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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: Mat2b (spascer ID:108645)

Gene summary for Mat2b

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Mat2b

Gene ID

108645

Gene namemethionine adenosyltransferase II, beta
Synonyms1110064C04Rik|2410018D16Rik|AI182287|AU022853|MAT-II|MATIIbeta|TGR
Cytomap11|11 A5
Type of geneprotein-coding
Descriptionmethionine adenosyltransferase 2 subunit betaMAT II betamethionine adenosyltransferase 2 beta subunit
Modification date20220424
UniProtAcc

Q99LB6


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Mat2b

GO:0006556

S-adenosylmethionine biosynthetic process

21873635

Process
Mat2b

GO:0048269

methionine adenosyltransferase complex

21873635

Component
Mat2b

GO:0048270

methionine adenosyltransferase regulator activity

21873635

Function

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Spatial pattern events for Mat2b

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Mat2bMouseBrainS1 344135152.07e-15
Mat2bMouseBrainS2 344135151.56e-15
Mat2bMouseBrainS3 344135151.64e-15
Mat2bMouseBrainS4 344135151.37e-15
Mat2bMouseBrainS6 344135151.46e-15
Mat2bMouseBrainS7 344135151.55e-15
Mat2bMouseBrain04B 326376224.97e-08
Mat2bMouseBrain05A 326376227.61e-06
Mat2bMouseBrain06B 326376221.35e-08
Mat2bMouseBrain07A 326376224.87e-08
Mat2bMouseBrain07B 326376225.40e-08
Mat2bMouseBrain09A 326376223.31e-11
Mat2bMouseBrain11A 326376221.61e-14
Mat2bMouseBrain12A 326376223.24e-14
Mat2bMouseBrain12B 326376221.20e-14
Mat2bMouseBrain13A 326376221.06e-09
Mat2bMouseBrain13B 326376222.45e-13
Mat2bMouseBrain14A 326376221.38e-14
Mat2bMouseBrain14B 326376221.35e-14
Mat2bMouseBrain15A 326376221.04e-06
Mat2bMouseBrain15B 326376222.61e-06
Mat2bMouseBrain16A 326376222.48e-10
Mat2bMouseBrain17A 326376221.19e-14
Mat2bMouseBrain17B 326376222.25e-14
Mat2bMouseBrain18A 326376224.16e-11
Mat2bMouseBrain18B 326376223.00e-12
Mat2bMouseBrain19A 326376221.35e-14
Mat2bMouseBrain19B 326376221.42e-12
Mat2bMouseBrain20A 326376222.56e-12
Mat2bMouseBrain20B 326376222.93e-14
Mat2bMouseBrain21A 326376225.31e-13
Mat2bMouseBrain21B 326376221.37e-14
Mat2bMouseBrain22A 326376228.87e-15
Mat2bMouseBrain22B 326376228.81e-15
Mat2bMouseBrain23A 326376223.37e-08
Mat2bMouseBrain23B 326376222.86e-13
Mat2bMouseBrain24B 326376222.20e-14
Mat2bMouseBrain25A 326376227.93e-12
Mat2bMouseBrain26A 326376222.20e-14
Mat2bMouseBrain26B 326376228.57e-11
Mat2bMouseBrain27A 326376221.03e-14
Mat2bMouseBrain27B 326376221.06e-14
Mat2bMouseBrain28A 326376221.06e-14
Mat2bMouseBrain28B 326376222.12e-14
Mat2bMouseBrain29A 326376221.08e-14
Mat2bMouseBrain29B 326376221.08e-14
Mat2bMouseBrain30A 326376221.13e-06
Mat2bMouseBrain32A 326376229.45e-08
Mat2bMouseBrain33A 326376224.92e-10
Mat2bMouseBrain33B 326376221.29e-12
Mat2bMouseBrain34A 326376221.42e-14
Mat2bMouseBrain34B 326376222.61e-10
Mat2bMouseBrain35A 326376221.48e-14
Mat2bMouseBrain35B 326376221.78e-14
Mat2bMouseBrainrep_1 351413742.02e-15
Mat2bMouseBrainrep_2 351413741.69e-15
Mat2bMouseBrainrep_3 351413741.64e-15
Mat2bMouseBrainrep_4 351413741.57e-15
Mat2bMouseBrainrep_5 351413741.47e-15
Mat2bMouseBrainrep_6 351413741.73e-15
Mat2bMouseKidneyrep_1 348531512.89e-13
Mat2bMouseBrainrep_1 334690251.30e-15
Mat2bMouseBrainrep_1 350277291.66e-15
Mat2bMouseBrainrep_2 350277291.57e-15
Mat2bMouseBrainrep_3 350277291.32e-15
Mat2bMouseBrainrep_4 350277291.76e-15
Mat2bMouseBrainrep_5 350277291.46e-15
Mat2bMouseBrainB02_D1 327023142.46e-09
Mat2bMouseBrainB03_D2 327023144.44e-08
Mat2bMouseBrainN02_D1 327023147.61e-06
Mat2bMouseBrainN03_C2 327023144.22e-08
Mat2bMouseBrainN03_D2 327023144.73e-09
Mat2bMouseBrainN04_D1 327023145.16e-06
Mat2bMouseBrainrep_1 352106241.74e-15
Mat2bMouseBrainrep_2 352106241.74e-15
Mat2bMouseBrainrep_3 352106241.82e-15
Mat2bMouseBrainrep_4 352106247.78e-15
Mat2bMouseBrainrep_5 352106242.07e-15
Mat2bMouseBrainrep_6 352106242.05e-15
Mat2bMouseBrainrep_7 352106241.87e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_rep_6_H&E
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Kidney_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_1_H&E
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Brain_rep_2_H&E
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Brain_rep_3_H&E
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Brain_rep_4_H&E
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Brain_rep_5_H&E
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Brain_B02_D1_H&E
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Brain_B03_D2_H&E
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Brain_N02_D1_H&E
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Brain_N03_C2_H&E
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Brain_N03_D2_H&E
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Brain_N04_D1_H&E
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Spatial pattern pathway has Mat2b envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Mat2bGOBP_MethylationMouseSpinal cordCN94_E1 7.7e-06
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseSpinal cordL7bCN02_E1 1.8e-07
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseSpinal cordL7CN45_C1 1.7e-07
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseSpinal cordL7CN45_C1 4.4e-07
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseBrainrep_71 3.8e-05
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseBrainrep_1 8.2e-08
Mat2bGOBP_MethylationMouseBrainrep_33.9e-199
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseBrainrep_3 2.6e-38
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseBrainrep_3 2.7e-19
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseBrainrep_31.4e-160
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseEmbryorep_14 7.3e-52
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseEmbryorep_14 3.8e-72
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseEmbryorep_14 3.3e-48
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseEmbryorep_14 5.8e-13
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseEmbryorep_1 1.4e-55
Mat2bGOBP_MethylationMouseEmbryorep_3 0.0e+00
Mat2bGOBP_MethylationMouseKidneyrep_2 2.7e-54
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseKidneyrep_28.9e-161
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseKidneyrep_2 8.5e-54
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseKidneyrep_2 1.8e-43
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseKidneyrep_2 8.6e-17
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseLiverCN16-E1 4.4e-30
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseLiverCN65-C1 2.8e-13
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseLiverCN73-C1 3.0e-08
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseIntestinerep_28.4e-138
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseIntestinerep_2 7.1e-07
Mat2bGOBP_MethylationMouseLymphMS-1 2.5e-08
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseLymphMS-1 2.5e-09
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseLymphMS-1 2.6e-11
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseLymphMS-1 4.5e-10
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseLymphMS-1 7.8e-10
Mat2bGOBP_MethylationMouseBrainrep_7 1.2e-08
Mat2bGOBP_MethylationMouseBrainHP_ad_rep7 1.4e-10
Mat2bGOBP_One_Carbon_Metabolic_ProcessMouseBrainHP_ad_rep7 8.4e-10
Mat2bGOBP_S_Adenosylmethionine_Metabolic_ProcessMouseBrainHP_ad_rep7 1.8e-07
Mat2bGOBP_Small_Molecule_Metabolic_ProcessMouseBrainHP_polb_rep9 2.0e-09
Mat2bGOBP_Sulfur_Compound_Biosynthetic_ProcessMouseBrainHP_polb_rep9 2.2e-10
Mat2bGOBP_Sulfur_Compound_Metabolic_ProcessMouseBrainHP_polb_rep9 9.9e-08

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Mat2b function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Mat2b function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Mat2b envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Mat2b

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Mat2b

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource