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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Srsf1 (spascer ID:110809)

Gene summary for Srsf1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Srsf1
	Gene ID	110809
	Gene name	serine and arginine-rich splicing factor 1
	Synonyms	1110054N12Rik\|5730507C05Rik\|6330415C05Rik\|AI482334\|AW491331\|Asf\|Sf2\|Sfrs1
	Cytomap	11 C\|11 52.4 cM
	Type of gene	protein-coding
	Description	serine/arginine-rich splicing factor 1ASF/SF2pre-mRNA-splicing factor SRp30asplicing factor, arginine/serine-rich 1 (ASF/SF2)
	Modification date	20220424
	UniProtAcc	Q6PDM2

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Srsf1	GO:0000380	alternative mRNA splicing, via spliceosome	21873635	Process
Srsf1	GO:0000398	mRNA splicing, via spliceosome	21873635	Process
Srsf1	GO:0003723	RNA binding	21873635	Function
Srsf1	GO:0016607	nuclear speck	21873635	Component

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Spatial pattern events for Srsf1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Srsf1	Mouse	Brain	S2	34413515	2.31e-13
Srsf1	Mouse	Brain	S4	34413515	2.43e-15
Srsf1	Mouse	Brain	S6	34413515	1.88e-06
Srsf1	Mouse	Brain	S7	34413515	2.15e-14
Srsf1	Mouse	Brain	rep_3	35141374	9.32e-10
Srsf1	Mouse	Brain	rep_5	35141374	2.05e-07
Srsf1	Mouse	Embryo	rep_3	33188776	9.65e-08
Srsf1	Mouse	Kidney	rep_1	34853151	4.55e-06
Srsf1	Mouse	Kidney	rep_5	34853151	2.89e-08
Srsf1	Mouse	Brain	rep_1	33469025	1.30e-15
Srsf1	Mouse	Brain	rep_1	35027729	1.07e-09
Srsf1	Mouse	Brain	rep_2	35027729	3.80e-06
Srsf1	Mouse	Brain	rep_3	35027729	8.76e-07
Srsf1	Mouse	Brain	rep_4	35027729	3.47e-06
Srsf1	Mouse	Brain	rep_5	35027729	4.92e-07
Srsf1	Mouse	Intestine	rep_3	35149721	5.37e-10
Srsf1	Mouse	Intestine	rep_4	35149721	2.30e-15
Srsf1	Mouse	Lymph	A1	0	3.29e-15
Srsf1	Mouse	Lymph	B1	0	3.66e-15
Srsf1	Mouse	Brain	rep_1	35210624	1.74e-15
Srsf1	Mouse	Brain	rep_2	35210624	1.74e-15
Srsf1	Mouse	Brain	rep_3	35210624	4.87e-14
Srsf1	Mouse	Brain	OFB_adpolb_rep3	33083725	6.73e-04

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_3_H&E
Brain_rep_5_H&E
Kidney_rep_1_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_OFB_adpolb_rep3_H&E

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Spatial pattern pathway has Srsf1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.9e-06
Srsf1	GOBP_Mrna_Transport	Mouse	Spinal cord	CN94_E1	4.5e-06
Srsf1	GOBP_Rna_Localization	Mouse	Spinal cord	CN94_E1	3.7e-06
Srsf1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Spinal cord	L7bCN01_D2	2.0e-06
Srsf1	GOBP_Mrna_Processing	Mouse	Spinal cord	L7bCN02_E1	5.5e-06
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Spinal cord	L7bCN02_E1	6.8e-06
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Spinal cord	L7bCN02_E1	8.2e-06
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Spinal cord	L7CN45_C1	4.2e-07
Srsf1	GOBP_Establishment_Of_Protein_Localization	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Spinal cord	L7CN45_C1	4.1e-06
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Spinal cord	L7CN45_C1	3.6e-07
Srsf1	GOBP_Intracellular_Transport	Mouse	Spinal cord	L7CN45_C1	4.4e-06
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Spinal cord	L7CN45_C1	9.8e-06
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Spinal cord	L7CN45_C1	9.9e-08
Srsf1	GOBP_Mrna_Export_From_Nucleus	Mouse	Spinal cord	L7CN45_C1	3.8e-06
