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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Gpt2 (spascer ID:108682)

Gene summary for Gpt2

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Gpt2
	Gene ID	108682
	Gene name	glutamic pyruvate transaminase (alanine aminotransferase) 2
	Synonyms	4631422C05Rik\|ALT2\|AU014768\|AU041193\|C87201
	Cytomap	8\|8 C3
	Type of gene	protein-coding
	Description	alanine aminotransferase 2glutamate pyruvate transaminase 2glutamic--alanine transaminase 2glutamic--pyruvic transaminase 2
	Modification date	20220515
	UniProtAcc	Q8BGT5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene

GO ID

GO term

PubMed ID

Category

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Spatial pattern events for Gpt2

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Gpt2	Mouse	Brain	S4	34413515	5.20e-13
Gpt2	Mouse	Brain	S6	34413515	5.07e-15
Gpt2	Mouse	Brain	S7	34413515	1.55e-15
Gpt2	Mouse	Brain	rep_5	35141374	5.35e-06
Gpt2	Mouse	Kidney	CLP	34003797	2.19e-15
Gpt2	Mouse	Kidney	IRI	34003797	2.29e-15
Gpt2	Mouse	Kidney	Sham	34003797	2.58e-15
Gpt2	Mouse	Kidney	rep_1	34853151	2.03e-08
Gpt2	Mouse	Kidney	rep_3	34853151	1.48e-13
Gpt2	Mouse	Kidney	rep_4	34853151	4.03e-10
Gpt2	Mouse	Kidney	rep_5	34853151	3.18e-15
Gpt2	Mouse	Brain	rep_1	33469025	1.98e-07
Gpt2	Mouse	Liver	rep_20	35021063	1.65e-14
Gpt2	Mouse	Liver	rep_21	35021063	8.03e-15
Gpt2	Mouse	Liver	rep_22	35021063	1.07e-14
Gpt2	Mouse	Brain	rep_1	35027729	3.85e-14
Gpt2	Mouse	Brain	rep_2	35027729	2.56e-06
Gpt2	Mouse	Brain	rep_3	35027729	2.38e-15
Gpt2	Mouse	Intestine	rep_4	35149721	2.40e-07
Gpt2	Mouse	Lymph	A1	0	3.29e-15
Gpt2	Mouse	Lymph	B1	0	3.66e-15
Gpt2	Mouse	Lung	rep_1	35290801	7.85e-12
Gpt2	Mouse	Brain	rep_1	35210624	2.71e-06
Gpt2	Mouse	Brain	rep_2	35210624	1.83e-06
Gpt2	Mouse	Brain	OFB_adpolb_rep3	33083725	6.58e-04
Gpt2	Mouse	Brain	OFB_adpolb_rep4	33083725	1.19e-03
Gpt2	Mouse	Brain	OFB_wt_rep5	33083725	6.08e-05

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Kidney_rep_4_H&E
Kidney_rep_5_H&E
Brain_rep_1_H&E
Liver_rep_20_H&E
Liver_rep_21_H&E
Liver_rep_22_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Lung_rep_1_H&E
Brain_OFB_adpolb_rep3_H&E
Brain_OFB_adpolb_rep4_H&E
Brain_OFB_wt_rep5_H&E

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Spatial pattern pathway has Gpt2 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Spinal cord	CN94_E1	3.5e-07
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.5e-07
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Spinal cord	L7CN34_C1	4.9e-07
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.8e-07
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.1e-08
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN60_D1	5.3e-06
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Spinal cord	L7CN60_D1	5.0e-06
Gpt2	GOBP_2_Oxoglutarate_Metabolic_Process	Mouse	Spinal cord	L7CN97_E2	6.2e-07
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_11	1.9e-05
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_71	7.6e-05
Gpt2	GOBP_2_Oxoglutarate_Metabolic_Process	Mouse	Brain	rep_3	1.4e-100
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Brain	rep_3	1.2e-30
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_3	2.6e-126
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	2.8e-178
Gpt2	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	6.3e-192
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Brain	rep_3	1.6e-133
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	8.5e-191
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.2e-146
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	rep_3	2.0e-17
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	rep_3	9.6e-181
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	rep_3	7.1e-166
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	rep_3	9.8e-142
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Gpt2	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Mouse	Embryo	rep_6	4.1e-27
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Embryo	rep_6	7.1e-08
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Embryo	rep_13	4.9e-08
Gpt2	GOBP_2_Oxoglutarate_Metabolic_Process	Mouse	Embryo	rep_14	3.3e-58
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Embryo	rep_14	1.4e-31
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_14	1.5e-20
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.5e-32
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_14	7.1e-24
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Embryo	rep_14	2.3e-13
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_14	7.6e-14
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Embryo	rep_1	5.7e-21
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Embryo	rep_3	2.9e-170
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Embryo	rep_4	1.5e-14
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-199
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Kidney	rep_2	6.9e-48
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	7.2e-36
Gpt2	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	7.5e-80
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Kidney	rep_2	2.4e-48
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-34
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	8.2e-31
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Kidney	rep_2	7.1e-54
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Kidney	rep_2	1.3e-83
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Kidney	rep_2	1.2e-14
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Kidney	rep_2	4.4e-89
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Gpt2	GOBP_2_Oxoglutarate_Metabolic_Process	Mouse	Liver	CN16-D2	2.0e-11
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Liver	CN16-D2	1.6e-08
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Liver	CN16-E1	7.0e-07
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Liver	CN65-D1	3.9e-09
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Intestine	rep_2	1.9e-85
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Lymph	MS-1	7.5e-11
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	2.1e-13
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Lymph	MS-1	8.8e-11
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-13
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Lymph	MS-1	6.1e-15
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Lymph	MS-1	4.1e-10
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Lymph	MS-1	1.2e-13
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Lymph	MS-1	5.1e-07
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_4	1.9e-21
Gpt2	GOBP_Alanine_Catabolic_Process	Mouse	Brain	HP_ad_rep3	2.7e-31
Gpt2	GOBP_Alpha_Amino_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.3e-13
Gpt2	GOBP_Alpha_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.5e-12
Gpt2	GOBP_Cellular_Amino_Acid_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.4e-17
Gpt2	GOBP_Cellular_Amino_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	1.9e-12
Gpt2	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.0e-14
Gpt2	GOBP_Dicarboxylic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	6.2e-09
Gpt2	GOBP_Organic_Acid_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.2e-13
Gpt2	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Gpt2	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Gpt2	GOBP_Organonitrogen_Compound_Catabolic_Process	Mouse	Brain	HP_ad_rep7	3.3e-07
Gpt2	GOBP_Small_Molecule_Catabolic_Process	Mouse	Brain	HP_ad_rep7	2.3e-11
Gpt2	GOBP_2_Oxoglutarate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	1.0e-06
Gpt2	GOBP_Organic_Acid_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	3.8e-07
Gpt2	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Gpt2	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Gpt2 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Gpt2 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Gpt2 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Gpt2

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Gpt2

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Gpt2	C4225388	MENTAL RETARDATION, AUTOSOMAL RECESSIVE 49	2	CTD_human;ORPHANET;UNIPROT
Gpt2	C0025958	Microcephaly	1	GENOMICS_ENGLAND
Gpt2	C1859520	Progressive spasticity	1	GENOMICS_ENGLAND
Gpt2	C3714756	Intellectual Disability	1	GENOMICS_ENGLAND