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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: SLC25A18 (spascer ID:83733)

Gene summary for SLC25A18

Gene summary

Gene information
	Species	Human
	Gene symbol	SLC25A18
	Gene ID	83733
	Gene name	solute carrier family 25 member 18
	Synonyms	GC2
	Cytomap	22q11.21
	Type of gene	protein-coding
	Description	mitochondrial glutamate carrier 2glutamate/H(+) symporter 2solute carrier family 25 (glutamate carrier), member 18solute carrier family 25 (mitochondrial carrier), member 18
	Modification date	20220513
	UniProtAcc	Q9H1K4

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
SLC25A18	GO:0005313	L-glutamate transmembrane transporter activity	21873635	Function
SLC25A18	GO:0006810	transport	21873635	Process
SLC25A18	GO:0015183	L-aspartate transmembrane transporter activity	21873635	Function
SLC25A18	GO:0015810	aspartate transmembrane transport	21873635	Process
SLC25A18	GO:0015813	L-glutamate transmembrane transport	21873635	Process
SLC25A18	GO:0022857	transmembrane transporter activity	21873635	Function
SLC25A18	GO:0043490	malate-aspartate shuttle	21873635	Process

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Spatial pattern events for SLC25A18

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
SLC25A18	Human	Liver	rep_liver1	34417225	1.08e-15
SLC25A18	Human	Liver	rep_liver2	34417225	6.98e-16

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E

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Spatial pattern pathway has SLC25A18 envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
SLC25A18	GOBP_Transmembrane_Transport	Human	Brain	rep_1	2.8e-23
SLC25A18	GOBP_Cellular_Respiration	Human	Bladder	rep_4	2.0e-15
SLC25A18	GOBP_Electron_Transport_Chain	Human	Bladder	rep_4	1.0e-20
SLC25A18	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Bladder	rep_4	1.5e-12
SLC25A18	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Bladder	rep_4	3.4e-12
SLC25A18	GOBP_Respiratory_Electron_Transport_Chain	Human	Bladder	rep_4	4.7e-21
SLC25A18	GOBP_Transmembrane_Transport	Human	Liver	rep_1	1.0e-70
SLC25A18	GOBP_Amino_Acid_Transport	Human	Intestine	A3	1.3e-07
SLC25A18	GOBP_Cellular_Respiration	Human	Intestine	A3	6.2e-15
SLC25A18	GOBP_Electron_Transport_Chain	Human	Intestine	A3	1.4e-19
SLC25A18	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Intestine	A3	2.5e-12
SLC25A18	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Intestine	A3	4.3e-14
SLC25A18	GOBP_Mitochondrial_Transmembrane_Transport	Human	Intestine	A3	3.6e-07
SLC25A18	GOBP_Mitochondrial_Transport	Human	Intestine	A3	9.8e-16
SLC25A18	GOBP_Respiratory_Electron_Transport_Chain	Human	Intestine	A3	7.5e-17
SLC25A18	GOBP_Transmembrane_Transport	Human	Intestine	A3	1.4e-10
SLC25A18	GOBP_Acidic_Amino_Acid_Transport	Human	Intestine	A8	6.2e-22
SLC25A18	GOBP_Amino_Acid_Transmembrane_Transport	Human	Intestine	A8	6.6e-18
SLC25A18	GOBP_Anion_Transmembrane_Transport	Human	Intestine	A8	1.2e-13
SLC25A18	GOBP_Aspartate_Transmembrane_Transport	Human	Intestine	A8	4.1e-07
SLC25A18	GOBP_C4_Dicarboxylate_Transport	Human	Intestine	A8	3.8e-11
SLC25A18	GOBP_Carboxylic_Acid_Transport	Human	Intestine	A8	4.8e-16
SLC25A18	GOBP_Dicarboxylic_Acid_Transport	Human	Intestine	A8	1.1e-15
SLC25A18	GOBP_Fatty_Acid_Transmembrane_Transport	Human	Intestine	A8	1.9e-17
SLC25A18	GOBP_Fatty_Acid_Transport	Human	Intestine	A8	3.0e-08
SLC25A18	GOBP_L_Alpha_Amino_Acid_Transmembrane_Transport	Human	Intestine	A8	1.6e-16
SLC25A18	GOBP_L_Amino_Acid_Transport	Human	Intestine	A8	2.6e-08
SLC25A18	GOBP_L_Aspartate_Transmembrane_Transport	Human	Intestine	A8	1.5e-10
SLC25A18	GOBP_L_Glutamate_Transmembrane_Transport	Human	Intestine	A8	2.3e-10
SLC25A18	GOBP_Lipid_Localization	Human	Intestine	A8	2.5e-15
SLC25A18	GOBP_Monocarboxylic_Acid_Transport	Human	Intestine	A8	7.2e-16
SLC25A18	GOBP_Organic_Acid_Transmembrane_Transport	Human	Intestine	A8	3.8e-16
SLC25A18	GOBP_Organic_Acid_Transport	Human	Intestine	A8	1.5e-15
SLC25A18	GOBP_Organic_Anion_Transport	Human	Intestine	A8	3.5e-15
SLC25A18	GOBP_Acidic_Amino_Acid_Transport	Human	Pancreas	PDAC-B-st1	2.9e-05
SLC25A18	GOBP_Amino_Acid_Transmembrane_Transport	Human	Pancreas	PDAC-B-st1	3.2e-07
SLC25A18	GOBP_Amino_Acid_Transport	Human	Pancreas	PDAC-B-st1	3.8e-07
SLC25A18	GOBP_Dicarboxylic_Acid_Transport	Human	Pancreas	PDAC-B-st1	4.8e-08
SLC25A18	GOBP_L_Alpha_Amino_Acid_Transmembrane_Transport	Human	Pancreas	PDAC-B-st1	1.4e-05
SLC25A18	GOBP_Acidic_Amino_Acid_Transport	Human	Uterus	rep_25	3.9e-07
SLC25A18	GOBP_Amino_Acid_Transport	Human	Uterus	rep_25	3.6e-06
SLC25A18	GOBP_Aspartate_Transmembrane_Transport	Human	Uterus	rep_25	1.4e-24
SLC25A18	GOBP_C4_Dicarboxylate_Transport	Human	Uterus	rep_25	2.8e-09
SLC25A18	GOBP_Dicarboxylic_Acid_Transport	Human	Uterus	rep_25	1.3e-06
SLC25A18	GOBP_L_Aspartate_Transmembrane_Transport	Human	Uterus	rep_25	1.3e-09
SLC25A18	GOBP_Carboxylic_Acid_Transport	Human	Uterus	rep_26	9.1e-08
SLC25A18	GOBP_Cellular_Respiration	Human	Uterus	rep_26	3.7e-07
SLC25A18	GOBP_Electron_Transport_Chain	Human	Uterus	rep_26	1.9e-08
SLC25A18	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Uterus	rep_26	7.2e-06
SLC25A18	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Uterus	rep_26	1.8e-06
SLC25A18	GOBP_L_Amino_Acid_Transport	Human	Uterus	rep_26	1.8e-11
SLC25A18	GOBP_L_Glutamate_Transmembrane_Transport	Human	Uterus	rep_26	1.7e-15
SLC25A18	GOBP_Lipid_Localization	Human	Uterus	rep_26	3.7e-10
SLC25A18	GOBP_Mitochondrial_Transmembrane_Transport	Human	Uterus	rep_26	8.3e-06
SLC25A18	GOBP_Respiratory_Electron_Transport_Chain	Human	Uterus	rep_26	2.1e-08
SLC25A18	GOBP_Amino_Acid_Transmembrane_Transport	Human	Breast	rep_1	3.4e-84
SLC25A18	GOBP_Aspartate_Transmembrane_Transport	Human	Breast	rep_1	9.1e-86
SLC25A18	GOBP_L_Alpha_Amino_Acid_Transmembrane_Transport	Human	Breast	rep_1	4.9e-08
SLC25A18	GOBP_L_Aspartate_Transmembrane_Transport	Human	Breast	rep_1	9.0e-27
SLC25A18	GOBP_Organic_Acid_Transmembrane_Transport	Human	Breast	rep_1	3.1e-21
SLC25A18	GOBP_Transmembrane_Transport	Human	Breast	rep_1	3.2e-56
SLC25A18	GOBP_Fatty_Acid_Transmembrane_Transport	Human	Breast	rep_4	2.0e-06
SLC25A18	GOBP_Acidic_Amino_Acid_Transport	Human	Breast	rep_5	2.0e-13
SLC25A18	GOBP_Amino_Acid_Transport	Human	Breast	rep_5	1.8e-19
SLC25A18	GOBP_Anion_Transmembrane_Transport	Human	Breast	rep_5	2.6e-06
SLC25A18	GOBP_C4_Dicarboxylate_Transport	Human	Breast	rep_5	2.0e-18
SLC25A18	GOBP_Carboxylic_Acid_Transport	Human	Breast	rep_5	5.4e-12
SLC25A18	GOBP_Dicarboxylic_Acid_Transport	Human	Breast	rep_5	2.9e-10
SLC25A18	GOBP_Electron_Transport_Chain	Human	Breast	rep_5	6.2e-04
SLC25A18	GOBP_L_Amino_Acid_Transport	Human	Breast	rep_5	3.8e-18
SLC25A18	GOBP_L_Glutamate_Transmembrane_Transport	Human	Breast	rep_5	7.3e-04
SLC25A18	GOBP_Lipid_Localization	Human	Breast	rep_5	1.4e-06
SLC25A18	GOBP_Organic_Anion_Transport	Human	Breast	rep_5	9.5e-10
SLC25A18	GOBP_Respiratory_Electron_Transport_Chain	Human	Breast	rep_5	3.1e-04
SLC25A18	GOBP_Cellular_Respiration	Human	Breast	rep_6	2.2e-06
SLC25A18	GOBP_Energy_Derivation_By_Oxidation_Of_Organic_Compounds	Human	Breast	rep_6	5.2e-08
SLC25A18	GOBP_Fatty_Acid_Transport	Human	Breast	rep_6	3.1e-06
SLC25A18	GOBP_Generation_Of_Precursor_Metabolites_And_Energy	Human	Breast	rep_6	7.1e-09
SLC25A18	GOBP_Mitochondrial_Transmembrane_Transport	Human	Breast	rep_6	2.7e-08
SLC25A18	GOBP_Mitochondrial_Transport	Human	Breast	rep_6	6.5e-10
SLC25A18	GOBP_Monocarboxylic_Acid_Transport	Human	Breast	rep_6	1.9e-12
SLC25A18	GOBP_Organic_Acid_Transport	Human	Breast	rep_6	9.3e-09
SLC25A18	GOBP_Fatty_Acid_Transport	Human	Skin	P2_rep2	1.4e-08
SLC25A18	GOBP_Carboxylic_Acid_Transport	Human	Skin	P5_rep1	3.2e-08
SLC25A18	GOBP_L_Amino_Acid_Transport	Human	Skin	P5_rep1	8.3e-08
SLC25A18	GOBP_Organic_Acid_Transmembrane_Transport	Human	Skin	P5_rep2	4.4e-08
SLC25A18	GOBP_C4_Dicarboxylate_Transport	Human	Skin	P10_rep2	2.1e-08
SLC25A18	GOBP_L_Aspartate_Transmembrane_Transport	Human	Skin	P10_rep2	1.6e-31
SLC25A18	GOBP_C4_Dicarboxylate_Transport	Human	Lung	rep_1	5.8e-09
SLC25A18	GOBP_Dicarboxylic_Acid_Transport	Human	Lung	rep_1	8.0e-07
SLC25A18	GOBP_L_Aspartate_Transmembrane_Transport	Human	Lung	rep_1	2.0e-07

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SLC25A18 function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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SLC25A18 function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for SLC25A18 envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for SLC25A18

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for SLC25A18

Diseases associated with this gene.
(DisGeNet 7.0)

Gene

Disease ID

Disease name

Pubmeds

Source