Home

Download & Upload

Statistics

Landscape

Help

Contact

	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: ESAM (spascer ID:90952)

Gene summary for ESAM

Gene summary

Gene information
	Species	Human
	Gene symbol	ESAM
	Gene ID	90952
	Gene name	endothelial cell adhesion molecule
	Synonyms	W117m
	Cytomap	11q24.2
	Type of gene	protein-coding
	Description	endothelial cell-selective adhesion molecule2310008D05RikHUEL (C4orf1)-interacting proteinLP4791 protein
	Modification date	20220513
	UniProtAcc	Q96AP7

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
ESAM	GO:0005886	plasma membrane	21873635	Component
ESAM	GO:0005912	adherens junction	21873635	Component
ESAM	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	21873635	Process
ESAM	GO:0098632	cell-cell adhesion mediator activity	21873635	Function

Top

Spatial pattern events for ESAM

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
ESAM	Human	Intestine	rep_colon2	34417225	8.12e-16
ESAM	Human	Intestine	rep_colon3	34417225	1.01e-15
ESAM	Human	Liver	rep_liver1	34417225	1.08e-15
ESAM	Human	Uterus	rep_2	34857954	2.55e-15
ESAM	Human	Uterus	rep_3	34857954	1.66e-15
ESAM	Human	Uterus	rep_4	34857954	6.46e-15
ESAM	Human	Breast	CID4465	34493872	4.85e-15
ESAM	Human	Lung	rep_1	35355018	7.55e-15
ESAM	Human	Lung	rep_2	35355018	1.79e-08

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Uterus_rep_4_H&E
Breast_CID4465_H&E
Lung_rep_1_H&E
Lung_rep_2_H&E

Top

Spatial pattern pathway has ESAM envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
ESAM	GOBP_Cell_Migration	Human	Brain	rep_1	3.1e-68
ESAM	GOBP_Locomotion	Human	Brain	rep_1	3.1e-68
ESAM	GOBP_Cell_Migration	Human	Liver	rep_1	1.9e-71
ESAM	GOBP_Locomotion	Human	Liver	rep_1	1.9e-71
ESAM	GOBP_Cell_Migration	Human	Intestine	rep_liver2	1.0e-64
ESAM	GOBP_Locomotion	Human	Intestine	rep_liver2	1.0e-64
ESAM	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
ESAM	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
ESAM	GOBP_Cell_Cell_Junction_Assembly	Human	Intestine	A3	7.8e-08
ESAM	GOBP_Cell_Junction_Assembly	Human	Intestine	A3	6.2e-12
ESAM	GOBP_Cell_Junction_Organization	Human	Intestine	A3	1.1e-08
ESAM	GOBP_Cell_Migration	Human	Intestine	A3	1.6e-10
ESAM	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
ESAM	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
ESAM	GOBP_Leukocyte_Migration	Human	Intestine	A3	1.5e-08
ESAM	GOBP_Locomotion	Human	Intestine	A3	1.9e-08
ESAM	GOBP_Multicellular_Organismal_Homeostasis	Human	Intestine	A3	8.8e-08
ESAM	GOBP_Protein_Polymerization	Human	Intestine	A3	2.3e-10
ESAM	GOBP_Regulation_Of_Actin_Filament_Organization	Human	Intestine	A3	2.2e-08
ESAM	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Intestine	A3	8.8e-12
ESAM	GOBP_Regulation_Of_Cellular_Component_Size	Human	Intestine	A3	3.0e-07
ESAM	GOBP_Regulation_Of_Cytoskeleton_Organization	Human	Intestine	A3	6.4e-13
ESAM	GOBP_Regulation_Of_Organelle_Organization	Human	Intestine	A3	1.1e-11
ESAM	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Intestine	A3	7.4e-11
ESAM	GOBP_Regulation_Of_Protein_Polymerization	Human	Intestine	A3	2.5e-10
ESAM	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Human	Intestine	A3	9.3e-07
ESAM	GOBP_Apical_Junction_Assembly	Human	Intestine	A8	2.6e-24
ESAM	GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Intestine	A8	1.2e-11
ESAM	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Intestine	A8	1.2e-14
ESAM	GOBP_Regulation_Of_Anatomical_Structure_Size	Human	Intestine	A8	3.3e-07
ESAM	GOBP_Anatomical_Structure_Homeostasis	Human	Uterus	rep_1	8.8e-07
ESAM	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Uterus	rep_1	2.1e-06
ESAM	GOBP_Multicellular_Organismal_Homeostasis	Human	Uterus	rep_1	2.0e-06
ESAM	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Human	Uterus	rep_1	6.7e-07
ESAM	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
ESAM	GOBP_Regulation_Of_Protein_Containing_Complex_Assembly	Human	Uterus	rep_26	9.2e-07
ESAM	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
ESAM	GOBP_Leukocyte_Migration	Human	Uterus	rep_29	1.5e-07
ESAM	GOBP_Actin_Cytoskeleton_Reorganization	Human	Breast	rep_1	7.6e-89
ESAM	GOBP_Actin_Filament_Based_Process	Human	Breast	rep_1	1.8e-86
ESAM	GOBP_Actin_Filament_Organization	Human	Breast	rep_1	4.0e-75
ESAM	GOBP_Actin_Polymerization_Or_Depolymerization	Human	Breast	rep_1	6.2e-53
ESAM	GOBP_Apical_Junction_Assembly	Human	Breast	rep_1	5.6e-41
ESAM	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
ESAM	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
ESAM	GOBP_Cell_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Breast	rep_1	3.2e-141
ESAM	GOBP_Cell_Cell_Junction_Assembly	Human	Breast	rep_1	9.9e-144
ESAM	GOBP_Cell_Cell_Junction_Organization	Human	Breast	rep_1	8.1e-146
ESAM	GOBP_Cell_Junction_Assembly	Human	Breast	rep_1	4.4e-63
ESAM	GOBP_Cell_Junction_Organization	Human	Breast	rep_1	3.0e-10
ESAM	GOBP_Cell_Migration	Human	Breast	rep_1	1.5e-45
ESAM	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
ESAM	GOBP_Cytoskeleton_Organization	Human	Breast	rep_1	1.3e-22
ESAM	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
ESAM	GOBP_Homophilic_Cell_Adhesion_Via_Plasma_Membrane_Adhesion_Molecules	Human	Breast	rep_1	1.2e-106
ESAM	GOBP_Locomotion	Human	Breast	rep_1	4.5e-54
ESAM	GOBP_Maintenance_Of_Blood_Brain_Barrier	Human	Breast	rep_1	1.1e-285
ESAM	GOBP_Multicellular_Organismal_Homeostasis	Human	Breast	rep_1	1.5e-16
ESAM	GOBP_Protein_Polymerization	Human	Breast	rep_1	6.4e-28
ESAM	GOBP_Regulation_Of_Actin_Cytoskeleton_Reorganization	Human	Breast	rep_1	4.3e-13
ESAM	GOBP_Regulation_Of_Actin_Filament_Based_Process	Human	Breast	rep_1	8.5e-105
ESAM	GOBP_Regulation_Of_Actin_Filament_Length	Human	Breast	rep_1	1.2e-62
ESAM	GOBP_Regulation_Of_Actin_Filament_Organization	Human	Breast	rep_1	3.2e-110
ESAM	GOBP_Regulation_Of_Anatomical_Structure_Size	Human	Breast	rep_1	1.1e-84
ESAM	GOBP_Regulation_Of_Cellular_Component_Biogenesis	Human	Breast	rep_1	4.6e-05
ESAM	GOBP_Regulation_Of_Cellular_Component_Size	Human	Breast	rep_1	8.6e-78
ESAM	GOBP_Regulation_Of_Cytoskeleton_Organization	Human	Breast	rep_1	7.8e-76
ESAM	GOBP_Regulation_Of_Organelle_Organization	Human	Breast	rep_1	8.7e-11
ESAM	GOBP_Regulation_Of_Protein_Polymerization	Human	Breast	rep_1	3.1e-31
ESAM	GOBP_Regulation_Of_Supramolecular_Fiber_Organization	Human	Breast	rep_1	5.0e-50
ESAM	GOBP_Supramolecular_Fiber_Organization	Human	Breast	rep_1	2.8e-72
ESAM	GOBP_Leukocyte_Migration	Human	Breast	rep_5	6.0e-14
ESAM	GOBP_Cell_Cell_Junction_Organization	Human	Skin	P2_rep1	3.4e-11
ESAM	GOBP_Apical_Junction_Assembly	Human	Skin	P5_rep3	9.9e-09
ESAM	GOBP_Cytoskeleton_Organization	Human	Skin	P9_rep3	3.1e-12
ESAM	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
ESAM	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07

Top

ESAM function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

Top

ESAM function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

Top

Transcription factor for ESAM envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

Top

Related Drugs for ESAM

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for ESAM

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
ESAM	C0036341	Schizophrenia	1	CTD_human