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Spatial pattern gene: GRWD1 (spascer ID:83743) |
Gene summary for GRWD1 |
 Gene summary |
| Gene information | |
| Species | Human | Gene symbol | GRWD1 | Gene ID | 83743 |
| Gene name | glutamate rich WD repeat containing 1 |
| Synonyms | CDW4|GRWD|RRB1|WDR28 |
| Cytomap | 19q13.33 |
| Type of gene | protein-coding |
| Description | glutamate-rich WD repeat-containing protein 1CUL4- and DDB1-associated WDR protein 4WD repeat domain 28glutamate rich WD repeat protein GRWDregulator of ribosome biogenesis 1 homolog |
| Modification date | 20220513 |
| UniProtAcc | Q9BQ67 |
| Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA). |
| Gene | GO ID | GO term | PubMed ID | Category |
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Spatial pattern events for GRWD1 |
| spatial pattern gene list. |
| Gene symbol | Species | Tissue | Replication | PMID | Adj p-value |
| GRWD1 | Human | Intestine | rep_colon1 | 34417225 | 1.95e-15 |
| GRWD1 | Human | Intestine | rep_colon2 | 34417225 | 8.12e-16 |
| GRWD1 | Human | Intestine | rep_colon4 | 34417225 | 1.14e-15 |
| GRWD1 | Human | Liver | rep_liver1 | 34417225 | 1.08e-15 |
| GRWD1 | Human | Liver | rep_liver2 | 34417225 | 6.98e-16 |
| GRWD1 | Human | Intestine | A2 | 33406409 | 7.97e-10 |
| GRWD1 | Human | Uterus | rep_3 | 34857954 | 1.43e-07 |
| spatial pattern gene map.(click to enlarge the image in a new window) |
| H&E staining (if available) | Singel gene map |
Intestine_rep_colon1_H&E  |  |
Intestine_rep_colon2_H&E  |  |
Intestine_rep_colon4_H&E  |  |
Liver_rep_liver1_H&E  |  |
Liver_rep_liver2_H&E  |  |
Intestine_A2_H&E  |  |
Uterus_rep_3_H&E  |  |
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Spatial pattern pathway has GRWD1 envolved |
| Symbol | Pathway | Species | Tissue type | Replication | P-value |
| GRWD1 | GOBP_Cellular_Component_Disassembly | Human | Intestine | A3 | 1.0e-14 |
| GRWD1 | GOBP_Chromatin_Assembly_Or_Disassembly | Human | Intestine | A3 | 1.7e-09 |
| GRWD1 | GOBP_Chromatin_Disassembly | Human | Intestine | A3 | 4.7e-08 |
| GRWD1 | GOBP_Chromatin_Organization | Human | Intestine | A3 | 3.2e-11 |
| GRWD1 | GOBP_Chromosome_Organization | Human | Intestine | A3 | 2.5e-13 |
| GRWD1 | GOBP_Dna_Conformation_Change | Human | Intestine | A3 | 9.8e-12 |
| GRWD1 | GOBP_Dna_Packaging | Human | Intestine | A3 | 6.2e-08 |
| GRWD1 | GOBP_Dna_Replication | Human | Intestine | A3 | 2.5e-08 |
| GRWD1 | GOBP_Nucleosome_Assembly | Human | Intestine | A3 | 1.1e-07 |
| GRWD1 | GOBP_Nucleosome_Organization | Human | Intestine | A3 | 5.8e-10 |
| GRWD1 | GOBP_Protein_Dna_Complex_Subunit_Organization | Human | Intestine | A3 | 5.3e-07 |
| GRWD1 | GOBP_Protein_Dna_Complex_Disassembly | Human | Intestine | A8 | 5.8e-10 |
| GRWD1 | GOBP_Chromatin_Organization | Human | Uterus | rep_1 | 1.9e-06 |
| GRWD1 | GOBP_Dna_Packaging | Human | Uterus | rep_25 | 9.6e-06 |
| GRWD1 | GOBP_Nucleosome_Assembly | Human | Uterus | rep_25 | 6.0e-08 |
