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Center for Computational Systems Medicine
Soverview

Gene summary

Soverview

Spatial pattern genes

Soverview

Spatial pattern pathway

Soverview

Cell cell interactions using single cell data

Soverview

Cell-cell/spot-spot interactions using spatial data

Soverview

Transcription factors events

Soverview

Related drugs with this gene

Soverview

Related diseases with this gene

Spatial pattern gene: SLC30A1 (spascer ID:7779)

Gene summary for SLC30A1

check button Gene summary
Gene information
SpeciesHuman
Gene symbol

SLC30A1

Gene ID

7779

Gene namesolute carrier family 30 member 1
SynonymsZNT1|ZRC1
Cytomap1q32.3
Type of geneprotein-coding
Descriptionzinc transporter 1solute carrier family 30 (zinc transporter), member 1znT-1
Modification date20220513
UniProtAcc

Q9Y6M5


check button Gene ontology with evidence Inferred from Direct Assay (IDA) and Biological aspect of Ancestor (IBA).
GeneGO IDGO termPubMed IDCategory
SLC30A1

GO:0005385

zinc ion transmembrane transporter activity

21873635

Function
SLC30A1

GO:0005783

endoplasmic reticulum

21873635

Component
SLC30A1

GO:0005794

Golgi apparatus

21873635

Component
SLC30A1

GO:0006882

cellular zinc ion homeostasis

21873635

Process
SLC30A1

GO:0010312

detoxification of zinc ion

21873635

Process
SLC30A1

GO:0016021

integral component of membrane

21873635

Component
SLC30A1

GO:0019855

calcium channel inhibitor activity

21873635

Function
SLC30A1

GO:0071577

zinc ion transmembrane transport

21873635

Process

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Spatial pattern events for SLC30A1

check buttonspatial pattern gene list.
Gene symbolSpeciesTissueReplicationPMIDAdj p-value
SLC30A1HumanIntestinerep_colon4 344172251.02e-10
SLC30A1HumanLiverrep_liver1 344172251.08e-15
SLC30A1HumanLiverrep_liver2 344172256.98e-16
SLC30A1HumanLiverrep_liver4 344172257.71e-16
SLC30A1HumanIntestineA3 334064091.94e-14
SLC30A1HumanIntestineA6 334064099.85e-07
SLC30A1HumanIntestineA7 334064095.00e-06
SLC30A1HumanBreast1160920F 344938722.88e-08

check buttonspatial pattern gene map.(click to enlarge the image in a new window)

H&E staining (if available)Singel gene map
Intestine_rep_colon4_H&E
boxplot

boxplot
Liver_rep_liver1_H&E
boxplot

boxplot
Liver_rep_liver2_H&E
boxplot

boxplot
Liver_rep_liver4_H&E
boxplot

boxplot
Intestine_A3_H&E
boxplot

boxplot
Intestine_A6_H&E
boxplot

boxplot
Intestine_A7_H&E
boxplot

boxplot
Breast_1160920F_H&E
boxplot

boxplot


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Spatial pattern pathway has SLC30A1 envolved


