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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Pnpo (spascer ID:103711)

Gene summary for Pnpo

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Pnpo
	Gene ID	103711
	Gene name	pyridoxine 5'-phosphate oxidase
	Synonyms	AI415282
	Cytomap	11\|11 D
	Type of gene	protein-coding
	Description	pyridoxine-5'-phosphate oxidasepyridoxamine-phosphate oxidase
	Modification date	20220424
	UniProtAcc	Q91XF0

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Pnpo	GO:0004733	pyridoxamine-phosphate oxidase activity	21873635	Function
Pnpo	GO:0042823	pyridoxal phosphate biosynthetic process	21873635	Process

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Spatial pattern events for Pnpo

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Pnpo	Mouse	Brain	S1	34413515	2.07e-15
Pnpo	Mouse	Brain	S2	34413515	1.56e-15
Pnpo	Mouse	Brain	S3	34413515	2.40e-07
Pnpo	Mouse	Brain	S4	34413515	1.24e-06
Pnpo	Mouse	Brain	S6	34413515	1.46e-15
Pnpo	Mouse	Brain	S7	34413515	1.55e-15
Pnpo	Mouse	Brain	rep_1	35141374	8.33e-09
Pnpo	Mouse	Brain	rep_2	35141374	6.38e-08
Pnpo	Mouse	Brain	rep_3	35141374	2.25e-14
Pnpo	Mouse	Brain	rep_4	35141374	1.11e-07
Pnpo	Mouse	Brain	rep_6	35141374	2.28e-10
Pnpo	Mouse	Embryo	rep_4	33188776	5.08e-15
Pnpo	Mouse	Kidney	CLP	34003797	7.37e-09
Pnpo	Mouse	Kidney	rep_1	34853151	9.36e-07
Pnpo	Mouse	Kidney	rep_3	34853151	1.32e-06
Pnpo	Mouse	Brain	rep_1	33469025	7.75e-09
Pnpo	Mouse	Liver	rep_21	35021063	1.44e-09
Pnpo	Mouse	Brain	rep_1	35027729	1.42e-10
Pnpo	Mouse	Brain	rep_2	35027729	1.53e-07
Pnpo	Mouse	Brain	rep_4	35027729	5.87e-15
Pnpo	Mouse	Brain	rep_5	35027729	9.49e-08
Pnpo	Mouse	Intestine	rep_1	35149721	1.09e-06
Pnpo	Mouse	Intestine	rep_2	35149721	3.44e-15
Pnpo	Mouse	Intestine	rep_3	35149721	1.78e-06
Pnpo	Mouse	Intestine	rep_4	35149721	2.30e-15
Pnpo	Mouse	Brain	rep_1	35210624	5.84e-14
Pnpo	Mouse	Brain	rep_2	35210624	1.74e-15
Pnpo	Mouse	Brain	rep_3	35210624	2.00e-08
Pnpo	Mouse	Brain	rep_5	35210624	1.77e-08
Pnpo	Mouse	Brain	rep_7	35210624	8.08e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_3_H&E
Brain_rep_4_H&E
Brain_rep_6_H&E
Kidney_CLP_H&E
Kidney_rep_1_H&E
Kidney_rep_3_H&E
Brain_rep_1_H&E
Liver_rep_21_H&E
Brain_rep_1_H&E
Brain_rep_2_H&E
Brain_rep_4_H&E
Brain_rep_5_H&E

