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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Tshz1 (spascer ID:110796)

Gene summary for Tshz1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Tshz1
	Gene ID	110796
	Gene name	teashirt zinc finger family member 1
	Synonyms	5730407I04Rik\|D18Bwg1409e\|Mtsh1\|NY-CO-33\|Sdccag33\|Tsh1\|teashirt1
	Cytomap	18 E4\|18 57.53 cM
	Type of gene	protein-coding
	Description	teashirt homolog 1serologically defined colon cancer antigen 3 homologserologically defined colon cancer antigen 33
	Modification date	20220424
	UniProtAcc	Q5DTH5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Tshz1	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	21873635	Function
Tshz1	GO:0003677	DNA binding	21873635	Function
Tshz1	GO:0005634	nucleus	21873635	Component
Tshz1	GO:0006357	regulation of transcription by RNA polymerase II	21873635	Process

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Spatial pattern events for Tshz1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Tshz1	Mouse	Brain	S1	34413515	3.73e-15
Tshz1	Mouse	Brain	S2	34413515	9.54e-10
Tshz1	Mouse	Brain	S4	34413515	1.21e-10
Tshz1	Mouse	Brain	S6	34413515	2.66e-15
Tshz1	Mouse	Brain	S7	34413515	2.85e-15
Tshz1	Mouse	Brain	01A	32637622	2.75e-06
Tshz1	Mouse	Brain	01B	32637622	2.69e-13
Tshz1	Mouse	Brain	04A	32637622	2.00e-12
Tshz1	Mouse	Brain	04B	32637622	7.38e-13
Tshz1	Mouse	Brain	05A	32637622	3.09e-14
Tshz1	Mouse	Brain	05B	32637622	2.37e-13
Tshz1	Mouse	Brain	06A	32637622	1.21e-09
Tshz1	Mouse	Brain	06B	32637622	1.36e-09
Tshz1	Mouse	Brain	22A	32637622	5.54e-09
Tshz1	Mouse	Brain	rep_1	35141374	2.51e-13
Tshz1	Mouse	Brain	rep_3	35141374	7.87e-13
Tshz1	Mouse	Brain	rep_4	35141374	5.42e-15
Tshz1	Mouse	Brain	rep_5	35141374	7.57e-06
Tshz1	Mouse	Brain	rep_6	35141374	6.47e-10
Tshz1	Mouse	Embryo	rep_2	33188776	1.37e-14
Tshz1	Mouse	Embryo	rep_3	33188776	1.13e-14
Tshz1	Mouse	Embryo	rep_4	33188776	8.29e-15
Tshz1	Mouse	Embryo	rep_5	33188776	1.40e-14
Tshz1	Mouse	Embryo	rep_12	33188776	8.45e-09
Tshz1	Mouse	Embryo	rep_13	33188776	4.49e-15
Tshz1	Mouse	Kidney	IRI	34003797	3.92e-15
Tshz1	Mouse	Kidney	rep_5	34853151	3.21e-10
Tshz1	Mouse	Brain	rep_1	33469025	1.30e-15
Tshz1	Mouse	Brain	rep_1	35027729	5.64e-15
Tshz1	Mouse	Brain	rep_2	35027729	1.57e-15
Tshz1	Mouse	Brain	rep_3	35027729	2.38e-15
Tshz1	Mouse	Brain	rep_4	35027729	1.76e-14
Tshz1	Mouse	Brain	rep_5	35027729	1.46e-15
Tshz1	Mouse	Testicle	rep_4	34731600	1.30e-15
Tshz1	Mouse	Lymph	A1	0	2.07e-08
Tshz1	Mouse	Lymph	B1	0	6.08e-15
Tshz1	Mouse	Lung	rep_1	35290801	7.08e-09
Tshz1	Mouse	Lung	rep_2	35290801	1.04e-07
Tshz1	Mouse	Brain	rep_5	35210624	3.62e-15
Tshz1	Mouse	Brain	rep_6	35210624	3.65e-15
Tshz1	Mouse	Brain	rep_7	35210624	1.86e-14
Tshz1	Mouse	Brain	OFB_ad_rep1	33083725	1.59e-04
Tshz1	Mouse	Brain	OFB_ad_rep2	33083725	6.71e-06
Tshz1	Mouse	Brain	OFB_ad_rep3	33083725	6.25e-08
Tshz1	Mouse	Brain	OFB_ad_rep4	33083725	6.01e-13
Tshz1	Mouse	Brain	OFB_adpolb_rep1	33083725	5.64e-05
Tshz1	Mouse	Brain	OFB_adpolb_rep2	33083725	1.73e-09
Tshz1	Mouse	Brain	OFB_adpolb_rep3	33083725	7.11e-13
Tshz1	Mouse	Brain	OFB_adpolb_rep4	33083725	4.74e-13
Tshz1	Mouse	Brain	OFB_adpolb_rep6	33083725	7.25e-03
Tshz1	Mouse	Brain	OFB_polb_rep5	33083725	1.91e-03
Tshz1	Mouse	Brain	OFB_polb_rep6	33083725	2.50e-07
Tshz1	Mouse	Brain	OFB_wt_rep3	33083725	1.37e-10
Tshz1	Mouse	Brain	OFB_wt_rep4	33083725	2.41e-06
Tshz1	Mouse	Brain	OFB_wt_rep5	33083725	1.87e-04

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_IRI_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E
Brain_OFB_ad_rep1_H&E
Brain_OFB_ad_rep2_H&E
Brain_OFB_ad_rep3_H&E
Brain_OFB_ad_rep4_H&E
Brain_OFB_adpolb_rep1_H&E
Brain_OFB_adpolb_rep2_H&E
Brain_OFB_adpolb_rep3_H&E
Brain_OFB_adpolb_rep4_H&E
Brain_OFB_adpolb_rep6_H&E
Brain_OFB_polb_rep5_H&E
Brain_OFB_polb_rep6_H&E
Brain_OFB_wt_rep3_H&E
Brain_OFB_wt_rep4_H&E
Brain_OFB_wt_rep5_H&E

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Spatial pattern pathway has Tshz1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	6.6e-06
Tshz1	GOBP_Ear_Development	Mouse	Spinal cord	CN94_E1	1.3e-06
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Spinal cord	CN94_E1	7.7e-07
Tshz1	GOBP_Regionalization	Mouse	Spinal cord	CN94_E1	7.3e-06
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Spinal cord	CN94_E1	4.5e-06
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Spinal cord	L7bCN05_D1	4.9e-06
Tshz1	GOBP_Soft_Palate_Development	Mouse	Spinal cord	L7CN44_C1	8.6e-06
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	2.5e-06
Tshz1	GOBP_Embryo_Development	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Tshz1	GOBP_Embryonic_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Spinal cord	L7CN45_C1	5.4e-06
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Spinal cord	L8CN17_E1	2.7e-06
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_27	2.0e-06
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	rep_27	3.1e-05
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_27	3.2e-09
Tshz1	GOBP_Regionalization	Mouse	Brain	rep_27	3.9e-08
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_27	4.9e-05
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Brain	rep_41	2.8e-16
Tshz1	GOBP_Soft_Palate_Development	Mouse	Brain	rep_70	2.0e-07
Tshz1	GOBP_Ear_Development	Mouse	Brain	rep_71	2.4e-06
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Brain	rep_71	2.6e-05
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_71	2.6e-07
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Brain	rep_3	5.4e-57
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	rep_3	1.2e-140
Tshz1	GOBP_Ear_Development	Mouse	Brain	rep_3	8.9e-191
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Brain	rep_3	6.0e-188
Tshz1	GOBP_Embryo_Development	Mouse	Brain	rep_3	1.3e-126
Tshz1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	rep_3	5.0e-165
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_3	4.3e-190
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-168
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Brain	rep_3	1.6e-79
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_3	1.6e-118
Tshz1	GOBP_Regionalization	Mouse	Brain	rep_3	1.3e-180
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Brain	rep_3	1.3e-148
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Brain	rep_3	6.3e-65
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Brain	rep_3	1.6e-123
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	rep_3	1.5e-133
Tshz1	GOBP_Soft_Palate_Development	Mouse	Brain	rep_3	2.0e-38
Tshz1	GOBP_Ear_Development	Mouse	Embryo	rep_4	8.5e-07
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Embryo	rep_4	2.7e-14
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Embryo	rep_6	1.5e-09
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Embryo	rep_6	1.2e-25
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Embryo	rep_6	9.7e-17
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Embryo	rep_14	2.2e-13
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_14	7.1e-17
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Embryo	rep_1	1.7e-10
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Embryo	rep_2	8.6e-166
Tshz1	GOBP_Regionalization	Mouse	Embryo	rep_2	5.4e-84
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Embryo	rep_3	2.8e-70
Tshz1	GOBP_Embryo_Development	Mouse	Embryo	rep_3	1.2e-173
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Embryo	rep_3	2.8e-168
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Embryo	rep_3	0.0e+00
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Embryo	rep_3	2.1e-266
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Embryo	rep_3	9.1e-62
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Kidney	rep_2	4.2e-71
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Kidney	rep_2	3.0e-23
Tshz1	GOBP_Ear_Development	Mouse	Kidney	rep_2	4.5e-86
