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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tgs1 (spascer ID:116940)

Gene summary for Tgs1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tgs1
	Gene ID	116940
	Gene name	trimethylguanosine synthase 1
	Synonyms	D4Ertd800e\|Ncoa6ip\|Pimt
	Cytomap	4 A1\|4 1.99 cM
	Type of gene	protein-coding
	Description	trimethylguanosine synthasePIPMTPRIP-interacting protein with methyltransferase motifnuclear receptor coactivator 6-interacting proteintrimethylguanosine synthase homolog
	Modification date	20220507
	UniProtAcc	Q923W1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tgs1	GO:0005634	nucleus	21873635	Component
Tgs1	GO:0036261	7-methylguanosine cap hypermethylation	21873635	Process
Tgs1	GO:0071164	RNA trimethylguanosine synthase activity	21873635	Function

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Spatial pattern events for Tgs1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tgs1	Mouse	Kidney	rep_1	34853151	4.41e-06
Tgs1	Mouse	Testicle	rep_5	34731600	7.39e-07
Tgs1	Mouse	Lymph	A1	0	6.00e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_1_H&E

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Spatial pattern pathway has Tgs1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tgs1	GOBP_Rna_Capping	Mouse	Spinal cord	CN80_E1	9.2e-06
Tgs1	GOBP_Methylation	Mouse	Spinal cord	CN94_E1	7.7e-06
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Tgs1	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Tgs1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Tgs1	GOBP_Rna_Methylation	Mouse	Spinal cord	L7CN45_C1	8.4e-07
Tgs1	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Tgs1	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Tgs1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Tgs1	GOBP_Spliceosomal_Snrnp_Assembly	Mouse	Spinal cord	L7CN45_C1	7.4e-06
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Spinal cord	L8CN11_D2	2.5e-11
Tgs1	GOBP_Rna_Modification	Mouse	Spinal cord	L8CN17_E1	4.8e-08
Tgs1	GOBP_Rna_Methylation	Mouse	Brain	rep_27	1.7e-10
Tgs1	GOBP_Rna_Capping	Mouse	Brain	rep_36	2.6e-07
Tgs1	GOBP_Rna_Capping	Mouse	Brain	rep_1	2.4e-19
Tgs1	GOBP_Methylation	Mouse	Brain	rep_3	3.9e-199
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Tgs1	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Brain	rep_3	2.9e-55
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	rep_3	5.6e-32
Tgs1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	rep_3	6.1e-80
Tgs1	GOBP_Rna_Methylation	Mouse	Brain	rep_3	9.0e-81
Tgs1	GOBP_Rna_Modification	Mouse	Brain	rep_3	1.8e-211
Tgs1	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Tgs1	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Tgs1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Tgs1	GOBP_Spliceosomal_Snrnp_Assembly	Mouse	Brain	rep_3	5.8e-214
Tgs1	GOBP_Rna_Capping	Mouse	Embryo	rep_6	1.9e-14
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Embryo	rep_14	2.1e-33
Tgs1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Embryo	rep_14	6.2e-25
Tgs1	GOBP_Rna_Methylation	Mouse	Embryo	rep_14	2.0e-39
Tgs1	GOBP_Rna_Modification	Mouse	Embryo	rep_14	3.1e-46
Tgs1	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Tgs1	GOBP_Spliceosomal_Snrnp_Assembly	Mouse	Embryo	rep_14	5.8e-36
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Tgs1	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Tgs1	GOBP_Methylation	Mouse	Embryo	rep_3	0.0e+00
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Embryo	rep_3	5.4e-203
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Tgs1	GOBP_Methylation	Mouse	Kidney	rep_2	2.7e-54
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Tgs1	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	3.6e-73
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Kidney	rep_2	1.3e-69
Tgs1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Kidney	rep_2	3.3e-25
Tgs1	GOBP_Rna_Capping	Mouse	Kidney	rep_2	7.6e-36
Tgs1	GOBP_Rna_Methylation	Mouse	Kidney	rep_2	1.2e-52
Tgs1	GOBP_Rna_Modification	Mouse	Kidney	rep_2	7.1e-48
Tgs1	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Tgs1	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Tgs1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Tgs1	GOBP_Spliceosomal_Snrnp_Assembly	Mouse	Kidney	rep_2	1.8e-129
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Tgs1	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Tgs1	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Tgs1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Tgs1	GOBP_Rna_Capping	Mouse	Liver	CN65-C1	1.6e-10
Tgs1	GOBP_Rna_Methylation	Mouse	Liver	CN65-C1	6.8e-09
Tgs1	GOBP_Rna_Methylation	Mouse	Liver	rep_15	5.5e-08
Tgs1	GOBP_Rna_Capping	Mouse	Liver	rep_16	2.0e-09
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Tgs1	GOBP_Methylation	Mouse	Lymph	MS-1	2.5e-08
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	4.6e-15
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Lymph	MS-1	1.7e-07
Tgs1	GOBP_Rna_Capping	Mouse	Lymph	MS-1	4.8e-14
Tgs1	GOBP_Rna_Methylation	Mouse	Lymph	MS-1	7.5e-10
Tgs1	GOBP_Rna_Modification	Mouse	Lymph	MS-1	9.8e-15
Tgs1	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Tgs1	GOBP_Methylation	Mouse	Brain	rep_7	1.2e-08
Tgs1	GOBP_Rna_Methylation	Mouse	Brain	rep_7	3.1e-08
Tgs1	GOBP_Rna_Modification	Mouse	Brain	rep_7	3.9e-16
Tgs1	GOBP_Methylation	Mouse	Brain	HP_ad_rep7	1.4e-10
Tgs1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Tgs1	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Tgs1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	HP_ad_rep7	7.9e-07
Tgs1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	8.3e-08
Tgs1	GOBP_Rna_Capping	Mouse	Brain	HP_ad_rep7	1.4e-24
Tgs1	GOBP_Rna_Methylation	Mouse	Brain	HP_ad_rep7	4.1e-11
Tgs1	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Tgs1	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Tgs1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11
Tgs1	GOBP_Rna_Modification	Mouse	Brain	HP_adpolb_rep1	5.1e-09
Tgs1	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Tgs1	GOBP_Regulation_Of_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.8e-10
Tgs1	GOBP_Spliceosomal_Snrnp_Assembly	Mouse	Brain	HP_polb_rep9	1.2e-12

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Tgs1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Tgs1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Tgs1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Tgs1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Tgs1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source