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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: NOL3 (spascer ID:8996)

Gene summary for NOL3

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

NOL3

Gene ID

8996

Gene namenucleolar protein 3
SynonymsARC|FCM|MYOCL1|MYP|NOP|NOP30
Cytomap16q22.1
Type of geneprotein-coding
Descriptionnucleolar protein 3muscle-enriched cytoplasmic proteinnucleolar protein 3 (apoptosis repressor with CARD domain)nucleolar protein of 30 kDa
Modification date20220513
UniProtAcc

O60936


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
NOL3

GO:0005123

death receptor binding

21873635

Function
NOL3

GO:0005739

mitochondrion

21873635

Component
NOL3

GO:0035877

death effector domain binding

21873635

Function
NOL3

GO:0043027

cysteine-type endopeptidase inhibitor activity involved in apoptotic process

21873635

Function
NOL3

GO:0089720

caspase binding

21873635

Function
NOL3

GO:0090201

negative regulation of release of cytochrome c from mitochondria

21873635

Process
NOL3

GO:1990001

inhibition of cysteine-type endopeptidase activity involved in apoptotic process

21873635

Process
NOL3

GO:2001237

negative regulation of extrinsic apoptotic signaling pathway

21873635

Process
NOL3

GO:2001243

negative regulation of intrinsic apoptotic signaling pathway

21873635

Process

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Spatial pattern events for NOL3

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
NOL3HumanIntestinerep_colon1 344172253.58e-06
NOL3HumanIntestinerep_colon4 344172251.72e-08
NOL3HumanLiverrep_liver1 344172256.52e-08
NOL3HumanLiverrep_liver2 344172256.98e-16
NOL3HumanUterusrep_2 348579541.09e-07
NOL3HumanUterusrep_3 348579543.04e-11
NOL3HumanBreast1142243F 344938726.52e-06
NOL3HumanBreast1160920F 344938722.68e-15

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Uterus_rep_2_H&E
boxplot

boxplot
Uterus_rep_3_H&E
boxplot

boxplot
Breast_1142243F_H&E
boxplot

boxplot
Breast_1160920F_H&E
boxplot

boxplot


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Spatial pattern pathway has NOL3 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
NOL3GOBP_Maintenance_Of_LocationHumanBrainrep_1 2.8e-23
NOL3GOBP_Negative_Regulation_Of_Molecular_FunctionHumanBrainrep_1 7.4e-34
NOL3GOBP_Negative_Regulation_Of_Protein_Metabolic_ProcessHumanBrainrep_1 7.4e-34
NOL3GOBP_Negative_Regulation_Of_ProteolysisHumanBrainrep_1 2.8e-23
NOL3GOBP_Protein_MaturationHumanBrainrep_11.3e-161
NOL3GOBP_Protein_ProcessingHumanBrainrep_11.3e-161
NOL3GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanBrainrep_1 1.2e-64
NOL3GOBP_Regulation_Of_ProteolysisHumanBrainrep_1 4.4e-07
NOL3GOBP_Regulation_Of_Response_To_StressHumanBrainrep_1 4.6e-05
NOL3GOBP_Response_To_WoundingHumanBrainrep_16.9e-125
NOL3GOBP_Transmembrane_TransportHumanBrainrep_1 2.8e-23
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanBrainrep_2 2.1e-15
NOL3GOBP_ProteolysisHumanBrainrep_4 1.6e-22
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanBrainrep_4 4.1e-17
NOL3GOBP_Negative_Regulation_Of_Muscle_AdaptationHumanBladderrep_2 4.7e-10
NOL3GOBP_Negative_Regulation_Of_Protein_MaturationHumanBladderrep_2 2.4e-21
NOL3GOBP_Response_To_Stimulus_Involved_In_Regulation_Of_Muscle_AdaptationHumanBladderrep_2 2.7e-04
NOL3GOBP_Necrotic_Cell_DeathHumanBladderrep_4 8.2e-15
NOL3GOBP_Regulation_Of_Necrotic_Cell_DeathHumanBladderrep_4 6.8e-16
NOL3GOBP_Maintenance_Of_LocationHumanLiverrep_1 1.0e-70
NOL3GOBP_Negative_Regulation_Of_Molecular_FunctionHumanLiverrep_1 1.5e-73
NOL3GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanLiverrep_1 2.8e-53
NOL3GOBP_Negative_Regulation_Of_Protein_Metabolic_ProcessHumanLiverrep_1 1.0e-70
NOL3GOBP_Negative_Regulation_Of_ProteolysisHumanLiverrep_1 1.0e-70
NOL3GOBP_Negative_Regulation_Of_Response_To_StimulusHumanLiverrep_1 2.8e-53
NOL3GOBP_Protein_MaturationHumanLiverrep_1 4.6e-81
NOL3GOBP_Protein_ProcessingHumanLiverrep_1 6.7e-84
NOL3GOBP_ProteolysisHumanLiverrep_1 4.2e-73
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanLiverrep_1 6.0e-76
NOL3GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanLiverrep_1 6.9e-47
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanLiverrep_1 6.0e-76
NOL3GOBP_Regulation_Of_ProteolysisHumanLiverrep_1 1.1e-67
NOL3GOBP_Regulation_Of_Response_To_StressHumanLiverrep_1 5.3e-67
NOL3GOBP_Response_To_WoundingHumanLiverrep_1 3.1e-62
NOL3GOBP_Transmembrane_TransportHumanLiverrep_1 1.0e-70
NOL3GOBP_Protein_MaturationHumanIntestinerep_colon2 7.9e-42
NOL3GOBP_Protein_ProcessingHumanIntestinerep_colon2 1.2e-19
NOL3GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanIntestinerep_colon2 2.4e-25
NOL3GOBP_Response_To_WoundingHumanIntestinerep_colon2 3.9e-21
NOL3GOBP_ProteolysisHumanIntestinerep_colon4 2.4e-90
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanIntestinerep_colon4 3.7e-11
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanIntestinerep_colon4 1.9e-09
NOL3GOBP_Regulation_Of_ProteolysisHumanIntestinerep_colon4 1.2e-51
NOL3GOBP_Regulation_Of_Response_To_StressHumanIntestinerep_colon4 2.2e-52
NOL3GOBP_Apoptotic_Mitochondrial_ChangesHumanIntestineA3 1.6e-16
NOL3GOBP_Apoptotic_Signaling_PathwayHumanIntestineA3 7.0e-12
NOL3GOBP_Cation_Transmembrane_TransportHumanIntestineA3 3.4e-12
NOL3GOBP_Cation_TransportHumanIntestineA3 1.3e-09
NOL3GOBP_Cellular_Response_To_Chemical_StressHumanIntestineA3 1.1e-11
NOL3GOBP_Cellular_Response_To_Oxygen_LevelsHumanIntestineA3 2.0e-11
NOL3GOBP_Cytokine_Mediated_Signaling_PathwayHumanIntestineA3 2.6e-09
NOL3GOBP_Extrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 3.4e-16
NOL3GOBP_Homeostatic_ProcessHumanIntestineA3 8.7e-10
NOL3GOBP_Inorganic_Ion_Transmembrane_TransportHumanIntestineA3 1.0e-12
NOL3GOBP_Intrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 2.5e-16
NOL3GOBP_Maintenance_Of_LocationHumanIntestineA3 7.1e-07
NOL3GOBP_Maintenance_Of_Location_In_CellHumanIntestineA3 6.1e-08
NOL3GOBP_Membrane_OrganizationHumanIntestineA3 2.7e-18
NOL3GOBP_Mitochondrial_Membrane_OrganizationHumanIntestineA3 1.0e-17
NOL3GOBP_Mitochondrial_TransportHumanIntestineA3 9.8e-16
NOL3GOBP_Mitochondrion_OrganizationHumanIntestineA3 2.3e-19
NOL3GOBP_Mrna_Metabolic_ProcessHumanIntestineA3 7.7e-20
NOL3GOBP_Mrna_ProcessingHumanIntestineA3 4.9e-17
NOL3GOBP_Mrna_Splice_Site_SelectionHumanIntestineA3 6.7e-13
NOL3GOBP_Muscle_AdaptationHumanIntestineA3 1.0e-08
NOL3GOBP_Muscle_AtrophyHumanIntestineA3 2.2e-07
NOL3GOBP_Muscle_Cell_Apoptotic_ProcessHumanIntestineA3 9.9e-09
NOL3GOBP_Negative_Regulation_Of_Apoptotic_Signaling_PathwayHumanIntestineA3 5.6e-14
NOL3GOBP_Negative_Regulation_Of_Catalytic_ActivityHumanIntestineA3 3.0e-12
NOL3GOBP_Negative_Regulation_Of_Cell_DeathHumanIntestineA3 5.8e-14
NOL3GOBP_Negative_Regulation_Of_Cellular_Component_OrganizationHumanIntestineA3 9.1e-10
NOL3GOBP_Negative_Regulation_Of_Extrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 3.3e-13
NOL3GOBP_Negative_Regulation_Of_Gene_ExpressionHumanIntestineA3 2.8e-18
NOL3GOBP_Negative_Regulation_Of_Hypoxia_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 1.9e-07
NOL3GOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionHumanIntestineA3 2.6e-18
NOL3GOBP_Negative_Regulation_Of_Intrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 1.0e-10
NOL3GOBP_Negative_Regulation_Of_Mitochondrion_OrganizationHumanIntestineA3 4.8e-24
NOL3GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanIntestineA3 6.2e-10
NOL3GOBP_Negative_Regulation_Of_Muscle_Cell_Apoptotic_ProcessHumanIntestineA3 2.2e-13
NOL3GOBP_Negative_Regulation_Of_Organelle_OrganizationHumanIntestineA3 3.5e-11
NOL3GOBP_Negative_Regulation_Of_Protein_Metabolic_ProcessHumanIntestineA3 7.8e-11
NOL3GOBP_Negative_Regulation_Of_Response_To_Cytokine_StimulusHumanIntestineA3 2.2e-07
NOL3GOBP_Negative_Regulation_Of_Response_To_StimulusHumanIntestineA3 6.0e-11
NOL3GOBP_Negative_Regulation_Of_SignalingHumanIntestineA3 4.9e-15
NOL3GOBP_Negative_Regulation_Of_Striated_Muscle_Cell_Apoptotic_ProcessHumanIntestineA3 1.3e-07
NOL3GOBP_Nik_Nf_Kappab_SignalingHumanIntestineA3 2.0e-08
NOL3GOBP_ProteolysisHumanIntestineA3 7.3e-12
NOL3GOBP_Regulation_Of_Apoptotic_Signaling_PathwayHumanIntestineA3 1.3e-15
NOL3GOBP_Regulation_Of_Cell_DeathHumanIntestineA3 7.1e-10
NOL3GOBP_Regulation_Of_Cellular_Response_To_HypoxiaHumanIntestineA3 4.1e-15
NOL3GOBP_Regulation_Of_Cellular_Response_To_StressHumanIntestineA3 7.7e-17
NOL3GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_ActivityHumanIntestineA3 2.9e-10
NOL3GOBP_Regulation_Of_Cytosolic_Calcium_Ion_ConcentrationHumanIntestineA3 1.2e-08
NOL3GOBP_Regulation_Of_Extrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 9.3e-12
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanIntestineA3 7.3e-16
NOL3GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanIntestineA3 7.5e-12
NOL3GOBP_Regulation_Of_Intrinsic_Apoptotic_Signaling_PathwayHumanIntestineA3 1.3e-16
NOL3GOBP_Regulation_Of_Membrane_PermeabilityHumanIntestineA3 6.7e-12
NOL3GOBP_Regulation_Of_Mitochondrial_Membrane_PermeabilityHumanIntestineA3 2.1e-12
NOL3GOBP_Regulation_Of_Mitochondrion_OrganizationHumanIntestineA3 1.6e-17
NOL3GOBP_Regulation_Of_Muscle_AdaptationHumanIntestineA3 1.5e-07
NOL3GOBP_Regulation_Of_Necrotic_Cell_DeathHumanIntestineA3 2.9e-07
NOL3GOBP_Regulation_Of_Nik_Nf_Kappab_SignalingHumanIntestineA3 2.5e-08
NOL3GOBP_Regulation_Of_Organelle_OrganizationHumanIntestineA3 1.1e-11
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanIntestineA3 9.8e-13
NOL3GOBP_Regulation_Of_ProteolysisHumanIntestineA3 9.5e-13
NOL3GOBP_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanIntestineA3 6.1e-09
NOL3GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanIntestineA3 7.7e-20
NOL3GOBP_Regulation_Of_Response_To_StressHumanIntestineA3 1.1e-10
NOL3GOBP_Release_Of_Cytochrome_C_From_MitochondriaHumanIntestineA3 2.6e-09
NOL3GOBP_Response_To_Abiotic_StimulusHumanIntestineA3 5.3e-18
NOL3GOBP_Response_To_Oxidative_StressHumanIntestineA3 5.4e-18
NOL3GOBP_Response_To_Oxygen_LevelsHumanIntestineA3 7.3e-15
NOL3GOBP_Response_To_Tumor_Necrosis_FactorHumanIntestineA3 2.5e-09
NOL3GOBP_Ribonucleoprotein_Complex_Subunit_OrganizationHumanIntestineA3 1.6e-07
NOL3GOBP_Rna_ProcessingHumanIntestineA3 3.9e-09
NOL3GOBP_Rna_SplicingHumanIntestineA3 3.3e-19
NOL3GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanIntestineA3 2.2e-12
NOL3GOBP_Spliceosomal_Complex_AssemblyHumanIntestineA3 8.7e-10
NOL3GOBP_Striated_Muscle_Cell_Apoptotic_ProcessHumanIntestineA3 1.3e-08
NOL3GOBP_Tissue_RemodelingHumanIntestineA3 1.3e-11
NOL3GOBP_Transmembrane_TransportHumanIntestineA3 1.4e-10
NOL3GOBP_Blood_Vessel_RemodelingHumanIntestineA8 3.7e-07
NOL3GOBP_Calcium_Ion_Transmembrane_TransportHumanIntestineA8 5.3e-17
NOL3GOBP_Calcium_Ion_TransportHumanIntestineA8 7.4e-14
NOL3GOBP_Calcium_Ion_Transport_Into_CytosolHumanIntestineA8 1.2e-16
NOL3GOBP_Cellular_HomeostasisHumanIntestineA8 2.1e-11
NOL3GOBP_Cellular_Ion_HomeostasisHumanIntestineA8 4.3e-12
NOL3GOBP_Chemical_HomeostasisHumanIntestineA8 1.3e-12
NOL3GOBP_Cytosolic_Calcium_Ion_TransportHumanIntestineA8 4.8e-16
NOL3GOBP_Divalent_Inorganic_Cation_HomeostasisHumanIntestineA8 1.0e-12
NOL3GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_HypoxiaHumanIntestineA8 2.7e-15
NOL3GOBP_Ion_HomeostasisHumanIntestineA8 6.1e-15
NOL3GOBP_Metal_Ion_HomeostasisHumanIntestineA8 2.2e-10
NOL3GOBP_Metal_Ion_TransportHumanIntestineA8 4.1e-10
NOL3GOBP_Necrotic_Cell_DeathHumanIntestineA8 9.0e-13
NOL3GOBP_Negative_Regulation_Of_Cellular_Response_To_HypoxiaHumanIntestineA8 1.3e-11
NOL3GOBP_Negative_Regulation_Of_Cysteine_Type_Endopeptidase_ActivityHumanIntestineA8 7.6e-13
NOL3GOBP_Negative_Regulation_Of_Hydrolase_ActivityHumanIntestineA8 2.1e-14
NOL3GOBP_Negative_Regulation_Of_Molecular_FunctionHumanIntestineA8 4.6e-12
NOL3GOBP_Negative_Regulation_Of_Necrotic_Cell_DeathHumanIntestineA8 5.1e-12
NOL3GOBP_Negative_Regulation_Of_Peptidase_ActivityHumanIntestineA8 1.7e-19
NOL3GOBP_Negative_Regulation_Of_ProteolysisHumanIntestineA8 8.9e-12
NOL3GOBP_Negative_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanIntestineA8 4.6e-16
NOL3GOBP_Protein_MaturationHumanIntestineA8 1.1e-12
NOL3GOBP_Protein_ProcessingHumanIntestineA8 4.1e-18
NOL3GOBP_Regulation_Of_Muscle_System_ProcessHumanIntestineA8 6.9e-07
NOL3GOBP_Regulation_Of_Protein_MaturationHumanIntestineA8 1.4e-18
NOL3GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanIntestineA8 1.1e-08
NOL3GOBP_Release_Of_Sequestered_Calcium_Ion_Into_Cytosol_By_Endoplasmic_ReticulumHumanIntestineA8 2.0e-17
NOL3GOBP_Response_To_CytokineHumanIntestineA8 1.6e-08
NOL3GOBP_Response_To_IschemiaHumanIntestineA8 1.5e-30
NOL3GOBP_Response_To_Stimulus_Involved_In_Regulation_Of_Muscle_AdaptationHumanIntestineA8 9.4e-11
NOL3GOBP_Sarcoplasmic_Reticulum_Calcium_Ion_TransportHumanIntestineA8 3.4e-15
NOL3GOBP_Sequestering_Of_Calcium_IonHumanIntestineA8 5.3e-15
NOL3GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanIntestineA8 1.1e-17
NOL3GOBP_Calcium_Ion_Transmembrane_TransportHumanPancreasPDAC-B-st1 9.2e-05
NOL3GOBP_Cytosolic_Calcium_Ion_TransportHumanPancreasPDAC-B-st1 7.5e-06
NOL3GOBP_Mrna_Metabolic_ProcessHumanPancreasPDAC-B-st1 2.6e-05
NOL3GOBP_Muscle_Cell_Apoptotic_ProcessHumanPancreasPDAC-B-st1 8.7e-07
NOL3GOBP_Negative_Regulation_Of_Muscle_Cell_Apoptotic_ProcessHumanPancreasPDAC-B-st1 6.3e-05
NOL3GOBP_Negative_Regulation_Of_Organelle_OrganizationHumanPancreasPDAC-B-st1 6.2e-05
NOL3GOBP_Negative_Regulation_Of_Oxidative_Stress_Induced_Cell_DeathHumanPancreasPDAC-B-st1 4.2e-05
NOL3GOBP_Negative_Regulation_Of_SignalingHumanPancreasPDAC-B-st1 1.7e-05
NOL3GOBP_Protein_Complex_OligomerizationHumanPancreasPDAC-B-st1 8.7e-05
NOL3GOBP_Regulation_Of_Oxidative_Stress_Induced_Cell_DeathHumanPancreasPDAC-B-st1 9.8e-05
NOL3GOBP_Regulation_Of_Response_To_Oxidative_StressHumanPancreasPDAC-B-st1 9.8e-05
NOL3GOBP_Rna_SplicingHumanPancreasPDAC-B-st1 1.9e-05
NOL3GOBP_Sequestering_Of_Calcium_IonHumanPancreasPDAC-B-st1 4.7e-05
NOL3GOBP_Striated_Muscle_Cell_Apoptotic_ProcessHumanPancreasPDAC-B-st1 1.3e-05