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Kidney	rep_2	7.6e-61
Tshz1	GOBP_Embryo_Development	Mouse	Kidney	rep_2	7.4e-46
Tshz1	GOBP_Embryonic_Morphogenesis	Mouse	Kidney	rep_2	7.3e-66
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Kidney	rep_2	1.3e-60
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.0e-55
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Kidney	rep_2	5.4e-81
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Kidney	rep_2	2.3e-36
Tshz1	GOBP_Regionalization	Mouse	Kidney	rep_2	2.1e-25
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Kidney	rep_2	5.0e-42
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Kidney	rep_2	4.7e-27
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Kidney	rep_2	3.2e-88
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Liver	CN16-D2	1.7e-07
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Liver	CN65-C1	8.1e-07
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Liver	CN73-C1	2.4e-07
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Liver	CN73-C1	7.2e-07
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Liver	rep_15	1.1e-07
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Liver	rep_15	1.4e-19
Tshz1	GOBP_Soft_Palate_Development	Mouse	Liver	rep_15	4.9e-20
Tshz1	GOBP_Ear_Development	Mouse	Liver	rep_16	3.8e-11
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Liver	rep_16	2.7e-07
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Liver	rep_16	3.6e-20
Tshz1	GOBP_Regionalization	Mouse	Liver	rep_16	1.2e-11
Tshz1	GOBP_Animal_Organ_Morphogenesis	Mouse	Lymph	MS-1	4.4e-09
Tshz1	GOBP_Ear_Development	Mouse	Lymph	MS-1	1.7e-07
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Lymph	MS-1	3.2e-11
Tshz1	GOBP_Embryo_Development	Mouse	Lymph	MS-1	2.5e-08
Tshz1	GOBP_Embryonic_Morphogenesis	Mouse	Lymph	MS-1	5.6e-07
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Lymph	MS-1	1.1e-11
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Lymph	MS-1	1.4e-11
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Lymph	MS-1	1.7e-10
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Lymph	MS-1	3.9e-12
Tshz1	GOBP_Regionalization	Mouse	Lymph	MS-1	2.7e-12
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Lymph	MS-1	6.4e-09
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Lymph	MS-1	1.5e-10
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Lymph	MS-1	3.6e-12
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Lung	rep_1	2.2e-11
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Lung	rep_1	7.9e-07
Tshz1	GOBP_Regionalization	Mouse	Brain	rep_4	6.3e-07
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Brain	rep_7	7.0e-07
Tshz1	GOBP_Embryonic_Organ_Morphogenesis	Mouse	Brain	rep_7	2.6e-14
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Brain	rep_7	1.0e-12
Tshz1	GOBP_Middle_Ear_Morphogenesis	Mouse	Brain	HP_ad_rep3	9.0e-11
Tshz1	GOBP_Secondary_Palate_Development	Mouse	Brain	HP_ad_rep3	1.7e-07
Tshz1	GOBP_Soft_Palate_Development	Mouse	Brain	HP_ad_rep3	2.4e-24
Tshz1	GOBP_Ear_Development	Mouse	Brain	HP_ad_rep7	4.1e-07
Tshz1	GOBP_Ear_Morphogenesis	Mouse	Brain	HP_ad_rep7	8.3e-07
Tshz1	GOBP_Pattern_Specification_Process	Mouse	Brain	HP_ad_rep7	2.1e-10
Tshz1	GOBP_Regionalization	Mouse	Brain	HP_ad_rep7	2.8e-09
Tshz1	GOBP_Roof_Of_Mouth_Development	Mouse	Brain	HP_ad_rep7	1.4e-08
Tshz1	GOBP_Sensory_Organ_Development	Mouse	Brain	HP_ad_rep7	4.6e-10
Tshz1	GOBP_Sensory_Organ_Morphogenesis	Mouse	Brain	HP_ad_rep7	9.0e-08
Tshz1	GOBP_Anterior_Posterior_Pattern_Specification	Mouse	Brain	HP_adpolb_rep1	3.0e-08
Tshz1	GOBP_Embryo_Development	Mouse	Brain	HP_polb_rep9	1.5e-10
Tshz1	GOBP_Embryonic_Morphogenesis	Mouse	Brain	HP_polb_rep9	3.7e-09
Tshz1	GOBP_Embryonic_Organ_Development	Mouse	Brain	HP_polb_rep9	9.6e-11

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Tshz1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Tshz1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Tshz1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Tshz1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Tshz1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Tshz1	C0495499	Congenital absence, atresia and stricture of auditory canal (external)	1	ORPHANET
Tshz1	C1842937	AURAL ATRESIA, CONGENITAL	1	CTD_human;GENOMICS_ENGLAND
Tshz1	C2931456	Prostate cancer, familial	1	CTD_human
Tshz1	C4722327	PROSTATE CANCER, HEREDITARY, 1	1	CTD_human