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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: Vps37c (spascer ID:107305)

Gene summary for Vps37c

check button Gene summary
Gene information
SpeciesMouse
Gene symbol

Vps37c

Gene ID

107305

Gene namevacuolar protein sorting 37C
Synonyms5730409F24Rik|AU042646
Cytomap19|19 A
Type of geneprotein-coding
Descriptionvacuolar protein sorting-associated protein 37CESCRT-I complex subunit VPS37C
Modification date20220424
UniProtAcc

Q8R105


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
Vps37c

GO:0000813

ESCRT I complex

21873635

Component
Vps37c

GO:0006612

protein targeting to membrane

21873635

Process
Vps37c

GO:0006623

protein targeting to vacuole

21873635

Process
Vps37c

GO:0043162

ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

21873635

Process

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Spatial pattern events for Vps37c

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
Vps37cMouseBrainS7 344135151.27e-07
Vps37cMouseKidneyCLP 340037978.56e-06
Vps37cMouseTesticlerep_5 347316002.93e-08

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Kidney_CLP_H&E
boxplot

boxplot


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Spatial pattern pathway has Vps37c envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
Vps37cGOBP_Endosome_OrganizationMouseSpinal cordCN94_E1 1.8e-07
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseSpinal cordCN94_E1 5.0e-06
Vps37cGOBP_Multivesicular_Body_OrganizationMouseSpinal cordCN94_E1 3.2e-06
Vps37cGOBP_Organelle_AssemblyMouseSpinal cordCN94_E1 9.5e-06
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseSpinal cordL7CN45_C1 4.2e-07
Vps37cGOBP_Endomembrane_System_OrganizationMouseSpinal cordL7CN45_C1 1.0e-06
Vps37cGOBP_Endosomal_TransportMouseSpinal cordL7CN45_C1 4.4e-08
Vps37cGOBP_Establishment_Of_Protein_LocalizationMouseSpinal cordL7CN45_C1 4.4e-06
Vps37cGOBP_Intracellular_Protein_TransportMouseSpinal cordL7CN45_C1 3.6e-07
Vps37cGOBP_Intracellular_TransportMouseSpinal cordL7CN45_C1 4.4e-06
Vps37cGOBP_MacroautophagyMouseSpinal cordL7CN45_C1 1.0e-06
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseSpinal cordL7CN45_C1 7.5e-06
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseSpinal cordL7CN45_C1 2.7e-07
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseSpinal cordL7CN45_C1 5.1e-08
Vps37cGOBP_Process_Utilizing_Autophagic_MechanismMouseSpinal cordL7CN45_C1 3.6e-07
Vps37cGOBP_Protein_Catabolic_ProcessMouseSpinal cordL7CN45_C1 5.6e-06
Vps37cGOBP_Protein_Localization_To_OrganelleMouseSpinal cordL7CN45_C1 3.6e-07
Vps37cGOBP_Protein_Localization_To_VacuoleMouseSpinal cordL7CN45_C1 5.2e-07
Vps37cGOBP_Protein_TargetingMouseSpinal cordL7CN45_C1 1.4e-06
Vps37cGOBP_Protein_Targeting_To_MembraneMouseSpinal cordL7CN45_C1 2.9e-06
Vps37cGOBP_ProteolysisMouseSpinal cordL7CN45_C1 1.1e-06
Vps37cGOBP_Vacuolar_TransportMouseSpinal cordL7CN45_C1 5.1e-07
Vps37cGOBP_Vesicle_OrganizationMouseSpinal cordL7CN45_C1 7.6e-07
Vps37cGOBP_Viral_BuddingMouseSpinal cordL7CN45_C1 2.9e-06
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseSpinal cordL7CN47_C1 7.0e-06
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseSpinal cordL7CN47_C1 5.4e-06
Vps37cGOBP_Virion_AssemblyMouseSpinal cordL7CN47_C1 6.2e-06
Vps37cGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseSpinal cordL7CN97_E2 6.8e-06
Vps37cGOBP_Viral_Life_CycleMouseSpinal cordL7CN97_E2 7.3e-06
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseBrainrep_75 2.2e-05
Vps37cGOBP_Endomembrane_System_OrganizationMouseBrainrep_1 7.8e-10
Vps37cGOBP_Endosomal_TransportMouseBrainrep_1 8.9e-24
Vps37cGOBP_Endosome_OrganizationMouseBrainrep_1 6.1e-18
Vps37cGOBP_Establishment_Of_Protein_LocalizationMouseBrainrep_1 6.6e-07
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseBrainrep_1 2.9e-25
Vps37cGOBP_MacroautophagyMouseBrainrep_1 6.7e-14
Vps37cGOBP_Vesicle_OrganizationMouseBrainrep_1 7.9e-37
Vps37cGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainrep_31.9e-146
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseBrainrep_31.6e-125
Vps37cGOBP_Cellular_Protein_Catabolic_ProcessMouseBrainrep_32.9e-162
Vps37cGOBP_Establishment_Of_Protein_Localization_To_OrganelleMouseBrainrep_31.2e-180
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseBrainrep_3 5.5e-77
Vps37cGOBP_Intracellular_Protein_TransportMouseBrainrep_32.7e-132
Vps37cGOBP_Intracellular_TransportMouseBrainrep_31.0e-102
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseBrainrep_31.7e-159
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseBrainrep_38.7e-167
Vps37cGOBP_Multivesicular_Body_OrganizationMouseBrainrep_31.7e-216
Vps37cGOBP_Organelle_AssemblyMouseBrainrep_32.0e-160
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseBrainrep_37.1e-166
Vps37cGOBP_Process_Utilizing_Autophagic_MechanismMouseBrainrep_31.0e-145
Vps37cGOBP_Protein_Catabolic_ProcessMouseBrainrep_33.0e-174
Vps37cGOBP_Protein_Localization_To_OrganelleMouseBrainrep_36.3e-172
Vps37cGOBP_Protein_Localization_To_VacuoleMouseBrainrep_3 5.1e-64
Vps37cGOBP_Protein_TargetingMouseBrainrep_32.9e-187
Vps37cGOBP_Protein_Targeting_To_MembraneMouseBrainrep_31.5e-197
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseBrainrep_3 1.4e-83
Vps37cGOBP_ProteolysisMouseBrainrep_31.8e-168
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseBrainrep_38.0e-209
Vps37cGOBP_Vacuolar_TransportMouseBrainrep_33.9e-136
Vps37cGOBP_Viral_BuddingMouseBrainrep_31.1e-223
Vps37cGOBP_Viral_Life_CycleMouseBrainrep_38.3e-131
Vps37cGOBP_Virion_AssemblyMouseBrainrep_3 3.5e-51
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseEmbryorep_14 1.7e-10
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseEmbryorep_14 6.3e-13
Vps37cGOBP_Multivesicular_Body_OrganizationMouseEmbryorep_14 3.0e-12
Vps37cGOBP_Protein_Localization_To_VacuoleMouseEmbryorep_14 4.4e-11
Vps37cGOBP_Protein_TargetingMouseEmbryorep_14 6.3e-09
Vps37cGOBP_Protein_Targeting_To_MembraneMouseEmbryorep_14 1.4e-25
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseEmbryorep_14 4.2e-10
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseEmbryorep_14 4.5e-32
Vps37cGOBP_Viral_BuddingMouseEmbryorep_14 7.7e-21
Vps37cGOBP_Virion_AssemblyMouseEmbryorep_14 2.4e-07
Vps37cGOBP_Establishment_Of_Protein_Localization_To_OrganelleMouseEmbryorep_1 8.6e-17
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseEmbryorep_1 7.5e-10
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseEmbryorep_1 5.7e-21
Vps37cGOBP_Protein_Catabolic_ProcessMouseEmbryorep_1 4.1e-19
Vps37cGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseEmbryorep_27.4e-121
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseEmbryorep_2 5.5e-15
Vps37cGOBP_Intracellular_Protein_TransportMouseEmbryorep_4 1.1e-39
Vps37cGOBP_Viral_Life_CycleMouseEmbryorep_4 5.2e-15
Vps37cGOBP_Organelle_AssemblyMouseEmbryorep_6 4.1e-70
Vps37cGOBP_ProteolysisMouseKidneyNep 6.8e-23
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseKidneyrep_2 3.5e-61
Vps37cGOBP_Cellular_Protein_Catabolic_ProcessMouseKidneyrep_2 3.2e-21
Vps37cGOBP_Endomembrane_System_OrganizationMouseKidneyrep_21.0e-161
Vps37cGOBP_Endosomal_TransportMouseKidneyrep_21.5e-111