NOL3GOBP_Negative_Regulation_Of_Muscle_AdaptationHumanUterusrep_1 2.7e-09
NOL3GOBP_Striated_Muscle_Cell_Apoptotic_ProcessHumanUterusrep_1 1.9e-07
NOL3GOBP_Negative_Regulation_Of_Mitochondrial_Membrane_PermeabilityHumanUterusrep_4 2.4e-08
NOL3GOBP_Muscle_AtrophyHumanUterusrep_25 1.0e-08
NOL3GOBP_Muscle_Cell_Apoptotic_ProcessHumanUterusrep_25 5.4e-08
NOL3GOBP_Negative_Regulation_Of_Membrane_PermeabilityHumanUterusrep_25 8.2e-06
NOL3GOBP_Negative_Regulation_Of_Muscle_Cell_Apoptotic_ProcessHumanUterusrep_25 6.0e-09
NOL3GOBP_Negative_Regulation_Of_Necrotic_Cell_DeathHumanUterusrep_25 6.2e-09
NOL3GOBP_Negative_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanUterusrep_25 1.7e-11
NOL3GOBP_Negative_Regulation_Of_Striated_Muscle_Cell_Apoptotic_ProcessHumanUterusrep_25 4.3e-09
NOL3GOBP_Regulation_Of_Muscle_AdaptationHumanUterusrep_25 1.6e-10
NOL3GOBP_Release_Of_Sequestered_Calcium_Ion_Into_Cytosol_By_Endoplasmic_ReticulumHumanUterusrep_25 1.1e-18
NOL3GOBP_Response_To_Stimulus_Involved_In_Regulation_Of_Muscle_AdaptationHumanUterusrep_25 3.8e-18
NOL3GOBP_Sarcoplasmic_Reticulum_Calcium_Ion_TransportHumanUterusrep_25 1.1e-09
NOL3GOBP_Zymogen_InhibitionHumanUterusrep_25 1.7e-17
NOL3GOBP_Calcium_Ion_Transmembrane_TransportHumanUterusrep_26 1.7e-10
NOL3GOBP_Calcium_Ion_TransportHumanUterusrep_26 5.1e-08
NOL3GOBP_Cytokine_Mediated_Signaling_PathwayHumanUterusrep_26 2.0e-10
NOL3GOBP_Extrinsic_Apoptotic_Signaling_PathwayHumanUterusrep_26 1.2e-09
NOL3GOBP_Homeostatic_ProcessHumanUterusrep_26 1.9e-07
NOL3GOBP_Inorganic_Ion_Transmembrane_TransportHumanUterusrep_26 6.1e-08
NOL3GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_HypoxiaHumanUterusrep_26 5.4e-13
NOL3GOBP_Mitochondrial_Membrane_OrganizationHumanUterusrep_26 1.5e-06
NOL3GOBP_Muscle_AdaptationHumanUterusrep_26 2.1e-13
NOL3GOBP_Negative_Regulation_Of_Cellular_Response_To_HypoxiaHumanUterusrep_26 6.7e-12
NOL3GOBP_Negative_Regulation_Of_Hypoxia_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanUterusrep_26 1.3e-15
NOL3GOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionHumanUterusrep_26 2.7e-06
NOL3GOBP_Negative_Regulation_Of_Mitochondrion_OrganizationHumanUterusrep_26 6.7e-08
NOL3GOBP_Negative_Regulation_Of_Oxidative_Stress_Induced_Cell_DeathHumanUterusrep_26 3.1e-07
NOL3GOBP_Negative_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanUterusrep_26 1.4e-08
NOL3GOBP_Nik_Nf_Kappab_SignalingHumanUterusrep_26 1.7e-11
NOL3GOBP_Regulation_Of_Cellular_Response_To_HypoxiaHumanUterusrep_26 4.4e-10
NOL3GOBP_Regulation_Of_Muscle_System_ProcessHumanUterusrep_26 6.9e-08
NOL3GOBP_Regulation_Of_Necrotic_Cell_DeathHumanUterusrep_26 1.5e-08
NOL3GOBP_Regulation_Of_Nik_Nf_Kappab_SignalingHumanUterusrep_26 8.5e-12
NOL3GOBP_Regulation_Of_Protein_MaturationHumanUterusrep_26 4.4e-13
NOL3GOBP_Regulation_Of_ProteolysisHumanUterusrep_26 2.1e-07
NOL3GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanUterusrep_26 2.4e-10
NOL3GOBP_Regulation_Of_System_ProcessHumanUterusrep_26 6.6e-10
NOL3GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanUterusrep_26 1.8e-08
NOL3GOBP_Response_To_IschemiaHumanUterusrep_26 9.9e-09
NOL3GOBP_Response_To_Tumor_Necrosis_FactorHumanUterusrep_26 1.5e-09
NOL3GOBP_Ribonucleoprotein_Complex_Subunit_OrganizationHumanUterusrep_26 4.6e-06
NOL3GOBP_Rna_SplicingHumanUterusrep_26 1.0e-05
NOL3GOBP_Spliceosomal_Complex_AssemblyHumanUterusrep_26 5.6e-09
NOL3GOBP_Release_Of_Cytochrome_C_From_MitochondriaHumanUterusrep_27 1.5e-06
NOL3GOBP_Blood_Vessel_RemodelingHumanUterusrep_29 6.0e-08
NOL3GOBP_Cytosolic_Calcium_Ion_TransportHumanUterusrep_29 3.6e-07
NOL3GOBP_Negative_Regulation_Of_Catalytic_ActivityHumanUterusrep_29 4.3e-12
NOL3GOBP_Negative_Regulation_Of_Hydrolase_ActivityHumanUterusrep_29 2.9e-08
NOL3GOBP_Negative_Regulation_Of_Intrinsic_Apoptotic_Signaling_PathwayHumanUterusrep_29 4.2e-06
NOL3GOBP_Negative_Regulation_Of_Molecular_FunctionHumanUterusrep_29 1.6e-12
NOL3GOBP_Negative_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanUterusrep_29 9.8e-08
NOL3GOBP_Negative_Regulation_Of_Peptidase_ActivityHumanUterusrep_29 2.0e-13
NOL3GOBP_Negative_Regulation_Of_Response_To_StimulusHumanUterusrep_29 1.2e-06
NOL3GOBP_Negative_Regulation_Of_SignalingHumanUterusrep_29 5.3e-06
NOL3GOBP_Regulation_Of_Cytosolic_Calcium_Ion_ConcentrationHumanUterusrep_29 4.5e-07
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanUterusrep_29 6.6e-10
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanUterusrep_29 1.4e-10
NOL3GOBP_Apoptotic_Mitochondrial_ChangesHumanBreastrep_1 9.3e-30
NOL3GOBP_Blood_Vessel_RemodelingHumanBreastrep_1 2.5e-36
NOL3GOBP_Calcium_Ion_Transmembrane_TransportHumanBreastrep_1 9.2e-13
NOL3GOBP_Calcium_Ion_TransportHumanBreastrep_1 5.4e-24
NOL3GOBP_Calcium_Ion_Transport_Into_CytosolHumanBreastrep_1 1.4e-13
NOL3GOBP_Cation_Transmembrane_TransportHumanBreastrep_1 3.6e-30
NOL3GOBP_Cation_TransportHumanBreastrep_1 8.4e-53
NOL3GOBP_Cellular_HomeostasisHumanBreastrep_1 2.8e-10
NOL3GOBP_Cellular_Ion_HomeostasisHumanBreastrep_1 7.6e-24
NOL3GOBP_Chemical_HomeostasisHumanBreastrep_1 4.8e-18
NOL3GOBP_Cytokine_Mediated_Signaling_PathwayHumanBreastrep_11.5e-144
NOL3GOBP_Cytosolic_Calcium_Ion_TransportHumanBreastrep_1 8.8e-12
NOL3GOBP_Divalent_Inorganic_Cation_HomeostasisHumanBreastrep_1 1.2e-25
NOL3GOBP_Homeostatic_ProcessHumanBreastrep_1 9.0e-53
NOL3GOBP_Inorganic_Ion_Transmembrane_TransportHumanBreastrep_1 1.9e-35
NOL3GOBP_Ion_HomeostasisHumanBreastrep_1 1.4e-53
NOL3GOBP_Maintenance_Of_LocationHumanBreastrep_1 3.8e-39
NOL3GOBP_Maintenance_Of_Location_In_CellHumanBreastrep_1 1.4e-24
NOL3GOBP_Metal_Ion_HomeostasisHumanBreastrep_1 6.8e-70
NOL3GOBP_Metal_Ion_TransportHumanBreastrep_1 7.5e-64
NOL3GOBP_Muscle_AdaptationHumanBreastrep_1 9.9e-38
NOL3GOBP_Muscle_AtrophyHumanBreastrep_1 4.3e-44
NOL3GOBP_Muscle_System_ProcessHumanBreastrep_1 5.3e-20
NOL3GOBP_Necrotic_Cell_DeathHumanBreastrep_1 1.3e-71
NOL3GOBP_Negative_Regulation_Of_Cellular_Component_OrganizationHumanBreastrep_1 7.3e-14
NOL3GOBP_Negative_Regulation_Of_Intracellular_Signal_TransductionHumanBreastrep_1 3.6e-04
NOL3GOBP_Negative_Regulation_Of_Molecular_FunctionHumanBreastrep_1 7.1e-11
NOL3GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanBreastrep_1 8.3e-12
NOL3GOBP_Negative_Regulation_Of_Organelle_OrganizationHumanBreastrep_1 2.9e-09
NOL3GOBP_Negative_Regulation_Of_Peptidase_ActivityHumanBreastrep_1 7.8e-05
NOL3GOBP_Negative_Regulation_Of_Protein_MaturationHumanBreastrep_1 2.9e-14
NOL3GOBP_Negative_Regulation_Of_Response_To_Cytokine_StimulusHumanBreastrep_1 2.1e-92
NOL3GOBP_Negative_Regulation_Of_Response_To_StimulusHumanBreastrep_1 2.4e-07
NOL3GOBP_Negative_Regulation_Of_Striated_Muscle_Cell_Apoptotic_ProcessHumanBreastrep_1 1.4e-05
NOL3GOBP_Protein_Complex_OligomerizationHumanBreastrep_1 1.7e-04
NOL3GOBP_Protein_MaturationHumanBreastrep_1 4.1e-23
NOL3GOBP_Protein_ProcessingHumanBreastrep_1 4.4e-37
NOL3GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_ActivityHumanBreastrep_1 3.8e-05
NOL3GOBP_Regulation_Of_Cytosolic_Calcium_Ion_ConcentrationHumanBreastrep_12.9e-140
NOL3GOBP_Regulation_Of_Extrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_1 1.4e-06
NOL3GOBP_Regulation_Of_Muscle_AdaptationHumanBreastrep_1 5.0e-42
NOL3GOBP_Regulation_Of_Muscle_System_ProcessHumanBreastrep_1 5.5e-10
NOL3GOBP_Regulation_Of_Necrotic_Cell_DeathHumanBreastrep_1 3.7e-53
NOL3GOBP_Regulation_Of_Organelle_OrganizationHumanBreastrep_1 8.7e-11
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanBreastrep_1 2.2e-33
NOL3GOBP_Regulation_Of_Protein_MaturationHumanBreastrep_1 3.1e-43
NOL3GOBP_Regulation_Of_ProteolysisHumanBreastrep_1 6.4e-05
NOL3GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanBreastrep_12.1e-159
NOL3GOBP_Regulation_Of_Response_To_StressHumanBreastrep_1 3.4e-19
NOL3GOBP_Regulation_Of_System_ProcessHumanBreastrep_1 1.0e-09
NOL3GOBP_Release_Of_Cytochrome_C_From_MitochondriaHumanBreastrep_1 2.9e-49
NOL3GOBP_Response_To_Abiotic_StimulusHumanBreastrep_1 2.6e-19
NOL3GOBP_Response_To_CytokineHumanBreastrep_1 2.5e-24
NOL3GOBP_Response_To_Oxygen_LevelsHumanBreastrep_1 6.1e-99
NOL3GOBP_Response_To_Stimulus_Involved_In_Regulation_Of_Muscle_AdaptationHumanBreastrep_11.0e-123
NOL3GOBP_Response_To_Tumor_Necrosis_FactorHumanBreastrep_1 1.7e-52