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Spatial pattern pathway has Pnpo envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Spinal cord	CN93_D2	4.3e-06
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	4.5e-06
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Spinal cord	CN94_E1	5.3e-06
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Spinal cord	L7CN32_C1	1.5e-06
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Spinal cord	L7CN32_D2	2.7e-06
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	5.5e-07
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	3.0e-06
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	5.6e-08
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	2.0e-07
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Spinal cord	L7CN45_C1	4.3e-07
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.7e-07
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.4e-06
Pnpo	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Spinal cord	L7CN45_C1	1.2e-07
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Spinal cord	L7CN85_E1	4.1e-08
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	rep_11	1.1e-05
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	rep_21	6.6e-05
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Brain	rep_71	6.7e-05
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Brain	rep_71	1.1e-05
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Brain	rep_3	4.9e-47
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	rep_3	4.2e-133
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	5.0e-126
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-144
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Brain	rep_3	2.9e-25
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	rep_3	8.1e-43
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Brain	rep_3	9.3e-98
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Brain	rep_3	1.8e-150
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-103
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	rep_3	2.7e-19
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Brain	rep_3	5.2e-140
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Brain	rep_3	1.1e-118
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	rep_3	2.6e-174
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Brain	rep_3	1.7e-136
Pnpo	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Brain	rep_3	5.9e-186
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Embryo	rep_6	2.1e-13
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Embryo	rep_6	6.6e-12
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Embryo	rep_6	7.4e-20
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Embryo	rep_6	1.0e-11
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Embryo	rep_14	2.9e-38
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Embryo	rep_14	3.1e-12
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	2.4e-12
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Embryo	rep_14	1.8e-11
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Embryo	rep_14	2.0e-09
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Embryo	rep_14	3.6e-92
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Embryo	rep_14	7.5e-67
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_14	6.9e-13
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Embryo	rep_14	8.7e-66
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Embryo	rep_14	6.7e-44
Pnpo	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Embryo	rep_14	7.1e-79
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Embryo	rep_1	7.1e-68
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Embryo	rep_1	8.4e-169
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Embryo	rep_1	1.4e-55
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Embryo	rep_4	6.0e-12
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Kidney	rep_2	1.4e-100
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Kidney	rep_2	3.4e-67
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	6.5e-91
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Kidney	rep_2	2.5e-90
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	8.9e-78
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Kidney	rep_2	1.2e-09
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Kidney	rep_2	1.7e-41
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Kidney	rep_2	1.2e-41
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Kidney	rep_2	1.6e-68
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Kidney	rep_2	1.8e-73
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Kidney	rep_2	1.8e-43
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Kidney	rep_2	1.6e-88
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Kidney	rep_2	4.2e-146
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Kidney	rep_2	6.7e-44
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Kidney	rep_2	5.4e-108
Pnpo	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Kidney	rep_2	6.8e-65
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Liver	CN16-D1	8.4e-14
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Liver	CN16-E1	4.8e-10
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Liver	CN16-E1	5.4e-16
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Liver	CN16-E1	3.4e-08
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Liver	CN16-E1	1.7e-10
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Liver	CN73-C1	9.8e-08
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Liver	CN73-C1	2.1e-07
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Liver	CN73-C1	3.0e-11
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Liver	rep_16	8.0e-08
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Intestine	rep_2	1.6e-22
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Intestine	rep_2	7.7e-15
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Intestine	rep_2	9.0e-52
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Intestine	rep_2	1.1e-73
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Intestine	rep_3	7.8e-24
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Lymph	MS-1	6.4e-11
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-13
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	3.1e-07
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	1.4e-09
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Lymph	MS-1	6.7e-07
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Lymph	MS-1	7.3e-07
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Lymph	MS-1	7.2e-12
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Lymph	MS-1	4.4e-12
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Lymph	MS-1	3.0e-17
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Lymph	MS-1	2.6e-11
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Lymph	MS-1	6.2e-08
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Lymph	MS-1	8.0e-09
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Brain	rep_4	5.5e-20
Pnpo	GOBP_Vitamin_B6_Metabolic_Process	Mouse	Brain	HP_ad_rep3	1.1e-13
Pnpo	GOBP_Vitamin_Biosynthetic_Process	Mouse	Brain	HP_ad_rep3	6.1e-09
Pnpo	GOBP_Vitamin_Metabolic_Process	Mouse	Brain	HP_ad_rep3	1.3e-07
Pnpo	GOBP_Water_Soluble_Vitamin_Biosynthetic_Process	Mouse	Brain	HP_ad_rep3	5.9e-14
Pnpo	GOBP_Aldehyde_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	7.0e-13
Pnpo	GOBP_Organic_Hydroxy_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.9e-10
Pnpo	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	2.8e-08
Pnpo	GOBP_Organophosphate_Biosynthetic_Process	Mouse	Brain	HP_ad_rep7	3.2e-11
Pnpo	GOBP_Water_Soluble_Vitamin_Metabolic_Process	Mouse	Brain	HP_ad_rep7	2.1e-08
Pnpo	GOBP_Pyridine_Containing_Compound_Biosynthetic_Process	Mouse	Brain	HP_adpolb_rep1	1.8e-07
Pnpo	GOBP_Pyridine_Containing_Compound_Metabolic_Process	Mouse	Brain	HP_adpolb_rep1	1.9e-07
Pnpo	GOBP_Cellular_Aldehyde_Metabolic_Process	Mouse	Brain	HP_adpolb_rep3	5.5e-07
Pnpo	GOBP_Organic_Hydroxy_Compound_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.0e-07
Pnpo	GOBP_Organophosphate_Metabolic_Process	Mouse	Brain	HP_polb_rep9	7.1e-09
Pnpo	GOBP_Small_Molecule_Biosynthetic_Process	Mouse	Brain	HP_polb_rep9	2.8e-11
Pnpo	GOBP_Small_Molecule_Metabolic_Process	Mouse	Brain	HP_polb_rep9	2.0e-09

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Pnpo function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Pnpo function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Pnpo envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Pnpo

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Pnpo

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source