mouse	Spinal cord	L7CN47_C1	8.4e-07
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_9	1.1e-10
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_9	2.3e-05
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_17	1.4e-05
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_27	8.0e-06
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_27	3.2e-10
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	rep_71	4.8e-05
Entpd2	GOBP_Cell_Activation	Mouse	Brain	rep_72	4.6e-06
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_75	8.0e-05
Entpd2	GOBP_Cell_Activation	Mouse	Brain	rep_1	1.8e-07
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_1	4.5e-16
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_1	2.4e-23
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	1.9e-07
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	7.3e-22
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	5.2e-10
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.9e-170
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	rep_3	7.0e-63
Entpd2	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	rep_3	4.1e-202
Entpd2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	rep_3	1.2e-230
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	rep_3	6.2e-102
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Entpd2	GOBP_Platelet_Activation	Mouse	Brain	rep_3	1.1e-161
Entpd2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	rep_3	1.1e-62
Entpd2	GOBP_Response_To_Wounding	Mouse	Brain	rep_3	6.2e-112
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Entpd2	GOBP_Wound_Healing	Mouse	Brain	rep_3	6.2e-109
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	1.4e-21
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	2.5e-41
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Embryo	rep_14	6.9e-28
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.3e-36
Entpd2	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-44
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Embryo	rep_14	2.9e-51
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Entpd2	GOBP_Platelet_Activation	Mouse	Embryo	rep_14	2.4e-18
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Embryo	rep_14	1.0e-20
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Embryo	rep_14	6.2e-27
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Entpd2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Embryo	rep_2	3.3e-45
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Embryo	rep_3	0.0e+00
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	Nep	4.2e-26
Entpd2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Kidney	Nep	1.6e-16
Entpd2	GOBP_Response_To_Wounding	Mouse	Kidney	Nep	1.6e-16
Entpd2	GOBP_Wound_Healing	Mouse	Kidney	Nep	1.6e-16
Entpd2	GOBP_Cell_Activation	Mouse	Kidney	rep_2	5.1e-83
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Kidney	rep_2	3.0e-37
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	2.0e-16
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	5.7e-133
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-102
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Kidney	rep_2	3.9e-15
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Entpd2	GOBP_Response_To_Wounding	Mouse	Kidney	rep_2	2.1e-60
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Entpd2	GOBP_Wound_Healing	Mouse	Kidney	rep_2	6.5e-45
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Liver	CN16-D2	2.5e-12
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Liver	CN16-D2	1.4e-09
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Liver	CN65-C1	5.9e-10
Entpd2	GOBP_Platelet_Activation	Mouse	Liver	CN73-C1	1.6e-11
Entpd2	GOBP_Response_To_Wounding	Mouse	Liver	CN73-C1	1.1e-07
Entpd2	GOBP_Wound_Healing	Mouse	Liver	CN73-C1	1.1e-08
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Liver	rep_15	4.7e-28
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Liver	rep_15	2.0e-18
Entpd2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Liver	rep_16	6.1e-20
Entpd2	GOBP_Response_To_Wounding	Mouse	Liver	rep_16	1.3e-13
Entpd2	GOBP_Wound_Healing	Mouse	Liver	rep_16	3.5e-11
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	2.0e-22
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	6.6e-05
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_1	4.7e-14
Entpd2	GOBP_Cell_Activation	Mouse	Lymph	MS-1	1.6e-18
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Lymph	MS-1	1.8e-08
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Entpd2	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.0e-12
Entpd2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Lymph	MS-1	2.4e-09
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Lymph	PBS	4.2e-08
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	rep_4	1.7e-17
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_4	5.6e-07
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_7	3.9e-26
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	rep_7	1.0e-16
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep3	6.3e-15
Entpd2	GOBP_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	HP_ad_rep3	3.7e-11
Entpd2	GOBP_Purine_Nucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	HP_ad_rep3	8.8e-30
Entpd2	GOBP_Ribonucleoside_Diphosphate_Catabolic_Process	Mouse	Brain	HP_ad_rep3	6.1e-13
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.8e-13
Entpd2	GOBP_Response_To_Wounding	Mouse	Brain	HP_ad_rep7	4.3e-07
Entpd2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Entpd2	GOBP_Cell_Activation	Mouse	Brain	HP_polb_rep9	1.5e-08
Entpd2	GOBP_G_Protein_Coupled_Receptor_Signaling_Pathway	Mouse	Brain	HP_polb_rep9	6.4e-16
Entpd2	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Entpd2	GOBP_Nucleoside_Diphosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	3.2e-13
Entpd2	GOBP_Nucleoside_Phosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-19
Entpd2	GOBP_Organic_Cyclic_Compound_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.6e-08
Entpd2	GOBP_Organophosphate_Catabolic_Process	Mouse	Brain	HP_polb_rep9	1.2e-08
Entpd2	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Entpd2	GOBP_Platelet_Activation	Mouse	Brain	HP_polb_rep9	1.1e-07
Entpd2	GOBP_Regulation_Of_Body_Fluid_Levels	Mouse	Brain	HP_polb_rep9	2.9e-10
Entpd2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Entpd2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Entpd2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Entpd2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Entpd2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Entpd2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Entpd2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source