NOL3GOBP_Response_To_WoundingHumanBreastrep_14.7e-165
NOL3GOBP_Striated_Muscle_Cell_Apoptotic_ProcessHumanBreastrep_1 9.9e-13
NOL3GOBP_Tissue_RemodelingHumanBreastrep_1 9.1e-41
NOL3GOBP_Transmembrane_TransportHumanBreastrep_1 3.2e-56
NOL3GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanBreastrep_1 1.8e-64
NOL3GOBP_Zymogen_InhibitionHumanBreastrep_1 4.6e-52
NOL3GOBP_Cellular_Response_To_Oxygen_LevelsHumanBreastrep_5 4.9e-11
NOL3GOBP_Extrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_5 7.1e-11
NOL3GOBP_Intrinsic_Apoptotic_Signaling_Pathway_In_Response_To_HypoxiaHumanBreastrep_5 2.2e-15
NOL3GOBP_Negative_Regulation_Of_Apoptotic_Signaling_PathwayHumanBreastrep_5 2.5e-09
NOL3GOBP_Negative_Regulation_Of_Catalytic_ActivityHumanBreastrep_5 3.6e-05
NOL3GOBP_Negative_Regulation_Of_Cell_DeathHumanBreastrep_5 1.9e-07
NOL3GOBP_Negative_Regulation_Of_Cellular_Response_To_HypoxiaHumanBreastrep_5 1.5e-17
NOL3GOBP_Negative_Regulation_Of_Extrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_5 5.3e-11
NOL3GOBP_Negative_Regulation_Of_Gene_ExpressionHumanBreastrep_5 5.3e-06
NOL3GOBP_Negative_Regulation_Of_Hypoxia_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_5 6.9e-25
NOL3GOBP_Negative_Regulation_Of_Muscle_AdaptationHumanBreastrep_5 3.4e-10
NOL3GOBP_Negative_Regulation_Of_Necrotic_Cell_DeathHumanBreastrep_5 5.4e-08
NOL3GOBP_Negative_Regulation_Of_Protein_Metabolic_ProcessHumanBreastrep_5 4.3e-05
NOL3GOBP_Negative_Regulation_Of_ProteolysisHumanBreastrep_5 2.0e-06
NOL3GOBP_Negative_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanBreastrep_5 1.3e-06
NOL3GOBP_Negative_Regulation_Of_SignalingHumanBreastrep_5 8.6e-14
NOL3GOBP_Nik_Nf_Kappab_SignalingHumanBreastrep_5 1.3e-07
NOL3GOBP_ProteolysisHumanBreastrep_5 1.8e-07
NOL3GOBP_Regulation_Of_Cell_DeathHumanBreastrep_5 9.8e-08
NOL3GOBP_Regulation_Of_Cellular_Response_To_HypoxiaHumanBreastrep_5 6.5e-04
NOL3GOBP_Regulation_Of_Cellular_Response_To_StressHumanBreastrep_5 8.1e-10
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanBreastrep_5 3.2e-13
NOL3GOBP_Regulation_Of_Intracellular_Signal_TransductionHumanBreastrep_5 8.7e-11
NOL3GOBP_Regulation_Of_Nik_Nf_Kappab_SignalingHumanBreastrep_5 2.7e-07
NOL3GOBP_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_5 5.9e-08
NOL3GOBP_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanBreastrep_5 3.2e-09
NOL3GOBP_Response_To_IschemiaHumanBreastrep_5 5.2e-10
NOL3GOBP_Response_To_Oxidative_StressHumanBreastrep_5 1.0e-04
NOL3GOBP_Sequestering_Of_Calcium_IonHumanBreastrep_5 1.4e-07
NOL3GOBP_Apoptotic_Signaling_PathwayHumanBreastrep_6 4.8e-09
NOL3GOBP_Cell_Death_In_Response_To_Oxidative_StressHumanBreastrep_6 1.9e-04
NOL3GOBP_Cellular_Response_To_Chemical_StressHumanBreastrep_6 3.6e-05
NOL3GOBP_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_6 2.7e-08
NOL3GOBP_Mitochondrial_Membrane_OrganizationHumanBreastrep_6 3.7e-05
NOL3GOBP_Mitochondrial_TransportHumanBreastrep_6 6.5e-10
NOL3GOBP_Mitochondrion_OrganizationHumanBreastrep_6 2.0e-05
NOL3GOBP_Mrna_Metabolic_ProcessHumanBreastrep_6 3.0e-08
NOL3GOBP_Mrna_ProcessingHumanBreastrep_6 1.5e-06
NOL3GOBP_Mrna_Splice_Site_SelectionHumanBreastrep_6 7.1e-06
NOL3GOBP_Negative_Regulation_Of_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_6 2.1e-09
NOL3GOBP_Negative_Regulation_Of_Membrane_PermeabilityHumanBreastrep_6 1.1e-08
NOL3GOBP_Negative_Regulation_Of_Mitochondrion_OrganizationHumanBreastrep_6 5.2e-08
NOL3GOBP_Negative_Regulation_Of_Muscle_Cell_Apoptotic_ProcessHumanBreastrep_6 5.0e-04
NOL3GOBP_Negative_Regulation_Of_Oxidative_Stress_Induced_Cell_DeathHumanBreastrep_6 5.7e-10
NOL3GOBP_Negative_Regulation_Of_Oxidative_Stress_Induced_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_6 5.7e-07
NOL3GOBP_Regulation_Of_Apoptotic_Signaling_PathwayHumanBreastrep_6 1.6e-07
NOL3GOBP_Regulation_Of_Intrinsic_Apoptotic_Signaling_PathwayHumanBreastrep_6 3.3e-09
NOL3GOBP_Regulation_Of_Membrane_PermeabilityHumanBreastrep_6 1.8e-09
NOL3GOBP_Regulation_Of_Mitochondrial_Membrane_PermeabilityHumanBreastrep_6 2.3e-08
NOL3GOBP_Regulation_Of_Mitochondrion_OrganizationHumanBreastrep_6 1.3e-06
NOL3GOBP_Regulation_Of_Oxidative_Stress_Induced_Cell_DeathHumanBreastrep_6 1.8e-05
NOL3GOBP_Regulation_Of_Response_To_Oxidative_StressHumanBreastrep_6 8.1e-05
NOL3GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanBreastrep_6 1.0e-05
NOL3GOBP_Release_Of_Sequestered_Calcium_Ion_Into_Cytosol_By_Endoplasmic_ReticulumHumanBreastrep_6 3.6e-07
NOL3GOBP_Ribonucleoprotein_Complex_BiogenesisHumanBreastrep_6 1.3e-07
NOL3GOBP_Ribonucleoprotein_Complex_Subunit_OrganizationHumanBreastrep_6 1.4e-08
NOL3GOBP_Rna_ProcessingHumanBreastrep_6 3.5e-06
NOL3GOBP_Rna_SplicingHumanBreastrep_6 1.1e-09
NOL3GOBP_Rna_Splicing_Via_Transesterification_ReactionsHumanBreastrep_6 5.4e-08
NOL3GOBP_Sarcoplasmic_Reticulum_Calcium_Ion_TransportHumanBreastrep_6 1.9e-06
NOL3GOBP_Spliceosomal_Complex_AssemblyHumanBreastrep_6 2.2e-12
NOL3GOBP_Maintenance_Of_Location_In_CellHumanSkinP2_rep1 9.7e-09
NOL3GOBP_Negative_Regulation_Of_Protein_MaturationHumanSkinP2_rep2 6.1e-15
NOL3GOBP_Sarcoplasmic_Reticulum_Calcium_Ion_TransportHumanSkinP2_rep2 2.2e-08
NOL3GOBP_Zymogen_InhibitionHumanSkinP2_rep2 7.1e-08
NOL3GOBP_Divalent_Inorganic_Cation_HomeostasisHumanSkinP2_rep3 1.3e-08
NOL3GOBP_Mitochondrial_Membrane_OrganizationHumanSkinP5_rep3 2.4e-11
NOL3GOBP_Mrna_Metabolic_ProcessHumanSkinP5_rep3 1.8e-08
NOL3GOBP_Mrna_ProcessingHumanSkinP5_rep3 9.7e-09
NOL3GOBP_Negative_Regulation_Of_Cellular_Response_To_HypoxiaHumanSkinP5_rep3 8.6e-09
NOL3GOBP_Negative_Regulation_Of_Extrinsic_Apoptotic_Signaling_PathwayHumanSkinP5_rep3 1.2e-08
NOL3GOBP_Response_To_IschemiaHumanSkinP9_rep2 2.3e-08
NOL3GOBP_Intrinsic_Apoptotic_Signaling_PathwayHumanSkinP9_rep3 4.3e-09
NOL3GOBP_Calcium_Ion_Transport_Into_CytosolHumanSkinP10_rep1 4.6e-09
NOL3GOBP_Muscle_AtrophyHumanSkinP10_rep1 4.6e-10
NOL3GOBP_Mrna_Splice_Site_SelectionHumanSkinP10_rep2 2.9e-12
NOL3GOBP_Negative_Regulation_Of_Mitochondrial_Membrane_Permeability_Involved_In_Apoptotic_ProcessHumanSkinP10_rep2 1.8e-22
NOL3GOBP_Negative_Regulation_Of_Necrotic_Cell_DeathHumanSkinP10_rep2 2.3e-08
NOL3GOBP_Negative_Regulation_Of_Release_Of_Cytochrome_C_From_MitochondriaHumanSkinP10_rep2 1.2e-10
NOL3GOBP_Regulation_Of_Muscle_AdaptationHumanSkinP10_rep2 1.8e-13
NOL3GOBP_Response_To_Stimulus_Involved_In_Regulation_Of_Muscle_AdaptationHumanSkinP10_rep2 5.3e-18
NOL3GOBP_Sequestering_Of_Calcium_IonHumanSkinP10_rep2 6.1e-08
NOL3GOBP_Blood_Vessel_RemodelingHumanLungrep_1 1.9e-11
NOL3GOBP_Cellular_Response_To_Oxygen_LevelsHumanLungrep_1 2.8e-10
NOL3GOBP_Ion_HomeostasisHumanLungrep_1 6.1e-07
NOL3GOBP_Negative_Regulation_Of_Catalytic_ActivityHumanLungrep_1 1.4e-08
NOL3GOBP_Negative_Regulation_Of_Hydrolase_ActivityHumanLungrep_1 5.7e-10
NOL3GOBP_Negative_Regulation_Of_Peptidase_ActivityHumanLungrep_1 4.6e-10
NOL3GOBP_Negative_Regulation_Of_ProteolysisHumanLungrep_1 5.7e-10
NOL3GOBP_Regulation_Of_Cysteine_Type_Endopeptidase_ActivityHumanLungrep_1 9.0e-08
NOL3GOBP_Regulation_Of_Hydrolase_ActivityHumanLungrep_1 4.1e-07
NOL3GOBP_Regulation_Of_Peptidase_ActivityHumanLungrep_1 4.6e-11
NOL3GOBP_Regulation_Of_ProteolysisHumanLungrep_1 3.2e-08
NOL3GOBP_Cellular_HomeostasisHumanLungrep_2 7.3e-07
NOL3GOBP_Maintenance_Of_LocationHumanLungrep_2 1.1e-08
NOL3GOBP_Maintenance_Of_Location_In_CellHumanLungrep_2 2.8e-08
NOL3GOBP_Metal_Ion_TransportHumanLungrep_2 1.6e-07

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NOL3 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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NOL3 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for NOL3 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for NOL3

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for NOL3

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource
NOL3C3539916MYOCLONUS, FAMILIAL CORTICAL2CTD_human;ORPHANET;UNIPROT
NOL3C0751651Mitochondrial Diseases1CTD_human
NOL3C0949855Electron Transport Chain Deficiencies, Mitochondrial1CTD_human
NOL3C0949856Oxidative Phosphorylation Deficiencies1CTD_human
NOL3C0949857Mitochondrial Respiratory Chain Deficiencies1CTD_human