Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Cast (spascer ID:12380)

Gene summary for Cast

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Cast
	Gene ID	12380
	Gene name	calpastatin
	Synonyms	-
	Cytomap	13\|13 C1
	Type of gene	protein-coding
	Description	calpastatincalpain inhibitorcalpastatin type III
	Modification date	20220424
	UniProtAcc	P51125

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Cast	GO:0005737	cytoplasm	21873635	Component
Cast	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity	21873635	Function
Cast	GO:0097340	inhibition of cysteine-type endopeptidase activity	21873635	Process

Top

Spatial pattern events for Cast

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Cast	Mouse	Brain	S4	34413515	1.38e-10
Cast	Mouse	Brain	S6	34413515	2.19e-06
Cast	Mouse	Brain	rep_4	35141374	2.01e-09
Cast	Mouse	Kidney	CLP	34003797	6.92e-15
Cast	Mouse	Kidney	IRI	34003797	2.29e-15
Cast	Mouse	Kidney	Sham	34003797	3.59e-07
Cast	Mouse	Kidney	rep_1	34853151	7.47e-06
Cast	Mouse	Intestine	rep_2	35149721	3.44e-15
Cast	Mouse	Intestine	rep_3	35149721	3.25e-15
Cast	Mouse	Intestine	rep_4	35149721	7.23e-15
Cast	Mouse	Testicle	rep_4	34731600	2.08e-14

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E

Top

Spatial pattern pathway has Cast envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Cast	GOBP_Negative_Regulation_Of_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Spinal cord	CN81_E1	4.4e-08
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Spinal cord	CN94_E1	4.6e-07
Cast	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Spinal cord	CN94_E1	2.4e-06
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Spinal cord	L7bCN01_D2	8.6e-07
Cast	GOBP_Cell_Junction_Organization	Mouse	Spinal cord	L7bCN02_E1	4.0e-06
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Spinal cord	L7bCN02_E1	2.6e-07
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	6.7e-07
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Spinal cord	L7CN45_C1	2.0e-06
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	2.5e-08
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Spinal cord	L7CN45_C1	2.8e-06
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Cast	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Cast	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Spinal cord	L7CN45_C1	2.3e-07
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Spinal cord	L7CN45_C1	8.0e-07
Cast	GOBP_Synapse_Organization	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Cast	GOBP_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Spinal cord	L7CN45_C1	3.2e-06
Cast	GOBP_Zymogen_Inhibition	Mouse	Spinal cord	L7CN47_D1	4.2e-06
Cast	GOBP_Regulation_Of_Protein_Maturation	Mouse	Spinal cord	L7CN97_E2	8.2e-07
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Spinal cord	L8CN11_D2	2.5e-11
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	rep_17	4.1e-07
Cast	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_27	5.8e-05
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_27	8.1e-06
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_27	4.7e-05
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_27	1.2e-06
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	rep_27	6.3e-05
Cast	GOBP_Synapse_Organization	Mouse	Brain	rep_27	6.2e-06
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Brain	rep_61	2.0e-05
Cast	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_1	1.5e-30
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	rep_1	1.0e-08
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Brain	rep_1	3.9e-40
Cast	GOBP_Synapse_Organization	Mouse	Brain	rep_1	3.8e-27
Cast	GOBP_Zymogen_Inhibition	Mouse	Brain	rep_1	4.3e-08
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	rep_3	2.6e-167
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	rep_3	5.2e-181
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Brain	rep_3	2.5e-150
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	rep_3	8.5e-19
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	rep_3	1.1e-139
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	3.5e-163
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Brain	rep_3	2.0e-154
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Brain	rep_3	1.8e-119
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	rep_3	5.5e-184
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Brain	rep_3	1.6e-155
Cast	GOBP_Negative_Regulation_Of_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Brain	rep_3	2.0e-14
Cast	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Cast	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
Cast	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	rep_3	7.6e-107
Cast	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Brain	rep_3	1.1e-120
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	rep_3	8.9e-131
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	rep_3	1.4e-120
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Brain	rep_3	9.5e-157
Cast	GOBP_Regulation_Of_Protein_Maturation	Mouse	Brain	rep_3	2.2e-151
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Brain	rep_3	6.6e-161
Cast	GOBP_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Brain	rep_3	5.4e-66
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Brain	rep_7	2.9e-51
Cast	GOBP_Zymogen_Inhibition	Mouse	Embryo	rep_6	6.5e-16
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	7.1e-33
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Embryo	rep_14	2.7e-43
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	6.6e-27
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	4.4e-26
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Embryo	rep_14	4.7e-19
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Embryo	rep_14	2.2e-46
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Embryo	rep_14	6.7e-38
Cast	GOBP_Negative_Regulation_Of_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	3.1e-31
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Embryo	rep_14	2.8e-24
Cast	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Cast	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
Cast	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Embryo	rep_14	5.2e-45
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	9.3e-42
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_14	8.5e-07
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Embryo	rep_14	6.4e-29
Cast	GOBP_Regulation_Of_Protein_Maturation	Mouse	Embryo	rep_14	6.5e-65
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Embryo	rep_14	3.6e-20
Cast	GOBP_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Embryo	rep_14	2.8e-28
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Embryo	rep_1	2.5e-32
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Embryo	rep_1	0.0e+00
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Embryo	rep_1	9.4e-07
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Embryo	rep_1	4.6e-17
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Embryo	rep_1	4.6e-17
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Embryo	rep_1	8.4e-30
Cast	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Embryo	rep_1	5.8e-37
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Embryo	rep_3	1.9e-126
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Embryo	rep_4	8.1e-31
Cast	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Cast	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	Nep	8.3e-23
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	Nep	4.6e-22
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Kidney	Nep	4.2e-26
Cast	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	Nep	1.3e-36
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Kidney	Nep	5.6e-37
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Kidney	Nep	4.3e-38
Cast	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
Cast	GOBP_Cell_Junction_Organization	Mouse	Kidney	rep_2	6.2e-52
