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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Fam111a (spascer ID:107373)

Gene summary for Fam111a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Fam111a
	Gene ID	107373
	Gene name	family with sequence similarity 111, member A
	Synonyms	4632417K18Rik\|AW413625
	Cytomap	19 A\|19
	Type of gene	protein-coding
	Description	serine protease FAM111Aprotein FAM111A
	Modification date	20220424
	UniProtAcc	Q9D2L9

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Fam111a	GO:0000785	chromatin	21873635	Component
Fam111a	GO:0005634	nucleus	21873635	Component
Fam111a	GO:0006260	DNA replication	21873635	Process

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Spatial pattern events for Fam111a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Fam111a	Mouse	Embryo	4E	34210887	3.37e-07
Fam111a	Mouse	Embryo	rep_13	33188776	1.32e-09
Fam111a	Mouse	Kidney	rep_5	34853151	1.20e-12
Fam111a	Mouse	Lymph	PBS	0	1.30e-08
Fam111a	Mouse	Lymph	A1	0	5.84e-15
Fam111a	Mouse	Lymph	B1	0	3.66e-15
Fam111a	Mouse	Lung	rep_2	35290801	6.09e-06
Fam111a	Mouse	Lung	rep_4	35290801	2.70e-06

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Kidney_rep_5_H&E
Lung_rep_2_H&E
Lung_rep_4_H&E

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Spatial pattern pathway has Fam111a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Spinal cord	CN94_E1	2.7e-06
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Spinal cord	CN94_E1	1.9e-06
Fam111a	GOBP_Protein_Maturation	Mouse	Spinal cord	CN94_E1	2.2e-06
Fam111a	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	CN94_E1	5.5e-06
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Spinal cord	L7bCN01_D2	4.3e-06
Fam111a	GOBP_Negative_Regulation_Of_Viral_Genome_Replication	Mouse	Spinal cord	L7CN44_D1	5.0e-06
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Spinal cord	L7CN45_C1	4.8e-07
Fam111a	GOBP_Dna_Repair	Mouse	Spinal cord	L7CN45_C1	9.4e-06
Fam111a	GOBP_Dna_Replication	Mouse	Spinal cord	L7CN45_C1	2.8e-07
Fam111a	GOBP_Negative_Regulation_Of_Viral_Process	Mouse	Spinal cord	L7CN45_C1	4.9e-09
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Spinal cord	L7CN45_C1	2.5e-07
Fam111a	GOBP_Protein_Processing	Mouse	Spinal cord	L7CN45_C1	7.1e-07
Fam111a	GOBP_Proteolysis	Mouse	Spinal cord	L7CN45_C1	1.1e-06
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Spinal cord	L7CN45_C1	2.5e-07
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Spinal cord	L7CN45_C1	5.2e-06
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Spinal cord	L7CN47_C1	6.6e-06
Fam111a	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Spinal cord	L7CN97_E2	6.8e-06
Fam111a	GOBP_Viral_Life_Cycle	Mouse	Spinal cord	L7CN97_E2	7.3e-06
Fam111a	GOBP_Dna_Replication	Mouse	Brain	rep_27	6.4e-06
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Brain	rep_41	5.2e-08
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Brain	rep_41	6.5e-07
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Brain	rep_41	3.9e-09
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Brain	rep_1	1.5e-17
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Brain	rep_1	3.7e-22
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Brain	rep_1	1.1e-07
Fam111a	GOBP_Dna_Replication	Mouse	Brain	rep_1	4.3e-10
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Brain	rep_1	5.9e-07
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Brain	rep_1	6.3e-30
Fam111a	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	rep_3	1.9e-146
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Fam111a	GOBP_Dna_Repair	Mouse	Brain	rep_3	4.0e-216
Fam111a	GOBP_Negative_Regulation_Of_Viral_Process	Mouse	Brain	rep_3	2.0e-102
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Brain	rep_3	4.8e-135
Fam111a	GOBP_Protein_Maturation	Mouse	Brain	rep_3	1.1e-160
Fam111a	GOBP_Protein_Processing	Mouse	Brain	rep_3	2.3e-168
Fam111a	GOBP_Proteolysis	Mouse	Brain	rep_3	1.8e-168
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	rep_3	1.1e-144
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Brain	rep_3	9.0e-141
Fam111a	GOBP_Viral_Life_Cycle	Mouse	Brain	rep_3	8.3e-131
Fam111a	GOBP_Negative_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_6	9.5e-15
Fam111a	GOBP_Negative_Regulation_Of_Viral_Process	Mouse	Embryo	rep_6	3.3e-23
Fam111a	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_6	2.4e-10
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_6	1.2e-12
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Embryo	rep_14	7.3e-18
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Embryo	rep_14	4.9e-15
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Embryo	rep_14	3.2e-68
Fam111a	GOBP_Protein_Maturation	Mouse	Embryo	rep_14	6.3e-10
Fam111a	GOBP_Protein_Processing	Mouse	Embryo	rep_14	4.6e-22
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Embryo	rep_14	3.7e-09
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Embryo	rep_1	0.0e+00
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Embryo	rep_1	0.0e+00
Fam111a	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Embryo	rep_2	7.4e-121
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Embryo	rep_2	7.2e-216
Fam111a	GOBP_Dna_Repair	Mouse	Embryo	rep_2	1.6e-282
Fam111a	GOBP_Viral_Life_Cycle	Mouse	Embryo	rep_4	5.2e-15
Fam111a	GOBP_Protein_Maturation	Mouse	Kidney	IRI	2.5e-33
Fam111a	GOBP_Protein_Processing	Mouse	Kidney	IRI	4.8e-57
Fam111a	GOBP_Proteolysis	Mouse	Kidney	Nep	6.8e-23
Fam111a	GOBP_Protein_Processing	Mouse	Kidney	rep_1	8.0e-08
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Kidney	rep_2	1.1e-109
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Kidney	rep_2	1.5e-19
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-12
Fam111a	GOBP_Dna_Repair	Mouse	Kidney	rep_2	5.5e-70
Fam111a	GOBP_Dna_Replication	Mouse	Kidney	rep_2	5.9e-43
Fam111a	GOBP_Negative_Regulation_Of_Viral_Process	Mouse	Kidney	rep_2	1.7e-35
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Kidney	rep_2	7.5e-67
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Kidney	rep_2	5.9e-36
Fam111a	GOBP_Protein_Maturation	Mouse	Kidney	rep_2	5.4e-103
Fam111a	GOBP_Proteolysis	Mouse	Kidney	rep_2	6.0e-106
Fam111a	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Kidney	rep_2	2.5e-65
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Kidney	rep_2	2.2e-44
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Kidney	rep_2	2.4e-07
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Kidney	rep_2	4.6e-17
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Liver	CN16-D1	3.0e-08
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Liver	CN16-D2	3.1e-08
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Liver	CN16-D2	2.6e-07
Fam111a	GOBP_Negative_Regulation_Of_Viral_Genome_Replication	Mouse	Liver	CN16-D2	2.9e-08
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Liver	CN16-D2	3.0e-07
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Liver	rep_15	2.2e-11
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Liver	rep_16	2.4e-08
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Liver	rep_16	5.5e-14
Fam111a	GOBP_Protein_Maturation	Mouse	Liver	rep_16	4.5e-09
Fam111a	GOBP_Protein_Processing	Mouse	Liver	rep_16	3.8e-09
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Liver	rep_16	3.0e-14
Fam111a	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	4.6e-18
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Lymph	MS-1	3.1e-11
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Lymph	MS-1	6.8e-10
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Lymph	MS-1	8.1e-10
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Lymph	MS-1	7.1e-09
Fam111a	GOBP_Protein_Processing	Mouse	Lymph	MS-1	8.5e-10
Fam111a	GOBP_Proteolysis	Mouse	Lymph	MS-1	2.8e-10
Fam111a	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Lymph	MS-1	3.1e-25
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Lymph	MS-1	1.1e-07
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Lymph	MS-1	6.0e-11
Fam111a	GOBP_Viral_Life_Cycle	Mouse	Lymph	MS-1	5.7e-13
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Lymph	PBS	2.2e-07
Fam111a	GOBP_Negative_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	rep_7	4.5e-26
Fam111a	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Fam111a	GOBP_Dna_Dependent_Dna_Replication	Mouse	Brain	HP_ad_rep7	1.6e-15
Fam111a	GOBP_Dna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	3.1e-11
Fam111a	GOBP_Dna_Repair	Mouse	Brain	HP_ad_rep7	2.4e-12
Fam111a	GOBP_Dna_Replication	Mouse	Brain	HP_ad_rep7	1.1e-10
Fam111a	GOBP_Protein_Dna_Covalent_Cross_Linking_Repair	Mouse	Brain	HP_ad_rep7	1.1e-08
Fam111a	GOBP_Proteolysis	Mouse	Brain	HP_ad_rep7	3.3e-07
Fam111a	GOBP_Regulation_Of_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_ad_rep7	6.6e-21
Fam111a	GOBP_Negative_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	HP_adpolb_rep1	1.0e-08
Fam111a	GOBP_Replication_Fork_Processing	Mouse	Brain	HP_adpolb_rep1	3.0e-07
Fam111a	GOBP_Dna_Dependent_Dna_Replication_Maintenance_Of_Fidelity	Mouse	Brain	HP_polb_rep1	5.3e-07
Fam111a	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Mouse	Brain	HP_polb_rep9	1.1e-12
Fam111a	GOBP_Negative_Regulation_Of_Viral_Process	Mouse	Brain	HP_polb_rep9	1.6e-09
Fam111a	GOBP_Protein_Autoprocessing	Mouse	Brain	HP_polb_rep9	6.8e-11
Fam111a	GOBP_Protein_Maturation	Mouse	Brain	HP_polb_rep9	9.1e-14
Fam111a	GOBP_Protein_Processing	Mouse	Brain	HP_polb_rep9	1.6e-12
Fam111a	GOBP_Regulation_Of_Viral_Genome_Replication	Mouse	Brain	HP_polb_rep9	2.7e-08
Fam111a	GOBP_Viral_Genome_Replication	Mouse	Brain	HP_polb_rep9	9.1e-08
Fam111a	GOBP_Viral_Life_Cycle	Mouse	Brain	HP_polb_rep9	5.6e-08

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Fam111a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Fam111a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Fam111a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Fam111a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Fam111a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
Fam111a	C4316787	Kenny-Caffey syndrome, type 2	3	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
Fam111a	C0265291	Kenny-Caffey syndrome	1	GENOMICS_ENGLAND;ORPHANET
Fam111a	C1865639	Gracile bone dysplasia	1	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT