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Spatial pattern gene: SKAP2 (spascer ID:8935) |
Gene summary for SKAP2 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | SKAP2 | Gene ID | 8935 |
| Gene name | src kinase associated phosphoprotein 2 |
| Synonyms | PRAP|RA70|SAPS|SCAP2|SKAP-HOM|SKAP55R |
| Cytomap | 7p15.2 |
| Type of gene | protein-coding |
| Description | src kinase-associated phosphoprotein 2Fyn-associated phosphoprotein SKAP55 homologuePyk2/RAFTK-associated proteinSKAP-55HOMSKAP55 homologretinoic acid-induced protein 70src family-associated phosphoprotein 2src kinase-associated phosphoprotein of 5 |
| Modification date | 20220513 |
| UniProtAcc | O75563 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
| SKAP2 | GO:0005737 | cytoplasm | 21873635 | Component |
| SKAP2 | GO:0005886 | plasma membrane | 21873635 | Component |
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Spatial pattern events for SKAP2 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| SKAP2 | Human | Intestine | rep_colon4 | 34417225 | 6.16e-06 |
| SKAP2 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| SKAP2 | Human | Breast | CID4465 | 34493872 | 5.98e-12 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver2_H&E  |  |
Breast_CID4465_H&E  |  |
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Spatial pattern pathway has SKAP2 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| SKAP2 | GOBP_B_Cell_Activation | Human | Intestine | A3 | 1.4e-11 |
| SKAP2 | GOBP_Cell_Activation | Human | Intestine | A3 | 6.2e-08 |
| SKAP2 | GOBP_Lymphocyte_Activation | Human | Intestine | A3 | 1.8e-09 |
| SKAP2 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Human | Intestine | A3 | 5.4e-19 |
| SKAP2 | GOBP_Cell_Activation | Human | Uterus | rep_28 | 2.5e-06 |
| SKAP2 | GOBP_Lymphocyte_Activation | Human | Uterus | rep_28 | 6.6e-07 |
| SKAP2 | GOBP_Negative_Regulation_Of_Cell_Population_Proliferation | Human | Breast | rep_1 | 1.3e-54 |
| SKAP2 | GOBP_Cell_Activation | Human | Lung | rep_1 | 2.1e-08 |
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SKAP2 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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SKAP2 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for SKAP2 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for SKAP2 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for SKAP2 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| SKAP2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