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Kidney	rep_2	5.5e-56
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Kidney	rep_2	5.2e-90
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Kidney	rep_2	4.6e-36
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Kidney	rep_2	8.6e-43
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Kidney	rep_2	1.0e-19
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	5.7e-63
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Kidney	rep_2	2.5e-99
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Kidney	rep_2	3.5e-56
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Kidney	rep_2	5.8e-11
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Kidney	rep_2	1.5e-72
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Kidney	rep_2	4.3e-45
Cast	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Cast	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Cast	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Kidney	rep_2	5.6e-70
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Kidney	rep_2	1.2e-43
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Kidney	rep_2	1.4e-60
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Kidney	rep_2	5.7e-75
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Kidney	rep_2	4.3e-62
Cast	GOBP_Synapse_Organization	Mouse	Kidney	rep_2	3.0e-45
Cast	GOBP_Zymogen_Inhibition	Mouse	Kidney	rep_2	3.5e-07
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Liver	CN73-C1	9.9e-07
Cast	GOBP_Cell_Junction_Organization	Mouse	Liver	rep_16	1.6e-07
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Liver	rep_16	1.0e-10
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Liver	rep_16	2.7e-09
Cast	GOBP_Negative_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Liver	rep_16	3.1e-15
Cast	GOBP_Negative_Regulation_Of_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Liver	rep_16	1.6e-11
Cast	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Cast	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Liver	rep_16	2.0e-13
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Liver	rep_16	2.7e-18
Cast	GOBP_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Liver	rep_16	2.5e-28
Cast	GOBP_Zymogen_Inhibition	Mouse	Liver	rep_16	3.1e-14
Cast	GOBP_Zymogen_Inhibition	Mouse	Brain	rep_1	2.5e-19
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Intestine	rep_2	4.0e-08
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Lymph	MS-1	2.4e-10
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Lymph	MS-1	2.2e-13
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Lymph	MS-1	3.9e-13
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Lymph	MS-1	2.6e-10
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lymph	MS-1	6.3e-11
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	4.3e-09
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lymph	MS-1	6.9e-11
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Lymph	MS-1	8.0e-07
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Lymph	MS-1	2.2e-07
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-11
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Lymph	MS-1	2.8e-11
Cast	GOBP_Negative_Regulation_Of_Type_B_Pancreatic_Cell_Apoptotic_Process	Mouse	Lymph	MS-1	2.7e-07
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Lymph	MS-1	7.6e-10
Cast	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
Cast	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Lymph	MS-1	1.9e-12
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Lymph	MS-1	5.3e-10
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Lymph	MS-1	1.9e-08
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Lymph	MS-1	4.0e-08
Cast	GOBP_Regulation_Of_Protein_Maturation	Mouse	Lymph	MS-1	1.1e-12
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Lymph	MS-1	7.3e-10
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Lung	rep_1	6.3e-10
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Lung	rep_1	4.5e-23
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Lung	rep_1	9.4e-15
Cast	GOBP_Cell_Junction_Organization	Mouse	Brain	rep_4	3.7e-07
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Brain	rep_4	1.0e-86
Cast	GOBP_Synapse_Organization	Mouse	Brain	rep_4	3.8e-17
Cast	GOBP_Zymogen_Inhibition	Mouse	Brain	HP_ad_rep3	3.0e-29
Cast	GOBP_Cell_Junction_Organization	Mouse	Brain	HP_ad_rep7	2.9e-10
Cast	GOBP_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	HP_ad_rep7	6.1e-08
Cast	GOBP_Negative_Regulation_Of_Catalytic_Activity	Mouse	Brain	HP_ad_rep7	4.0e-09
Cast	GOBP_Negative_Regulation_Of_Gene_Expression	Mouse	Brain	HP_ad_rep7	2.1e-08
Cast	GOBP_Negative_Regulation_Of_Molecular_Function	Mouse	Brain	HP_ad_rep7	3.4e-10
Cast	GOBP_Negative_Regulation_Of_Protein_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.1e-09
Cast	GOBP_Presynaptic_Active_Zone_Organization	Mouse	Brain	HP_ad_rep7	7.0e-08
Cast	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Cast	GOBP_Regulation_Of_Cell_Death	Mouse	Brain	HP_ad_rep7	1.6e-07
Cast	GOBP_Regulation_Of_Protein_Maturation	Mouse	Brain	HP_ad_rep7	3.0e-09
Cast	GOBP_Synapse_Organization	Mouse	Brain	HP_ad_rep7	7.3e-08
Cast	GOBP_Negative_Regulation_Of_Cell_Death	Mouse	Brain	HP_polb_rep9	9.2e-10
Cast	GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Brain	HP_polb_rep9	4.1e-10
Cast	GOBP_Negative_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	7.1e-13
Cast	GOBP_Negative_Regulation_Of_Peptidase_Activity	Mouse	Brain	HP_polb_rep9	4.7e-12
Cast	GOBP_Negative_Regulation_Of_Protein_Maturation	Mouse	Brain	HP_polb_rep9	8.2e-08
Cast	GOBP_Negative_Regulation_Of_Proteolysis	Mouse	Brain	HP_polb_rep9	4.4e-09
Cast	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Cast	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12
Cast	GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_Activity	Mouse	Brain	HP_polb_rep9	3.6e-09
Cast	GOBP_Regulation_Of_Epithelial_Cell_Apoptotic_Process	Mouse	Brain	HP_polb_rep9	2.2e-07
Cast	GOBP_Regulation_Of_Hydrolase_Activity	Mouse	Brain	HP_polb_rep9	6.0e-09
Cast	GOBP_Regulation_Of_Peptidase_Activity	Mouse	Brain	HP_polb_rep9	5.2e-09
Cast	GOBP_Regulation_Of_Proteolysis	Mouse	Brain	HP_polb_rep9	1.5e-07

Top

Cast function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

Cast function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for Cast envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for Cast

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for Cast

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Cast	C0027540	Necrosis	1	CTD_human
Cast	C0162557	Liver Failure, Acute	1	CTD_human
Cast	C4225381	PEELING SKIN WITH LEUKONYCHIA, ACRAL PUNCTATE KERATOSES, CHEILITIS, AND KNUCKLE PADS	1	CTD_human;GENOMICS_ENGLAND;ORPHANET