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	Gene summary
	Spatial pattern genes
	Spatial pattern pathway
	Cell cell interactions using single cell data
	Cell-cell/spot-spot interactions using spatial data
	Transcription factors events
	Related drugs with this gene
	Related diseases with this gene

Spatial pattern gene: CAD (spascer ID:790)

Gene summary for CAD

Gene summary

Gene information
	Species	Human
	Gene symbol	CAD
	Gene ID	790
	Gene name	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
	Synonyms	CDG1Z\|DEE50\|EIEE50\|GATD4
	Cytomap	2p23.3
	Type of gene	protein-coding
	Description	CAD proteinCAD trifunctional proteinmultifunctional protein CAD
	Modification date	20220513
	UniProtAcc	P27708

Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).

Gene	GO ID	GO term	PubMed ID	Category
CAD	GO:0004070	aspartate carbamoyltransferase activity	21873635	Function
CAD	GO:0004151	dihydroorotase activity	21873635	Function
CAD	GO:0005737	cytoplasm	21873635	Component
CAD	GO:0005829	cytosol	21873635	Component
CAD	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process	21873635	Process
CAD	GO:0006228	UTP biosynthetic process	21873635	Process
CAD	GO:0006541	glutamine metabolic process	21873635	Process
CAD	GO:0006807	nitrogen compound metabolic process	21873635	Process
CAD	GO:0019240	citrulline biosynthetic process	21873635	Process

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Spatial pattern events for CAD

spatial pattern gene list.

Gene symbol	Species	Tissue	Replication	PMID	Adj p-value
CAD	Human	Intestine	rep_colon1	34417225	1.95e-15
CAD	Human	Intestine	rep_colon4	34417225	1.14e-15
CAD	Human	Liver	rep_liver1	34417225	1.08e-15
CAD	Human	Liver	rep_liver2	34417225	6.98e-16
CAD	Human	Intestine	A2	33406409	5.84e-09
CAD	Human	Uterus	rep_1	34857954	3.72e-07
CAD	Human	Breast	1160920F	34493872	2.68e-15
CAD	Human	Breast	CID44971	34493872	1.76e-15

spatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)	Singel gene map
Intestine_rep_colon1_H&E
Intestine_rep_colon4_H&E
Liver_rep_liver1_H&E
Liver_rep_liver2_H&E
Intestine_A2_H&E
Uterus_rep_1_H&E
Breast_1160920F_H&E
Breast_CID44971_H&E

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Spatial pattern pathway has CAD envolved

Symbol	Pathway	Species	Tissue type	Replication	P-value
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Brain	rep_1	6.9e-125
CAD	GOBP_Circulatory_System_Development	Human	Brain	rep_4	4.1e-17
CAD	GOBP_Response_To_Endogenous_Stimulus	Human	Brain	rep_10	2.8e-23
CAD	GOBP_Response_To_Hormone	Human	Brain	rep_10	2.8e-23
CAD	GOBP_Response_To_Lipid	Human	Brain	rep_10	2.8e-23
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Brain	rep_10	5.3e-26
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Brain	rep_11	2.5e-12
CAD	GOBP_Response_To_Ketone	Human	Brain	rep_11	2.5e-12
CAD	GOBP_Body_Fluid_Secretion	Human	Brain	st	1.0e-08
CAD	GOBP_Citrulline_Biosynthetic_Process	Human	Brain	st	1.7e-24
CAD	GOBP_Mammary_Gland_Development	Human	Brain	st	2.7e-09
CAD	GOBP_Circulatory_System_Development	Human	Bladder	rep_2	1.0e-16
CAD	GOBP_Response_To_Corticosteroid	Human	Bladder	rep_2	3.3e-18
CAD	GOBP_Response_To_Growth_Factor	Human	Bladder	rep_2	1.2e-08
CAD	GOBP_Response_To_Peptide	Human	Bladder	rep_2	2.3e-11
CAD	GOBP_Response_To_Peptide_Hormone	Human	Bladder	rep_2	2.9e-13
CAD	GOBP_Response_To_Purine_Containing_Compound	Human	Bladder	rep_2	5.7e-20
CAD	GOBP_Body_Fluid_Secretion	Human	Bladder	rep_4	2.0e-07
CAD	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Bladder	rep_4	3.0e-06
CAD	GOBP_Lactation	Human	Bladder	rep_4	4.3e-10
CAD	GOBP_Mammary_Gland_Development	Human	Bladder	rep_4	1.4e-05
CAD	GOBP_Nucleoside_Phosphate_Biosynthetic_Process	Human	Bladder	rep_4	1.4e-09
CAD	GOBP_Nucleoside_Triphosphate_Biosynthetic_Process	Human	Bladder	rep_4	1.9e-13
CAD	GOBP_Nucleoside_Triphosphate_Metabolic_Process	Human	Bladder	rep_4	5.1e-14
CAD	GOBP_Organophosphate_Biosynthetic_Process	Human	Bladder	rep_4	3.2e-09
CAD	GOBP_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Bladder	rep_4	3.9e-12
CAD	GOBP_Ribonucleoside_Triphosphate_Metabolic_Process	Human	Bladder	rep_4	2.7e-13
CAD	GOBP_Ribose_Phosphate_Biosynthetic_Process	Human	Bladder	rep_4	1.9e-16
CAD	GOBP_Circulatory_System_Development	Human	Liver	rep_1	6.0e-76
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Liver	rep_1	3.1e-62
CAD	GOBP_Response_To_Endogenous_Stimulus	Human	Liver	rep_1	3.0e-55
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Liver	rep_1	1.7e-73
CAD	GOBP_Response_To_Hormone	Human	Liver	rep_1	3.0e-55
CAD	GOBP_Response_To_Ketone	Human	Liver	rep_1	1.7e-73
CAD	GOBP_Response_To_Lipid	Human	Liver	rep_1	3.0e-55
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Liver	rep_1	1.5e-74
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	rep_colon2	3.9e-21
CAD	GOBP_Circulatory_System_Development	Human	Intestine	rep_colon4	1.9e-09
CAD	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	rep_liver2	3.7e-39
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	rep_liver2	8.9e-16
CAD	GOBP_Response_To_Hormone	Human	Intestine	rep_liver2	3.7e-39
CAD	GOBP_Response_To_Ketone	Human	Intestine	rep_liver2	8.9e-16
CAD	GOBP_Response_To_Lipid	Human	Intestine	rep_liver2	3.7e-39
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	rep_liver2	3.3e-10
CAD	GOBP_Response_To_Cortisol	Human	Intestine	A1	2.8e-17
CAD	GOBP_Body_Fluid_Secretion	Human	Intestine	A3	6.0e-09
CAD	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Intestine	A3	1.8e-09
CAD	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Intestine	A3	3.3e-11
CAD	GOBP_Circulatory_System_Development	Human	Intestine	A3	5.9e-08
CAD	GOBP_Gland_Development	Human	Intestine	A3	2.3e-14
CAD	GOBP_Heart_Development	Human	Intestine	A3	3.2e-07
CAD	GOBP_Hepaticobiliary_System_Development	Human	Intestine	A3	1.6e-07
CAD	GOBP_Lactation	Human	Intestine	A3	5.5e-16
