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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: RAB34 (spascer ID:83871)

Gene summary for RAB34

Gene summary

Gene information
	Species	Human
	Gene symbol	RAB34
	Gene ID	83871
	Gene name	RAB34, member RAS oncogene family
	Synonyms	NARR\|RAB39\|RAH
	Cytomap	17q11.2
	Type of gene	protein-coding
	Description	ras-related protein Rab-34nine amino-acid residue-repeatsras-related protein Rab-39ras-related protein Rah
	Modification date	20220513
	UniProtAcc	P0DI83, Q9BZG1

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
RAB34	GO:0006897	endocytosis	21873635	Process
RAB34	GO:0090385	phagosome-lysosome fusion	21873635	Process

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Spatial pattern events for RAB34

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
RAB34	Human	Prostate	rep_4	29925878	1.69e-09
RAB34	Human	Prostate	rep_7	29925878	1.73e-10
RAB34	Human	Intestine	rep_colon2	34417225	8.12e-16
RAB34	Human	Intestine	rep_colon3	34417225	1.24e-07
RAB34	Human	Liver	rep_liver1	34417225	5.20e-12
RAB34	Human	Intestine	A2	33406409	3.85e-15
RAB34	Human	Intestine	A4	33406409	1.09e-10
RAB34	Human	Uterus	rep_2	34857954	4.63e-15
RAB34	Human	Uterus	rep_3	34857954	1.66e-15
RAB34	Human	Breast	C6	34650042	9.99e-09
RAB34	Human	Breast	F2	34650042	3.56e-06
RAB34	Human	Breast	H2	34650042	9.30e-07
RAB34	Human	Breast	1142243F	34493872	4.13e-09
RAB34	Human	Breast	1160920F	34493872	1.48e-15
RAB34	Human	Heart	w6_s3	31835037	3.41e-04
RAB34	Human	Heart	w6_s4	31835037	2.49e-05

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon2_H&E
Intestine_rep_colon3_H&E
Liver_rep_liver1_H&E
Intestine_A2_H&E
Intestine_A4_H&E
Uterus_rep_2_H&E
Uterus_rep_3_H&E
Breast_C6_H&E
Breast_F2_H&E
Breast_H2_H&E
Breast_1142243F_H&E
Breast_1160920F_H&E

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Spatial pattern pathway has RAB34 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
RAB34	GOBP_Endocytosis	Human	Brain	rep_1	7.4e-34
RAB34	GOBP_Phagocytosis	Human	Brain	rep_1	3.1e-16
RAB34	GOBP_Positive_Regulation_Of_Signaling	Human	Brain	rep_1	6.4e-05
RAB34	GOBP_Endocytosis	Human	Liver	rep_1	1.5e-73
RAB34	GOBP_Phagocytosis	Human	Liver	rep_1	3.2e-72
RAB34	GOBP_Positive_Regulation_Of_Signaling	Human	Liver	rep_1	2.9e-73
RAB34	GOBP_Phagocytosis	Human	Intestine	rep_colon4	7.4e-22
RAB34	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	rep_colon4	2.0e-10
RAB34	GOBP_Cell_Projection_Organization	Human	Intestine	A3	1.1e-09
RAB34	GOBP_Cellular_Macromolecule_Localization	Human	Intestine	A3	1.7e-09
RAB34	GOBP_Endocytosis	Human	Intestine	A3	9.3e-10
RAB34	GOBP_Establishment_Of_Protein_Localization	Human	Intestine	A3	5.0e-10
RAB34	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Intestine	A3	7.6e-11
RAB34	GOBP_Golgi_To_Plasma_Membrane_Protein_Transport	Human	Intestine	A3	1.2e-12
RAB34	GOBP_Golgi_To_Plasma_Membrane_Transport	Human	Intestine	A3	2.8e-15
RAB34	GOBP_Golgi_Vesicle_Transport	Human	Intestine	A3	9.2e-10
RAB34	GOBP_Membrane_Fusion	Human	Intestine	A3	3.2e-07
RAB34	GOBP_Membrane_Organization	Human	Intestine	A3	2.7e-18
RAB34	GOBP_Organelle_Fusion	Human	Intestine	A3	9.7e-08
RAB34	GOBP_Organelle_Localization	Human	Intestine	A3	5.1e-12
RAB34	GOBP_Organelle_Membrane_Fusion	Human	Intestine	A3	2.4e-12
RAB34	GOBP_Phagocytosis	Human	Intestine	A3	2.4e-07
RAB34	GOBP_Phagosome_Lysosome_Fusion	Human	Intestine	A3	9.2e-07
RAB34	GOBP_Positive_Regulation_Of_Signaling	Human	Intestine	A3	3.3e-14
RAB34	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Intestine	A3	1.9e-10
RAB34	GOBP_Protein_Localization_To_Cell_Periphery	Human	Intestine	A3	4.6e-14
RAB34	GOBP_Protein_Localization_To_Plasma_Membrane	Human	Intestine	A3	4.0e-10
RAB34	GOBP_Vesicle_Mediated_Transport_To_The_Plasma_Membrane	Human	Intestine	A3	4.6e-07
RAB34	GOBP_Vesicle_Organization	Human	Intestine	A3	3.0e-15
RAB34	GOBP_Antigen_Processing_And_Presentation	Human	Intestine	A8	1.7e-13
RAB34	GOBP_Establishment_Of_Protein_Localization_To_Plasma_Membrane	Human	Intestine	A8	2.1e-18
RAB34	GOBP_Lytic_Vacuole_Organization	Human	Intestine	A8	2.3e-16
RAB34	GOBP_Vacuole_Organization	Human	Intestine	A8	2.4e-07
RAB34	GOBP_Phagosome_Lysosome_Fusion	Human	Uterus	rep_25	8.4e-10
RAB34	GOBP_Golgi_To_Plasma_Membrane_Protein_Transport	Human	Uterus	rep_26	3.0e-09
RAB34	GOBP_Golgi_To_Plasma_Membrane_Transport	Human	Uterus	rep_26	2.7e-08
RAB34	GOBP_Golgi_Vesicle_Transport	Human	Uterus	rep_26	3.4e-14
RAB34	GOBP_Lytic_Vacuole_Organization	Human	Uterus	rep_26	2.4e-06
RAB34	GOBP_Organelle_Membrane_Fusion	Human	Uterus	rep_26	5.5e-06
RAB34	GOBP_Phagosome_Maturation	Human	Uterus	rep_26	1.5e-10
RAB34	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Uterus	rep_26	4.4e-08
RAB34	GOBP_Vacuole_Organization	Human	Uterus	rep_26	3.0e-12
RAB34	GOBP_Establishment_Of_Protein_Localization_To_Plasma_Membrane	Human	Uterus	rep_29	3.3e-06
RAB34	GOBP_Cell_Projection_Organization	Human	Breast	rep_1	1.8e-20
RAB34	GOBP_Cellular_Macromolecule_Localization	Human	Breast	rep_1	3.7e-09
RAB34	GOBP_Establishment_Of_Protein_Localization	Human	Breast	rep_1	7.2e-05
RAB34	GOBP_Lytic_Vacuole_Organization	Human	Breast	rep_1	1.4e-06
RAB34	GOBP_Membrane_Fusion	Human	Breast	rep_1	9.3e-62
RAB34	GOBP_Organelle_Fusion	Human	Breast	rep_1	1.0e-07
RAB34	GOBP_Organelle_Localization	Human	Breast	rep_1	1.8e-08
RAB34	GOBP_Organelle_Membrane_Fusion	Human	Breast	rep_1	1.3e-79
RAB34	GOBP_Phagosome_Maturation	Human	Breast	rep_1	1.6e-92
RAB34	GOBP_Protein_Localization_To_Cell_Periphery	Human	Breast	rep_1	7.2e-19
RAB34	GOBP_Protein_Localization_To_Plasma_Membrane	Human	Breast	rep_1	1.9e-28
RAB34	GOBP_Vacuole_Organization	Human	Breast	rep_1	6.9e-10
RAB34	GOBP_Vesicle_Organization	Human	Breast	rep_1	8.3e-15
RAB34	GOBP_Phagolysosome_Assembly	Human	Breast	rep_5	1.2e-04
RAB34	GOBP_Positive_Regulation_Of_Signaling	Human	Breast	rep_5	1.3e-06
RAB34	GOBP_Post_Golgi_Vesicle_Mediated_Transport	Human	Breast	rep_5	8.2e-04
RAB34	GOBP_Establishment_Of_Protein_Localization_To_Membrane	Human	Breast	rep_6	3.8e-07
RAB34	GOBP_Establishment_Of_Protein_Localization_To_Plasma_Membrane	Human	Breast	rep_6	2.4e-04
RAB34	GOBP_Golgi_To_Plasma_Membrane_Protein_Transport	Human	Breast	rep_6	2.6e-10
RAB34	GOBP_Golgi_To_Plasma_Membrane_Transport	Human	Breast	rep_6	1.2e-09
RAB34	GOBP_Golgi_Vesicle_Transport	Human	Breast	rep_6	2.0e-08
RAB34	GOBP_Organelle_Assembly	Human	Breast	rep_6	2.3e-07
RAB34	GOBP_Phagosome_Lysosome_Fusion	Human	Breast	rep_6	2.2e-10
RAB34	GOBP_Positive_Regulation_Of_Smoothened_Signaling_Pathway	Human	Breast	rep_6	9.9e-12
RAB34	GOBP_Regulation_Of_Smoothened_Signaling_Pathway	Human	Breast	rep_6	3.5e-04
RAB34	GOBP_Smoothened_Signaling_Pathway	Human	Breast	rep_6	1.8e-04
RAB34	GOBP_Vesicle_Mediated_Transport_To_The_Plasma_Membrane	Human	Breast	rep_6	2.0e-08
RAB34	GOBP_Membrane_Fusion	Human	Skin	P5_rep1	3.5e-12
RAB34	GOBP_Organelle_Fusion	Human	Skin	P5_rep1	3.3e-08
RAB34	GOBP_Organelle_Localization	Human	Skin	P5_rep1	2.1e-13
RAB34	GOBP_Protein_Localization_To_Cell_Periphery	Human	Skin	P5_rep1	2.4e-09
RAB34	GOBP_Vesicle_Organization	Human	Skin	P5_rep1	2.3e-09
RAB34	GOBP_Golgi_To_Plasma_Membrane_Protein_Transport	Human	Skin	P5_rep3	6.2e-09
RAB34	GOBP_Phagosome_Lysosome_Fusion	Human	Skin	P10_rep1	5.5e-08

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RAB34 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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RAB34 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for RAB34 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for RAB34

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for RAB34

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source