Srsf1	GOBP_Mrna_Splice_Site_Selection	Mouse	Spinal cord	L7CN45_C1	9.3e-07
Srsf1	GOBP_Nuclear_Export	Mouse	Spinal cord	L7CN45_C1	8.7e-09
Srsf1	GOBP_Nuclear_Transport	Mouse	Spinal cord	L7CN45_C1	6.5e-07
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Srsf1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Srsf1	GOBP_Rna_Export_From_Nucleus	Mouse	Spinal cord	L7CN45_C1	1.9e-07
Srsf1	GOBP_Rna_Processing	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Srsf1	GOBP_Rna_Splicing	Mouse	Spinal cord	L7CN45_C1	3.7e-08
Srsf1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Spinal cord	L7CN45_C1	1.8e-09
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Spinal cord	L7CN45_C1	2.1e-07
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Spinal cord	L7CN60_D1	6.4e-07
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_27	3.0e-05
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_27	4.5e-09
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Brain	rep_37	8.0e-05
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Brain	rep_41	9.2e-06
Srsf1	GOBP_Mrna_Transport	Mouse	Brain	rep_41	2.9e-05
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Brain	rep_41	8.4e-06
Srsf1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	rep_1	1.8e-13
Srsf1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	rep_1	6.6e-07
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Brain	rep_1	8.1e-07
Srsf1	GOBP_Mrna_Splice_Site_Selection	Mouse	Brain	rep_1	1.1e-22
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Brain	rep_1	5.8e-25
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Brain	rep_1	2.2e-11
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	rep_3	1.6e-125
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Brain	rep_3	4.2e-183
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Brain	rep_3	2.7e-132
Srsf1	GOBP_Intracellular_Transport	Mouse	Brain	rep_3	1.0e-102
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Brain	rep_3	7.2e-255
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Brain	rep_3	5.0e-185
Srsf1	GOBP_Mrna_Export_From_Nucleus	Mouse	Brain	rep_3	1.9e-204
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	rep_3	3.9e-221
Srsf1	GOBP_Mrna_Processing	Mouse	Brain	rep_3	4.7e-219
Srsf1	GOBP_Mrna_Transport	Mouse	Brain	rep_3	2.1e-196
Srsf1	GOBP_Nuclear_Export	Mouse	Brain	rep_3	2.2e-177
Srsf1	GOBP_Nuclear_Transport	Mouse	Brain	rep_3	1.4e-181
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Brain	rep_3	4.8e-165
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	rep_3	5.6e-32
Srsf1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	rep_3	6.1e-80
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Brain	rep_3	2.2e-166
Srsf1	GOBP_Rna_Export_From_Nucleus	Mouse	Brain	rep_3	6.2e-186
Srsf1	GOBP_Rna_Localization	Mouse	Brain	rep_3	6.0e-194
Srsf1	GOBP_Rna_Processing	Mouse	Brain	rep_3	4.3e-140
Srsf1	GOBP_Rna_Splicing	Mouse	Brain	rep_3	2.2e-224
Srsf1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	rep_3	1.8e-234
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Embryo	rep_14	1.4e-19
Srsf1	GOBP_Nuclear_Export	Mouse	Embryo	rep_14	1.8e-13
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Embryo	rep_14	9.1e-09
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Embryo	rep_14	2.1e-33
Srsf1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Embryo	rep_14	6.2e-25
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_14	4.1e-27
Srsf1	GOBP_Rna_Export_From_Nucleus	Mouse	Embryo	rep_14	3.2e-16
Srsf1	GOBP_Rna_Localization	Mouse	Embryo	rep_14	4.6e-13
Srsf1	GOBP_Rna_Processing	Mouse	Embryo	rep_14	3.5e-14
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Embryo	rep_1	5.8e-21
Srsf1	GOBP_Nuclear_Transport	Mouse	Embryo	rep_1	5.4e-112
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Embryo	rep_2	5.5e-15
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Embryo	rep_2	4.2e-15
Srsf1	GOBP_Mrna_Transport	Mouse	Embryo	rep_2	4.2e-15
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Embryo	rep_2	4.9e-137
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Embryo	rep_2	2.8e-16
Srsf1	GOBP_Rna_Localization	Mouse	Embryo	rep_2	4.2e-15
Srsf1	GOBP_Rna_Processing	Mouse	Embryo	rep_2	2.4e-14
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Embryo	rep_4	1.1e-39
Srsf1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Kidney	rep_2	1.8e-64
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Kidney	rep_2	3.5e-61
Srsf1	GOBP_Establishment_Of_Protein_Localization	Mouse	Kidney	rep_2	9.8e-86
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Kidney	rep_2	7.4e-72
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Kidney	rep_2	7.5e-54
Srsf1	GOBP_Intracellular_Transport	Mouse	Kidney	rep_2	7.9e-80
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Kidney	rep_2	2.0e-28
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Kidney	rep_2	6.0e-37
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Kidney	rep_2	1.0e-64
Srsf1	GOBP_Mrna_Export_From_Nucleus	Mouse	Kidney	rep_2	2.0e-42
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Kidney	rep_2	3.1e-08
Srsf1	GOBP_Mrna_Processing	Mouse	Kidney	rep_2	5.0e-53
Srsf1	GOBP_Mrna_Splice_Site_Selection	Mouse	Kidney	rep_2	4.0e-79
Srsf1	GOBP_Mrna_Transport	Mouse	Kidney	rep_2	2.4e-42
Srsf1	GOBP_Nuclear_Export	Mouse	Kidney	rep_2	1.0e-81
Srsf1	GOBP_Nuclear_Transport	Mouse	Kidney	rep_2	4.2e-27
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Kidney	rep_2	3.6e-85
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Kidney	rep_2	6.5e-74
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Kidney	rep_2	1.3e-69
Srsf1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Kidney	rep_2	3.3e-25
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Kidney	rep_2	2.8e-70
Srsf1	GOBP_Rna_Export_From_Nucleus	Mouse	Kidney	rep_2	3.8e-73
Srsf1	GOBP_Rna_Localization	Mouse	Kidney	rep_2	1.1e-66
Srsf1	GOBP_Rna_Processing	Mouse	Kidney	rep_2	1.1e-71
Srsf1	GOBP_Rna_Splicing	Mouse	Kidney	rep_2	1.1e-33
Srsf1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Kidney	rep_2	8.8e-36
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Kidney	rep_2	1.5e-73
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Liver	CN16-D2	5.2e-07
Srsf1	GOBP_Mrna_Processing	Mouse	Liver	CN16-D2	4.8e-09
Srsf1	GOBP_Rna_Splicing	Mouse	Liver	CN16-D2	2.4e-07
Srsf1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Liver	CN16-D2	2.0e-09
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Liver	CN65-C1	5.7e-07
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Liver	rep_15	5.2e-13
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Liver	rep_16	1.7e-09
Srsf1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Lymph	MS-1	2.8e-07
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Lymph	MS-1	1.1e-11
Srsf1	GOBP_Establishment_Of_Protein_Localization	Mouse	Lymph	MS-1	2.5e-11
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Lymph	MS-1	3.0e-17
Srsf1	GOBP_Intracellular_Transport	Mouse	Lymph	MS-1	3.3e-11
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Lymph	MS-1	2.6e-07
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Lymph	MS-1	3.1e-09
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Lymph	MS-1	8.2e-07
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Lymph	MS-1	3.2e-11
Srsf1	GOBP_Nuclear_Transport	Mouse	Lymph	MS-1	1.5e-07
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Lymph	MS-1	5.8e-08
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Lymph	MS-1	7.4e-09
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Lymph	MS-1	1.7e-07
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Lymph	MS-1	1.5e-11
Srsf1	GOBP_Rna_Processing	Mouse	Lymph	MS-1	2.0e-09
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Lymph	MS-1	4.7e-07
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Lymph	MS-2	2.7e-07
Srsf1	GOBP_Mrna_Splice_Site_Selection	Mouse	Brain	rep_4	4.2e-12
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Brain	rep_4	2.2e-09
Srsf1	GOBP_Mrna_5_Splice_Site_Recognition	Mouse	Brain	HP_ad_rep3	4.0e-07
Srsf1	GOBP_Alternative_Mrna_Splicing_Via_Spliceosome	Mouse	Brain	HP_ad_rep7	6.7e-08
Srsf1	GOBP_Cellular_Macromolecule_Localization	Mouse	Brain	HP_ad_rep7	6.6e-10
Srsf1	GOBP_Establishment_Of_Protein_Localization	Mouse	Brain	HP_ad_rep7	8.7e-10
Srsf1	GOBP_Establishment_Of_Rna_Localization	Mouse	Brain	HP_ad_rep7	1.8e-14
Srsf1	GOBP_Intracellular_Protein_Transport	Mouse	Brain	HP_ad_rep7	3.6e-08
Srsf1	GOBP_Intracellular_Transport	Mouse	Brain	HP_ad_rep7	3.1e-08
Srsf1	GOBP_Mrna_3_End_Processing	Mouse	Brain	HP_ad_rep7	3.7e-18
Srsf1	GOBP_Mrna_Cis_Splicing_Via_Spliceosome	Mouse	Brain	HP_ad_rep7	5.9e-07
Srsf1	GOBP_Mrna_Export_From_Nucleus	Mouse	Brain	HP_ad_rep7	7.6e-08
Srsf1	GOBP_Mrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-09
Srsf1	GOBP_Mrna_Processing	Mouse	Brain	HP_ad_rep7	2.3e-09
Srsf1	GOBP_Mrna_Splice_Site_Selection	Mouse	Brain	HP_ad_rep7	3.6e-09
Srsf1	GOBP_Mrna_Transport	Mouse	Brain	HP_ad_rep7	9.0e-13
Srsf1	GOBP_Nuclear_Export	Mouse	Brain	HP_ad_rep7	3.6e-08
Srsf1	GOBP_Nucleobase_Containing_Compound_Transport	Mouse	Brain	HP_ad_rep7	1.5e-09
Srsf1	GOBP_Protein_Containing_Complex_Localization	Mouse	Brain	HP_ad_rep7	2.7e-07
Srsf1	GOBP_Ribonucleoprotein_Complex_Biogenesis	Mouse	Brain	HP_ad_rep7	7.9e-07
Srsf1	GOBP_Ribonucleoprotein_Complex_Subunit_Organization	Mouse	Brain	HP_ad_rep7	8.3e-08
Srsf1	GOBP_Rna_3_End_Processing	Mouse	Brain	HP_ad_rep7	1.1e-14
Srsf1	GOBP_Rna_Export_From_Nucleus	Mouse	Brain	HP_ad_rep7	1.2e-09
Srsf1	GOBP_Rna_Localization	Mouse	Brain	HP_ad_rep7	8.4e-16
Srsf1	GOBP_Rna_Processing	Mouse	Brain	HP_ad_rep7	2.7e-09
Srsf1	GOBP_Rna_Splicing	Mouse	Brain	HP_ad_rep7	5.3e-10
Srsf1	GOBP_Rna_Splicing_Via_Transesterification_Reactions	Mouse	Brain	HP_ad_rep7	2.3e-11
Srsf1	GOBP_Spliceosomal_Complex_Assembly	Mouse	Brain	HP_ad_rep7	1.6e-13
Srsf1	GOBP_Nuclear_Transport	Mouse	Brain	HP_polb_rep9	1.4e-07

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Srsf1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Srsf1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Srsf1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Srsf1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Srsf1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source