CAD	GOBP_Mammary_Gland_Development	Human	Intestine	A3	3.5e-14
CAD	GOBP_Multi_Multicellular_Organism_Process	Human	Intestine	A3	5.6e-10
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Intestine	A3	9.9e-10
CAD	GOBP_Nucleoside_Monophosphate_Biosynthetic_Process	Human	Intestine	A3	3.8e-07
CAD	GOBP_Nucleoside_Monophosphate_Metabolic_Process	Human	Intestine	A3	1.3e-12
CAD	GOBP_Nucleoside_Phosphate_Biosynthetic_Process	Human	Intestine	A3	1.6e-10
CAD	GOBP_Nucleoside_Triphosphate_Biosynthetic_Process	Human	Intestine	A3	1.4e-07
CAD	GOBP_Organophosphate_Biosynthetic_Process	Human	Intestine	A3	2.2e-07
CAD	GOBP_Organophosphate_Metabolic_Process	Human	Intestine	A3	4.4e-13
CAD	GOBP_Peptidyl_Amino_Acid_Modification	Human	Intestine	A3	2.7e-09
CAD	GOBP_Protein_Autophosphorylation	Human	Intestine	A3	8.1e-13
CAD	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Intestine	A3	9.4e-08
CAD	GOBP_Regeneration	Human	Intestine	A3	5.3e-11
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Intestine	A3	2.9e-09
CAD	GOBP_Reproduction	Human	Intestine	A3	4.6e-19
CAD	GOBP_Response_To_Alcohol	Human	Intestine	A3	3.7e-08
CAD	GOBP_Response_To_Alkaloid	Human	Intestine	A3	2.7e-11
CAD	GOBP_Response_To_Amine	Human	Intestine	A3	1.7e-13
CAD	GOBP_Response_To_Endogenous_Stimulus	Human	Intestine	A3	5.2e-09
CAD	GOBP_Response_To_Insulin	Human	Intestine	A3	2.2e-15
CAD	GOBP_Response_To_Lipid	Human	Intestine	A3	1.7e-09
CAD	GOBP_Response_To_Organic_Cyclic_Compound	Human	Intestine	A3	3.2e-15
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Intestine	A3	8.2e-08
CAD	GOBP_Response_To_Steroid_Hormone	Human	Intestine	A3	2.1e-13
CAD	GOBP_Ribonucleoside_Monophosphate_Biosynthetic_Process	Human	Intestine	A3	6.3e-09
CAD	GOBP_Ribonucleoside_Monophosphate_Metabolic_Process	Human	Intestine	A3	1.0e-14
CAD	GOBP_Ribose_Phosphate_Biosynthetic_Process	Human	Intestine	A3	7.6e-08
CAD	GOBP_Secretion	Human	Intestine	A3	1.8e-13
CAD	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Intestine	A8	7.0e-13
CAD	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Intestine	A8	5.3e-13
CAD	GOBP_Citrulline_Biosynthetic_Process	Human	Intestine	A8	6.0e-11
CAD	GOBP_De_Novo_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Intestine	A8	5.0e-10
CAD	GOBP_Glutamine_Family_Amino_Acid_Metabolic_Process	Human	Intestine	A8	4.2e-08
CAD	GOBP_Glutamine_Metabolic_Process	Human	Intestine	A8	6.1e-09
CAD	GOBP_Glycosyl_Compound_Biosynthetic_Process	Human	Intestine	A8	1.4e-07
CAD	GOBP_Glycosyl_Compound_Metabolic_Process	Human	Intestine	A8	2.8e-08
CAD	GOBP_Nucleobase_Biosynthetic_Process	Human	Intestine	A8	2.2e-13
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	2.6e-08
CAD	GOBP_Nucleoside_Metabolic_Process	Human	Intestine	A8	4.8e-09
CAD	GOBP_Organic_Acid_Biosynthetic_Process	Human	Intestine	A8	2.1e-08
CAD	GOBP_Organic_Acid_Metabolic_Process	Human	Intestine	A8	2.5e-18
CAD	GOBP_Peptidyl_Threonine_Modification	Human	Intestine	A8	1.2e-08
CAD	GOBP_Pyrimidine_Containing_Compound_Biosynthetic_Process	Human	Intestine	A8	4.1e-08
CAD	GOBP_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Intestine	A8	9.7e-13
CAD	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Intestine	A8	1.1e-11
CAD	GOBP_Pyrimidine_Nucleoside_Monophosphate_Biosynthetic_Process	Human	Intestine	A8	2.7e-10
CAD	GOBP_Pyrimidine_Ribonucleoside_Monophosphate_Metabolic_Process	Human	Intestine	A8	8.5e-17
CAD	GOBP_Pyrimidine_Ribonucleotide_Biosynthetic_Process	Human	Intestine	A8	5.2e-10
CAD	GOBP_Pyrimidine_Ribonucleotide_Metabolic_Process	Human	Intestine	A8	2.4e-11
CAD	GOBP_Response_To_Corticosteroid	Human	Intestine	A8	4.4e-19
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Intestine	A8	2.1e-23
CAD	GOBP_Response_To_Hormone	Human	Intestine	A8	2.3e-13
CAD	GOBP_Response_To_Ketone	Human	Intestine	A8	1.1e-27
CAD	GOBP_Response_To_Nitrogen_Compound	Human	Intestine	A8	1.3e-12
CAD	GOBP_Response_To_Peptide	Human	Intestine	A8	2.0e-09
CAD	GOBP_Response_To_Peptide_Hormone	Human	Intestine	A8	3.4e-09
CAD	GOBP_Response_To_Purine_Containing_Compound	Human	Intestine	A8	1.7e-20
CAD	GOBP_Response_To_Starvation	Human	Intestine	A8	6.6e-17
CAD	GOBP_Response_To_Testosterone	Human	Intestine	A8	4.5e-07
CAD	GOBP_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Intestine	A8	9.5e-08
CAD	GOBP_Small_Molecule_Biosynthetic_Process	Human	Intestine	A8	1.0e-14
CAD	GOBP_Small_Molecule_Metabolic_Process	Human	Intestine	A8	2.1e-15
CAD	GOBP_Ump_Biosynthetic_Process	Human	Intestine	A8	2.3e-14
CAD	GOBP_Animal_Organ_Regeneration	Human	Pancreas	PDAC-B-st1	2.9e-05
CAD	GOBP_Regeneration	Human	Pancreas	PDAC-B-st1	6.7e-06
CAD	GOBP_Response_To_Starvation	Human	Pancreas	PDAC-B-st1	9.3e-06
CAD	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Pancreas	PDAC-A-st2	9.6e-05
CAD	GOBP_Pyrimidine_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Pancreas	PDAC-A-st2	1.2e-05
CAD	GOBP_Pyrimidine_Ribonucleoside_Triphosphate_Metabolic_Process	Human	Pancreas	PDAC-A-st2	1.8e-06
CAD	GOBP_Response_To_Cortisol	Human	Pancreas	PDAC-A-st2	7.8e-06
CAD	GOBP_Response_To_Caffeine	Human	Pancreas	PDAC-A-st3	4.1e-05
CAD	GOBP_Peptidyl_Threonine_Modification	Human	Uterus	rep_1	7.0e-07
CAD	GOBP_Citrulline_Metabolic_Process	Human	Uterus	rep_25	1.1e-07
CAD	GOBP_Glutamine_Metabolic_Process	Human	Uterus	rep_25	4.4e-06
CAD	GOBP_Pyrimidine_Ribonucleotide_Biosynthetic_Process	Human	Uterus	rep_25	6.1e-09
CAD	GOBP_Response_To_Cortisol	Human	Uterus	rep_25	3.5e-09
CAD	GOBP_Ribonucleoside_Monophosphate_Biosynthetic_Process	Human	Uterus	rep_25	3.3e-14
CAD	GOBP_Ump_Biosynthetic_Process	Human	Uterus	rep_25	1.2e-06
CAD	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	1.6e-06
CAD	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Uterus	rep_26	3.5e-11
CAD	GOBP_Citrulline_Biosynthetic_Process	Human	Uterus	rep_26	4.1e-06
CAD	GOBP_De_Novo_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Uterus	rep_26	3.0e-14
CAD	GOBP_Gland_Development	Human	Uterus	rep_26	1.6e-07
CAD	GOBP_Glutamine_Family_Amino_Acid_Metabolic_Process	Human	Uterus	rep_26	5.2e-08
CAD	GOBP_Glycosyl_Compound_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-12
CAD	GOBP_Nucleobase_Biosynthetic_Process	Human	Uterus	rep_26	1.8e-06
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-12
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Uterus	rep_26	2.4e-06
CAD	GOBP_Nucleobase_Metabolic_Process	Human	Uterus	rep_26	4.3e-08
CAD	GOBP_Nucleoside_Metabolic_Process	Human	Uterus	rep_26	7.6e-12
CAD	GOBP_Nucleoside_Monophosphate_Biosynthetic_Process	Human	Uterus	rep_26	7.8e-11
CAD	GOBP_Nucleoside_Monophosphate_Metabolic_Process	Human	Uterus	rep_26	4.7e-06
CAD	GOBP_Nucleoside_Phosphate_Biosynthetic_Process	Human	Uterus	rep_26	3.4e-15
CAD	GOBP_Nucleoside_Triphosphate_Biosynthetic_Process	Human	Uterus	rep_26	1.2e-09
CAD	GOBP_Nucleoside_Triphosphate_Metabolic_Process	Human	Uterus	rep_26	1.1e-08
CAD	GOBP_Organic_Acid_Biosynthetic_Process	Human	Uterus	rep_26	2.3e-06
CAD	GOBP_Organic_Acid_Metabolic_Process	Human	Uterus	rep_26	4.9e-06
CAD	GOBP_Organophosphate_Biosynthetic_Process	Human	Uterus	rep_26	8.0e-07
CAD	GOBP_Pyrimidine_Containing_Compound_Biosynthetic_Process	Human	Uterus	rep_26	3.2e-11
CAD	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Uterus	rep_26	2.8e-08
CAD	GOBP_Pyrimidine_Nucleoside_Triphosphate_Biosynthetic_Process	Human	Uterus	rep_26	3.2e-06
CAD	GOBP_Pyrimidine_Ribonucleoside_Monophosphate_Metabolic_Process	Human	Uterus	rep_26	1.5e-09
CAD	GOBP_Pyrimidine_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Uterus	rep_26	6.5e-06
CAD	GOBP_Pyrimidine_Ribonucleoside_Triphosphate_Metabolic_Process	Human	Uterus	rep_26	1.3e-16
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Uterus	rep_26	1.1e-14
CAD	GOBP_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
CAD	GOBP_Ribonucleoside_Triphosphate_Metabolic_Process	Human	Uterus	rep_26	9.8e-09
CAD	GOBP_Ribose_Phosphate_Biosynthetic_Process	Human	Uterus	rep_26	2.1e-08
CAD	GOBP_Small_Molecule_Biosynthetic_Process	Human	Uterus	rep_26	5.8e-09
CAD	GOBP_Utp_Metabolic_Process	Human	Uterus	rep_26	7.2e-08
CAD	GOBP_Multi_Multicellular_Organism_Process	Human	Uterus	rep_29	2.8e-06
CAD	GOBP_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Uterus	rep_29	5.1e-09
CAD	GOBP_Pyrimidine_Nucleoside_Monophosphate_Biosynthetic_Process	Human	Uterus	rep_29	6.3e-07
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Uterus	rep_29	1.7e-06
CAD	GOBP_Response_To_Corticosteroid	Human	Uterus	rep_29	4.7e-06
CAD	GOBP_Body_Fluid_Secretion	Human	Breast	rep_1	2.0e-108
CAD	GOBP_Carbohydrate_Derivative_Biosynthetic_Process	Human	Breast	rep_1	2.1e-06
CAD	GOBP_Circulatory_System_Development	Human	Breast	rep_1	3.8e-70
CAD	GOBP_Citrulline_Metabolic_Process	Human	Breast	rep_1	1.4e-38
CAD	GOBP_Gland_Development	Human	Breast	rep_1	2.0e-26
CAD	GOBP_Heart_Development	Human	Breast	rep_1	4.1e-08
CAD	GOBP_Lactation	Human	Breast	rep_1	2.2e-125
CAD	GOBP_Mammary_Gland_Development	Human	Breast	rep_1	2.7e-164
CAD	GOBP_Multi_Multicellular_Organism_Process	Human	Breast	rep_1	1.7e-22
CAD	GOBP_Nucleoside_Triphosphate_Biosynthetic_Process	Human	Breast	rep_1	9.3e-16
CAD	GOBP_Nucleoside_Triphosphate_Metabolic_Process	Human	Breast	rep_1	2.9e-11
CAD	GOBP_Organophosphate_Biosynthetic_Process	Human	Breast	rep_1	1.4e-07
CAD	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Breast	rep_1	8.4e-07
CAD	GOBP_Regeneration	Human	Breast	rep_1	2.9e-06
CAD	GOBP_Regulation_Of_Body_Fluid_Levels	Human	Breast	rep_1	3.7e-127
CAD	GOBP_Response_To_Alcohol	Human	Breast	rep_1	1.3e-11
CAD	GOBP_Response_To_Corticosteroid	Human	Breast	rep_1	1.5e-56
CAD	GOBP_Response_To_Growth_Factor	Human	Breast	rep_1	1.2e-13
CAD	GOBP_Response_To_Insulin	Human	Breast	rep_1	5.1e-04
CAD	GOBP_Response_To_Peptide_Hormone	Human	Breast	rep_1	2.0e-36
CAD	GOBP_Response_To_Purine_Containing_Compound	Human	Breast	rep_1	4.8e-85
CAD	GOBP_Ribonucleoside_Triphosphate_Biosynthetic_Process	Human	Breast	rep_1	5.8e-27
CAD	GOBP_Ribonucleoside_Triphosphate_Metabolic_Process	Human	Breast	rep_1	6.8e-12
CAD	GOBP_Ribose_Phosphate_Biosynthetic_Process	Human	Breast	rep_1	3.7e-07
CAD	GOBP_Secretion	Human	Breast	rep_1	9.7e-57
CAD	GOBP_Response_To_Cortisol	Human	Breast	rep_3	7.2e-16
CAD	GOBP_Organic_Acid_Biosynthetic_Process	Human	Breast	rep_5	3.5e-09
CAD	GOBP_Protein_Autophosphorylation	Human	Breast	rep_5	2.3e-14
CAD	GOBP_Pyrimidine_Nucleobase_Metabolic_Process	Human	Breast	rep_5	1.8e-05
CAD	GOBP_Pyrimidine_Nucleoside_Monophosphate_Metabolic_Process	Human	Breast	rep_5	1.0e-14
CAD	GOBP_Reproduction	Human	Breast	rep_5	8.1e-06
CAD	GOBP_Response_To_Endogenous_Stimulus	Human	Breast	rep_5	3.6e-09
CAD	GOBP_Response_To_Extracellular_Stimulus	Human	Breast	rep_5	2.9e-12
CAD	GOBP_Response_To_Hormone	Human	Breast	rep_5	2.9e-13
CAD	GOBP_Response_To_Ketone	Human	Breast	rep_5	3.5e-14
CAD	GOBP_Response_To_Lipid	Human	Breast	rep_5	1.6e-10
CAD	GOBP_Response_To_Nitrogen_Compound	Human	Breast	rep_5	1.1e-11
CAD	GOBP_Response_To_Organic_Cyclic_Compound	Human	Breast	rep_5	7.5e-14
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Breast	rep_5	4.2e-13
CAD	GOBP_Response_To_Peptide	Human	Breast	rep_5	1.2e-15
CAD	GOBP_Response_To_Starvation	Human	Breast	rep_5	6.9e-08
CAD	GOBP_Response_To_Steroid_Hormone	Human	Breast	rep_5	4.5e-13
CAD	GOBP_Response_To_Testosterone	Human	Breast	rep_5	1.5e-05
CAD	GOBP_Alpha_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.7e-08
CAD	GOBP_Animal_Organ_Regeneration	Human	Breast	rep_6	1.9e-10
CAD	GOBP_Carbohydrate_Derivative_Metabolic_Process	Human	Breast	rep_6	6.1e-07
CAD	GOBP_Cellular_Amino_Acid_Metabolic_Process	Human	Breast	rep_6	1.0e-10
CAD	GOBP_Glycosyl_Compound_Biosynthetic_Process	Human	Breast	rep_6	8.0e-08
CAD	GOBP_Glycosyl_Compound_Metabolic_Process	Human	Breast	rep_6	1.2e-07
CAD	GOBP_Hepaticobiliary_System_Development	Human	Breast	rep_6	1.5e-07
CAD	GOBP_Nucleobase_Biosynthetic_Process	Human	Breast	rep_6	2.5e-06
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	4.8e-04
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	1.7e-10
CAD	GOBP_Nucleobase_Metabolic_Process	Human	Breast	rep_6	2.2e-05
CAD	GOBP_Nucleoside_Metabolic_Process	Human	Breast	rep_6	8.1e-07
CAD	GOBP_Nucleoside_Monophosphate_Biosynthetic_Process	Human	Breast	rep_6	3.2e-16
CAD	GOBP_Nucleoside_Monophosphate_Metabolic_Process	Human	Breast	rep_6	3.6e-15
CAD	GOBP_Nucleoside_Phosphate_Biosynthetic_Process	Human	Breast	rep_6	6.2e-07
CAD	GOBP_Organic_Acid_Metabolic_Process	Human	Breast	rep_6	6.7e-05
CAD	GOBP_Organonitrogen_Compound_Biosynthetic_Process	Human	Breast	rep_6	1.2e-09
CAD	GOBP_Organophosphate_Metabolic_Process	Human	Breast	rep_6	1.0e-12
CAD	GOBP_Peptidyl_Amino_Acid_Modification	Human	Breast	rep_6	3.8e-05
CAD	GOBP_Pyrimidine_Containing_Compound_Biosynthetic_Process	Human	Breast	rep_6	5.6e-04
CAD	GOBP_Pyrimidine_Containing_Compound_Metabolic_Process	Human	Breast	rep_6	6.5e-06
CAD	GOBP_Pyrimidine_Nucleoside_Triphosphate_Metabolic_Process	Human	Breast	rep_6	3.1e-04
CAD	GOBP_Pyrimidine_Nucleotide_Metabolic_Process	Human	Breast	rep_6	2.0e-08
CAD	GOBP_Response_To_Alkaloid	Human	Breast	rep_6	5.8e-05
CAD	GOBP_Response_To_Amine	Human	Breast	rep_6	1.4e-04
CAD	GOBP_Ribonucleoside_Monophosphate_Biosynthetic_Process	Human	Breast	rep_6	3.9e-09
CAD	GOBP_Ribonucleoside_Monophosphate_Metabolic_Process	Human	Breast	rep_6	1.9e-12
CAD	GOBP_Small_Molecule_Biosynthetic_Process	Human	Breast	rep_6	1.0e-06
CAD	GOBP_Small_Molecule_Metabolic_Process	Human	Breast	rep_6	5.5e-09
CAD	GOBP_Regeneration	Human	Skin	P2_rep2	5.2e-08
CAD	GOBP_Glycosyl_Compound_Biosynthetic_Process	Human	Skin	P5_rep1	3.2e-09
CAD	GOBP_Nucleobase_Containing_Small_Molecule_Biosynthetic_Process	Human	Skin	P5_rep1	9.1e-10
CAD	GOBP_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Skin	P5_rep1	1.4e-10
CAD	GOBP_Ribose_Phosphate_Biosynthetic_Process	Human	Skin	P5_rep1	4.7e-12
CAD	GOBP_Peptidyl_Threonine_Modification	Human	Skin	P5_rep3	1.4e-09
CAD	GOBP_De_Novo_Pyrimidine_Nucleobase_Biosynthetic_Process	Human	Skin	P9_rep2	4.5e-09
CAD	GOBP_Pyrimidine_Nucleoside_Metabolic_Process	Human	Skin	P9_rep2	1.0e-10
CAD	GOBP_Response_To_Amine	Human	Skin	P10_rep1	1.7e-14
CAD	GOBP_Response_To_Caffeine	Human	Skin	P10_rep2	1.1e-08
CAD	GOBP_Response_To_Cortisol	Human	Skin	P10_rep2	1.4e-14
CAD	GOBP_Utp_Biosynthetic_Process	Human	Skin	P10_rep2	6.0e-10
CAD	GOBP_Utp_Metabolic_Process	Human	Skin	P10_rep2	4.4e-10
CAD	GOBP_Response_To_Lipid	Human	Lung	rep_1	1.8e-09
CAD	GOBP_Response_To_Oxygen_Containing_Compound	Human	Lung	rep_1	7.8e-08

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CAD function as liang/receptor in single cell data

Tissue

Source

SourceCell

Target

TargetCell

PMID

Group

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CAD function as liang/receptor across spatial transcriptomics tissue

Interactions using deconvoluted spatial data.

Ligand

Receptor

LR pair

Tissue

Replication

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Transcription factor for CAD envolved

Transcription factor analysis using single cell data.

Tissue

Group

Cell types

Target genes

Rss score

Motif information.

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Related Drugs for CAD

Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for CAD

Diseases associated with this gene.
(DisGeNet 7.0)

Gene	Disease ID	Disease name	Pubmeds	Source
CAD	C4225320	EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 50	4	CTD_human;GENOMICS_ENGLAND;ORPHANET;UNIPROT
CAD	C0002875	Cooley's anemia	1	CTD_human
CAD	C0002895	Anemia, Sickle Cell	1	CTD_human
CAD	C0005283	beta Thalassemia	1	CTD_human
CAD	C0019025	Hemoglobin F Disease	1	CTD_human
CAD	C0023440	Acute Erythroblastic Leukemia	1	CTD_human
CAD	C0037889	Hereditary spherocytosis	1	CTD_human
CAD	C0085578	Thalassemia Minor	1	CTD_human
CAD	C0271979	Thalassemia Intermedia	1	CTD_human
CAD	C0949116	Congenital hypoplastic anemia	1	CTD_human