| GRWD1 | GOBP_Cellular_Component_Disassembly | Human | Uterus | rep_26 | 2.7e-06 |
| GRWD1 | GOBP_Chromatin_Assembly_Or_Disassembly | Human | Uterus | rep_26 | 4.8e-09 |
| GRWD1 | GOBP_Chromosome_Organization | Human | Uterus | rep_26 | 1.2e-09 |
| GRWD1 | GOBP_Dna_Conformation_Change | Human | Uterus | rep_26 | 1.2e-14 |
| GRWD1 | GOBP_Dna_Replication | Human | Uterus | rep_26 | 1.5e-09 |
| GRWD1 | GOBP_Nucleosome_Organization | Human | Uterus | rep_26 | 1.6e-09 |
| GRWD1 | GOBP_Protein_Dna_Complex_Subunit_Organization | Human | Uterus | rep_26 | 1.7e-08 |
| GRWD1 | GOBP_Cellular_Component_Disassembly | Human | Breast | rep_5 | 2.0e-06 |
| GRWD1 | GOBP_Chromatin_Assembly_Or_Disassembly | Human | Breast | rep_6 | 8.1e-05 |
| GRWD1 | GOBP_Chromatin_Disassembly | Human | Breast | rep_6 | 2.9e-07 |
| GRWD1 | GOBP_Chromatin_Organization | Human | Breast | rep_6 | 4.3e-07 |
| GRWD1 | GOBP_Chromosome_Organization | Human | Breast | rep_6 | 1.1e-06 |
| GRWD1 | GOBP_Dna_Conformation_Change | Human | Breast | rep_6 | 1.4e-05 |
| GRWD1 | GOBP_Dna_Packaging | Human | Breast | rep_6 | 1.9e-04 |
| GRWD1 | GOBP_Dna_Replication | Human | Breast | rep_6 | 3.5e-07 |
| GRWD1 | GOBP_Nucleosome_Assembly | Human | Breast | rep_6 | 6.7e-06 |
| GRWD1 | GOBP_Nucleosome_Organization | Human | Breast | rep_6 | 3.8e-06 |
| GRWD1 | GOBP_Protein_Containing_Complex_Disassembly | Human | Breast | rep_6 | 1.0e-13 |
| GRWD1 | GOBP_Protein_Dna_Complex_Disassembly | Human | Breast | rep_6 | 1.3e-14 |
| GRWD1 | GOBP_Protein_Dna_Complex_Subunit_Organization | Human | Breast | rep_6 | 1.9e-07 |
| GRWD1 | GOBP_Chromatin_Disassembly | Human | Skin | P2_rep2 | 4.5e-12 |
| GRWD1 | GOBP_Dna_Conformation_Change | Human | Skin | P5_rep1 | 1.8e-15 |
| GRWD1 | GOBP_Nucleosome_Assembly | Human | Skin | P10_rep2 | 1.5e-18 |
| GRWD1 | GOBP_Nucleosome_Organization | Human | Skin | P10_rep2 | 5.3e-12 |
| GRWD1 | GOBP_Cellular_Component_Disassembly | Human | Lung | rep_2 | 5.6e-07 |
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GRWD1 function as liang/receptor in single cell data |
| Tissue | Source | SourceCell | Target | TargetCell | PMID | Group |
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GRWD1 function as liang/receptor across spatial transcriptomics tissue |
| Interactions using deconvoluted spatial data. |
| Ligand | Receptor | LR pair | Tissue | Replication |
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Transcription factor for GRWD1 envolved |
| Transcription factor analysis using single cell data. |
| TF | Tissue | Group | Cell types | Target genes | Rss score |
| Motif information. |
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Related Drugs for GRWD1 |
| Approved drugs targeting this gene. (DrugBank Version 5.1.9 2022-01-04) |
| Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for GRWD1 |
| Diseases associated with this gene. (DisGeNet 7.0) |
| Gene | Disease ID | Disease name | Pubmeds | Source |
| GRWD1 | C0152013 | Adenocarcinoma of lung (disorder) | 1 | CTD_human |
