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Spatial pattern gene: KIFC2 (spascer ID:90990) |
Gene summary for KIFC2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | KIFC2 | Gene ID | 90990 |
| Gene name | kinesin family member C2 |
| Synonyms | - |
| Cytomap | 8q24.3 |
| Type of gene | protein-coding |
| Description | kinesin-like protein KIFC2 |
| Modification date | 20220513 |
| UniProtAcc | Q96AC6 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| KIFC2 | GO:0003777 | microtubule motor activity | 21873635 | Function |
| KIFC2 | GO:0005634 | nucleus | 21873635 | Component |
| KIFC2 | GO:0005815 | microtubule organizing center | 21873635 | Component |
| KIFC2 | GO:0005871 | kinesin complex | 21873635 | Component |
| KIFC2 | GO:0005874 | microtubule | 21873635 | Component |
| KIFC2 | GO:0007018 | microtubule-based movement | 21873635 | Process |
| KIFC2 | GO:0008017 | microtubule binding | 21873635 | Function |
| KIFC2 | GO:0016887 | ATP hydrolysis activity | 21873635 | Function |
| KIFC2 | GO:0072686 | mitotic spindle | 21873635 | Component |
| KIFC2 | GO:0090307 | mitotic spindle assembly | 21873635 | Process |
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Spatial pattern events for KIFC2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| KIFC2 | Human | Brain | rep_9 | 33558695 | 1.82e-06 |
| KIFC2 | Human | Bladder | rep_1 | 34385456 | 2.69e-09 |
| KIFC2 | Human | Bladder | rep_2 | 34385456 | 5.85e-09 |
| KIFC2 | Human | Bladder | rep_3 | 34385456 | 1.87e-12 |
| KIFC2 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| KIFC2 | Human | Intestine | rep_colon4 | 34417225 | 2.06e-15 |
| KIFC2 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| KIFC2 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| KIFC2 | Human | Intestine | A1 | 33406409 | 6.31e-15 |
| KIFC2 | Human | Intestine | A2 | 33406409 | 6.39e-08 |
| KIFC2 | Human | Intestine | A4 | 33406409 | 9.63e-15 |
| KIFC2 | Human | Uterus | rep_3 | 34857954 | 7.84e-08 |
| KIFC2 | Human | Breast | A5 | 34650042 | 7.25e-14 |
| KIFC2 | Human | Breast | E1 | 34650042 | 2.94e-06 |
| KIFC2 | Human | Breast | 1160920F | 34493872 | 1.48e-15 |
| KIFC2 | Human | Breast | CID4535 | 34493872 | 2.08e-14 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Brain_rep_9_H&E  |  |
Bladder_rep_1_H&E  |  |
Bladder_rep_2_H&E  |  |
Bladder_rep_3_H&E  |  |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A1_H&E  |  |
Intestine_A2_H&E  |  |
Intestine_A4_H&E  |  |
Uterus_rep_3_H&E  |  |
Breast_A5_H&E  |  |
Breast_E1_H&E  |  |
Breast_1160920F_H&E  |  |
Breast_CID4535_H&E  |  |
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Spatial pattern pathway has KIFC2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| KIFC2 | GOBP_Cell_Cycle | Human | Intestine | A3 | 2.7e-11 |
| KIFC2 | GOBP_Cell_Cycle_Process | Human | Intestine | A3 | 2.7e-14 |
| KIFC2 | GOBP_Microtubule_Based_Process | Human | Intestine | A3 | 3.4e-11 |
| KIFC2 | GOBP_Microtubule_Cytoskeleton_Organization | Human | Intestine | A3 | 4.8e-11 |
| KIFC2 | GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis | Human | Intestine | A3 | 1.7e-14 |
| KIFC2 | GOBP_Mitotic_Cell_Cycle | Human | Intestine | A3 | 1.8e-12 |
| KIFC2 | GOBP_Mitotic_Nuclear_Division | Human | Intestine | A3 | 5.1e-12 |
| KIFC2 | GOBP_Mitotic_Spindle_Assembly | Human | Intestine | A3 | 3.0e-11 |
| KIFC2 | GOBP_Mitotic_Spindle_Organization | Human | Intestine | A3 | 1.2e-15 |
| KIFC2 | GOBP_Organelle_Fission | Human | Intestine | A3 | 3.4e-16 |
| KIFC2 | GOBP_Spindle_Assembly | Human | Intestine | A3 | 6.2e-09 |
| KIFC2 | GOBP_Spindle_Organization | Human | Intestine | A3 | 4.4e-08 |
| KIFC2 | GOBP_Microtubule_Based_Movement | Human | Intestine | A8 | 2.9e-10 |
| KIFC2 | GOBP_Organelle_Fission | Human | Pancreas | PDAC-B-st1 | 3.9e-05 |
| KIFC2 | GOBP_Spindle_Organization | Human | Pancreas | PDAC-B-st1 | 3.4e-05 |
| KIFC2 | GOBP_Mitotic_Nuclear_Division | Human | Uterus | rep_26 | 2.4e-07 |
| KIFC2 | GOBP_Organelle_Fission | Human | Uterus | rep_26 | 6.0e-11 |
| KIFC2 | GOBP_Spindle_Assembly | Human | Uterus | rep_26 | 8.1e-08 |
| KIFC2 | GOBP_Spindle_Organization | Human | Uterus | rep_26 | 3.2e-06 |
| KIFC2 | GOBP_Cytoskeleton_Organization | Human | Breast | rep_1 | 1.3e-22 |
| KIFC2 | GOBP_Cell_Cycle | Human | Breast | rep_6 | 3.4e-09 |
| KIFC2 | GOBP_Cell_Cycle_Process | Human | Breast | rep_6 | 6.7e-09 |
| KIFC2 | GOBP_Microtubule_Based_Movement | Human | Breast | rep_6 | 8.5e-09 |
| KIFC2 | GOBP_Microtubule_Based_Process | Human | Breast | rep_6 | 1.8e-04 |
| KIFC2 | GOBP_Microtubule_Cytoskeleton_Organization | Human | Breast | rep_6 | 1.9e-04 |
| KIFC2 | GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_Mitosis | Human | Breast | rep_6 | 1.6e-04 |
| KIFC2 | GOBP_Mitotic_Cell_Cycle | Human | Breast | rep_6 | 3.2e-09 |
| KIFC2 | GOBP_Mitotic_Nuclear_Division | Human | Breast | rep_6 | 2.5e-08 |
| KIFC2 | GOBP_Mitotic_Spindle_Assembly | Human | Breast | rep_6 | 2.4e-08 |
| KIFC2 | GOBP_Mitotic_Spindle_Organization | Human | Breast | rep_6 | 3.4e-05 |
| KIFC2 | GOBP_Organelle_Assembly | Human | Breast | rep_6 | 2.3e-07 |
| KIFC2 | GOBP_Organelle_Fission | Human | Breast | rep_6 | 3.0e-05 |
| KIFC2 | GOBP_Spindle_Assembly | Human | Breast | rep_6 | 2.6e-07 |
| KIFC2 | GOBP_Spindle_Organization | Human | Breast | rep_6 | 2.9e-05 |
| KIFC2 | GOBP_Microtubule_Based_Movement | Human | Skin | P5_rep1 | 2.1e-08 |
| KIFC2 | GOBP_Mitotic_Spindle_Assembly | Human | Skin | P5_rep1 | 5.0e-09 |
| KIFC2 | GOBP_Organelle_Fission | Human | Skin | P5_rep3 | 1.0e-09 |
| KIFC2 | GOBP_Cytoskeleton_Organization | Human | Skin | P9_rep3 | 3.1e-12 |
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KIFC2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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KIFC2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for KIFC2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for KIFC2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for KIFC2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
