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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Macrod1 (spascer ID:107227)

Gene summary for Macrod1

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Macrod1
	Gene ID	107227
	Gene name	mono-ADP ribosylhydrolase 1
	Synonyms	AI604841\|AW743046\|D930010J01Rik\|Lrp16
	Cytomap	19\|19 A
	Type of gene	protein-coding
	Description	ADP-ribose glycohydrolase MACROD1MACRO domain containing 1MACRO domain-containing protein 1O-acetyl-ADP-ribose deacetylase MACROD1[Protein ADP-ribosylaspartate] hydrolase MACROD1[Protein ADP-ribosylglutamate] hydrolase[Protein ADP-ribosylglutamate]
	Modification date	20220428
	UniProtAcc	Q922B1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Macrod1	GO:0005654	nucleoplasm	21873635	Component
Macrod1	GO:0006974	cellular response to DNA damage stimulus	21873635	Process
Macrod1	GO:0042278	purine nucleoside metabolic process	21873635	Process
Macrod1	GO:0140291	peptidyl-glutamate ADP-deribosylation	21873635	Process
Macrod1	GO:0140293	ADP-ribosylglutamate hydrolase activity	21873635	Function

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Spatial pattern events for Macrod1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Macrod1	Mouse	Brain	S2	34413515	3.37e-07
Macrod1	Mouse	Brain	S3	34413515	1.64e-15
Macrod1	Mouse	Brain	S4	34413515	1.37e-15
Macrod1	Mouse	Brain	S6	34413515	1.58e-13
Macrod1	Mouse	Brain	rep_1	35141374	2.68e-14
Macrod1	Mouse	Brain	rep_2	35141374	3.05e-15
Macrod1	Mouse	Brain	rep_4	35141374	1.57e-15
Macrod1	Mouse	Brain	rep_5	35141374	1.47e-15
Macrod1	Mouse	Kidney	CLP	34003797	2.19e-15
Macrod1	Mouse	Kidney	IRI	34003797	2.29e-15
Macrod1	Mouse	Kidney	Sham	34003797	2.58e-15
Macrod1	Mouse	Kidney	rep_1	34853151	4.13e-15
Macrod1	Mouse	Kidney	rep_3	34853151	2.94e-15
Macrod1	Mouse	Liver	rep_22	35021063	2.89e-08
Macrod1	Mouse	Brain	rep_1	35027729	2.47e-09
Macrod1	Mouse	Brain	rep_3	35027729	2.38e-15
Macrod1	Mouse	Brain	rep_5	35027729	2.62e-15
Macrod1	Mouse	Lymph	B1	0	6.47e-07

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E
Kidney_CLP_H&E
Kidney_IRI_H&E
Kidney_Sham_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Liver_rep_22_H&E
Brain_rep_1_H&E
Brain_rep_3_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Macrod1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Spinal cord	CN94_E1	8.0e-06
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Spinal cord	CN94_E1	5.7e-06
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.8e-07
Macrod1	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.1e-07
Macrod1	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.7e-07
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN47_C1	3.1e-06
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Spinal cord	L7CN47_D1	6.1e-06
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Spinal cord	L7CN54_D1	6.4e-11
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Brain	rep_27	1.0e-06
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Brain	rep_37	5.7e-05
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Brain	rep_41	9.0e-05
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Brain	rep_1	3.0e-14
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	rep_3	4.5e-61
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	rep_3	5.0e-192
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Brain	rep_3	6.3e-185
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Brain	rep_3	4.7e-175
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Brain	rep_3	2.5e-95
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Embryo	rep_6	1.1e-07
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Embryo	rep_14	8.9e-49
Macrod1	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_14	1.8e-12
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Embryo	rep_14	1.2e-44
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Embryo	rep_14	7.4e-58
Macrod1	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	6.5e-20
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Embryo	rep_2	1.4e-08
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-42
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Kidney	rep_2	5.5e-146
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Kidney	rep_2	3.8e-153
Macrod1	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	2.4e-27
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Kidney	rep_2	3.7e-100
Macrod1	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-17
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Kidney	rep_2	7.0e-77
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Liver	CN16-D2	7.8e-07
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Liver	CN16-E1	5.0e-07
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Liver	CN73-C1	5.1e-08
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Liver	rep_15	9.3e-30
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Lymph	MS-1	2.8e-10
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Lymph	MS-1	8.5e-13
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-10
Macrod1	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.7e-09
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Macrod1	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	8.0e-08
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Lymph	MS-1	1.4e-09
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Brain	rep_4	7.4e-11
Macrod1	GOBP_Protein_De_Adp_Ribosylation	Mouse	Brain	HP_ad_rep3	7.9e-11
Macrod1	GOBP_Purine_Nucleoside_Metabolic_Process	Mouse	Brain	HP_ad_rep3	3.7e-07
Macrod1	GOBP_Cellular_Response_To_Dna_Damage_Stimulus	Mouse	Brain	HP_ad_rep7	6.8e-10
Macrod1	GOBP_Glycosyl_Compound_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.0e-09
Macrod1	GOBP_Nucleoside_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.1e-11
Macrod1	GOBP_Carbohydrate_Derivative_Metabolic_Process	Mouse	Brain	HP_polb_rep9	5.2e-12
Macrod1	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	6.9e-09
Macrod1	GOBP_Purine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	9.4e-07
Macrod1	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Macrod1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Macrod1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Macrod1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Macrod1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Macrod1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source