|
||||||
|
 | |
| |
| |
| |
| |
| |
| |
|
Spatial pattern gene: Aspm (spascer ID:12316) |
Gene summary for Aspm |
 Gene summary |
| Gene information | |
| Species | Mouse | Gene symbol | Aspm | Gene ID | 12316 |
| Gene name | abnormal spindle microtubule assembly |
| Synonyms | Calmbp1|D330028K02Rik|MCPH5|Sha1 |
| Cytomap | 1|1 F |
| Type of gene | protein-coding |
| Description | abnormal spindle-like microcephaly-associated protein homologasp (abnormal spindle)-like, microcephaly associatedcalmodulin-binding protein 1calmodulin-binding protein Sha1spindle and hydroxyurea checkpoint abnormal protein |
| Modification date | 20220424 |
| UniProtAcc | Q8CJ27 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
Top |
Spatial pattern events for Aspm |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| Aspm | Mouse | Embryo | 4E | 34210887 | 2.19e-08 |
| Aspm | Mouse | Embryo | rep_2 | 33188776 | 3.50e-14 |
| Aspm | Mouse | Embryo | rep_3 | 33188776 | 1.13e-14 |
| Aspm | Mouse | Embryo | rep_5 | 33188776 | 6.15e-10 |
| Aspm | Mouse | Embryo | rep_7 | 33188776 | 2.25e-11 |
| Aspm | Mouse | Embryo | rep_12 | 33188776 | 3.52e-12 |
| Aspm | Mouse | Embryo | rep_13 | 33188776 | 4.49e-15 |
| Aspm | Mouse | Lymph | A1 | 0 | 3.29e-15 |
| Aspm | Mouse | Lymph | B1 | 0 | 1.41e-13 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Top |
Spatial pattern pathway has Aspm envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| Aspm | GOBP_Cell_Cycle | Mouse | Spinal cord | CN94_E1 | 1.1e-06 |
| Aspm | GOBP_Cell_Cycle_Process | Mouse | Spinal cord | CN94_E1 | 3.8e-06 |
| Aspm | GOBP_Microtubule_Based_Process | Mouse | Spinal cord | CN94_E1 | 2.4e-06 |
| Aspm | GOBP_Cytoskeleton_Organization | Mouse | Spinal cord | L7bCN02_E1 | 8.3e-06 |
| Aspm | GOBP_Cell_Division | Mouse | Spinal cord | L7CN45_C1 | 2.6e-06 |
| Aspm | GOBP_Organelle_Localization | Mouse | Spinal cord | L7CN45_C1 | 1.4e-08 |
| Aspm | GOBP_Spindle_Localization | Mouse | Spinal cord | L7CN45_C1 | 6.6e-09 |
| Aspm | GOBP_Cell_Cycle | Mouse | Brain | rep_27 | 8.4e-07 |
| Aspm | GOBP_Cell_Division | Mouse | Brain | rep_27 | 3.6e-05 |
| Aspm | GOBP_Spindle_Organization | Mouse | Brain | rep_41 | 1.3e-05 |
| Aspm | GOBP_Cell_Cycle | Mouse | Brain | rep_1 | 7.0e-10 |
| Aspm | GOBP_Cell_Cycle_Process | Mouse | Brain | rep_1 | 6.7e-14 |
| Aspm | GOBP_Cell_Division | Mouse | Brain | rep_1 | 9.7e-23 |
| Aspm | GOBP_Cytoskeleton_Organization | Mouse | Brain | rep_1 | 1.1e-11 |
| Aspm | GOBP_Microtubule_Based_Process | Mouse | Brain | rep_1 | 1.6e-07 |
| Aspm | GOBP_Organelle_Localization | Mouse | Brain | rep_1 | 1.6e-45 |
| Aspm | GOBP_Spindle_Localization | Mouse | Brain | rep_1 | 1.6e-28 |
| Aspm | GOBP_Spindle_Organization | Mouse | Brain | rep_1 | 3.4e-10 |
| Aspm | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Brain | rep_3 | 8.5e-140 |
| Aspm | GOBP_Cell_Division | Mouse | Embryo | rep_1 | 0.0e+00 |
| Aspm | GOBP_Cell_Cycle | Mouse | Kidney | rep_2 | 1.0e-24 |
| Aspm | GOBP_Cell_Cycle_Process | Mouse | Kidney | rep_2 | 3.0e-21 |
| Aspm | GOBP_Cell_Division | Mouse | Kidney | rep_2 | 5.3e-77 |
| Aspm | GOBP_Cytoskeleton_Organization | Mouse | Kidney | rep_2 | 1.5e-44 |
| Aspm | GOBP_Organelle_Localization | Mouse | Kidney | rep_2 | 2.9e-72 |
| Aspm | GOBP_Spindle_Localization | Mouse | Kidney | rep_2 | 2.2e-58 |
| Aspm | GOBP_Microtubule_Based_Process | Mouse | Liver | CN16-D2 | 1.8e-11 |
| Aspm | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Liver | CN16-D2 | 2.8e-10 |
| Aspm | GOBP_Spindle_Organization | Mouse | Liver | CN16-D2 | 3.8e-08 |
| Aspm | GOBP_Organelle_Localization | Mouse | Liver | rep_16 | 2.2e-21 |
| Aspm | GOBP_Cell_Cycle | Mouse | Lymph | MS-1 | 1.3e-07 |
| Aspm | GOBP_Cytoskeleton_Organization | Mouse | Lymph | MS-1 | 1.8e-13 |
| Aspm | GOBP_Microtubule_Based_Process | Mouse | Lymph | MS-1 | 1.5e-08 |
| Aspm | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Lymph | MS-1 | 7.6e-07 |
| Aspm | GOBP_Organelle_Localization | Mouse | Brain | rep_4 | 3.3e-19 |
| Aspm | GOBP_Cell_Cycle | Mouse | Brain | HP_ad_rep7 | 6.6e-08 |
| Aspm | GOBP_Cell_Cycle_Process | Mouse | Brain | HP_ad_rep7 | 1.7e-09 |
| Aspm | GOBP_Cell_Division | Mouse | Brain | HP_ad_rep7 | 2.6e-09 |
| Aspm | GOBP_Cytoskeleton_Organization | Mouse | Brain | HP_ad_rep7 | 5.3e-08 |
| Aspm | GOBP_Microtubule_Based_Process | Mouse | Brain | HP_ad_rep7 | 2.8e-10 |
| Aspm | GOBP_Microtubule_Cytoskeleton_Organization | Mouse | Brain | HP_ad_rep7 | 3.8e-13 |
| Aspm | GOBP_Spindle_Organization | Mouse | Brain | HP_ad_rep7 | 1.6e-12 |
| Aspm | GOBP_Organelle_Localization | Mouse | Brain | HP_polb_rep9 | 1.7e-09 |
Top |
Aspm function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
Top |
Aspm function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
Top |
Transcription factor for Aspm envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
Top |
Related Drugs for Aspm |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for Aspm |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| Aspm | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Aspm | C0032460 | Polycystic Ovary Syndrome | 1 | CTD_human |
| Aspm | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| Aspm | C0220636 | Malignant neoplasm of salivary gland | 1 | CTD_human |
| Aspm | C1136382 | Sclerocystic Ovaries | 1 | CTD_human |
| Aspm | C1837501 | Microcephaly, Primary Autosomal Recessive, 5 | 1 | CTD_human;GENOMICS_ENGLAND |
| Aspm | C2239176 | Liver carcinoma | 1 | CTD_human |