Vps37cGOBP_Endosome_OrganizationMouseKidneyrep_2 7.0e-90
Vps37cGOBP_Establishment_Of_Protein_LocalizationMouseKidneyrep_2 9.8e-86
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseKidneyrep_2 4.7e-11
Vps37cGOBP_Establishment_Of_Protein_Localization_To_OrganelleMouseKidneyrep_2 3.3e-19
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseKidneyrep_29.1e-128
Vps37cGOBP_Intracellular_Protein_TransportMouseKidneyrep_2 7.5e-54
Vps37cGOBP_Intracellular_TransportMouseKidneyrep_2 7.9e-80
Vps37cGOBP_MacroautophagyMouseKidneyrep_2 1.3e-64
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseKidneyrep_2 7.0e-40
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseKidneyrep_2 1.0e-26
Vps37cGOBP_Multivesicular_Body_OrganizationMouseKidneyrep_2 7.8e-74
Vps37cGOBP_Organelle_AssemblyMouseKidneyrep_2 2.8e-62
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseKidneyrep_2 1.2e-14
Vps37cGOBP_Process_Utilizing_Autophagic_MechanismMouseKidneyrep_2 1.8e-66
Vps37cGOBP_Protein_Catabolic_ProcessMouseKidneyrep_2 7.3e-30
Vps37cGOBP_Protein_Localization_To_OrganelleMouseKidneyrep_2 3.4e-44
Vps37cGOBP_Protein_Localization_To_VacuoleMouseKidneyrep_21.1e-140
Vps37cGOBP_Protein_TargetingMouseKidneyrep_2 1.7e-40
Vps37cGOBP_Protein_Targeting_To_MembraneMouseKidneyrep_2 2.4e-30
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseKidneyrep_21.3e-130
Vps37cGOBP_ProteolysisMouseKidneyrep_26.0e-106
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseKidneyrep_2 2.1e-37
Vps37cGOBP_Vacuolar_TransportMouseKidneyrep_2 5.2e-99
Vps37cGOBP_Vesicle_OrganizationMouseKidneyrep_2 6.0e-62
Vps37cGOBP_Viral_BuddingMouseKidneyrep_2 7.0e-85
Vps37cGOBP_Virion_AssemblyMouseKidneyrep_27.6e-139
Vps37cGOBP_Endosome_OrganizationMouseLiverCN16-D2 1.5e-07
Vps37cGOBP_Protein_Targeting_To_MembraneMouseLiverCN16-D2 6.1e-07
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseLiverCN16-E1 7.5e-07
Vps37cGOBP_Multivesicular_Body_OrganizationMouseLiverCN16-E1 4.3e-12
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseLiverCN16-E1 1.5e-07
Vps37cGOBP_Multivesicular_Body_OrganizationMouseLiverrep_15 2.8e-08
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseLiverrep_15 4.8e-16
Vps37cGOBP_Viral_BuddingMouseLiverrep_15 9.8e-09
Vps37cGOBP_Virion_AssemblyMouseLiverrep_16 7.7e-10
Vps37cGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseLymphMS-1 4.6e-18
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseLymphMS-1 1.1e-11
Vps37cGOBP_Cellular_Protein_Catabolic_ProcessMouseLymphMS-1 1.1e-11
Vps37cGOBP_Endomembrane_System_OrganizationMouseLymphMS-1 2.5e-09
Vps37cGOBP_Endosomal_TransportMouseLymphMS-1 9.8e-11
Vps37cGOBP_Endosome_OrganizationMouseLymphMS-1 4.4e-09
Vps37cGOBP_Establishment_Of_Protein_LocalizationMouseLymphMS-1 2.5e-11
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseLymphMS-1 1.3e-10
Vps37cGOBP_Establishment_Of_Protein_Localization_To_OrganelleMouseLymphMS-1 3.3e-11
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseLymphMS-1 6.0e-08
Vps37cGOBP_Intracellular_Protein_TransportMouseLymphMS-1 3.0e-17
Vps37cGOBP_Intracellular_TransportMouseLymphMS-1 3.3e-11
Vps37cGOBP_MacroautophagyMouseLymphMS-1 3.3e-11
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseLymphMS-1 1.2e-13
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseLymphMS-1 1.1e-11
Vps37cGOBP_Multivesicular_Body_OrganizationMouseLymphMS-1 3.5e-09
Vps37cGOBP_Organelle_AssemblyMouseLymphMS-1 5.5e-08
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseLymphMS-1 1.2e-13
Vps37cGOBP_Process_Utilizing_Autophagic_MechanismMouseLymphMS-1 3.9e-13
Vps37cGOBP_Protein_Catabolic_ProcessMouseLymphMS-1 1.1e-11
