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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Yars (spascer ID:107271)

Gene summary for Yars

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Yars
	Gene ID	107271
	Gene name	tyrosyl-tRNA synthetase
	Synonyms	AL024047\|AU018965\|Yars1
	Cytomap	4\|4 D2.2
	Type of gene	protein-coding
	Description	tyrosine--tRNA ligase, cytoplasmictyrRStyrosyl--tRNA ligasetyrosyl-tRNA synthetase, cytoplasmic
	Modification date	20220424
	UniProtAcc	Q91WQ3

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Yars	GO:0004831	tyrosine-tRNA ligase activity	21873635	Function

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Spatial pattern events for Yars

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Yars	Mouse	Brain	S3	34413515	2.96e-15
Yars	Mouse	Brain	S4	34413515	2.43e-15
Yars	Mouse	Brain	rep_1	35141374	6.80e-15
Yars	Mouse	Brain	rep_2	35141374	5.75e-15
Yars	Mouse	Brain	rep_3	35141374	4.80e-08
Yars	Mouse	Brain	rep_4	35141374	1.57e-15
Yars	Mouse	Brain	rep_5	35141374	5.13e-15
Yars	Mouse	Brain	rep_6	35141374	1.82e-08
Yars	Mouse	Embryo	1G	34210887	1.01e-14
Yars	Mouse	Kidney	CLP	34003797	3.77e-15
Yars	Mouse	Kidney	IRI	34003797	3.92e-15
Yars	Mouse	Kidney	Sham	34003797	2.58e-15
Yars	Mouse	Kidney	rep_4	34853151	4.37e-09
Yars	Mouse	Brain	rep_1	33469025	4.52e-15
Yars	Mouse	Brain	rep_1	35027729	4.52e-12
Yars	Mouse	Brain	rep_2	35027729	2.83e-15
Yars	Mouse	Brain	rep_3	35027729	1.32e-15
Yars	Mouse	Brain	rep_4	35027729	6.67e-07
Yars	Mouse	Brain	rep_5	35027729	5.00e-15
Yars	Mouse	Intestine	rep_2	35149721	3.67e-07
Yars	Mouse	Lymph	A1	0	3.24e-14
Yars	Mouse	Lymph	B1	0	6.08e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_4_H&E
Brain_rep_1_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Yars envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.5e-07
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Spinal cord	L7bCN02_E1	7.1e-06
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	2.2e-09
Yars	GOBP_Amino_Acid_Activation	Mouse	Spinal cord	L7CN45_C1	1.9e-07
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.5e-07
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	3.5e-08
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.4e-09
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Yars	GOBP_Trna_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	4.6e-07
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	rep_3	2.5e-86
Yars	GOBP_Amino_Acid_Activation	Mouse	Brain	rep_3	5.9e-107
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	rep_3	2.1e-87
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_3	8.5e-191
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	rep_3	1.8e-46
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	rep_3	1.5e-154
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	rep_3	2.1e-69
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Brain	rep_3	1.3e-86
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Yars	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_3	2.5e-229
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Embryo	rep_14	3.7e-18
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Embryo	rep_14	2.8e-15
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Embryo	rep_14	4.7e-16
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Embryo	rep_3	9.9e-51
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Embryo	rep_3	1.4e-07
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Kidney	rep_2	1.9e-84
Yars	GOBP_Amino_Acid_Activation	Mouse	Kidney	rep_2	4.4e-95
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-85
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-34
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Kidney	rep_2	6.2e-81
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-62
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Kidney	rep_2	2.9e-85
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Kidney	rep_2	1.4e-80
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Yars	GOBP_Trna_Metabolic_Process	Mouse	Kidney	rep_2	1.9e-92
Yars	GOBP_Amino_Acid_Activation	Mouse	Liver	CN65-C1	4.2e-10
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Liver	CN73-C1	1.4e-08
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Lymph	MS-1	1.3e-09
Yars	GOBP_Amino_Acid_Activation	Mouse	Lymph	MS-1	1.4e-08
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-13
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Lymph	MS-1	1.3e-15
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Lymph	MS-1	7.1e-07
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Lymph	MS-1	5.8e-11
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Yars	GOBP_Trna_Metabolic_Process	Mouse	Lymph	MS-1	1.0e-08
Yars	GOBP_Amino_Acid_Activation	Mouse	Brain	rep_4	9.9e-142
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	rep_4	1.9e-21
Yars	GOBP_Trna_Metabolic_Process	Mouse	Brain	rep_4	2.6e-107
Yars	GOBP_Amide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	8.0e-10
Yars	GOBP_Cellular_Amide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.6e-11
Yars	GOBP_Cellular_Amino_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	1.0e-14
Yars	GOBP_Ncrna_Metabolic_Process	Mouse	Brain	HP_ad_rep7	5.9e-10
Yars	GOBP_Organic_Acid_Metabolic_Process	Mouse	Brain	HP_ad_rep7	4.1e-08
Yars	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Yars	GOBP_Peptide_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	4.4e-10
Yars	GOBP_Peptide_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.8e-10
Yars	GOBP_Trna_Metabolic_Process	Mouse	Brain	HP_adpolb_rep5	9.9e-10
Yars	GOBP_Amino_Acid_Activation	Mouse	Brain	HP_polb_rep9	9.7e-14
Yars	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Yars function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Yars function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Yars envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Yars

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Yars

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source