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Spatial pattern gene: IGSF8 (spascer ID:93185) |
Gene summary for IGSF8 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | IGSF8 | Gene ID | 93185 |
| Gene name | immunoglobulin superfamily member 8 |
| Synonyms | CD316|CD81P3|EWI-2|EWI2|KCT-4|LIR-D1|PGRL |
| Cytomap | 1q23.2 |
| Type of gene | protein-coding |
| Description | immunoglobulin superfamily member 8CD81 partner 3glu-Trp-Ile EWI motif-containing protein 2keratinocytes-associated transmembrane protein 4prostaglandin regulatory-like protein |
| Modification date | 20220515 |
| UniProtAcc | Q969P0 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| IGSF8 | GO:0016021 | integral component of membrane | 21873635 | Component |
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Spatial pattern events for IGSF8 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| IGSF8 | Human | Brain | rep_9 | 33558695 | 1.01e-14 |
| IGSF8 | Human | Brain | rep_10 | 33558695 | 6.47e-07 |
| IGSF8 | Human | Brain | rep_11 | 33558695 | 1.78e-11 |
| IGSF8 | Human | Brain | rep_12 | 33558695 | 6.54e-15 |
| IGSF8 | Human | Bladder | rep_2 | 34385456 | 3.04e-08 |
| IGSF8 | Human | Intestine | rep_colon1 | 34417225 | 9.56e-10 |
| IGSF8 | Human | Liver | rep_liver1 | 34417225 | 1.38e-13 |
| IGSF8 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| IGSF8 | Human | Uterus | rep_2 | 34857954 | 9.52e-06 |
| IGSF8 | Human | Breast | 1142243F | 34493872 | 2.30e-10 |
| IGSF8 | Human | Breast | 1160920F | 34493872 | 2.06e-07 |
| IGSF8 | Human | Breast | CID44971 | 34493872 | 2.64e-11 |
| IGSF8 | Human | Breast | CID4535 | 34493872 | 6.37e-15 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_9_H&E  |  |
Brain_rep_10_H&E  |  |
Brain_rep_11_H&E  |  |
Brain_rep_12_H&E  |  |
Bladder_rep_2_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Uterus_rep_2_H&E  |  |
Breast_1142243F_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID44971_H&E  |  |
Breast_CID4535_H&E  |  |
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Spatial pattern pathway has IGSF8 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| IGSF8 | GOBP_Locomotion | Human | Brain | rep_1 | 3.1e-68 |
| IGSF8 | GOBP_Locomotion | Human | Liver | rep_1 | 1.9e-71 |
| IGSF8 | GOBP_Locomotion | Human | Intestine | rep_liver2 | 1.0e-64 |
| IGSF8 | GOBP_Fertilization | Human | Intestine | A3 | 1.8e-11 |
| IGSF8 | GOBP_Locomotion | Human | Intestine | A3 | 1.9e-08 |
| IGSF8 | GOBP_Reproduction | Human | Intestine | A3 | 4.6e-19 |
| IGSF8 | GOBP_Single_Fertilization | Human | Intestine | A3 | 2.8e-12 |
| IGSF8 | GOBP_Skeletal_Muscle_Organ_Development | Human | Intestine | A8 | 2.2e-39 |
| IGSF8 | GOBP_Skeletal_Muscle_Organ_Development | Human | Uterus | rep_25 | 7.4e-10 |
| IGSF8 | GOBP_Fertilization | Human | Uterus | rep_26 | 8.7e-10 |
| IGSF8 | GOBP_Muscle_Organ_Development | Human | Uterus | rep_26 | 6.5e-08 |
| IGSF8 | GOBP_Muscle_Tissue_Development | Human | Uterus | rep_26 | 1.2e-10 |
| IGSF8 | GOBP_Locomotion | Human | Breast | rep_1 | 4.5e-54 |
| IGSF8 | GOBP_Muscle_Organ_Development | Human | Breast | rep_1 | 1.5e-42 |
| IGSF8 | GOBP_Muscle_Structure_Development | Human | Breast | rep_1 | 6.8e-61 |
| IGSF8 | GOBP_Muscle_Tissue_Development | Human | Breast | rep_1 | 1.0e-09 |
| IGSF8 | GOBP_Reproduction | Human | Breast | rep_5 | 8.1e-06 |
| IGSF8 | GOBP_Single_Fertilization | Human | Breast | rep_5 | 1.0e-04 |
| IGSF8 | GOBP_Skeletal_Muscle_Organ_Development | Human | Breast | rep_5 | 5.2e-09 |
| IGSF8 | GOBP_Fertilization | Human | Breast | rep_6 | 1.9e-11 |
| IGSF8 | GOBP_Skeletal_Muscle_Organ_Development | Human | Skin | P5_rep1 | 8.8e-12 |
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IGSF8 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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IGSF8 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for IGSF8 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for IGSF8 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for IGSF8 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