Vps37cGOBP_Protein_Localization_To_OrganelleMouseLymphMS-1 1.4e-09
Vps37cGOBP_Protein_Localization_To_VacuoleMouseLymphMS-1 1.5e-07
Vps37cGOBP_Protein_TargetingMouseLymphMS-1 2.1e-09
Vps37cGOBP_Protein_Targeting_To_MembraneMouseLymphMS-1 3.9e-09
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseLymphMS-1 4.4e-08
Vps37cGOBP_ProteolysisMouseLymphMS-1 2.8e-10
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseLymphMS-1 2.5e-11
Vps37cGOBP_Vacuolar_TransportMouseLymphMS-1 1.1e-08
Vps37cGOBP_Vesicle_OrganizationMouseLymphMS-1 1.9e-12
Vps37cGOBP_Viral_BuddingMouseLymphMS-1 4.3e-12
Vps37cGOBP_Viral_Life_CycleMouseLymphMS-1 5.7e-13
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseLungrep_1 2.0e-21
Vps37cGOBP_Endosomal_TransportMouseBrainrep_4 2.6e-13
Vps37cGOBP_Vesicle_OrganizationMouseBrainrep_4 7.9e-08
Vps37cGOBP_Cellular_Macromolecule_LocalizationMouseBrainHP_ad_rep7 6.6e-10
Vps37cGOBP_Endosome_OrganizationMouseBrainHP_ad_rep7 3.1e-08
Vps37cGOBP_Establishment_Of_Protein_LocalizationMouseBrainHP_ad_rep7 8.7e-10
Vps37cGOBP_Establishment_Of_Protein_Localization_To_OrganelleMouseBrainHP_ad_rep7 6.1e-09
Vps37cGOBP_Establishment_Of_Protein_Localization_To_VacuoleMouseBrainHP_ad_rep7 6.0e-10
Vps37cGOBP_Intracellular_Protein_TransportMouseBrainHP_ad_rep7 3.6e-08
Vps37cGOBP_Intracellular_TransportMouseBrainHP_ad_rep7 3.1e-08
Vps37cGOBP_MacroautophagyMouseBrainHP_ad_rep7 1.6e-07
Vps37cGOBP_Macromolecule_Catabolic_ProcessMouseBrainHP_ad_rep7 1.3e-09
Vps37cGOBP_Modification_Dependent_Macromolecule_Catabolic_ProcessMouseBrainHP_ad_rep7 1.3e-08
Vps37cGOBP_Multivesicular_Body_OrganizationMouseBrainHP_ad_rep7 5.5e-07
Vps37cGOBP_Organonitrogen_Compound_Catabolic_ProcessMouseBrainHP_ad_rep7 3.3e-07
Vps37cGOBP_Process_Utilizing_Autophagic_MechanismMouseBrainHP_ad_rep7 3.5e-08
Vps37cGOBP_Protein_Catabolic_ProcessMouseBrainHP_ad_rep7 3.3e-07
Vps37cGOBP_Protein_Localization_To_OrganelleMouseBrainHP_ad_rep7 4.8e-12
Vps37cGOBP_Protein_Targeting_To_MembraneMouseBrainHP_ad_rep7 1.1e-09
Vps37cGOBP_Protein_Targeting_To_VacuoleMouseBrainHP_ad_rep7 2.5e-11
Vps37cGOBP_ProteolysisMouseBrainHP_ad_rep7 3.3e-07
Vps37cGOBP_Ubiquitin_Dependent_Protein_Catabolic_Process_Via_The_Multivesicular_Body_Sorting_PathwayMouseBrainHP_ad_rep7 4.7e-15
Vps37cGOBP_Vacuolar_TransportMouseBrainHP_ad_rep7 1.2e-09
Vps37cGOBP_Viral_BuddingMouseBrainHP_ad_rep7 2.0e-14
Vps37cGOBP_Virion_AssemblyMouseBrainHP_ad_rep7 2.3e-09
Vps37cGOBP_Cellular_Protein_Catabolic_ProcessMouseBrainHP_adpolb_rep1 7.2e-07
Vps37cGOBP_Organelle_AssemblyMouseBrainHP_adpolb_rep1 1.8e-07
Vps37cGOBP_Biological_Process_Involved_In_Symbiotic_InteractionMouseBrainHP_polb_rep9 1.1e-12
Vps37cGOBP_Endomembrane_System_OrganizationMouseBrainHP_polb_rep9 6.0e-11
Vps37cGOBP_Endosomal_TransportMouseBrainHP_polb_rep9 2.8e-14
Vps37cGOBP_Establishment_Of_Protein_Localization_To_MembraneMouseBrainHP_polb_rep9 3.1e-10
Vps37cGOBP_Protein_Localization_To_VacuoleMouseBrainHP_polb_rep9 1.3e-10
Vps37cGOBP_Protein_TargetingMouseBrainHP_polb_rep9 1.8e-11
Vps37cGOBP_Vesicle_OrganizationMouseBrainHP_polb_rep9 4.1e-14
Vps37cGOBP_Viral_Life_CycleMouseBrainHP_polb_rep9 5.6e-08

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Vps37c function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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Vps37c function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for Vps37c envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for Vps37c

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for Vps37c

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource