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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: Dennd4a (spascer ID:102442)

Gene summary for Dennd4a

Gene summary

Gene information
	Species	Mouse
	Gene symbol	Dennd4a
	Gene ID	102442
	Gene name	DENN/MADD domain containing 4A
	Synonyms	AI115600\|AI851943\|F730015K02Rik
	Cytomap	9\|9 C
	Type of gene	protein-coding
	Description	C-myc promoter-binding protein
	Modification date	20220514
	UniProtAcc

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
Dennd4a	GO:0031410	cytoplasmic vesicle	21873635	Component
Dennd4a	GO:0032483	regulation of Rab protein signal transduction	21873635	Process

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Spatial pattern events for Dennd4a

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
Dennd4a	Mouse	Brain	rep_4	35141374	2.74e-06
Dennd4a	Mouse	Brain	rep_5	35141374	3.85e-11
Dennd4a	Mouse	Embryo	1F	34210887	7.91e-15
Dennd4a	Mouse	Embryo	2G	34210887	4.18e-07
Dennd4a	Mouse	Embryo	2H	34210887	5.31e-15
Dennd4a	Mouse	Embryo	3G	34210887	3.03e-07
Dennd4a	Mouse	Embryo	4D	34210887	1.65e-13
Dennd4a	Mouse	Brain	rep_3	35027729	4.90e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Brain_rep_4_H&E
Brain_rep_5_H&E
Brain_rep_3_H&E

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Spatial pattern pathway has Dennd4a envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Spinal cord	L7CN45_C1	5.6e-06
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Spinal cord	L7CN45_E1	6.5e-07
Dennd4a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Spinal cord	L8CN11_D1	5.6e-09
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Spinal cord	L8CN17_E1	6.9e-06
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_27	7.4e-05
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_27	3.9e-05
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_27	6.4e-05
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_34	2.7e-07
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_1	2.8e-34
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_1	1.1e-11
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_1	3.9e-56
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.2e-13
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_1	5.1e-22
Dennd4a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	rep_3	1.3e-132
Dennd4a	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_3	8.3e-130
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Embryo	rep_6	3.9e-10
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Embryo	rep_14	6.8e-07
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Embryo	rep_3	5.2e-68
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Kidney	rep_2	4.5e-29
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	3.5e-92
Dennd4a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Kidney	rep_2	1.4e-17
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Kidney	rep_2	5.7e-10
Dennd4a	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Kidney	rep_2	4.4e-65
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.0e-93
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Kidney	rep_2	1.2e-75
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Liver	CN16-D2	1.3e-07
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Liver	rep_15	9.0e-08
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	1.1e-08
Dennd4a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Lymph	MS-1	1.0e-14
Dennd4a	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Lymph	MS-1	3.8e-08
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Lymph	MS-1	3.5e-10
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_4	1.1e-10
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Brain	rep_4	4.2e-64
Dennd4a	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	rep_4	1.0e-16
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	rep_4	6.8e-16
Dennd4a	GOBP_Rab_Protein_Signal_Transduction	Mouse	Brain	HP_ad_rep7	1.6e-16
Dennd4a	GOBP_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_ad_rep7	4.6e-08
Dennd4a	GOBP_Regulation_Of_Rab_Protein_Signal_Transduction	Mouse	Brain	HP_adpolb_rep1	1.1e-07
Dennd4a	GOBP_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	7.2e-09
Dennd4a	GOBP_Regulation_Of_Intracellular_Signal_Transduction	Mouse	Brain	HP_polb_rep9	3.9e-11
Dennd4a	GOBP_Regulation_Of_Ras_Protein_Signal_Transduction	Mouse	Brain	HP_polb_rep9	4.3e-10
Dennd4a	GOBP_Regulation_Of_Small_Gtpase_Mediated_Signal_Transduction	Mouse	Brain	HP_polb_rep9	5.2e-07

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Dennd4a function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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Dennd4a function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for Dennd4a envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for Dennd4a

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for Dennd4a

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source