SymbolPathwaySpeciesTissue typeReplicationP-value
SLC30A1GOBP_Regulation_Of_Transmembrane_TransportHumanBrainrep_1 2.8e-23
SLC30A1GOBP_Regulation_Of_TransportHumanBrainrep_1 3.1e-16
SLC30A1GOBP_Transmembrane_TransportHumanBrainrep_1 2.8e-23
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanBladderrep_2 1.8e-05
SLC30A1GOBP_Response_To_Zinc_IonHumanBladderrep_2 8.5e-05
SLC30A1GOBP_Stress_Response_To_Metal_IonHumanBladderrep_2 1.3e-11
SLC30A1GOBP_Zinc_Ion_HomeostasisHumanBladderrep_2 1.3e-09
SLC30A1GOBP_Regulation_Of_Transmembrane_TransportHumanLiverrep_1 1.0e-70
SLC30A1GOBP_Regulation_Of_TransportHumanLiverrep_1 9.4e-68
SLC30A1GOBP_Transmembrane_TransportHumanLiverrep_1 1.0e-70
SLC30A1GOBP_Regulation_Of_TransportHumanIntestinerep_colon4 1.0e-26
SLC30A1GOBP_Cation_Transmembrane_TransportHumanIntestineA3 3.4e-12
SLC30A1GOBP_Cation_TransportHumanIntestineA3 1.3e-09
SLC30A1GOBP_Cell_Cell_SignalingHumanIntestineA3 6.4e-08
SLC30A1GOBP_Embryo_DevelopmentHumanIntestineA3 2.4e-07
SLC30A1GOBP_Homeostatic_ProcessHumanIntestineA3 8.7e-10
SLC30A1GOBP_Inorganic_Ion_Transmembrane_TransportHumanIntestineA3 1.0e-12
SLC30A1GOBP_Negative_Regulation_Of_Ion_TransportHumanIntestineA3 3.5e-10
SLC30A1GOBP_Negative_Regulation_Of_SignalingHumanIntestineA3 4.9e-15
SLC30A1GOBP_Negative_Regulation_Of_TransportHumanIntestineA3 7.4e-09
SLC30A1GOBP_Regulation_Of_Cation_Transmembrane_TransportHumanIntestineA3 1.7e-08
SLC30A1GOBP_Regulation_Of_Trans_Synaptic_SignalingHumanIntestineA3 4.7e-08
SLC30A1GOBP_Regulation_Of_TransportHumanIntestineA3 4.4e-11
SLC30A1GOBP_Response_To_Inorganic_SubstanceHumanIntestineA3 6.8e-07
SLC30A1GOBP_SecretionHumanIntestineA3 1.8e-13
SLC30A1GOBP_Synaptic_SignalingHumanIntestineA3 5.0e-10
SLC30A1GOBP_Transmembrane_TransportHumanIntestineA3 1.4e-10
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanIntestineA8 2.0e-13
SLC30A1GOBP_Calcium_Ion_ImportHumanIntestineA8 3.7e-19
SLC30A1GOBP_Calcium_Ion_TransportHumanIntestineA8 7.4e-14
SLC30A1GOBP_Cellular_HomeostasisHumanIntestineA8 2.1e-11
SLC30A1GOBP_Cellular_Ion_HomeostasisHumanIntestineA8 4.3e-12
SLC30A1GOBP_Cellular_Transition_Metal_Ion_HomeostasisHumanIntestineA8 1.4e-07
SLC30A1GOBP_Chemical_HomeostasisHumanIntestineA8 1.3e-12
SLC30A1GOBP_DetoxificationHumanIntestineA8 8.7e-17
SLC30A1GOBP_Divalent_Inorganic_Cation_HomeostasisHumanIntestineA8 1.0e-12
SLC30A1GOBP_Import_Across_Plasma_MembraneHumanIntestineA8 8.7e-09
SLC30A1GOBP_Import_Into_CellHumanIntestineA8 4.0e-09
SLC30A1GOBP_Inorganic_Ion_Import_Across_Plasma_MembraneHumanIntestineA8 7.0e-10
SLC30A1GOBP_Ion_HomeostasisHumanIntestineA8 6.1e-15
SLC30A1GOBP_Metal_Ion_HomeostasisHumanIntestineA8 2.2e-10
SLC30A1GOBP_Metal_Ion_TransportHumanIntestineA8 4.1e-10
SLC30A1GOBP_Negative_Regulation_Of_Calcium_Ion_ImportHumanIntestineA8 2.5e-39
SLC30A1GOBP_Negative_Regulation_Of_Calcium_Ion_TransportHumanIntestineA8 6.2e-14
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_SecretionHumanIntestineA8 1.2e-08
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_TransportHumanIntestineA8 3.8e-09
SLC30A1GOBP_Negative_Regulation_Of_SecretionHumanIntestineA8 4.4e-22
SLC30A1GOBP_Negative_Regulation_Of_Synaptic_TransmissionHumanIntestineA8 1.2e-13
SLC30A1GOBP_Negative_Regulation_Of_Transmembrane_TransportHumanIntestineA8 6.9e-14
SLC30A1GOBP_Neurotransmitter_SecretionHumanIntestineA8 3.4e-11
SLC30A1GOBP_Neurotransmitter_TransportHumanIntestineA8 7.1e-13
SLC30A1GOBP_Regulation_Of_Calcium_Ion_ImportHumanIntestineA8 3.8e-12
SLC30A1GOBP_Regulation_Of_Ion_TransportHumanIntestineA8 2.0e-13
SLC30A1GOBP_Regulation_Of_Metal_Ion_TransportHumanIntestineA8 1.2e-14
SLC30A1GOBP_Regulation_Of_Neurotransmitter_LevelsHumanIntestineA8 1.4e-10
SLC30A1GOBP_Regulation_Of_SecretionHumanIntestineA8 2.2e-15
SLC30A1GOBP_Regulation_Of_Transmembrane_TransportHumanIntestineA8 1.1e-08
SLC30A1GOBP_Response_To_Cadmium_IonHumanIntestineA8 2.1e-09
SLC30A1GOBP_Response_To_Metal_IonHumanIntestineA8 2.1e-21
SLC30A1GOBP_Response_To_Toxic_SubstanceHumanIntestineA8 8.6e-21
SLC30A1GOBP_Response_To_Zinc_IonHumanIntestineA8 5.0e-16
SLC30A1GOBP_Signal_ReleaseHumanIntestineA8 6.9e-14
SLC30A1GOBP_Stress_Response_To_Metal_IonHumanIntestineA8 2.0e-13
SLC30A1GOBP_Zinc_Ion_HomeostasisHumanIntestineA8 3.2e-15
SLC30A1GOBP_Zinc_Ion_Import_Across_Plasma_MembraneHumanIntestineA8 2.6e-09
SLC30A1GOBP_Zinc_Ion_TransportHumanIntestineA8 4.8e-10
SLC30A1GOBP_Calcium_Ion_ImportHumanPancreasPDAC-B-st1 4.5e-05
SLC30A1GOBP_Negative_Regulation_Of_SignalingHumanPancreasPDAC-B-st1 1.7e-05
SLC30A1GOBP_Negative_Regulation_Of_Transmembrane_TransportHumanPancreasPDAC-B-st1 8.1e-05
SLC30A1GOBP_Neurotransmitter_TransportHumanPancreasPDAC-B-st1 5.7e-05
SLC30A1GOBP_Regulation_Of_Neurotransmitter_LevelsHumanPancreasPDAC-B-st1 8.5e-06
SLC30A1GOBP_Regulation_Of_Trans_Synaptic_SignalingHumanPancreasPDAC-B-st1 5.9e-05
SLC30A1GOBP_Transition_Metal_Ion_HomeostasisHumanPancreasPDAC-B-st1 1.1e-05
SLC30A1GOBP_Import_Into_CellHumanPancreasPDAC-A-st2 2.3e-05
SLC30A1GOBP_Zinc_Ion_HomeostasisHumanPancreasPDAC-A-st2 1.5e-05
SLC30A1GOBP_Zinc_Ion_TransportHumanPancreasPDAC-A-st2 2.2e-06
SLC30A1GOBP_Neurotransmitter_TransportHumanUterusrep_1 4.8e-08
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanUterusrep_25 5.1e-07
SLC30A1GOBP_Regulation_Of_Calcium_Ion_ImportHumanUterusrep_25 2.2e-11
SLC30A1GOBP_Stress_Response_To_Metal_IonHumanUterusrep_25 9.7e-11
SLC30A1GOBP_Zinc_Ion_Import_Across_Plasma_MembraneHumanUterusrep_25 1.6e-09
SLC30A1GOBP_Zinc_Ion_TransportHumanUterusrep_25 2.0e-07
SLC30A1GOBP_Calcium_Ion_ImportHumanUterusrep_26 1.7e-08
SLC30A1GOBP_Calcium_Ion_TransportHumanUterusrep_26 5.1e-08
SLC30A1GOBP_Homeostatic_ProcessHumanUterusrep_26 1.9e-07
SLC30A1GOBP_Inorganic_Ion_Transmembrane_TransportHumanUterusrep_26 6.1e-08
SLC30A1GOBP_Negative_Regulation_Of_Calcium_Ion_TransportHumanUterusrep_26 5.2e-12
SLC30A1GOBP_Negative_Regulation_Of_TransportHumanUterusrep_26 1.0e-12
SLC30A1GOBP_Regulation_Of_Neurotransmitter_TransportHumanUterusrep_26 1.9e-08
SLC30A1GOBP_Regulation_Of_SecretionHumanUterusrep_26 1.7e-06
SLC30A1GOBP_Regulation_Of_Trans_Synaptic_SignalingHumanUterusrep_26 1.2e-08
SLC30A1GOBP_Response_To_Toxic_SubstanceHumanUterusrep_26 4.2e-06
SLC30A1GOBP_Synaptic_SignalingHumanUterusrep_26 3.3e-08
SLC30A1GOBP_Transition_Metal_Ion_TransportHumanUterusrep_26 1.3e-06
SLC30A1GOBP_Negative_Regulation_Of_SignalingHumanUterusrep_29 5.3e-06
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanBreastrep_1 1.2e-08
SLC30A1GOBP_Calcium_Ion_TransportHumanBreastrep_1 5.4e-24
SLC30A1GOBP_Cation_Transmembrane_TransportHumanBreastrep_1 3.6e-30
SLC30A1GOBP_Cation_TransportHumanBreastrep_1 8.4e-53
SLC30A1GOBP_Cellular_HomeostasisHumanBreastrep_1 2.8e-10
SLC30A1GOBP_Cellular_Ion_HomeostasisHumanBreastrep_1 7.6e-24
SLC30A1GOBP_Cellular_Transition_Metal_Ion_HomeostasisHumanBreastrep_1 6.0e-07
SLC30A1GOBP_Chemical_HomeostasisHumanBreastrep_1 4.8e-18
SLC30A1GOBP_Divalent_Inorganic_Cation_HomeostasisHumanBreastrep_1 1.2e-25
SLC30A1GOBP_Embryo_Development_Ending_In_Birth_Or_Egg_HatchingHumanBreastrep_1 7.7e-07
SLC30A1GOBP_Homeostatic_ProcessHumanBreastrep_1 9.0e-53
SLC30A1GOBP_Import_Across_Plasma_MembraneHumanBreastrep_1 4.4e-09
SLC30A1GOBP_Import_Into_CellHumanBreastrep_1 2.0e-94
SLC30A1GOBP_In_Utero_Embryonic_DevelopmentHumanBreastrep_1 1.5e-18
SLC30A1GOBP_Inorganic_Ion_Transmembrane_TransportHumanBreastrep_1 1.9e-35
SLC30A1GOBP_Ion_HomeostasisHumanBreastrep_1 1.4e-53
SLC30A1GOBP_Metal_Ion_HomeostasisHumanBreastrep_1 6.8e-70
SLC30A1GOBP_Metal_Ion_TransportHumanBreastrep_1 7.5e-64
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_SecretionHumanBreastrep_1 2.4e-32
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_TransportHumanBreastrep_1 3.3e-51
SLC30A1GOBP_Negative_Regulation_Of_SecretionHumanBreastrep_1 3.8e-30
SLC30A1GOBP_Negative_Regulation_Of_Synaptic_TransmissionHumanBreastrep_1 5.5e-31
SLC30A1GOBP_Regulation_Of_Calcium_Ion_ImportHumanBreastrep_1 6.4e-09
SLC30A1GOBP_Regulation_Of_Cation_Transmembrane_TransportHumanBreastrep_1 1.0e-13
SLC30A1GOBP_Regulation_Of_Ion_TransportHumanBreastrep_1 1.7e-09
SLC30A1GOBP_Regulation_Of_Metal_Ion_TransportHumanBreastrep_1 1.5e-62
SLC30A1GOBP_Regulation_Of_SecretionHumanBreastrep_1 1.1e-10
SLC30A1GOBP_Regulation_Of_Transmembrane_TransportHumanBreastrep_1 1.6e-85
SLC30A1GOBP_Regulation_Of_TransportHumanBreastrep_1 3.7e-17
SLC30A1GOBP_Response_To_Metal_IonHumanBreastrep_1 3.0e-20
SLC30A1GOBP_SecretionHumanBreastrep_1 9.7e-57
SLC30A1GOBP_Synaptic_SignalingHumanBreastrep_1 3.5e-04
SLC30A1GOBP_Transition_Metal_Ion_HomeostasisHumanBreastrep_1 1.1e-30
SLC30A1GOBP_Transmembrane_TransportHumanBreastrep_1 3.2e-56
SLC30A1GOBP_Calcium_Ion_ImportHumanBreastrep_5 1.3e-06
SLC30A1GOBP_DetoxificationHumanBreastrep_5 5.6e-07
SLC30A1GOBP_Embryo_DevelopmentHumanBreastrep_5 5.5e-08
SLC30A1GOBP_Inorganic_Ion_Import_Across_Plasma_MembraneHumanBreastrep_5 1.5e-05
SLC30A1GOBP_Negative_Regulation_Of_SignalingHumanBreastrep_5 8.6e-14
SLC30A1GOBP_Negative_Regulation_Of_TransportHumanBreastrep_5 5.7e-12
SLC30A1GOBP_Neurotransmitter_SecretionHumanBreastrep_5 1.5e-04
SLC30A1GOBP_Regulation_Of_Neurotransmitter_LevelsHumanBreastrep_5 2.2e-04
SLC30A1GOBP_Response_To_Inorganic_SubstanceHumanBreastrep_5 1.8e-10
SLC30A1GOBP_Response_To_Toxic_SubstanceHumanBreastrep_5 1.2e-07
SLC30A1GOBP_Signal_ReleaseHumanBreastrep_5 1.1e-10
SLC30A1GOBP_Cell_Cell_SignalingHumanBreastrep_6 5.0e-05
SLC30A1GOBP_Negative_Regulation_Of_Calcium_Ion_ImportHumanBreastrep_6 9.2e-11
SLC30A1GOBP_Negative_Regulation_Of_Ion_TransportHumanBreastrep_6 1.0e-08
SLC30A1GOBP_Negative_Regulation_Of_Transmembrane_TransportHumanBreastrep_6 1.6e-09
SLC30A1GOBP_Neurotransmitter_TransportHumanBreastrep_6 9.5e-06
SLC30A1GOBP_Regulation_Of_Trans_Synaptic_SignalingHumanBreastrep_6 1.3e-06
SLC30A1GOBP_Response_To_Cadmium_IonHumanBreastrep_6 7.8e-04
SLC30A1GOBP_Zinc_Ion_HomeostasisHumanBreastrep_6 3.5e-08
SLC30A1GOBP_Zinc_Ion_Import_Across_Plasma_MembraneHumanBreastrep_6 3.5e-07
SLC30A1GOBP_Zinc_Ion_TransportHumanBreastrep_6 4.9e-11
SLC30A1GOBP_Import_Across_Plasma_MembraneHumanSkinP2_rep2 6.7e-13
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_SecretionHumanSkinP2_rep2 8.5e-12
SLC30A1GOBP_Negative_Regulation_Of_Neurotransmitter_TransportHumanSkinP2_rep2 7.6e-09
SLC30A1GOBP_Negative_Regulation_Of_Transmembrane_TransportHumanSkinP2_rep2 6.2e-12
SLC30A1GOBP_Response_To_Cadmium_IonHumanSkinP2_rep2 2.1e-08
SLC30A1GOBP_Divalent_Inorganic_Cation_HomeostasisHumanSkinP2_rep3 1.3e-08
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanSkinP10_rep1 1.5e-20
SLC30A1GOBP_Negative_Regulation_Of_Synaptic_TransmissionHumanSkinP10_rep2 3.9e-09
SLC30A1GOBP_Cadmium_Ion_Transmembrane_TransportHumanLungrep_1 2.0e-09
SLC30A1GOBP_Ion_HomeostasisHumanLungrep_1 6.1e-07
SLC30A1GOBP_Transition_Metal_Ion_TransportHumanLungrep_1 6.8e-07
SLC30A1GOBP_Cellular_HomeostasisHumanLungrep_2 7.3e-07
SLC30A1GOBP_Cellular_Transition_Metal_Ion_HomeostasisHumanLungrep_2 5.1e-07
SLC30A1GOBP_Metal_Ion_TransportHumanLungrep_2 1.6e-07
SLC30A1GOBP_Negative_Regulation_Of_SecretionHumanLungrep_2 3.7e-07
SLC30A1GOBP_Regulation_Of_SecretionHumanLungrep_2 9.3e-09

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SLC30A1 function as liang/receptor in single cell data

TissueSourceSourceCellTargetTargetCellPMIDGroup

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SLC30A1 function as liang/receptor across spatial transcriptomics tissue

check button Interactions using deconvoluted spatial data.

LigandReceptor LR pairTissueReplication

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Transcription factor for SLC30A1 envolved

check buttonTranscription factor analysis using single cell data.
TFTissueGroupCell typesTarget genesRss score

check button Motif information.

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Related Drugs for SLC30A1

check button Approved drugs targeting this gene.
(DrugBank Version 5.1.9 2022-01-04)
GeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for SLC30A1

check button Diseases associated with this gene.
(DisGeNet 7.0)
GeneDisease IDDisease namePubmedsSource