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Spatial pattern gene: Capn6 (spascer ID:12338) |
Gene summary for Capn6 |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Capn6 | Gene ID | 12338 |
| Gene name | calpain 6 |
| Synonyms | - |
| Cytomap | X|X F2 |
| Type of gene | protein-coding |
| Description | calpain-6 |
| Modification date | 20220424 |
| UniProtAcc | O35646 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| Capn6 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity | 21873635 | Function |
| Capn6 | GO:0005737 | cytoplasm | 21873635 | Component |
| Capn6 | GO:0006508 | proteolysis | 21873635 | Process |
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Spatial pattern events for Capn6 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Capn6 | Mouse | Embryo | 1D | 34210887 | 2.08e-08 |
| Capn6 | Mouse | Embryo | 1E | 34210887 | 7.50e-15 |
| Capn6 | Mouse | Embryo | 1F | 34210887 | 2.30e-14 |
| Capn6 | Mouse | Embryo | 1G | 34210887 | 6.91e-14 |
| Capn6 | Mouse | Embryo | 2H | 34210887 | 1.72e-14 |
| Capn6 | Mouse | Embryo | 3D | 34210887 | 2.48e-10 |
| Capn6 | Mouse | Embryo | 3F | 34210887 | 2.30e-12 |
| Capn6 | Mouse | Embryo | 3G | 34210887 | 8.80e-15 |
| Capn6 | Mouse | Embryo | 3H | 34210887 | 1.95e-06 |
| Capn6 | Mouse | Embryo | 4A | 34210887 | 7.53e-14 |
| Capn6 | Mouse | Embryo | 4C | 34210887 | 4.64e-14 |
| Capn6 | Mouse | Embryo | 4D | 34210887 | 1.36e-14 |
| Capn6 | Mouse | Embryo | 4E | 34210887 | 4.53e-15 |
| Capn6 | Mouse | Embryo | rep_2 | 33188776 | 1.37e-14 |
| Capn6 | Mouse | Embryo | rep_3 | 33188776 | 8.85e-12 |
| Capn6 | Mouse | Embryo | rep_4 | 33188776 | 5.08e-15 |
| Capn6 | Mouse | Embryo | rep_5 | 33188776 | 7.96e-10 |
| Capn6 | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Capn6 | Mouse | Kidney | rep_1 | 33976190 | 6.40e-08 |
| Capn6 | Mouse | Kidney | rep_2 | 33976190 | 8.71e-06 |
| Capn6 | Mouse | Testicle | rep_4 | 34731600 | 3.38e-15 |
| Capn6 | Mouse | Testicle | rep_6 | 34731600 | 7.91e-15 |
| Capn6 | Mouse | Lymph | A1 | 0 | 1.44e-13 |
| Capn6 | Mouse | Lymph | B1 | 0 | 9.76e-13 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Kidney_rep_1_H&E  |  |
Kidney_rep_2_H&E  |  |
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Spatial pattern pathway has Capn6 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Capn6 | GOBP_Microtubule_Based_Process | Mouse | Spinal cord | CN94_E1 | 2.4e-06 |
| Capn6 | GOBP_Cytoskeleton_Organization | Mouse | Spinal cord | L7bCN02_E1 | 8.3e-06 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Brain | rep_27 | 5.5e-06 |
| Capn6 | GOBP_Cytoskeleton_Organization | Mouse | Brain | rep_1 | 1.1e-11 |
| Capn6 | GOBP_Microtubule_Based_Process | Mouse | Brain | rep_1 | 1.6e-07 |
| Capn6 | GOBP_Regulation_Of_Cytoskeleton_Organization | Mouse | Brain | rep_1 | 1.1e-40 |
| Capn6 | GOBP_Regulation_Of_Organelle_Organization | Mouse | Brain | rep_1 | 7.9e-20 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Brain | rep_3 | 3.9e-115 |
| Capn6 | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Brain | rep_3 | 8.5e-140 |
| Capn6 | GOBP_Regulation_Of_Cytoskeleton_Organization | Mouse | Embryo | rep_1 | 2.6e-63 |
| Capn6 | GOBP_Regulation_Of_Organelle_Organization | Mouse | Embryo | rep_3 | 1.3e-27 |
| Capn6 | GOBP_Cytoskeleton_Organization | Mouse | Kidney | rep_2 | 1.5e-44 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Kidney | rep_2 | 3.8e-46 |
| Capn6 | GOBP_Regulation_Of_Cytoskeleton_Organization | Mouse | Kidney | rep_2 | 1.8e-22 |
| Capn6 | GOBP_Regulation_Of_Organelle_Organization | Mouse | Kidney | rep_2 | 6.7e-77 |
| Capn6 | GOBP_Microtubule_Based_Process | Mouse | Liver | CN16-D2 | 1.8e-11 |
| Capn6 | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Liver | CN16-D2 | 2.8e-10 |
| Capn6 | GOBP_Cytoskeleton_Organization | Mouse | Lymph | MS-1 | 1.8e-13 |
| Capn6 | GOBP_Microtubule_Based_Process | Mouse | Lymph | MS-1 | 1.5e-08 |
| Capn6 | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Lymph | MS-1 | 7.6e-07 |
| Capn6 | GOBP_Regulation_Of_Cytoskeleton_Organization | Mouse | Lymph | MS-1 | 8.4e-09 |
| Capn6 | GOBP_Regulation_Of_Organelle_Organization | Mouse | Lymph | MS-1 | 1.4e-10 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Lung | rep_1 | 9.2e-16 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Brain | rep_4 | 1.1e-31 |
| Capn6 | GOBP_Cytoskeleton_Organization | Mouse | Brain | HP_ad_rep7 | 5.3e-08 |
| Capn6 | GOBP_Microtubule_Based_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-10 |
| Capn6 | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Brain | HP_ad_rep7 | 3.8e-13 |
| Capn6 | GOBP_Regulation_Of_Organelle_Organization | Mouse | Brain | HP_ad_rep7 | 8.1e-07 |
| Capn6 | GOBP_Microtubule_Bundle_Formation | Mouse | Brain | HP_adpolb_rep1 | 4.0e-08 |
| Capn6 | GOBP_Regulation_Of_Cytoskeleton_Organization | Mouse | Brain | HP_polb_rep9 | 1.1e-07 |
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Capn6 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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Capn6 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for Capn6 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for Capn6 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for Capn6 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
