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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: AP3D1 (spascer ID:8943)

Gene summary for AP3D1

Gene summary

Gene information
	Species	Human
	Gene symbol	AP3D1
	Gene ID	8943
	Gene name	adaptor related protein complex 3 subunit delta 1
	Synonyms	ADTD\|HPS10\|hBLVR
	Cytomap	19p13.3
	Type of gene	protein-coding
	Description	AP-3 complex subunit delta-1AP-3 complex delta subunit, partial CDSadapter-related protein complex 3 subunit delta-1adaptor related protein complex 3 delta 1 subunitdelta adaptinsubunit of putative vesicle coat adaptor complex AP-3
	Modification date	20220513
	UniProtAcc	O14617

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
AP3D1	GO:0006623	protein targeting to vacuole	21873635	Process
AP3D1	GO:0006896	Golgi to vacuole transport	21873635	Process
AP3D1	GO:0010008	endosome membrane	21873635	Component
AP3D1	GO:0016182	synaptic vesicle budding from endosome	21873635	Process
AP3D1	GO:0030123	AP-3 adaptor complex	21873635	Component
AP3D1	GO:0043195	terminal bouton	21873635	Component
AP3D1	GO:0048490	anterograde synaptic vesicle transport	21873635	Process
AP3D1	GO:0048499	synaptic vesicle membrane organization	21873635	Process
AP3D1	GO:0098830	presynaptic endosome	21873635	Component
AP3D1	GO:0098943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	21873635	Process

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Spatial pattern events for AP3D1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
AP3D1	Human	Intestine	rep_colon1	34417225	9.57e-12
AP3D1	Human	Intestine	rep_colon2	34417225	8.12e-16
AP3D1	Human	Liver	rep_liver1	34417225	5.59e-08
AP3D1	Human	Liver	rep_liver2	34417225	6.98e-16
AP3D1	Human	Liver	rep_liver4	34417225	7.71e-16
AP3D1	Human	Uterus	rep_4	34857954	4.42e-08
AP3D1	Human	Breast	1160920F	34493872	4.43e-08
AP3D1	Human	Breast	CID4290	34493872	6.33e-06
AP3D1	Human	Breast	CID44971	34493872	6.78e-09

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon2_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Liver_rep_liver4_H&E
Uterus_rep_4_H&E
Breast_1160920F_H&E
Breast_CID4290_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has AP3D1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
AP3D1	GOBP_Maintenance_Of_Location	Human	Brain	rep_1	2.8e-23
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
AP3D1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Brain	rep_1	4.6e-05
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Brain	rep_1	1.1e-18
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Brain	rep_4	4.1e-17
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Brain	rep_4	4.1e-17
AP3D1	GOBP_Regulation_Of_Sequestering_Of_Zinc_Ion	Human	Brain	st	8.6e-11
AP3D1	GOBP_Zinc_Ion_Homeostasis	Human	Bladder	rep_2	1.3e-09
AP3D1	GOBP_Maintenance_Of_Location	Human	Liver	rep_1	1.0e-70
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Liver	rep_1	6.0e-76
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
AP3D1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Liver	rep_1	1.1e-67
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Liver	rep_1	1.4e-67
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Liver	rep_1	1.0e-70
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	rep_colon4	1.9e-09
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
AP3D1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	rep_colon4	2.2e-52
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	rep_colon4	4.8e-23
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	rep_colon4	9.0e-12
AP3D1	GOBP_Biological_Adhesion	Human	Intestine	A3	6.7e-11
AP3D1	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
AP3D1	GOBP_Cell_Cell_Adhesion	Human	Intestine	A3	2.5e-07
AP3D1	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
AP3D1	GOBP_Developmental_Maturation	Human	Intestine	A3	2.5e-14
AP3D1	GOBP_Endomembrane_System_Organization	Human	Intestine	A3	1.6e-16
AP3D1	GOBP_Endosomal_Transport	Human	Intestine	A3	1.9e-09
AP3D1	GOBP_Establishment_Of_Organelle_Localization	Human	Intestine	A3	9.7e-13
AP3D1	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
AP3D1	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Intestine	A3	3.8e-08
AP3D1	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Human	Intestine	A3	3.5e-07
AP3D1	GOBP_Golgi_Vesicle_Transport	Human	Intestine	A3	9.2e-10
AP3D1	GOBP_Homeostatic_Process	Human	Intestine	A3	8.7e-10
AP3D1	GOBP_Immune_System_Development	Human	Intestine	A3	4.3e-10
AP3D1	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
AP3D1	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
AP3D1	GOBP_Leukocyte_Cell_Cell_Adhesion	Human	Intestine	A3	6.3e-09
AP3D1	GOBP_Leukocyte_Differentiation	Human	Intestine	A3	2.0e-07
AP3D1	GOBP_Lymphocyte_Activation	Human	Intestine	A3	1.8e-09
AP3D1	GOBP_Lysosomal_Transport	Human	Intestine	A3	7.2e-12
AP3D1	GOBP_Maintenance_Of_Location	Human	Intestine	A3	7.1e-07
AP3D1	GOBP_Maintenance_Of_Location_In_Cell	Human	Intestine	A3	6.1e-08
AP3D1	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
AP3D1	GOBP_Microtubule_Based_Process	Human	Intestine	A3	3.4e-11
AP3D1	GOBP_Mononuclear_Cell_Differentiation	Human	Intestine	A3	5.6e-08
AP3D1	GOBP_Neurotransmitter_Receptor_Transport_Postsynaptic_Endosome_To_Lysosome	Human	Intestine	A3	6.7e-07
AP3D1	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
AP3D1	GOBP_Pigmentation	Human	Intestine	A3	7.2e-07
AP3D1	GOBP_Positive_Regulation_Of_Cell_Activation	Human	Intestine	A3	6.6e-07
AP3D1	GOBP_Positive_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	4.4e-10
AP3D1	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Intestine	A3	5.1e-10
AP3D1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.6e-14
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Intestine	A3	1.5e-12
AP3D1	GOBP_Positive_Regulation_Of_Hemopoiesis	Human	Intestine	A3	4.3e-16
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Intestine	A3	6.8e-15
AP3D1	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Intestine	A3	4.0e-07
AP3D1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Intestine	A3	8.6e-17
AP3D1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Intestine	A3	5.1e-13
AP3D1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Intestine	A3	9.4e-13
AP3D1	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Intestine	A3	1.9e-10
AP3D1	GOBP_Protein_Containing_Complex_Localization	Human	Intestine	A3	6.4e-12
AP3D1	GOBP_Protein_Localization_To_Lysosome	Human	Intestine	A3	9.2e-09
AP3D1	GOBP_Protein_Localization_To_Organelle	Human	Intestine	A3	1.5e-12
AP3D1	GOBP_Protein_Targeting	Human	Intestine	A3	6.5e-09
AP3D1	GOBP_Regulation_Of_Cell_Activation	Human	Intestine	A3	1.8e-08
AP3D1	GOBP_Regulation_Of_Cell_Adhesion	Human	Intestine	A3	1.5e-10
AP3D1	GOBP_Regulation_Of_Cell_Cell_Adhesion	Human	Intestine	A3	1.2e-07
AP3D1	GOBP_Regulation_Of_Cell_Differentiation	Human	Intestine	A3	1.7e-10
AP3D1	GOBP_Regulation_Of_Hemopoiesis	Human	Intestine	A3	3.4e-15
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Intestine	A3	1.5e-15
AP3D1	GOBP_Regulation_Of_Leukocyte_Differentiation	Human	Intestine	A3	7.0e-14
AP3D1	GOBP_Regulation_Of_Lymphocyte_Activation	Human	Intestine	A3	4.0e-08
AP3D1	GOBP_Regulation_Of_Lymphocyte_Differentiation	Human	Intestine	A3	1.9e-11
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Intestine	A3	1.8e-14
AP3D1	GOBP_Regulation_Of_Sequestering_Of_Zinc_Ion	Human	Intestine	A3	5.1e-07
AP3D1	GOBP_Regulation_Of_T_Cell_Activation	Human	Intestine	A3	9.9e-08
AP3D1	GOBP_Regulation_Of_T_Cell_Differentiation	Human	Intestine	A3	2.2e-07
AP3D1	GOBP_T_Cell_Activation	Human	Intestine	A3	1.2e-07
AP3D1	GOBP_T_Cell_Differentiation	Human	Intestine	A3	8.1e-08
AP3D1	GOBP_Vacuolar_Transport	Human	Intestine	A3	4.3e-14
AP3D1	GOBP_Vesicle_Localization	Human	Intestine	A3	1.3e-07
AP3D1	GOBP_Vesicle_Organization	Human	Intestine	A3	3.0e-15
AP3D1	GOBP_Alpha_Beta_T_Cell_Activation	Human	Intestine	A8	1.0e-10
AP3D1	GOBP_Alpha_Beta_T_Cell_Differentiation	Human	Intestine	A8	5.3e-14
AP3D1	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
AP3D1	GOBP_Antigen_Processing_And_Presentation_Via_Mhc_Class_Ib	Human	Intestine	A8	3.7e-08
AP3D1	GOBP_Cellular_Homeostasis	Human	Intestine	A8	2.1e-11
AP3D1	GOBP_Cellular_Ion_Homeostasis	Human	Intestine	A8	4.3e-12
AP3D1	GOBP_Cellular_Pigmentation	Human	Intestine	A8	4.6e-18
AP3D1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Intestine	A8	1.4e-07
AP3D1	GOBP_Chemical_Homeostasis	Human	Intestine	A8	1.3e-12
AP3D1	GOBP_Developmental_Pigmentation	Human	Intestine	A8	2.8e-13
AP3D1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Intestine	A8	1.0e-12
AP3D1	GOBP_Golgi_To_Vacuole_Transport	Human	Intestine	A8	6.5e-20
AP3D1	GOBP_Ion_Homeostasis	Human	Intestine	A8	6.1e-15
AP3D1	GOBP_Metal_Ion_Homeostasis	Human	Intestine	A8	2.2e-10
AP3D1	GOBP_Microtubule_Based_Movement	Human	Intestine	A8	2.9e-10
AP3D1	GOBP_Neurotransmitter_Receptor_Transport	Human	Intestine	A8	5.8e-13
AP3D1	GOBP_Nk_T_Cell_Differentiation	Human	Intestine	A8	3.3e-11
AP3D1	GOBP_Pigment_Accumulation	Human	Intestine	A8	1.8e-11
AP3D1	GOBP_Pigment_Cell_Differentiation	Human	Intestine	A8	1.7e-20
AP3D1	GOBP_Pigment_Granule_Maturation	Human	Intestine	A8	7.3e-22
AP3D1	GOBP_Positive_Regulation_Of_Alpha_Beta_T_Cell_Activation	Human	Intestine	A8	1.8e-15
AP3D1	GOBP_Positive_Regulation_Of_Lymphocyte_Differentiation	Human	Intestine	A8	3.0e-15
AP3D1	GOBP_Protein_Localization_To_Vacuole	Human	Intestine	A8	2.3e-10
AP3D1	GOBP_Protein_Targeting_To_Vacuole	Human	Intestine	A8	1.9e-20
AP3D1	GOBP_Regulation_Of_Alpha_Beta_T_Cell_Activation	Human	Intestine	A8	3.5e-16
AP3D1	GOBP_Regulation_Of_Alpha_Beta_T_Cell_Differentiation	Human	Intestine	A8	5.0e-17
AP3D1	GOBP_Regulation_Of_Nk_T_Cell_Differentiation	Human	Intestine	A8	4.0e-17
AP3D1	GOBP_Sequestering_Of_Zinc_Ion	Human	Intestine	A8	3.0e-14
AP3D1	GOBP_Synaptic_Vesicle_Budding	Human	Intestine	A8	6.1e-14
AP3D1	GOBP_Synaptic_Vesicle_Cytoskeletal_Transport	Human	Intestine	A8	5.4e-07
AP3D1	GOBP_Synaptic_Vesicle_Endosomal_Processing	Human	Intestine	A8	8.2e-12
AP3D1	GOBP_Synaptic_Vesicle_Localization	Human	Intestine	A8	5.7e-08
AP3D1	GOBP_Synaptic_Vesicle_Recycling_Via_Endosome	Human	Intestine	A8	2.1e-32
AP3D1	GOBP_Synaptic_Vesicle_Transport	Human	Intestine	A8	1.1e-08
AP3D1	GOBP_Vesicle_Budding_From_Membrane	Human	Intestine	A8	4.3e-15
AP3D1	GOBP_Vesicle_Cytoskeletal_Trafficking	Human	Intestine	A8	5.1e-14
AP3D1	GOBP_Vesicle_Transport_Along_Microtubule	Human	Intestine	A8	1.1e-11
AP3D1	GOBP_Zinc_Ion_Homeostasis	Human	Intestine	A8	3.2e-15
AP3D1	GOBP_Cellular_Pigmentation	Human	Pancreas	PDAC-B-st1	4.5e-05
AP3D1	GOBP_Microtubule_Based_Transport	Human	Pancreas	PDAC-B-st1	2.2e-05
AP3D1	GOBP_Pigment_Granule_Maturation	Human	Pancreas	PDAC-B-st1	8.8e-05
AP3D1	GOBP_Protein_Targeting	Human	Pancreas	PDAC-B-st1	9.4e-05
AP3D1	GOBP_Synaptic_Vesicle_Localization	Human	Pancreas	PDAC-B-st1	3.6e-05
AP3D1	GOBP_Transition_Metal_Ion_Homeostasis	Human	Pancreas	PDAC-B-st1	1.1e-05
AP3D1	GOBP_Transport_Along_Microtubule	Human	Pancreas	PDAC-B-st1	2.0e-05
AP3D1	GOBP_Vesicle_Transport_Along_Microtubule	Human	Pancreas	PDAC-B-st1	1.8e-05
AP3D1	GOBP_Endosomal_Transport	Human	Pancreas	PDAC-A-st2	9.1e-05
AP3D1	GOBP_Golgi_To_Vacuole_Transport	Human	Pancreas	PDAC-A-st2	4.2e-06
AP3D1	GOBP_Synaptic_Vesicle_Budding	Human	Pancreas	PDAC-A-st2	1.5e-05
AP3D1	GOBP_Synaptic_Vesicle_Recycling_Via_Endosome	Human	Pancreas	PDAC-A-st2	1.1e-05
AP3D1	GOBP_Zinc_Ion_Homeostasis	Human	Pancreas	PDAC-A-st2	1.5e-05
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Uterus	rep_4	5.1e-31
AP3D1	GOBP_Nk_T_Cell_Differentiation	Human	Uterus	rep_2	7.1e-07
AP3D1	GOBP_Alpha_Beta_T_Cell_Differentiation	Human	Uterus	rep_25	7.6e-09
AP3D1	GOBP_Antigen_Processing_And_Presentation_Of_Lipid_Antigen_Via_Mhc_Class_Ib	Human	Uterus	rep_25	1.2e-14
AP3D1	GOBP_Developmental_Pigmentation	Human	Uterus	rep_25	1.6e-09
AP3D1	GOBP_Pigment_Accumulation	Human	Uterus	rep_25	1.4e-11
AP3D1	GOBP_Pigment_Cell_Differentiation	Human	Uterus	rep_25	4.8e-06
AP3D1	GOBP_Pigment_Granule_Maturation	Human	Uterus	rep_25	1.7e-09
AP3D1	GOBP_Positive_Regulation_Of_Alpha_Beta_T_Cell_Differentiation	Human	Uterus	rep_25	7.5e-09
AP3D1	GOBP_Positive_Regulation_Of_Hemopoiesis	Human	Uterus	rep_25	2.5e-09
AP3D1	GOBP_Positive_Regulation_Of_Lymphocyte_Differentiation	Human	Uterus	rep_25	9.8e-06
AP3D1	GOBP_Regulation_Of_Alpha_Beta_T_Cell_Differentiation	Human	Uterus	rep_25	8.2e-07
AP3D1	GOBP_Regulation_Of_Leukocyte_Differentiation	Human	Uterus	rep_25	2.2e-06
AP3D1	GOBP_Regulation_Of_Nk_T_Cell_Differentiation	Human	Uterus	rep_25	1.6e-06
AP3D1	GOBP_Regulation_Of_Sequestering_Of_Zinc_Ion	Human	Uterus	rep_25	1.9e-16
AP3D1	GOBP_Synaptic_Vesicle_Endosomal_Processing	Human	Uterus	rep_25	1.5e-06
AP3D1	GOBP_Cellular_Pigmentation	Human	Uterus	rep_26	4.4e-11
AP3D1	GOBP_Developmental_Maturation	Human	Uterus	rep_26	1.1e-06
AP3D1	GOBP_Endosomal_Transport	Human	Uterus	rep_26	1.1e-06
AP3D1	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Human	Uterus	rep_26	3.7e-10
AP3D1	GOBP_Golgi_Vesicle_Transport	Human	Uterus	rep_26	3.4e-14
AP3D1	GOBP_Homeostatic_Process	Human	Uterus	rep_26	1.9e-07
AP3D1	GOBP_Immune_System_Development	Human	Uterus	rep_26	1.0e-06
AP3D1	GOBP_Leukocyte_Differentiation	Human	Uterus	rep_26	1.4e-08
AP3D1	GOBP_Lysosomal_Transport	Human	Uterus	rep_26	1.3e-08
AP3D1	GOBP_Mononuclear_Cell_Differentiation	Human	Uterus	rep_26	2.1e-10
AP3D1	GOBP_Neurotransmitter_Receptor_Transport	Human	Uterus	rep_26	6.2e-18
AP3D1	GOBP_Organelle_Transport_Along_Microtubule	Human	Uterus	rep_26	4.4e-06
AP3D1	GOBP_Pigment_Granule_Organization	Human	Uterus	rep_26	1.3e-08
AP3D1	GOBP_Pigmentation	Human	Uterus	rep_26	2.0e-09
AP3D1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_26	1.6e-09
AP3D1	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Uterus	rep_26	4.4e-08
AP3D1	GOBP_Protein_Targeting_To_Vacuole	Human	Uterus	rep_26	1.1e-11
AP3D1	GOBP_Regulation_Of_Hemopoiesis	Human	Uterus	rep_26	4.0e-09
AP3D1	GOBP_Regulation_Of_Lymphocyte_Differentiation	Human	Uterus	rep_26	7.9e-09
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Uterus	rep_26	7.3e-07
AP3D1	GOBP_Regulation_Of_T_Cell_Differentiation	Human	Uterus	rep_26	9.8e-09
AP3D1	GOBP_Synaptic_Vesicle_Recycling_Via_Endosome	Human	Uterus	rep_26	4.1e-17
AP3D1	GOBP_T_Cell_Differentiation	Human	Uterus	rep_26	5.5e-07
AP3D1	GOBP_Vacuolar_Transport	Human	Uterus	rep_26	2.2e-09
AP3D1	GOBP_Vesicle_Transport_Along_Microtubule	Human	Uterus	rep_26	6.3e-11
AP3D1	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
AP3D1	GOBP_Lymphocyte_Activation	Human	Uterus	rep_28	6.6e-07
AP3D1	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Uterus	rep_28	5.4e-06
AP3D1	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Uterus	rep_28	9.7e-06
AP3D1	GOBP_Regulation_Of_Alpha_Beta_T_Cell_Activation	Human	Uterus	rep_28	8.2e-06
AP3D1	GOBP_Regulation_Of_Lymphocyte_Activation	Human	Uterus	rep_28	6.6e-07
AP3D1	GOBP_Sequestering_Of_Metal_Ion	Human	Uterus	rep_28	7.5e-12
AP3D1	GOBP_Biological_Adhesion	Human	Uterus	rep_29	3.3e-06
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Uterus	rep_29	8.8e-06
AP3D1	GOBP_Regulation_Of_Cell_Differentiation	Human	Uterus	rep_29	2.8e-06
AP3D1	GOBP_Biological_Adhesion	Human	Breast	rep_1	4.0e-110
AP3D1	GOBP_Cell_Cell_Adhesion	Human	Breast	rep_1	3.6e-45
AP3D1	GOBP_Cellular_Homeostasis	Human	Breast	rep_1	2.8e-10
AP3D1	GOBP_Cellular_Ion_Homeostasis	Human	Breast	rep_1	7.6e-24
AP3D1	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
AP3D1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Breast	rep_1	6.0e-07
AP3D1	GOBP_Chemical_Homeostasis	Human	Breast	rep_1	4.8e-18
AP3D1	GOBP_Developmental_Pigmentation	Human	Breast	rep_1	1.2e-35
AP3D1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Breast	rep_1	1.2e-25
AP3D1	GOBP_Endomembrane_System_Organization	Human	Breast	rep_1	2.2e-04
AP3D1	GOBP_Establishment_Of_Organelle_Localization	Human	Breast	rep_1	6.5e-08
AP3D1	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
AP3D1	GOBP_Homeostatic_Process	Human	Breast	rep_1	9.0e-53
AP3D1	GOBP_Immune_System_Development	Human	Breast	rep_1	1.0e-31
AP3D1	GOBP_Ion_Homeostasis	Human	Breast	rep_1	1.4e-53
AP3D1	GOBP_Maintenance_Of_Location	Human	Breast	rep_1	3.8e-39
AP3D1	GOBP_Maintenance_Of_Location_In_Cell	Human	Breast	rep_1	1.4e-24
AP3D1	GOBP_Metal_Ion_Homeostasis	Human	Breast	rep_1	6.8e-70
AP3D1	GOBP_Neurotransmitter_Receptor_Transport	Human	Breast	rep_1	4.6e-23
AP3D1	GOBP_Neurotransmitter_Receptor_Transport_Postsynaptic_Endosome_To_Lysosome	Human	Breast	rep_1	1.3e-67
AP3D1	GOBP_Nk_T_Cell_Differentiation	Human	Breast	rep_1	3.7e-115
AP3D1	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
AP3D1	GOBP_Pigment_Cell_Differentiation	Human	Breast	rep_1	6.6e-19
AP3D1	GOBP_Positive_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	7.1e-96
AP3D1	GOBP_Positive_Regulation_Of_Developmental_Process	Human	Breast	rep_1	1.4e-85
AP3D1	GOBP_Positive_Regulation_Of_Multicellular_Organismal_Process	Human	Breast	rep_1	5.8e-20
AP3D1	GOBP_Protein_Localization_To_Lysosome	Human	Breast	rep_1	4.0e-17
AP3D1	GOBP_Protein_Localization_To_Vacuole	Human	Breast	rep_1	3.2e-17
AP3D1	GOBP_Regulation_Of_Cell_Adhesion	Human	Breast	rep_1	1.7e-16
AP3D1	GOBP_Regulation_Of_Cell_Differentiation	Human	Breast	rep_1	2.5e-42
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Breast	rep_1	4.5e-113
AP3D1	GOBP_Regulation_Of_Nk_T_Cell_Differentiation	Human	Breast	rep_1	5.1e-46
AP3D1	GOBP_Regulation_Of_Sequestering_Of_Zinc_Ion	Human	Breast	rep_1	1.8e-26
AP3D1	GOBP_Sequestering_Of_Zinc_Ion	Human	Breast	rep_1	3.8e-95
AP3D1	GOBP_Synaptic_Vesicle_Endosomal_Processing	Human	Breast	rep_1	1.1e-33
AP3D1	GOBP_Synaptic_Vesicle_Recycling	Human	Breast	rep_1	2.7e-155
AP3D1	GOBP_Transition_Metal_Ion_Homeostasis	Human	Breast	rep_1	1.1e-30
AP3D1	GOBP_Vesicle_Budding_From_Membrane	Human	Breast	rep_1	1.7e-07
AP3D1	GOBP_Vesicle_Cytoskeletal_Trafficking	Human	Breast	rep_1	1.4e-04
AP3D1	GOBP_Vesicle_Localization	Human	Breast	rep_1	7.0e-11
AP3D1	GOBP_Vesicle_Mediated_Transport_In_Synapse	Human	Breast	rep_1	6.1e-127
AP3D1	GOBP_Vesicle_Organization	Human	Breast	rep_1	8.3e-15
AP3D1	GOBP_Alpha_Beta_T_Cell_Differentiation	Human	Breast	rep_2	1.2e-04
AP3D1	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Breast	rep_2	2.3e-04
AP3D1	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Breast	rep_2	5.9e-07
AP3D1	GOBP_Anterograde_Axonal_Transport	Human	Breast	rep_5	2.2e-04
AP3D1	GOBP_Antigen_Processing_And_Presentation_Of_Lipid_Antigen_Via_Mhc_Class_Ib	Human	Breast	rep_5	2.8e-13
AP3D1	GOBP_Developmental_Maturation	Human	Breast	rep_5	2.3e-12
AP3D1	GOBP_Establishment_Of_Protein_Localization_To_Vacuole	Human	Breast	rep_5	2.0e-13
AP3D1	GOBP_Golgi_To_Vacuole_Transport	Human	Breast	rep_5	1.6e-14
AP3D1	GOBP_Lysosomal_Transport	Human	Breast	rep_5	9.9e-17
AP3D1	GOBP_Pigment_Accumulation	Human	Breast	rep_5	8.7e-08
AP3D1	GOBP_Pigment_Granule_Maturation	Human	Breast	rep_5	2.4e-06
AP3D1	GOBP_Positive_Regulation_Of_Nucleobase_Containing_Compound_Metabolic_Process	Human	Breast	rep_5	8.0e-09
AP3D1	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Breast	rep_5	8.2e-04
AP3D1	GOBP_Protein_Targeting_To_Vacuole	Human	Breast	rep_5	6.4e-13
AP3D1	GOBP_Synaptic_Vesicle_Budding	Human	Breast	rep_5	4.8e-04
AP3D1	GOBP_Synaptic_Vesicle_Recycling_Via_Endosome	Human	Breast	rep_5	1.7e-25
AP3D1	GOBP_Vacuolar_Transport	Human	Breast	rep_5	6.0e-13
AP3D1	GOBP_Axo_Dendritic_Transport	Human	Breast	rep_6	1.5e-05
AP3D1	GOBP_Cellular_Pigmentation	Human	Breast	rep_6	9.2e-06
AP3D1	GOBP_Endosomal_Transport	Human	Breast	rep_6	1.7e-13
AP3D1	GOBP_Establishment_Of_Protein_Localization_To_Organelle	Human	Breast	rep_6	8.5e-11
AP3D1	GOBP_Golgi_Vesicle_Transport	Human	Breast	rep_6	2.0e-08
AP3D1	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
AP3D1	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
AP3D1	GOBP_Microtubule_Based_Movement	Human	Breast	rep_6	8.5e-09
AP3D1	GOBP_Microtubule_Based_Process	Human	Breast	rep_6	1.8e-04
AP3D1	GOBP_Microtubule_Based_Transport	Human	Breast	rep_6	2.9e-09
AP3D1	GOBP_Organelle_Transport_Along_Microtubule	Human	Breast	rep_6	1.9e-05
AP3D1	GOBP_Pigment_Granule_Organization	Human	Breast	rep_6	5.8e-07
AP3D1	GOBP_Pigmentation	Human	Breast	rep_6	1.3e-05
AP3D1	GOBP_Positive_Regulation_Of_Transcription_By_Rna_Polymerase_Ii	Human	Breast	rep_6	4.2e-06
AP3D1	GOBP_Protein_Containing_Complex_Localization	Human	Breast	rep_6	1.3e-06
AP3D1	GOBP_Protein_Localization_To_Organelle	Human	Breast	rep_6	1.1e-07
AP3D1	GOBP_Protein_Targeting	Human	Breast	rep_6	5.5e-10
AP3D1	GOBP_Synaptic_Vesicle_Cytoskeletal_Transport	Human	Breast	rep_6	1.8e-08
AP3D1	GOBP_Synaptic_Vesicle_Localization	Human	Breast	rep_6	1.7e-08
AP3D1	GOBP_Synaptic_Vesicle_Transport	Human	Breast	rep_6	2.1e-11
AP3D1	GOBP_Transport_Along_Microtubule	Human	Breast	rep_6	1.5e-05
AP3D1	GOBP_Vesicle_Transport_Along_Microtubule	Human	Breast	rep_6	3.3e-06
AP3D1	GOBP_Zinc_Ion_Homeostasis	Human	Breast	rep_6	3.5e-08
AP3D1	GOBP_Maintenance_Of_Location_In_Cell	Human	Skin	P2_rep1	9.7e-09
AP3D1	GOBP_Sequestering_Of_Zinc_Ion	Human	Skin	P2_rep1	1.2e-10
AP3D1	GOBP_Neurotransmitter_Receptor_Transport	Human	Skin	P2_rep2	5.1e-08
AP3D1	GOBP_Divalent_Inorganic_Cation_Homeostasis	Human	Skin	P2_rep3	1.3e-08
AP3D1	GOBP_Microtubule_Based_Movement	Human	Skin	P5_rep1	2.1e-08
AP3D1	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
AP3D1	GOBP_Organelle_Transport_Along_Microtubule	Human	Skin	P5_rep1	7.4e-08
AP3D1	GOBP_Vesicle_Cytoskeletal_Trafficking	Human	Skin	P5_rep1	1.7e-12
AP3D1	GOBP_Vesicle_Localization	Human	Skin	P5_rep1	2.7e-08
AP3D1	GOBP_Vesicle_Organization	Human	Skin	P5_rep1	2.3e-09
AP3D1	GOBP_Axo_Dendritic_Transport	Human	Skin	P5_rep3	4.8e-11
AP3D1	GOBP_Microtubule_Based_Transport	Human	Skin	P5_rep3	8.3e-08
AP3D1	GOBP_Transport_Along_Microtubule	Human	Skin	P5_rep3	7.3e-13
AP3D1	GOBP_T_Cell_Differentiation	Human	Skin	P10_rep1	2.6e-08
AP3D1	GOBP_Antigen_Processing_And_Presentation_Via_Mhc_Class_Ib	Human	Skin	P10_rep2	1.4e-18
AP3D1	GOBP_Neurotransmitter_Receptor_Transport_Postsynaptic_Endosome_To_Lysosome	Human	Skin	P10_rep2	7.0e-09
AP3D1	GOBP_Nk_T_Cell_Differentiation	Human	Skin	P10_rep2	9.5e-08
AP3D1	GOBP_Regulation_Of_Sequestering_Of_Zinc_Ion	Human	Skin	P10_rep2	8.6e-10
AP3D1	GOBP_Synaptic_Vesicle_Recycling_Via_Endosome	Human	Skin	P10_rep2	4.8e-08
AP3D1	GOBP_Mononuclear_Cell_Differentiation	Human	Skin	P10_rep3	6.1e-09
AP3D1	GOBP_Regulation_Of_Leukocyte_Differentiation	Human	Skin	P10_rep3	9.1e-10
AP3D1	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
AP3D1	GOBP_Ion_Homeostasis	Human	Lung	rep_1	6.1e-07
AP3D1	GOBP_Leukocyte_Differentiation	Human	Lung	rep_1	9.7e-07
AP3D1	GOBP_Positive_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	3.1e-08
AP3D1	GOBP_Regulation_Of_Immune_System_Process	Human	Lung	rep_1	5.9e-07
AP3D1	GOBP_Regulation_Of_Leukocyte_Differentiation	Human	Lung	rep_1	2.2e-07
AP3D1	GOBP_Synaptic_Vesicle_Budding	Human	Lung	rep_1	1.8e-07
AP3D1	GOBP_Alpha_Beta_T_Cell_Activation	Human	Lung	rep_2	2.2e-07
AP3D1	GOBP_Biological_Adhesion	Human	Lung	rep_2	6.6e-07
AP3D1	GOBP_Cell_Cell_Adhesion	Human	Lung	rep_2	5.3e-07
AP3D1	GOBP_Cellular_Homeostasis	Human	Lung	rep_2	7.3e-07
AP3D1	GOBP_Cellular_Transition_Metal_Ion_Homeostasis	Human	Lung	rep_2	5.1e-07
AP3D1	GOBP_Immune_System_Development	Human	Lung	rep_2	7.9e-07
AP3D1	GOBP_Lysosomal_Transport	Human	Lung	rep_2	4.5e-09
AP3D1	GOBP_Maintenance_Of_Location	Human	Lung	rep_2	1.1e-08
AP3D1	GOBP_Maintenance_Of_Location_In_Cell	Human	Lung	rep_2	2.8e-08
AP3D1	GOBP_Mononuclear_Cell_Differentiation	Human	Lung	rep_2	2.5e-07
AP3D1	GOBP_Positive_Regulation_Of_Cell_Activation	Human	Lung	rep_2	1.0e-07
AP3D1	GOBP_Positive_Regulation_Of_Cell_Cell_Adhesion	Human	Lung	rep_2	8.2e-08
AP3D1	GOBP_Positive_Regulation_Of_Hemopoiesis	Human	Lung	rep_2	2.8e-09
AP3D1	GOBP_Positive_Regulation_Of_Leukocyte_Cell_Cell_Adhesion	Human	Lung	rep_2	4.4e-07
AP3D1	GOBP_Regulation_Of_Hemopoiesis	Human	Lung	rep_2	1.5e-07
AP3D1	GOBP_Regulation_Of_Multicellular_Organismal_Development	Human	Lung	rep_2	9.5e-07
AP3D1	GOBP_T_Cell_Differentiation	Human	Lung	rep_2	4.5e-07
AP3D1	GOBP_Vacuolar_Transport	Human	Lung	rep_2	8.0e-08

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AP3D1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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AP3D1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for AP3D1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for AP3D1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for AP3D1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
AP3D1	C0001916	Albinism	1	GENOMICS_ENGLAND
AP3D1	C0005818	Blood Platelet Disorders	1	GENOMICS_ENGLAND
AP3D1	C0027947	Neutropenia	1	GENOMICS_ENGLAND
AP3D1	C0036572	Seizures	1	GENOMICS_ENGLAND
AP3D1	C0078917	Albinism, Ocular	1	ORPHANET
AP3D1	C0079504	Hermanski-Pudlak Syndrome	1	CTD_human;GENOMICS_ENGLAND
AP3D1	C4310746	HERMANSKY-PUDLAK SYNDROME 10	1	GENOMICS_ENGLAND