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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Aqp8 (spascer ID:11833)

Gene summary for Aqp8

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Aqp8
	Gene ID	11833
	Gene name	aquaporin 8
	Synonyms	AI255744\|AQP-8
	Cytomap	7 F3\|7 67.42 cM
	Type of gene	protein-coding
	Description	aquaporin-8
	Modification date	20220424
	UniProtAcc	P56404

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Aqp8	GO:0005886	plasma membrane	21873635	Component
Aqp8	GO:0006833	water transport	21873635	Process
Aqp8	GO:0015250	water channel activity	21873635	Function

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Spatial pattern events for Aqp8

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Aqp8	Mouse	Embryo	rep_1	34489600	3.74e-16
Aqp8	Mouse	Embryo	rep_2	34489600	4.14e-16
Aqp8	Mouse	Embryo	rep_3	34489600	4.04e-16
Aqp8	Mouse	Embryo	rep_4	34489600	3.67e-16
Aqp8	Mouse	Embryo	rep_5	34489600	4.08e-16
Aqp8	Mouse	Liver	rep_14	35021063	5.47e-10
Aqp8	Mouse	Liver	rep_17	35021063	6.49e-10
Aqp8	Mouse	Liver	rep_18	35021063	1.47e-06
Aqp8	Mouse	Liver	rep_19	35021063	8.86e-09
Aqp8	Mouse	Liver	rep_20	35021063	9.91e-15
Aqp8	Mouse	Liver	rep_21	35021063	8.03e-15
Aqp8	Mouse	Liver	rep_22	35021063	1.07e-14
Aqp8	Mouse	Intestine	rep_1	35149721	6.08e-15
Aqp8	Mouse	Intestine	rep_2	35149721	3.44e-15
Aqp8	Mouse	Intestine	rep_3	35149721	3.25e-15
Aqp8	Mouse	Intestine	rep_4	35149721	2.30e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_14_H&E
Liver_rep_17_H&E
Liver_rep_18_H&E
Liver_rep_19_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E

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Spatial pattern pathway has Aqp8 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	4.1e-07
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Spinal cord	CN94_E1	2.2e-06
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Spinal cord	CN94_E1	5.6e-06
Aqp8	GOBP_Fluid_Transport	Mouse	Spinal cord	L7bCN05_D1	2.1e-06
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Spinal cord	L7CN45_C1	3.7e-09
Aqp8	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Spinal cord	L7CN45_C1	3.2e-07
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	1.6e-07
Aqp8	GOBP_Response_To_Camp	Mouse	Spinal cord	L7CN45_C1	2.3e-06
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Spinal cord	L7CN45_C1	6.3e-07
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Aqp8	GOBP_Transmembrane_Transport	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Aqp8	GOBP_Water_Transport	Mouse	Brain	rep_9	1.2e-08
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Brain	rep_71	4.8e-05
Aqp8	GOBP_Response_To_Camp	Mouse	Brain	rep_71	7.2e-05
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	rep_1	1.5e-10
Aqp8	GOBP_Transmembrane_Transport	Mouse	Brain	rep_1	3.1e-23
Aqp8	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Brain	rep_3	1.3e-60
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	8.2e-81
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	rep_3	6.4e-96
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	rep_3	2.5e-82
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	rep_3	3.4e-98
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	rep_3	6.3e-92
Aqp8	GOBP_Fluid_Transport	Mouse	Brain	rep_4	5.0e-10
Aqp8	GOBP_Water_Transport	Mouse	Embryo	rep_5	2.0e-22
Aqp8	GOBP_Response_To_Camp	Mouse	Embryo	rep_6	1.6e-23
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Embryo	rep_14	4.4e-41
Aqp8	GOBP_Fluid_Transport	Mouse	Embryo	rep_14	1.3e-40
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Embryo	rep_14	2.3e-25
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Embryo	rep_1	2.5e-19
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Embryo	rep_3	0.0e+00
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Embryo	rep_3	0.0e+00
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Embryo	rep_6	2.0e-17
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	Nep	6.3e-23
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	Nep	6.8e-28
Aqp8	GOBP_Transmembrane_Transport	Mouse	Kidney	Nep	4.2e-26
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Kidney	rep_2	2.9e-38
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	5.2e-82
Aqp8	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Kidney	rep_2	2.5e-50
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	4.5e-89
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Kidney	rep_2	1.1e-44
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Kidney	rep_2	1.0e-56
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Kidney	rep_2	1.3e-60
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Kidney	rep_2	6.6e-112
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Kidney	rep_2	2.5e-14
Aqp8	GOBP_Transmembrane_Transport	Mouse	Kidney	rep_2	2.7e-23
Aqp8	GOBP_Fluid_Transport	Mouse	Liver	CN16-D1	3.4e-09
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Liver	CN16-D1	5.5e-07
Aqp8	GOBP_Water_Transport	Mouse	Liver	CN16-D1	5.8e-20
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Liver	rep_16	1.0e-14
Aqp8	GOBP_Transmembrane_Transport	Mouse	Liver	rep_16	1.4e-13
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Lymph	MS-1	4.9e-20
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	7.5e-11
Aqp8	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Lymph	MS-1	4.3e-09
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	7.5e-11
Aqp8	GOBP_Fluid_Transport	Mouse	Lymph	MS-1	2.4e-12
Aqp8	GOBP_Response_To_Camp	Mouse	Lymph	MS-1	4.1e-16
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lymph	MS-1	3.9e-13
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Lymph	MS-1	1.8e-09
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lymph	MS-1	1.9e-09
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lymph	MS-1	1.8e-09
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Lymph	MS-1	1.3e-12
Aqp8	GOBP_Water_Transport	Mouse	Lymph	MS-1	3.8e-13
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Lung	rep_1	2.0e-30
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Lung	rep_1	5.0e-17
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Lung	rep_1	1.2e-19
Aqp8	GOBP_Cellular_Response_To_Camp	Mouse	Brain	HP_ad_rep7	9.8e-10
Aqp8	GOBP_Cellular_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	2.8e-12
Aqp8	GOBP_Cellular_Response_To_Organic_Cyclic_Compound	Mouse	Brain	HP_ad_rep7	2.6e-09
Aqp8	GOBP_Cellular_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	2.6e-10
Aqp8	GOBP_Response_To_Endogenous_Stimulus	Mouse	Brain	HP_ad_rep7	6.3e-10
Aqp8	GOBP_Response_To_Nitrogen_Compound	Mouse	Brain	HP_ad_rep7	3.5e-10
Aqp8	GOBP_Response_To_Organic_Cyclic_Compound	Mouse	Brain	HP_ad_rep7	1.4e-09
Aqp8	GOBP_Response_To_Oxygen_Containing_Compound	Mouse	Brain	HP_ad_rep7	4.2e-09
Aqp8	GOBP_Transmembrane_Transport	Mouse	Brain	HP_ad_rep7	3.4e-07
Aqp8	GOBP_Response_To_Camp	Mouse	Brain	HP_adpolb_rep1	2.7e-12
Aqp8	GOBP_Response_To_Purine_Containing_Compound	Mouse	Brain	HP_adpolb_rep1	9.0e-07
Aqp8	GOBP_Fluid_Transport	Mouse	Brain	HP_adpolb_rep5	4.1e-10
Aqp8	GOBP_Water_Transport	Mouse	Brain	HP_polb_rep5	6.5e-04

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Aqp8 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Aqp8 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Aqp8 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Aqp8

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Aqp8

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source