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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Etfa (spascer ID:110842)

Gene summary for Etfa

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Etfa
	Gene ID	110842
	Gene name	electron transferring flavoprotein, alpha polypeptide
	Synonyms	2010200I21Rik\|D9Ertd394e
	Cytomap	9\|9 B
	Type of gene	protein-coding
	Description	electron transfer flavoprotein subunit alpha, mitochondrialAlpha-ETF
	Modification date	20220424
	UniProtAcc	Q99LC5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Etfa	GO:0005739	mitochondrion	21873635	Component
Etfa	GO:0009055	electron transfer activity	21873635	Function
Etfa	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	21873635	Process
Etfa	GO:0050660	flavin adenine dinucleotide binding	21873635	Function

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Spatial pattern events for Etfa

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Etfa	Mouse	Brain	S3	34413515	1.64e-15
Etfa	Mouse	Brain	S4	34413515	1.37e-15
Etfa	Mouse	Brain	S6	34413515	1.16e-09
Etfa	Mouse	Brain	24A	32637622	6.99e-08
Etfa	Mouse	Brain	rep_1	35141374	2.02e-15
Etfa	Mouse	Brain	rep_2	35141374	1.69e-15
Etfa	Mouse	Brain	rep_3	35141374	3.81e-11
Etfa	Mouse	Brain	rep_4	35141374	1.57e-15
Etfa	Mouse	Brain	rep_5	35141374	1.47e-15
Etfa	Mouse	Brain	rep_6	35141374	3.15e-15
Etfa	Mouse	Embryo	rep_13	33188776	1.42e-06
Etfa	Mouse	Kidney	CLP	34003797	2.19e-15
Etfa	Mouse	Kidney	IRI	34003797	2.29e-15
Etfa	Mouse	Kidney	Sham	34003797	2.58e-15
Etfa	Mouse	Kidney	rep_1	34853151	2.42e-15
Etfa	Mouse	Kidney	rep_4	34853151	1.10e-09
Etfa	Mouse	Kidney	rep_5	34853151	5.06e-11
Etfa	Mouse	Brain	rep_1	33469025	1.30e-15
Etfa	Mouse	Brain	rep_1	35027729	8.00e-10
Etfa	Mouse	Brain	rep_3	35027729	1.32e-15
Etfa	Mouse	Brain	rep_4	35027729	9.48e-10
Etfa	Mouse	Brain	rep_5	35027729	1.46e-15
Etfa	Mouse	Intestine	rep_1	35149721	1.81e-14
Etfa	Mouse	Intestine	rep_2	35149721	3.44e-15
Etfa	Mouse	Intestine	rep_3	35149721	3.25e-15
Etfa	Mouse	Testicle	rep_3	34731600	2.52e-03
Etfa	Mouse	Lung	rep_1	35290801	6.56e-15
Etfa	Mouse	Lung	rep_2	35290801	8.94e-10
Etfa	Mouse	Lung	rep_3	35290801	5.26e-15
Etfa	Mouse	Lung	rep_4	35290801	3.04e-15
Etfa	Mouse	Brain	rep_4	35210624	1.96e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Lung_rep_3_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Etfa envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-07
Etfa	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	3.7e-06
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Spinal cord	L7bCN02_E1	5.4e-07
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Spinal cord	L7bCN02_E1	5.7e-06
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	8.9e-07
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-07
Etfa	GOBP_Cellular_Respiration	Mouse	Spinal cord	L7CN45_C1	7.0e-07
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Spinal cord	L7CN45_C1	6.8e-07
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.4e-06
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.6e-10
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Spinal cord	L7CN45_C1	2.2e-08
Etfa	GOBP_Lipid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	8.5e-07
Etfa	GOBP_Lipid_Modification	Mouse	Spinal cord	L7CN45_C1	1.8e-06
Etfa	GOBP_Lipid_Oxidation	Mouse	Spinal cord	L7CN45_C1	8.8e-07
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	6.2e-09
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_11	2.7e-06
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Brain	rep_17	5.2e-05
Etfa	GOBP_Cellular_Respiration	Mouse	Brain	rep_71	1.7e-06
Etfa	GOBP_Electron_Transport_Chain	Mouse	Brain	rep_71	2.4e-06
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_71	3.4e-07
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_71	3.6e-06
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_71	2.1e-06
Etfa	GOBP_Lipid_Modification	Mouse	Brain	rep_71	7.0e-06
Etfa	GOBP_Lipid_Oxidation	Mouse	Brain	rep_71	3.6e-06
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_71	8.1e-05
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	rep_71	1.2e-05
Etfa	GOBP_Cellular_Respiration	Mouse	Brain	rep_1	9.5e-36
Etfa	GOBP_Electron_Transport_Chain	Mouse	Brain	rep_1	1.3e-47
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	rep_1	1.1e-29
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	rep_1	5.4e-15
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	rep_1	4.5e-44
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Brain	rep_3	3.5e-106
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	rep_3	1.7e-210
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Brain	rep_3	1.8e-98
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.3e-180
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-41
Etfa	GOBP_Lipid_Catabolic_Process	Mouse	Brain	rep_3	1.4e-121
Etfa	GOBP_Lipid_Modification	Mouse	Brain	rep_3	4.5e-101
Etfa	GOBP_Lipid_Oxidation	Mouse	Brain	rep_3	1.2e-128
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.0e-175
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	3.2e-119
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	rep_3	9.6e-181
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Etfa	GOBP_Cellular_Respiration	Mouse	Embryo	rep_6	3.9e-08
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_14	6.6e-12
Etfa	GOBP_Electron_Transport_Chain	Mouse	Embryo	rep_14	5.7e-46
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Embryo	rep_14	2.3e-31
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Embryo	rep_14	6.7e-36
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Embryo	rep_14	4.0e-17
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Embryo	rep_14	1.8e-09
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Embryo	rep_14	2.9e-37
Etfa	GOBP_Lipid_Modification	Mouse	Embryo	rep_14	3.4e-09
Etfa	GOBP_Lipid_Oxidation	Mouse	Embryo	rep_14	9.5e-24
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	7.1e-14
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_14	7.3e-13
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.3e-13
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Embryo	rep_14	8.9e-41
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Embryo	rep_1	2.1e-39
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Etfa	GOBP_Electron_Transport_Chain	Mouse	Embryo	rep_3	3.7e-124
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.7e-52
Etfa	GOBP_Lipid_Catabolic_Process	Mouse	Embryo	rep_3	2.1e-07
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_4	0.0e+00
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	Nep	4.2e-26
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	2.5e-44
Etfa	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	7.4e-43
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Kidney	rep_2	2.0e-46
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Kidney	rep_2	1.0e-14
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Kidney	rep_2	7.7e-56
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Kidney	rep_2	2.1e-55
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Kidney	rep_2	3.3e-14
Etfa	GOBP_Lipid_Catabolic_Process	Mouse	Kidney	rep_2	1.4e-56
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-78
Etfa	GOBP_Lipid_Modification	Mouse	Kidney	rep_2	1.7e-37
Etfa	GOBP_Lipid_Oxidation	Mouse	Kidney	rep_2	2.1e-13
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.6e-58
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	4.4e-73
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-83
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Liver	CN16-D1	5.7e-11
Etfa	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Liver	CN73-C1	9.9e-09
Etfa	GOBP_Cellular_Respiration	Mouse	Liver	rep_16	8.0e-25
Etfa	GOBP_Electron_Transport_Chain	Mouse	Liver	rep_16	1.7e-16
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Liver	rep_16	2.0e-28
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Liver	rep_16	7.4e-11
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Liver	rep_16	2.4e-29
Etfa	GOBP_Electron_Transport_Chain	Mouse	Intestine	rep_2	8.8e-09
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Intestine	rep_2	2.4e-11
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Intestine	rep_2	5.7e-44
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Intestine	rep_2	3.7e-18
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Intestine	rep_2	3.9e-25
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Intestine	rep_2	1.5e-14
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Intestine	rep_2	2.9e-16
Etfa	GOBP_Cellular_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	3.4e-07
Etfa	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	1.1e-14
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Lymph	MS-1	7.8e-09
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Lymph	MS-1	6.3e-09
Etfa	GOBP_Fatty_Acid_Metabolic_Process	Mouse	Lymph	MS-1	8.4e-16
Etfa	GOBP_Lipid_Catabolic_Process	Mouse	Lymph	MS-1	2.6e-07
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Lymph	MS-1	9.7e-11
Etfa	GOBP_Lipid_Modification	Mouse	Lymph	MS-1	6.5e-09
Etfa	GOBP_Lipid_Oxidation	Mouse	Lymph	MS-1	3.2e-11
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.8e-07
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.1e-10
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Etfa	GOBP_Fatty_Acid_Beta_Oxidation_Using_Acyl_Coa_Dehydrogenase	Mouse	Brain	HP_ad_rep7	1.8e-09
Etfa	GOBP_Fatty_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	4.7e-07
Etfa	GOBP_Monocarboxylic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-10
Etfa	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-13
Etfa	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Etfa	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Etfa	GOBP_Cellular_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.9e-07
Etfa	GOBP_Cellular_Respiration	Mouse	Brain	HP_polb_rep9	2.1e-07
Etfa	GOBP_Electron_Transport_Chain	Mouse	Brain	HP_polb_rep9	5.9e-10
Etfa	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Mouse	Brain	HP_polb_rep9	3.0e-10
Etfa	GOBP_Fatty_Acid_Beta_Oxidation	Mouse	Brain	HP_polb_rep9	2.3e-12
Etfa	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Mouse	Brain	HP_polb_rep9	5.4e-11
Etfa	GOBP_Lipid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.9e-11
Etfa	GOBP_Monocarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.7e-11
Etfa	GOBP_Respiratory_Electron_Transport_Chain	Mouse	Brain	HP_polb_rep9	1.8e-08
Etfa	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Etfa function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Etfa function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Etfa envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Etfa

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Etfa

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Etfa	C0268596	Multiple Acyl Coenzyme A Dehydrogenase Deficiency	11	CLINGEN;CTD_human;GENOMICS_ENGLAND;UNIPROT
Etfa	C0029408	Degenerative polyarthritis	1	CTD_human
Etfa	C0086743	Osteoarthrosis Deformans	1	CTD_human
Etfa	C0369183	Erythrocyte Mean Corpuscular Hemoglobin Test	1	GENOMICS_ENGLAND
Etfa	C1261502	Finding of Mean Corpuscular Hemoglobin	1	GENOMICS_ENGLAND
Etfa	C2239176	Liver carcinoma	1	CTD_human
Etfa	C3278154	GLUTARIC ACIDEMIA IIA	1	GENOMICS_ENGLAND
Etfa	C4317009	Diverticular Diseases	1	CTD_human
Etfa	C4505353	Diverticular Bleeding	1	CTD_human