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Center for Computational Systems Medicine
Soverview

Gene summary

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Spatial pattern genes

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Spatial pattern pathway

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Cell cell interactions using single cell data

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Cell-cell/spot-spot interactions using spatial data

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Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: SAPCD2 (spascer ID:89958)

Gene summary for SAPCD2

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

SAPCD2

Gene ID

89958

Gene namesuppressor APC domain containing 2
SynonymsC9orf140|p42.3
Cytomap9q34.3
Type of geneprotein-coding
Descriptionsuppressor APC domain-containing protein 22010317E24RikTS/MDEPprotein C9orf140tumor specificity and mitosis phase-dependent expression protein
Modification date20220513
UniProtAcc

Q86UD0


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory

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Spatial pattern events for SAPCD2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
SAPCD2HumanIntestinerep_colon1 344172251.95e-15
SAPCD2HumanIntestinerep_colon4 344172251.14e-15
SAPCD2HumanLiverrep_liver1 344172253.57e-15
SAPCD2HumanLiverrep_liver2 344172256.98e-16
SAPCD2HumanUterusrep_1 348579549.89e-12
SAPCD2HumanBreast1142243F 344938722.49e-12
SAPCD2HumanBreastCID4465 344938727.83e-15
SAPCD2HumanBreastCID44971 344938721.76e-15
SAPCD2HumanBreastCID4535 344938721.90e-09

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
boxplot

boxplot
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Uterus_rep_1_H&E
boxplot

boxplot
Breast_1142243F_H&E
boxplot

boxplot
Breast_CID4465_H&E
boxplot

boxplot
Breast_CID44971_H&E
boxplot

boxplot
Breast_CID4535_H&E
boxplot

boxplot


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Spatial pattern pathway has SAPCD2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanBrainrep_1 1.3e-60
SAPCD2GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanBrainrep_4 4.1e-17
SAPCD2GOBP_Regulation_Of_Protein_LocalizationHumanBrainrep_4 1.0e-14
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanLiverrep_1 2.0e-49
SAPCD2GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanLiverrep_1 1.0e-70
SAPCD2GOBP_Regulation_Of_Protein_LocalizationHumanLiverrep_1 2.1e-52
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanIntestinerep_colon2 2.9e-50
SAPCD2GOBP_Regulation_Of_Protein_LocalizationHumanIntestinerep_colon2 1.5e-57
SAPCD2GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanIntestinerep_colon4 9.0e-12
SAPCD2GOBP_Cell_CycleHumanIntestineA3 2.7e-11
SAPCD2GOBP_Cell_Cycle_ProcessHumanIntestineA3 2.7e-14
SAPCD2GOBP_Cell_DivisionHumanIntestineA3 2.7e-10
SAPCD2GOBP_Cellular_Macromolecule_LocalizationHumanIntestineA3 1.7e-09
SAPCD2GOBP_Establishment_Of_Cell_PolarityHumanIntestineA3 1.0e-09
SAPCD2GOBP_Establishment_Of_Organelle_LocalizationHumanIntestineA3 9.7e-13
SAPCD2GOBP_Establishment_Or_Maintenance_Of_Cell_PolarityHumanIntestineA3 8.2e-09
SAPCD2GOBP_Microtubule_Based_ProcessHumanIntestineA3 3.4e-11
SAPCD2GOBP_Microtubule_Cytoskeleton_OrganizationHumanIntestineA3 4.8e-11
SAPCD2GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_MitosisHumanIntestineA3 1.7e-14
SAPCD2GOBP_Mitotic_Cell_CycleHumanIntestineA3 1.8e-12
SAPCD2GOBP_Morphogenesis_Of_An_EpitheliumHumanIntestineA3 1.5e-09
SAPCD2GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_PeripheryHumanIntestineA3 1.4e-08
SAPCD2GOBP_Organelle_LocalizationHumanIntestineA3 5.1e-12
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanIntestineA3 3.5e-07
SAPCD2GOBP_Protein_Localization_To_Cell_PeripheryHumanIntestineA3 4.6e-14
SAPCD2GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanIntestineA3 4.8e-12
SAPCD2GOBP_Regulation_Of_Cellular_LocalizationHumanIntestineA3 4.5e-11
SAPCD2GOBP_Regulation_Of_Protein_LocalizationHumanIntestineA3 7.5e-08
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_PeripheryHumanIntestineA3 2.1e-07
SAPCD2GOBP_Establishment_Of_Mitotic_Spindle_LocalizationHumanIntestineA8 8.1e-08
SAPCD2GOBP_Establishment_Of_Spindle_OrientationHumanIntestineA8 2.5e-12
SAPCD2GOBP_Protein_Localization_To_Cell_CortexHumanIntestineA8 1.8e-18
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_CortexHumanIntestineA8 3.2e-14
SAPCD2GOBP_Spindle_LocalizationHumanIntestineA8 9.9e-10
SAPCD2GOBP_Cell_DivisionHumanPancreasPDAC-B-st1 5.8e-05
SAPCD2GOBP_Establishment_Of_Mitotic_Spindle_LocalizationHumanPancreasPDAC-B-st1 6.5e-05
SAPCD2GOBP_Establishment_Of_Tissue_PolarityHumanPancreasPDAC-B-st1 5.4e-06
SAPCD2GOBP_Protein_Localization_To_Cell_CortexHumanPancreasPDAC-B-st1 6.5e-05
SAPCD2GOBP_Establishment_Of_Spindle_OrientationHumanPancreasPDAC-A-st2 2.6e-08
SAPCD2GOBP_Establishment_Of_Mitotic_Spindle_LocalizationHumanUterusrep_26 2.0e-14
SAPCD2GOBP_Establishment_Of_Spindle_OrientationHumanUterusrep_26 4.2e-12
SAPCD2GOBP_Protein_Localization_To_Cell_CortexHumanUterusrep_26 6.5e-11
SAPCD2GOBP_Regulation_Of_Animal_Organ_MorphogenesisHumanUterusrep_26 5.0e-06
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_CortexHumanUterusrep_26 4.4e-06
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_PeripheryHumanUterusrep_26 3.9e-06
SAPCD2GOBP_Spindle_LocalizationHumanUterusrep_26 2.3e-08
SAPCD2GOBP_Animal_Organ_MorphogenesisHumanBreastrep_1 5.4e-25
SAPCD2GOBP_Cellular_Macromolecule_LocalizationHumanBreastrep_1 3.7e-09
SAPCD2GOBP_Cytoskeleton_OrganizationHumanBreastrep_1 1.3e-22
SAPCD2GOBP_Epithelium_DevelopmentHumanBreastrep_1 2.0e-22
SAPCD2GOBP_Establishment_Of_Cell_PolarityHumanBreastrep_1 3.9e-06
SAPCD2GOBP_Establishment_Of_Organelle_LocalizationHumanBreastrep_1 6.5e-08
SAPCD2GOBP_Establishment_Or_Maintenance_Of_Cell_PolarityHumanBreastrep_1 1.1e-43
SAPCD2GOBP_Morphogenesis_Of_A_Polarized_EpitheliumHumanBreastrep_16.4e-139
SAPCD2GOBP_Morphogenesis_Of_An_EpitheliumHumanBreastrep_1 2.3e-18
SAPCD2GOBP_Organelle_LocalizationHumanBreastrep_1 1.8e-08
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanBreastrep_1 9.2e-11
SAPCD2GOBP_Protein_Localization_To_Cell_PeripheryHumanBreastrep_1 7.2e-19
SAPCD2GOBP_Regulation_Of_Anatomical_Structure_MorphogenesisHumanBreastrep_1 4.6e-22
SAPCD2GOBP_Regulation_Of_Cellular_LocalizationHumanBreastrep_1 5.5e-07
SAPCD2GOBP_Regulation_Of_Protein_LocalizationHumanBreastrep_1 2.8e-21
SAPCD2GOBP_Tissue_MorphogenesisHumanBreastrep_1 1.4e-30
SAPCD2GOBP_Establishment_Of_Tissue_PolarityHumanBreastrep_5 8.3e-16
SAPCD2GOBP_Negative_Regulation_Of_Protein_Localization_To_Cell_PeripheryHumanBreastrep_5 6.3e-15
SAPCD2GOBP_Regulation_Of_Animal_Organ_MorphogenesisHumanBreastrep_5 2.2e-14
SAPCD2GOBP_Cell_CycleHumanBreastrep_6 3.4e-09
SAPCD2GOBP_Cell_Cycle_ProcessHumanBreastrep_6 6.7e-09
SAPCD2GOBP_Cell_DivisionHumanBreastrep_6 8.2e-07
SAPCD2GOBP_Establishment_Of_Mitotic_Spindle_LocalizationHumanBreastrep_6 5.3e-06
SAPCD2GOBP_Establishment_Of_Spindle_OrientationHumanBreastrep_6 9.5e-10
SAPCD2GOBP_Microtubule_Based_ProcessHumanBreastrep_6 1.8e-04
SAPCD2GOBP_Microtubule_Cytoskeleton_OrganizationHumanBreastrep_6 1.9e-04
SAPCD2GOBP_Microtubule_Cytoskeleton_Organization_Involved_In_MitosisHumanBreastrep_6 1.6e-04
SAPCD2GOBP_Mitotic_Cell_CycleHumanBreastrep_6 3.2e-09
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_CortexHumanBreastrep_6 9.4e-04
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_PeripheryHumanBreastrep_6 1.2e-06
SAPCD2GOBP_Spindle_LocalizationHumanBreastrep_6 1.1e-05
SAPCD2GOBP_Tissue_MorphogenesisHumanSkinP2_rep1 2.9e-08
SAPCD2GOBP_Regulation_Of_Animal_Organ_MorphogenesisHumanSkinP2_rep2 1.8e-08
SAPCD2GOBP_Organelle_LocalizationHumanSkinP5_rep1 2.1e-13
SAPCD2GOBP_Protein_Localization_To_Cell_PeripheryHumanSkinP5_rep1 2.4e-09
SAPCD2GOBP_Establishment_Of_Cell_PolarityHumanSkinP5_rep3 1.8e-12
SAPCD2GOBP_Morphogenesis_Of_A_Polarized_EpitheliumHumanSkinP5_rep3 2.7e-08
SAPCD2GOBP_Protein_Localization_To_Cell_CortexHumanSkinP5_rep3 2.3e-10
SAPCD2GOBP_Regulation_Of_Protein_Localization_To_Cell_CortexHumanSkinP5_rep3 2.1e-12
SAPCD2GOBP_Cytoskeleton_OrganizationHumanSkinP9_rep3 3.1e-12
SAPCD2GOBP_Epithelium_DevelopmentHumanSkinP9_rep3 4.2e-08
SAPCD2GOBP_Establishment_Of_Mitotic_Spindle_LocalizationHumanSkinP10_rep1 3.2e-08
SAPCD2GOBP_Positive_Regulation_Of_Cell_Population_ProliferationHumanLungrep_1 7.3e-07

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SAPCD2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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SAPCD2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for SAPCD2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for SAPCD2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SAPCD2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource