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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

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Related drugs with this gene

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Related diseases with this gene

Spatial pattern gene: TAX1BP1 (spascer ID:8887)

Gene summary for TAX1BP1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

TAX1BP1

Gene ID

8887

Gene nameTax1 binding protein 1
SynonymsCALCOCO3|T6BP|TXBP151
Cytomap7p15.2
Type of geneprotein-coding
Descriptiontax1-binding protein 1TRAF6-binding proteinTax1 (human T-cell leukemia virus type I) binding protein 1
Modification date20220513
UniProtAcc

Q86VP1


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
TAX1BP1

GO:0043066

negative regulation of apoptotic process

21873635

Process

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Spatial pattern events for TAX1BP1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
TAX1BP1HumanIntestinerep_colon1 344172251.01e-11
TAX1BP1HumanIntestinerep_colon2 344172251.48e-15
TAX1BP1HumanIntestinerep_colon3 344172251.72e-07
TAX1BP1HumanLiverrep_liver1 344172251.08e-15
TAX1BP1HumanLiverrep_liver2 344172256.98e-16
TAX1BP1HumanLiverrep_liver4 344172257.71e-16
TAX1BP1HumanIntestineA2 334064091.11e-06
TAX1BP1HumanBreast1160920F 344938721.48e-15
TAX1BP1HumanBreastCID4290 344938726.38e-10
TAX1BP1HumanBreastCID44971 344938721.76e-15
TAX1BP1HumanSkinP5_rep2 329467852.33e-06
TAX1BP1HumanSkinP9_rep1 329467852.63e-08
TAX1BP1HumanSkinP9_rep2 329467851.89e-13
TAX1BP1HumanSkinP9_rep3 329467858.28e-06
TAX1BP1HumanLungrep_2 353550181.18e-09

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon1_H&E
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Intestine_rep_colon2_H&E
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Intestine_rep_colon3_H&E
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boxplot
Liver_rep_liver1_H&E
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boxplot
Liver_rep_liver2_H&E
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Liver_rep_liver4_H&E
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boxplot
Intestine_A2_H&E
boxplot

boxplot
Breast_1160920F_H&E
boxplot

boxplot
Breast_CID4290_H&E
boxplot

boxplot
Breast_CID44971_H&E
boxplot

boxplot
Skin_P5_rep2_H&E
boxplot

boxplot
Skin_P9_rep1_H&E
boxplot

boxplot
Skin_P9_rep2_H&E
boxplot

boxplot
Skin_P9_rep3_H&E
boxplot

boxplot
Lung_rep_2_H&E
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Spatial pattern pathway has TAX1BP1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
TAX1BP1GOBP_Negative_Regulation_Of_Molecular_FunctionHumanBrainrep_1 7.4e-34
TAX1BP1GOBP_Cytokine_ProductionHumanBrainrep_4 4.1e-17
TAX1BP1GOBP_Cytokine_ProductionHumanLiverrep_1 1.0e-70
TAX1BP1GOBP_Negative_Regulation_Of_Molecular_FunctionHumanLiverrep_1 1.5e-73
TAX1BP1GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanLiverrep_1 2.8e-53
TAX1BP1GOBP_Cytokine_ProductionHumanIntestinerep_colon4 9.0e-12
TAX1BP1GOBP_Cytokine_Mediated_Signaling_PathwayHumanIntestineA3 2.6e-09
TAX1BP1GOBP_Cytokine_ProductionHumanIntestineA3 8.9e-12
TAX1BP1GOBP_Negative_Regulation_Of_Cell_DeathHumanIntestineA3 5.8e-14
TAX1BP1GOBP_Negative_Regulation_Of_Gene_ExpressionHumanIntestineA3 2.8e-18
TAX1BP1GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanIntestineA3 6.2e-10
TAX1BP1GOBP_Regulation_Of_Cell_DeathHumanIntestineA3 7.1e-10
TAX1BP1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanIntestineA3 3.1e-19
TAX1BP1GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanIntestineA3 7.7e-20
TAX1BP1GOBP_Response_To_Tumor_Necrosis_FactorHumanIntestineA3 2.5e-09
TAX1BP1GOBP_Negative_Regulation_Of_Cytokine_ProductionHumanIntestineA8 6.2e-16
TAX1BP1GOBP_Negative_Regulation_Of_Molecular_FunctionHumanIntestineA8 4.6e-12
TAX1BP1GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_ActivityHumanIntestineA8 2.2e-12
TAX1BP1GOBP_Negative_Regulation_Of_Type_I_Interferon_ProductionHumanIntestineA8 1.3e-08
TAX1BP1GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanIntestineA8 1.1e-08
TAX1BP1GOBP_Response_To_CytokineHumanIntestineA8 1.6e-08
TAX1BP1GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanIntestineA8 1.1e-17
TAX1BP1GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_ActivityHumanUterusrep_25 7.4e-07
TAX1BP1GOBP_Cytokine_Mediated_Signaling_PathwayHumanUterusrep_26 2.0e-10
TAX1BP1GOBP_Negative_Regulation_Of_Cytokine_ProductionHumanUterusrep_26 6.8e-07
TAX1BP1GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanUterusrep_26 1.8e-07
TAX1BP1GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanUterusrep_26 2.4e-10
TAX1BP1GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanUterusrep_26 1.8e-08
TAX1BP1GOBP_Response_To_Tumor_Necrosis_FactorHumanUterusrep_26 1.5e-09
TAX1BP1GOBP_Type_I_Interferon_ProductionHumanUterusrep_26 7.8e-11
TAX1BP1GOBP_Negative_Regulation_Of_Molecular_FunctionHumanUterusrep_29 1.6e-12
TAX1BP1GOBP_Cytokine_Mediated_Signaling_PathwayHumanBreastrep_11.5e-144
TAX1BP1GOBP_Cytokine_ProductionHumanBreastrep_1 6.5e-12
TAX1BP1GOBP_Negative_Regulation_Of_Cytokine_ProductionHumanBreastrep_1 1.3e-70
TAX1BP1GOBP_Negative_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanBreastrep_1 1.1e-71
TAX1BP1GOBP_Negative_Regulation_Of_Molecular_FunctionHumanBreastrep_1 7.1e-11
TAX1BP1GOBP_Negative_Regulation_Of_Multicellular_Organismal_ProcessHumanBreastrep_1 8.3e-12
TAX1BP1GOBP_Negative_Regulation_Of_Nf_Kappab_Transcription_Factor_ActivityHumanBreastrep_1 2.1e-20
TAX1BP1GOBP_Regulation_Of_Response_To_Cytokine_StimulusHumanBreastrep_12.1e-159
TAX1BP1GOBP_Response_To_CytokineHumanBreastrep_1 2.5e-24
TAX1BP1GOBP_Response_To_Tumor_Necrosis_FactorHumanBreastrep_1 1.7e-52
TAX1BP1GOBP_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanBreastrep_1 1.8e-64
TAX1BP1GOBP_Negative_Regulation_Of_Cell_DeathHumanBreastrep_5 1.9e-07
TAX1BP1GOBP_Negative_Regulation_Of_Gene_ExpressionHumanBreastrep_5 5.3e-06
TAX1BP1GOBP_Negative_Regulation_Of_Type_I_Interferon_ProductionHumanBreastrep_5 6.4e-08
TAX1BP1GOBP_Regulation_Of_Cell_DeathHumanBreastrep_5 9.8e-08
TAX1BP1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanBreastrep_5 8.2e-07
TAX1BP1GOBP_Regulation_Of_Tumor_Necrosis_Factor_Mediated_Signaling_PathwayHumanBreastrep_6 1.0e-05
TAX1BP1GOBP_Type_I_Interferon_ProductionHumanBreastrep_6 3.7e-04
TAX1BP1GOBP_Type_I_Interferon_ProductionHumanSkinP10_rep1 8.1e-10
TAX1BP1GOBP_Negative_Regulation_Of_Cytokine_ProductionHumanLungrep_1 8.4e-07
TAX1BP1GOBP_Regulation_Of_Dna_Binding_Transcription_Factor_ActivityHumanLungrep_1 1.9e-10

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TAX1BP1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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TAX1BP1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for TAX1BP1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for TAX1BP1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for TAX1BP1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource