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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: AP1G2 (spascer ID:8906)

Gene summary for AP1G2

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

AP1G2

Gene ID

8906

Gene nameadaptor related protein complex 1 subunit gamma 2
SynonymsG2AD
Cytomap14q11.2
Type of geneprotein-coding
DescriptionAP-1 complex subunit gamma-like 2adaptor related protein complex 1 gamma 2 subunitclathrin-associated/assembly/adaptor protein, large, gamma-2gamma2-adaptin
Modification date20220513
UniProtAcc

O75843


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
AP1G2

GO:0006896

Golgi to vacuole transport

21873635

Process
AP1G2

GO:0006898

receptor-mediated endocytosis

21873635

Process
AP1G2

GO:0030121

AP-1 adaptor complex

21873635

Component
AP1G2

GO:0035615

clathrin adaptor activity

21873635

Function
AP1G2

GO:0140312

cargo adaptor activity

21873635

Function

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Spatial pattern events for AP1G2

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
AP1G2HumanBladderrep_2 343854561.33e-06
AP1G2HumanIntestinerep_colon1 344172256.48e-15
AP1G2HumanIntestinerep_colon4 344172251.14e-15
AP1G2HumanLiverrep_liver1 344172251.08e-15
AP1G2HumanLiverrep_liver2 344172256.98e-16
AP1G2HumanIntestineA1 334064093.87e-10
AP1G2HumanIntestineA2 334064091.22e-11
AP1G2HumanIntestineA4 334064097.35e-15
AP1G2HumanIntestineA8 334064092.82e-14
AP1G2HumanIntestineA9 334064093.55e-14
AP1G2HumanUterusrep_1 348579541.16e-06
AP1G2HumanUterusrep_2 348579544.63e-15
AP1G2HumanUterusrep_3 348579541.66e-15
AP1G2HumanBreast1160920F 344938721.48e-15
AP1G2HumanBreastCID4290 344938721.53e-14
AP1G2HumanBreastCID44971 344938727.10e-12

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Bladder_rep_2_H&E
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Intestine_rep_colon1_H&E
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Intestine_rep_colon4_H&E
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Liver_rep_liver1_H&E
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boxplot
Liver_rep_liver2_H&E
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Intestine_A1_H&E
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boxplot
Intestine_A2_H&E
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boxplot
Intestine_A4_H&E
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boxplot
Intestine_A8_H&E
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boxplot
Intestine_A9_H&E
boxplot

boxplot
Uterus_rep_1_H&E
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Uterus_rep_2_H&E
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boxplot
Uterus_rep_3_H&E
boxplot

boxplot
Breast_1160920F_H&E
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Breast_CID4290_H&E
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boxplot
Breast_CID44971_H&E
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Spatial pattern pathway has AP1G2 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
AP1G2GOBP_EndocytosisHumanBrainrep_1 7.4e-34
AP1G2GOBP_EndocytosisHumanLiverrep_1 1.5e-73
AP1G2GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanIntestineA3 3.5e-14
AP1G2GOBP_Cellular_Macromolecule_LocalizationHumanIntestineA3 1.7e-09
AP1G2GOBP_EndocytosisHumanIntestineA3 9.3e-10
AP1G2GOBP_Establishment_Of_Protein_LocalizationHumanIntestineA3 5.0e-10
AP1G2GOBP_Golgi_Vesicle_TransportHumanIntestineA3 9.2e-10
AP1G2GOBP_Intracellular_Protein_TransportHumanIntestineA3 4.8e-12
AP1G2GOBP_Intracellular_TransportHumanIntestineA3 7.6e-15
AP1G2GOBP_Post_Golgi_Vesicle_Mediated_TransportHumanIntestineA3 1.9e-10
AP1G2GOBP_Vacuolar_TransportHumanIntestineA3 4.3e-14
AP1G2GOBP_Golgi_To_Vacuole_TransportHumanIntestineA8 6.5e-20
AP1G2GOBP_Receptor_Mediated_EndocytosisHumanIntestineA8 6.9e-09
AP1G2GOBP_Golgi_To_Vacuole_TransportHumanPancreasPDAC-A-st2 4.2e-06
AP1G2GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanUterusrep_26 5.9e-08
AP1G2GOBP_Golgi_Vesicle_TransportHumanUterusrep_26 3.4e-14
AP1G2GOBP_Post_Golgi_Vesicle_Mediated_TransportHumanUterusrep_26 4.4e-08
AP1G2GOBP_Receptor_Mediated_EndocytosisHumanUterusrep_26 5.3e-09
AP1G2GOBP_Vacuolar_TransportHumanUterusrep_26 2.2e-09
AP1G2GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanBreastrep_1 5.4e-30
AP1G2GOBP_Cellular_Macromolecule_LocalizationHumanBreastrep_1 3.7e-09
AP1G2GOBP_Establishment_Of_Protein_LocalizationHumanBreastrep_1 7.2e-05
AP1G2GOBP_Receptor_Mediated_EndocytosisHumanBreastrep_1 2.7e-84
AP1G2GOBP_Golgi_To_Vacuole_TransportHumanBreastrep_5 1.6e-14
AP1G2GOBP_Post_Golgi_Vesicle_Mediated_TransportHumanBreastrep_5 8.2e-04
AP1G2GOBP_Vacuolar_TransportHumanBreastrep_5 6.0e-13
AP1G2GOBP_Golgi_Vesicle_TransportHumanBreastrep_6 2.0e-08
AP1G2GOBP_Intracellular_Protein_TransportHumanBreastrep_6 6.4e-12
AP1G2GOBP_Intracellular_TransportHumanBreastrep_6 1.3e-08
AP1G2GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanSkinP9_rep2 4.7e-10
AP1G2GOBP_Biological_Process_Involved_In_Symbiotic_InteractionHumanLungrep_1 2.4e-10
AP1G2GOBP_Vacuolar_TransportHumanLungrep_2 8.0e-08

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AP1G2 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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AP1G2 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for AP1G2 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for AP1G2

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for AP1G2

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource