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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: AP1M1 (spascer ID:8907)

Gene summary for AP1M1

Gene summary

Gene information
	Species	Human
	Gene symbol	AP1M1
	Gene ID	8907
	Gene name	adaptor related protein complex 1 subunit mu 1
	Synonyms	AP47\|CLAPM2\|CLTNM\|MU-1A\|mu1A
	Cytomap	19p13.11
	Type of gene	protein-coding
	Description	AP-1 complex subunit mu-1AP-mu chain family member mu1AHA1 47 kDa subunitadapter-related protein complex 1 subunit mu-1adaptor protein complex AP-1 mu-1 subunitadaptor protein complex AP-1 subunit mu-1adaptor related protein complex 1 mu 1 subunitc
	Modification date	20220513
	UniProtAcc	Q9BXS5

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
AP1M1	GO:0016192	vesicle-mediated transport	21873635	Process
AP1M1	GO:0030136	clathrin-coated vesicle	21873635	Component
AP1M1	GO:0031410	cytoplasmic vesicle	21873635	Component
AP1M1	GO:0035615	clathrin adaptor activity	21873635	Function

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Spatial pattern events for AP1M1

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
AP1M1	Human	Intestine	rep_colon2	34417225	2.85e-15
AP1M1	Human	Liver	rep_liver1	34417225	3.14e-08
AP1M1	Human	Liver	rep_liver2	34417225	6.98e-16
AP1M1	Human	Uterus	rep_3	34857954	1.74e-07
AP1M1	Human	Breast	1160920F	34493872	3.31e-12
AP1M1	Human	Breast	CID44971	34493872	9.74e-10

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon2_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Uterus_rep_3_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has AP1M1 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
AP1M1	GOBP_Immune_Effector_Process	Human	Brain	rep_1	8.1e-16
AP1M1	GOBP_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	8.1e-16
AP1M1	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Brain	rep_1	2.8e-23
AP1M1	GOBP_Immune_Effector_Process	Human	Liver	rep_1	9.0e-62
AP1M1	GOBP_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	9.0e-62
AP1M1	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Liver	rep_1	1.0e-70
AP1M1	GOBP_Immune_Effector_Process	Human	Intestine	rep_colon4	1.3e-27
AP1M1	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	rep_colon4	1.3e-27
AP1M1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Intestine	A3	3.5e-14
AP1M1	GOBP_Cell_Activation	Human	Intestine	A3	6.2e-08
AP1M1	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Intestine	A3	4.0e-14
AP1M1	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
AP1M1	GOBP_Developmental_Maturation	Human	Intestine	A3	2.5e-14
AP1M1	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
AP1M1	GOBP_Exocytosis	Human	Intestine	A3	4.7e-10
AP1M1	GOBP_Immune_Effector_Process	Human	Intestine	A3	3.9e-14
AP1M1	GOBP_Intracellular_Protein_Transport	Human	Intestine	A3	4.8e-12
AP1M1	GOBP_Intracellular_Transport	Human	Intestine	A3	7.6e-15
AP1M1	GOBP_Leukocyte_Mediated_Immunity	Human	Intestine	A3	8.2e-10
AP1M1	GOBP_Pigmentation	Human	Intestine	A3	7.2e-07
AP1M1	GOBP_Secretion	Human	Intestine	A3	1.8e-13
AP1M1	GOBP_Vesicle_Organization	Human	Intestine	A3	3.0e-15
AP1M1	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
AP1M1	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Intestine	A8	8.9e-10
AP1M1	GOBP_Cellular_Pigmentation	Human	Intestine	A8	4.6e-18
AP1M1	GOBP_Developmental_Pigmentation	Human	Intestine	A8	2.8e-13
AP1M1	GOBP_Myeloid_Leukocyte_Activation	Human	Intestine	A8	3.8e-18
AP1M1	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Intestine	A8	8.5e-11
AP1M1	GOBP_Pigment_Accumulation	Human	Intestine	A8	1.8e-11
AP1M1	GOBP_Pigment_Cell_Differentiation	Human	Intestine	A8	1.7e-20
AP1M1	GOBP_Pigment_Granule_Maturation	Human	Intestine	A8	7.3e-22
AP1M1	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Pancreas	PDAC-B-st1	7.1e-05
AP1M1	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Pancreas	PDAC-B-st1	1.2e-05
AP1M1	GOBP_Cellular_Pigmentation	Human	Pancreas	PDAC-B-st1	4.5e-05
AP1M1	GOBP_Pigment_Granule_Maturation	Human	Pancreas	PDAC-B-st1	8.8e-05
AP1M1	GOBP_Immune_Effector_Process	Human	Uterus	rep_4	2.0e-31
AP1M1	GOBP_Leukocyte_Mediated_Immunity	Human	Uterus	rep_4	2.0e-31
AP1M1	GOBP_Developmental_Pigmentation	Human	Uterus	rep_25	1.6e-09
AP1M1	GOBP_Pigment_Accumulation	Human	Uterus	rep_25	1.4e-11
AP1M1	GOBP_Pigment_Cell_Differentiation	Human	Uterus	rep_25	4.8e-06
AP1M1	GOBP_Pigment_Granule_Maturation	Human	Uterus	rep_25	1.7e-09
AP1M1	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Uterus	rep_26	7.6e-06
AP1M1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Uterus	rep_26	5.9e-08
AP1M1	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Uterus	rep_26	1.5e-11
AP1M1	GOBP_Cellular_Pigmentation	Human	Uterus	rep_26	4.4e-11
AP1M1	GOBP_Developmental_Maturation	Human	Uterus	rep_26	1.1e-06
AP1M1	GOBP_Exocytosis	Human	Uterus	rep_26	5.1e-10
AP1M1	GOBP_Myeloid_Leukocyte_Activation	Human	Uterus	rep_26	1.4e-11
AP1M1	GOBP_Pigment_Granule_Organization	Human	Uterus	rep_26	1.3e-08
AP1M1	GOBP_Pigmentation	Human	Uterus	rep_26	2.0e-09
AP1M1	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Antigen	Human	Uterus	rep_28	2.7e-08
AP1M1	GOBP_Cell_Activation	Human	Uterus	rep_28	2.5e-06
AP1M1	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Uterus	rep_28	8.7e-06
AP1M1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Breast	rep_1	5.4e-30
AP1M1	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
AP1M1	GOBP_Developmental_Pigmentation	Human	Breast	rep_1	1.2e-35
AP1M1	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
AP1M1	GOBP_Exocytosis	Human	Breast	rep_1	2.8e-29
AP1M1	GOBP_Myeloid_Leukocyte_Activation	Human	Breast	rep_1	2.2e-37
AP1M1	GOBP_Pigment_Cell_Differentiation	Human	Breast	rep_1	6.6e-19
AP1M1	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
AP1M1	GOBP_Vesicle_Organization	Human	Breast	rep_1	8.3e-15
AP1M1	GOBP_Developmental_Maturation	Human	Breast	rep_5	2.3e-12
AP1M1	GOBP_Pigment_Accumulation	Human	Breast	rep_5	8.7e-08
AP1M1	GOBP_Pigment_Granule_Maturation	Human	Breast	rep_5	2.4e-06
AP1M1	GOBP_Cellular_Pigmentation	Human	Breast	rep_6	9.2e-06
AP1M1	GOBP_Intracellular_Protein_Transport	Human	Breast	rep_6	6.4e-12
AP1M1	GOBP_Intracellular_Transport	Human	Breast	rep_6	1.3e-08
AP1M1	GOBP_Pigment_Granule_Organization	Human	Breast	rep_6	5.8e-07
AP1M1	GOBP_Pigmentation	Human	Breast	rep_6	1.3e-05
AP1M1	GOBP_Vesicle_Organization	Human	Skin	P5_rep1	2.3e-09
AP1M1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Skin	P9_rep2	4.7e-10
AP1M1	GOBP_Myeloid_Leukocyte_Mediated_Immunity	Human	Skin	P10_rep2	1.1e-22
AP1M1	GOBP_Biological_Process_Involved_In_Symbiotic_Interaction	Human	Lung	rep_1	2.4e-10
AP1M1	GOBP_Cell_Activation	Human	Lung	rep_1	2.1e-08
AP1M1	GOBP_Antigen_Processing_And_Presentation_Of_Peptide_Or_Polysaccharide_Antigen_Via_Mhc_Class_Ii	Human	Lung	rep_2	1.2e-07
AP1M1	GOBP_Cell_Activation_Involved_In_Immune_Response	Human	Lung	rep_2	8.0e-10

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AP1M1 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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AP1M1 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for AP1M1 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for AP1M1

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for AP1M1

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source